Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 18
2001 81
2002 159
2003 228
2004 368
2005 408
2006 482
2007 550
2008 613
2009 589
2010 557
2011 592
2012 616
2013 626
2014 512
2015 484
2016 471
2017 475
2018 387
2019 163
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

7,199 results
Results by year
Filters applied: . Clear all
Page 1
Ghrelin regulation of glucose metabolism.
Poher AL, et al. Peptides 2018 - Review. PMID 29412824 Free PMC article.
The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH) releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and adiposity by acting on the hypothalamic melanocortinergic system. Subsequently, ghrelin was found to exert a series of metabolic effects, overall testifying ghrelin a pleiotropic nature of broad pharmacological interest. ...
The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH) releasing peptide. Soon after its discovery, g
Ghrelin and Obesity: Identifying Gaps and Dispelling Myths. A Reappraisal.
Makris MC, et al. In Vivo 2017 - Review. PMID 29102924 Free PMC article.
Ghrelin is a hormone known to stimulate appetite. There are numerous possible actions through which ghrelin exerts its effect in the body: a) Overproduction of ghrelin, b) reduced ghrelin following meals, and c) increased receptor sensitivity to ghrelin action. Sleeve gastrectomy, a bariatric procedure, leads to reduction of ghrelin levels and subsequently to weight loss. However, there are many limitations to measurement of the fasting plasma level of the active form of ghrelin. ...
Ghrelin is a hormone known to stimulate appetite. There are numerous possible actions through which ghrelin exerts its effect
LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Ge X, et al. Cell Metab 2018. PMID 29233536 Free article.
Though the biology mediated by ghrelin has been described in great detail, regulation of ghrelin action is poorly understood. ...LEAP2 fully inhibits GHSR activation by ghrelin and blocks the major effects of ghrelin in vivo, including food intake, GH release, and maintenance of viable glucose levels during chronic caloric restriction. ...
Though the biology mediated by ghrelin has been described in great detail, regulation of ghrelin action is poorly understood. …
The Homeostatic Force of Ghrelin.
Yanagi S, et al. Cell Metab 2018 - Review. PMID 29576534 Free article.
Ghrelin operates brain circuits to regulate homeostatic and hedonic feeding. Recent research advances have shed new light on ghrelin's multifaceted roles in cellular homeostasis, which could maintain the internal environment and overcome metaflammation in metabolic organs. ...Future studies of ghrelin will further elucidate how the stomach regulates systemic homeostasis....
Ghrelin operates brain circuits to regulate homeostatic and hedonic feeding. Recent research advances have shed new light on ghrel
Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism.
Lv Y, et al. Biosci Rep 2018 - Review. PMID 30177523 Free PMC article.
Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the released growth hormone secretagogue receptor (GHSR). Ghrelin has been isolated from human and rat stomach and is also detected in the hypothalamic arcuate nucleus. Ghrelin receptor is primarily located in the neuropeptide Y and agouti-related protein neurons. ...
Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the released growth hormone secretagogue receptor
Ghrelin as a Survival Hormone.
Mani BK and Zigman JM. Trends Endocrinol Metab 2017 - Review. PMID 29097101 Free PMC article.
Ghrelin administration induces food intake and body weight gain. Based on these actions, the ghrelin system was initially proposed as an antiobesity target. Subsequent studies using genetic mouse models have raised doubts about the role of the endogenous ghrelin system in mediating body weight homeostasis or obesity. ...
Ghrelin administration induces food intake and body weight gain. Based on these actions, the ghrelin system was initially prop
The Role of Ghrelin in Anorexia Nervosa.
Schalla MA and Stengel A. Int J Mol Sci 2018 - Review. PMID 30037011 Free PMC article.
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the stomach, is the only known peripherally produced and centrally acting peptide that stimulates food intake and therefore attracted a lot of attention with one major focus on the treatment of conditions where an increased energy intake or body weight gain is desired. ...Ghrelin signaling has been thoroughly investigated under conditions of anorexia nervosa. The present review will highlight these alterations of ghrelin in anorexia and discuss possible treatment strategies targeting ghrelin signaling. ...
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the stomach, is the only known peripherally produce
Ghrelin's Relationship to Blood Glucose.
Mani BK, et al. Endocrinology 2019 - Review. PMID 30874792 Free PMC article.
Much effort has been directed at studying the orexigenic actions of administered ghrelin and the potential effects of the endogenous ghrelin system on food intake, food reward, body weight, adiposity, and energy expenditure. ...Also of interest, blood glucose negatively regulates ghrelin secretion. This article reviews the literature suggesting the existence of a blood glucose-ghrelin axis and highlights the factors that mediate the glucoregulatory actions of ghrelin, especially during metabolic extremes such as starvation and diabetes....
Much effort has been directed at studying the orexigenic actions of administered ghrelin and the potential effects of the endogenous …
Anxiety, Depression, and the Microbiome: A Role for Gut Peptides
Lach G, et al. Neurotherapeutics 2018 - Review. PMID 29134359 Free PMC article.
Here, we summarize the potential interactions of the microbiota with gut hormones and endocrine peptides, including neuropeptide Y, peptide YY, pancreatic polypeptide, cholecystokinin, glucagon-like peptide, corticotropin-releasing factor, oxytocin, and ghrelin in microbiome-to-brain signaling. ...
Here, we summarize the potential interactions of the microbiota with gut hormones and endocrine peptides, including neuropeptide Y, peptide …
Ghrelin and the heart.
Tokudome T, et al. Peptides 2019 - Review. PMID 29791869
In ghrelin-deficient mice, both exogenous and endogenous ghrelin protects against fatal arrhythmia and promotes remodeling after myocardial infarction. ...Therefore, ghrelin is a promising novel therapeutic agent for cardiac disease....
In ghrelin-deficient mice, both exogenous and endogenous ghrelin protects against fatal arrhythmia and promotes remodeling aft …
7,199 results
Jump to page
Feedback