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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1971 7
1972 22
1973 24
1974 24
1975 36
1976 30
1977 47
1978 34
1979 35
1980 34
1981 37
1982 29
1983 39
1984 42
1985 53
1986 50
1987 60
1988 50
1989 65
1990 59
1991 60
1992 72
1993 62
1994 63
1995 79
1996 86
1997 60
1998 84
1999 50
2000 72
2001 61
2002 55
2003 76
2004 82
2005 70
2006 84
2007 77
2008 93
2009 90
2010 133
2011 138
2012 159
2013 170
2014 135
2015 150
2016 147
2017 135
2018 135
2019 107
2020 9
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3,237 results
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Page 1
Gingival crevicular fluid as a source of biomarkers for periodontitis.
Barros SP, et al. Periodontol 2000 2016 - Review. PMID 26662482 Free PMC article.
As host susceptibility is a critical determinant in periodontal disease pathogenesis, the inflammatory mediator levels present in gingival crevicular fluid represent relevant risk indicators for disease activity. ...More recently, gingival crevicular fluid metabolomics appears promising as an additional diagnostic method. Biofilm structure and the host inflammatory response to the microbial challenge may induce specific inflammatory signatures. ...
As host susceptibility is a critical determinant in periodontal disease pathogenesis, the inflammatory mediator levels present in gingiva
Gingival crevicular fluid and saliva.
Taylor JJ and Preshaw PM. Periodontol 2000 2016 - Review. PMID 26662478
This volume of Periodontology 2000 considers the role of gingival crevicular fluid and saliva in physiological function, maintenance of oral tissue integrity, defense against pathogens and oral disease as well as the many, emerging applications of analysis of these fluids in support of periodontal disease diagnosis, prognosis and epidemiology. ...
This volume of Periodontology 2000 considers the role of gingival crevicular fluid and saliva in physiological function …
Gingival crevicular fluid and its immune mediators in the proteomic era.
Bostanci N and Belibasakis GN. Periodontol 2000 2018 - Review. PMID 29193353
The gingival crevicular fluid is a biological medium suitable for identifying and measuring such biomarkers because it can be easily and noninvasively sampled from the immediate vicinity of the affected tissues. ...Hence, such technologies provide a broad qualitative and quantitative insight of the proteins present in gingival crevicular fluid. ...
The gingival crevicular fluid is a biological medium suitable for identifying and measuring such biomarkers because it …
Current Status of Proteomic Technologies for Discovering and Identifying Gingival Crevicular Fluid Biomarkers for Periodontal Disease.
Tsuchida S, et al. Int J Mol Sci 2018 - Review. PMID 30587811 Free PMC article.
As a fluid lying in close proximity to the periodontal tissue, the gingival crevicular fluid (GCF) is the principal target in the search for periodontal disease biomarkers because its protein composition may reflect the disease pathophysiology. ...
As a fluid lying in close proximity to the periodontal tissue, the gingival crevicular fluid (GCF) is the princi …
Clinical and technical considerations in the analysis of gingival crevicular fluid.
Wassall RR and Preshaw PM. Periodontol 2000 2016 - Review. PMID 26662483
Despite the technical challenges involved when collecting, processing and analyzing gingival crevicular fluid samples, research using gingival crevicular fluid has, and will continue to play, a fundamental role in expanding our understanding of periodontal pathogenesis and healing outcomes following treatment. ...Only with clear and transparent reporting will the full impact of future gingival crevicular fluid research be realized. This paper discusses the complexities of gingival crevicular fluid collection and analysis and provides guidance to researchers working in this field....
Despite the technical challenges involved when collecting, processing and analyzing gingival crevicular fluid samples, …
Gingivitis
Page RC. J Clin Periodontol 1986 - Review. PMID 3522644
Gingivitis is caused by substances derived from microbial plaque accumulating at or near the gingival sulcus; all other suspected local and systemic etiologic factors either enhance plaque accumulation or retention, or enhance the susceptibility of the gingival tissue to microbial attack. Microbial species specifically associated with gingival health include Streptococcus sanguis 1, S. D-7, and Fusobacterium naviforme. ...
Gingivitis is caused by substances derived from microbial plaque accumulating at or near the gingival sulcus; all other suspected loc …
Low-level laser therapy increases interleukin-1β in gingival crevicular fluid and enhances the rate of orthodontic tooth movement.
Varella AM, et al. Am J Orthod Dentofacial Orthop 2018. PMID 30268264
INTRODUCTION: The aim of this investigation was to evaluate the effects of low-level laser therapy on interleukin-1β (IL-1β) levels in gingival crevicular fluid and its correlation with orthodontic tooth movement. ...Gingival crevicular fluid was collected at 5 time points from the control and experimental sides, and the levels of IL-1β were analyzed by enzyme-linked immuno-sorbent assay (ELISA). ...
INTRODUCTION: The aim of this investigation was to evaluate the effects of low-level laser therapy on interleukin-1β (IL-1β) levels in gi
Diagnostic potential and future directions of biomarkers in gingival crevicular fluid and saliva of periodontal diseases: Review of the current evidence.
Ghallab NA. Arch Oral Biol 2018 - Review. PMID 29288920
In the field of periodontal diagnostics, oral fluid-based biomarkers have been studied mainly in the gingival crevicular fluid (GCF) and saliva. ...
In the field of periodontal diagnostics, oral fluid-based biomarkers have been studied mainly in the gingival crevicular
Identification of Gingival Crevicular Fluid Sampling, Analytical Methods, and Oral Biomarkers for the Diagnosis and Monitoring of Periodontal Diseases: A Systematic Review.
Nazar Majeed Z, et al. Dis Markers 2016 - Review. PMID 28074077 Free PMC article.
To evaluate from current scientific literature the most common and precise method for gingival crevicular fluid (GCF) sample collection, biomarker analytical methods, and the variability of biomarker quantification, even when using the same analytical technique. ...Furthermore, paper strips are the most convenient and accurate method for gingival crevicular fluid collection, while enzyme-linked immunosorbent assay can be considered the most conventional method for the diagnosis of biofluids....
To evaluate from current scientific literature the most common and precise method for gingival crevicular fluid (GCF) s …
Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease.
Balli U, et al. J Periodontal Res 2015. PMID 25529858
Gingival crevicular fluid and serum samples were collected and periostin levels were determined using the enzyme-linked immunosorbent assay. ...Periostin in gingival crevicular fluid negatively correlated with the gingival index in the periodontal disease groups, whereas it is inversely correlated with the clinical attachment level only in the periodontitis group (p < 0.05). ...
Gingival crevicular fluid and serum samples were collected and periostin levels were determined using the enzyme-linked
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