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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 1
1958 1
1960 2
1961 3
1962 4
1963 10
1964 9
1965 2
1966 1
1973 1
1975 1
1977 1
1978 3
1979 152
1980 318
1981 303
1982 271
1983 298
1984 353
1985 478
1986 691
1987 839
1988 897
1989 835
1990 887
1991 948
1992 1164
1993 1383
1994 1475
1995 1559
1996 1584
1997 1638
1998 1527
1999 1574
2000 1473
2001 1677
2002 1827
2003 1828
2004 1877
2005 2114
2006 2152
2007 2236
2008 2190
2009 2050
2010 2004
2011 2236
2012 2540
2013 2422
2014 2336
2015 2481
2016 2207
2017 2010
2018 1661
2019 791
2020 9
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55,206 results
Results by year
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Page 1
Genetic Markers of Alzheimer's Disease.
Nikolac Perkovic M and Pivac N. Adv Exp Med Biol 2019 - Review. PMID 31705489
Genetic and genomic studies offer insight into many additional genetic risk loci involved in the genetically complex nature of late-onset Alzheimer's disease. ...Therefore, the use of genetic markers of Alzheimer's disease, for monitoring development, time course, treatment response, and prognosis of Alzheimer's disease, is still far away from the clinical application, because the contribution of genetic variations to the relative risk of developing Alzheimer's disease is limited. ...
Genetic and genomic studies offer insight into many additional genetic risk loci involved in the genetically complex nature of
Genetic Markers in Psychiatry.
Nedic Erjavec G, et al. Adv Exp Med Biol 2019. PMID 31705490
Therefore, it is difficult to uncover new set of genes and possible genetic markers of these disorders since the understanding of the molecular imbalance leading to these disorders is not complete. ...Therefore, novel genetic approaches based on systems biology focused on improvement of the identification of the biological underpinnings might offer genetic markers of addiction, depression, eating disorders, schizophrenia, and PTSD. ...
Therefore, it is difficult to uncover new set of genes and possible genetic markers of these disorders since the understanding …
Genetic Markers of ADHD-Related Variations in Intracranial Volume.
Klein M, et al. Am J Psychiatry 2019. PMID 30818988
The authors investigated the overlap between common genetic variation associated with ADHD risk and these brain volume measures to identify underlying biological processes contributing to the disorder. ...CONCLUSIONS: This is the first genome-wide study to show significant genetic overlap between brain volume measures and ADHD, both on the global and the single variant level. ...
The authors investigated the overlap between common genetic variation associated with ADHD risk and these brain volume measures to id …
[Search for genetic markers for precise diagnostics of keratoconus].
Skorodumova LO, et al. Biomed Khim 2019 - Review. PMID 30816092 Russian.
Currently, the role of genetic factors in keratoconus development has been proven. This indicates the possibility of diagnostics of subclinical and forme fruste keratoconus using genetic markers. ...The studies of causal mutations indicate the genetic heterogeneity of keratoconus, which complicates the development of a diagnostic panel. ...
Currently, the role of genetic factors in keratoconus development has been proven. This indicates the possibility of diagnostics of s …
[Genetic Markers for Personalized Therapy of Polygenic Diseases: Pharmacogenetics of Multiple Sclerosis].
Tsareva EY, et al. Mol Biol (Mosk) 2019 - Review. PMID 31397433 Russian. Free article.
Prognostic genetic biomarkers of treatment efficacy can help to identify the MS patient groups where a particular drug is preferential or even strictly indicated to use. ...
Prognostic genetic biomarkers of treatment efficacy can help to identify the MS patient groups where a particular drug is preferentia …
Genetics without genes? The centrality of genetic markers in livestock genetics and genomics.
Lowe JWE and Bruce A. Hist Philos Life Sci 2019. PMID 31659490
In this paper, rather than focusing on genes as an organising concept around which historical considerations of theory and practice in genetics are elucidated, we place genetic markers at the heart of our analysis. ...We define a genetic marker as a (usually material) element existing in different forms in the genome, that can be identified and mapped using a variety (and often combination) of quantitative, classical and molecular genetic techniques. ...
In this paper, rather than focusing on genes as an organising concept around which historical considerations of theory and practice in genet …
Genetic markers associated with clinical and radiographic response in adalimumab plus methotrexate- or methotrexate-treated rheumatoid arthritis patients in OPTIMA.
Skapenko A, et al. Clin Exp Rheumatol 2019. PMID 30963994 Free article.
Because the clinical course of RA and response to therapy may be influenced by the genetic background of the patient, the objective of this retrospective parallel-assigned case-control analysis was to evaluate the associations between candidate genetic markers for RA with clinical and radiographic responses to ADA + methotrexate (MTX) or MTX monotherapy in the Optimal Protocol for Treatment Initiation with MTX and ADA (OPTIMA) study. METHODS: Three candidate genetic markers were tested: HLA-DRB1 shared epitope (SE), interleukin 4 receptor (IL4R) single nucleotide polymorphism (SNP) rs1805010, and Fc gamma receptor IIb (FcgRIIb) SNP rs1050501. ...
Because the clinical course of RA and response to therapy may be influenced by the genetic background of the patient, the objective o …
Redefining the IBDs using genome-scale molecular phenotyping
Furey TS, et al. Nat Rev Gastroenterol Hepatol 2019 - Review. PMID 30787446
Genome-wide association studies have identified >240 loci that confer risk of IBD, but the clinical utility of these findings remains unclear, and mechanisms by which the genetic variants contribute to disease are largely unknown. ...
Genome-wide association studies have identified >240 loci that confer risk of IBD, but the clinical utility of these findings remains unc …
55,206 results
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