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Can gingival crevicular blood be relied upon for assessment of blood glucose level?
Dwivedi S, et al. N Y State Dent J 2014 - Clinical Trial. PMID 25675614
Diabetes mellitus (DM) is undiagnosed in approximately half of the patients actually suffering from the disease. In addition, the prevalence of DM is more than twice as high as in patients with periodontitis when compared to periodontally healthy subjects. Thus, a high number of patients with periodontitis may have undiagnosed DM. The purpose of the present study was to evaluate whether blood oozing from a gingival crevice during routine periodontal examination can be used for determining glucose levels. ...
Diabetes mellitus (DM) is undiagnosed in approximately half of the patients actually suffering from the disease. In addition, the pre …
Gingival crevicular blood as a source to screen for diabetes control in a dental office setting.
Kim JW, et al. Am J Dent 2015. PMID 26087569
screen for diabetes control, this study compared glycosylated hemoglobin (HbAlc) levels found in GCB and serum. Methods: Patients diagnosed (n= 29), with diabetes received a venipuncture on the finger and serum blood (METHODS) obtained was tested for HbAlc status chair-side. ...Furthermore, the HbAlc values were independent of the gingival sites used for collection with intra-patient GCB values exhibiting a correlation value between sites of 0.91 (P< 0.0001)....
screen for diabetes control, this study compared glycosylated hemoglobin (HbAlc) levels found in GCB and serum. Methods: Patie …
The potential use of gingival crevicular blood for measuring glucose to screen for diabetes: an examination based on characteristics of the blood collection site.
Strauss SM, et al. J Periodontol 2009. PMID 19485820
Group 1 participants had blood collected from sites with adequate BOP to obtain a sample without touching the tooth or gingival margin, whereas group 2 participants had blood collected from sites with little or no bleeding. ...CONCLUSION: GCB samples were suitable to screen for diabetes in persons with sufficient BOP to obtain a sample without touching the tooth or gingival margin (i.e., in patients having the basic clinical signs of gingivitis or periodontal disease)....
Group 1 participants had blood collected from sites with adequate BOP to obtain a sample without touching the tooth or gingival
Juvenile dermatomyositis: is periodontal disease associated with dyslipidemia?
Kozu KT, et al. Adv Rheumatol 2018. PMID 30657104
Gingival vasculopathy pattern was significantly higher in the former group (60% vs. 0%,p = 0.0001), as well as the median of gingival bleeding index (GBI) [24.1(4.2-69.4) vs. 11.1(0-66.6)%,p = 0.001] and probing pocket depth (PPD) [1.7(0.6-2.4) vs.1.4(0-2.12)mm,p = 0.006]. ...CONCLUSION: Our study showed that gingival inflammation seems to be related to dyslipidemia in JDM patients, suggesting underlying mechanisms for both complications....
Gingival vasculopathy pattern was significantly higher in the former group (60% vs. 0%,p = 0.0001), as well as the median of
Periodontal status and serum biomarkers levels in haemodialysis patients.
Rodrigues VP, et al. J Clin Periodontol 2014 - Clinical Trial. PMID 24930744
AIM: To investigate the association between periodontal status and serum biomarkers levels in haemodialysis patients. METHODS: This cross-sectional study included 96 haemodialysis patients. The periodontal evaluation was realized using clinical attachment level (CAL), probing depth (PD), gingival bleeding index (GBI), visible plaque index (VPI) and gingival index (GI). ...
AIM: To investigate the association between periodontal status and serum biomarkers levels in haemodialysis patients. METHODS: This c …
Correlation between leptin and the health of the gingiva: a predictor of medical risk.
Gangadhar V, et al. Indian J Dent Res 2011. PMID 22124048 Free article.
AIMS: The present study was done to correlate the concentrations of leptin and interleukin (IL)-6 within the gingiva in healthy, gingivitis and periodontitis groups of patients and to correlate gingival leptin and IL-6 concentrations with plasma leptin and IL-6 concentrations in the healthy, gingivitis and periodontitis groups of patients. ...PATIENTS AND METHODS: Seventy-five patients in the age group of 18-60 years were selected and grouped based on the gingival index (Loe and Sillness) and their clinical attachment levels into healthy, gingivitis and periodontitis groups. ...
AIMS: The present study was done to correlate the concentrations of leptin and interleukin (IL)-6 within the gingiva in healthy, ging …
Correlation between levels of sulcular and capillary blood glucose
Ardakani MR, et al. J Contemp Dent Pract 2009. Among authors: Haerian A, Hashemzadeh M. PMID 19279967
Blood was collected using a 1.6-1.8 mm diameter micro bite collection tube to transport the sample from the gingival sulci of anterior teeth following periodontal pocket probing to a test strip of a glucose self-monitoring device. ...RESULTS: The blood glucose levels in patients ranged from 58 mg/dl to 477 mg/dl, and the values of blood samples taken from gingival sulcus or finger tip of the same patient showed a very high intra-patient correlation (r =0.99, p< 0.0001). ...
Blood was collected using a 1.6-1.8 mm diameter micro bite collection tube to transport the sample from the gingival sulci of anterio …
Factor X M402T: a homozygous missense mutation identified as the cause of cross-reacting material-reduced deficiency.
Chikasawa Y, et al. Int J Hematol 2014 - Clinical Trial. Among authors: Hagiwara T. PMID 25064371
We investigated a mildly hemorrhagic patient with factor X (FX) deficiency to identify the nature of his defect by comprehensive analyses. A 42-year-old Japanese man was admitted to our hospital for uncontrolled gingival hemorrhage. His FX activity based on prothrombin time (PT) and activated partial thromboplastin time (aPTT) and FX antigen were <1, 6.5 and 11 %, respectively. ...
We investigated a mildly hemorrhagic patient with factor X (FX) deficiency to identify the nature of his defect by comprehensi …
The impact of smoking status on antioxidant enzyme activity and malondialdehyde levels in chronic periodontitis
Tonguç MÖ, et al. J Periodontol 2011. PMID 21219099
After the clinical measurements, serum and gingival tissue samples were collected. SOD, GSH-Px, and CAT activities and MDA levels in hemolysates and gingival tissue samples were spectrophotometrically assayed. ...Gingival tissue MDA levels in the periodontitis groups were significantly higher than that in the control group (P <0.01). However, the control group had the highest gingival SOD, GSH-Px, and CAT activities compared with all the periodontitis groups (P <0.01). ...
After the clinical measurements, serum and gingival tissue samples were collected. SOD, GSH-Px, and CAT activities and MDA levels in …
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