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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 15
1797 59
1798 15
1799 291
1800 377
1801 361
1802 283
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 409
1829 568
1830 510
1831 579
1832 284
1833 221
1834 209
1835 222
1836 220
1837 281
1838 265
1839 289
1840 395
1841 829
1842 971
1843 813
1844 609
1845 681
1846 746
1847 774
1848 799
1849 744
1850 756
1851 774
1852 765
1853 901
1854 827
1855 1092
1856 1283
1857 1275
1858 1339
1859 1319
1860 1210
1861 946
1862 905
1863 823
1864 938
1865 937
1866 1238
1867 1436
1868 1511
1869 1534
1870 1477
1871 1856
1872 1921
1873 1984
1874 2121
1875 2098
1876 1892
1877 1968
1878 2201
1879 2138
1880 2407
1881 2579
1882 2110
1883 2572
1884 2604
1885 2822
1886 2954
1887 3414
1888 3358
1889 3753
1890 3614
1891 3224
1892 3720
1893 3962
1894 3432
1895 3684
1896 3859
1897 4123
1898 4081
1899 3568
1900 3398
1901 3501
1902 3539
1903 3535
1904 3728
1905 3743
1906 3618
1907 4106
1908 4306
1909 4527
1910 4637
1911 4857
1912 4781
1913 5070
1914 5075
1915 4557
1916 4367
1917 4122
1918 4094
1919 4442
1920 5037
1921 4704
1922 4193
1923 4519
1924 4945
1925 5060
1926 5397
1927 5946
1928 5539
1929 5799
1930 5695
1931 5574
1932 5629
1933 5695
1934 5577
1935 5737
1936 5450
1937 5379
1938 5830
1939 5616
1940 5024
1941 4866
1942 4801
1943 4544
1944 4766
1945 20494
1946 53908
1947 65016
1948 70704
1949 62798
1950 85769
1951 103735
1952 108078
1953 108904
1954 105914
1955 108545
1956 107007
1957 111522
1958 109458
1959 109963
1960 112144
1961 120106
1962 125636
1963 141521
1964 162087
1965 176653
1966 179768
1967 191570
1968 207873
1969 215054
1970 218987
1971 222982
1972 227559
1973 230708
1974 234603
1975 248368
1976 251897
1977 254608
1978 263597
1979 271535
1980 272358
1981 276493
1982 288380
1983 301098
1984 309409
1985 325949
1986 339136
1987 355562
1988 372588
1989 387386
1990 393734
1991 392624
1992 395461
1993 404862
1994 415667
1995 425500
1996 436075
1997 433992
1998 452046
1999 470370
2000 507956
2001 520615
2002 539233
2003 567328
2004 611708
2005 671364
2006 720429
2007 758265
2008 807139
2009 847536
2010 911204
2011 989966
2012 1059809
2013 1116924
2014 1171252
2015 1212943
2016 1234193
2017 1252108
2018 1298614
2019 1358983
2020 1557704
2021 1693870
2022 1675824
2023 174290
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Search Results

33,970,946 results
Results by year
Filters applied: . Clear all Quoted phrases not found in phrase index: "Somatomedin Binding Protein 1", "Priority Journal"
Page 1
Insulin-like growth factors: Ligands, binding proteins, and receptors.
LeRoith D, Holly JMP, Forbes BE. LeRoith D, et al. Mol Metab. 2021 Oct;52:101245. doi: 10.1016/j.molmet.2021.101245. Epub 2021 May 4. Mol Metab. 2021. PMID: 33962049 Free PMC article. Review.
BACKGROUND: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in …
BACKGROUND: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF …
IGF research 2016-2018.
Takahashi SI. Takahashi SI. Growth Horm IGF Res. 2019 Oct-Dec;48-49:65-69. doi: 10.1016/j.ghir.2019.10.004. Epub 2019 Nov 6. Growth Horm IGF Res. 2019. PMID: 31706074 Review.
This article is based on my presentation at the 9th International Congress of the Growth Hormone Research and Insulin-like Growth Factor (IGF) Societies at Seattle, USA on 17th, September 2018. ...These areas include ligands of the IGF-I …
This article is based on my presentation at the 9th International Congress of the Growth Hormone Research and Insulin- …
Insulin-Like Growth Factor Binding Proteins--an Update.
Bach LA. Bach LA. Pediatr Endocrinol Rev. 2015 Dec;13(2):521-30. Pediatr Endocrinol Rev. 2015. PMID: 26841640 Review.
The insulin-like growth factor (IGF) system is essential for normal growth and development, and its perturbation is implicated in a number of diseases. IGF activity is finely regulated by a family of six high-affinity IGF binding …
The insulin-like growth factor (IGF) system is essential for normal growth and development, and its pertu …
What Happened to the IGF Binding Proteins?
Bach LA. Bach LA. Endocrinology. 2018 Feb 1;159(2):570-578. doi: 10.1210/en.2017-00908. Endocrinology. 2018. PMID: 29165552 Review.
Insulinlike growth factor (IGF) binding proteins (IGFBPs) 1 to 6 are high-affinity regulators of IGF activity. ...A number of mechanisms are involved, including modulation of other growth factor pathways, nuclear localizatio …
Insulinlike growth factor (IGF) binding proteins (IGFBPs) 1 to 6 are high-affinity regulators of I …
Insulin-like growth factor system in cancer: novel targeted therapies.
Brahmkhatri VP, Prasanna C, Atreya HS. Brahmkhatri VP, et al. Biomed Res Int. 2015;2015:538019. doi: 10.1155/2015/538019. Epub 2015 Mar 19. Biomed Res Int. 2015. PMID: 25866791 Free PMC article. Review.
Insulin-like growth factors (IGFs) are essential for growth and survival that suppress apoptosis and promote cell cycle progression, angiogenesis, and metastatic activities in various cancers. The IGFs actions are mediated through the IGF-1 r …
Insulin-like growth factors (IGFs) are essential for growth and survival that suppress apoptosis and promote cel …
Circulating insulin-like growth factor binding proteins in fish: Their identities and physiological regulation.
Shimizu M, Dickhoff WW. Shimizu M, et al. Gen Comp Endocrinol. 2017 Oct 1;252:150-161. doi: 10.1016/j.ygcen.2017.08.002. Epub 2017 Aug 4. Gen Comp Endocrinol. 2017. PMID: 28782538 Free article. Review.
Insulin-like growth factor binding proteins (IGFBPs) play crucial roles in regulating the availability of IGFs to receptors and prolong the half-lives of IGFs. ...They are induced under catabolic conditions such as stress and fasting but …
Insulin-like growth factor binding proteins (IGFBPs) play crucial roles in regulating the availabi …
Insulin-like growth factor binding protein: a possible marker for the metabolic syndrome?
Ruan W, Lai M. Ruan W, et al. Acta Diabetol. 2010 Mar;47(1):5-14. doi: 10.1007/s00592-009-0142-3. Epub 2009 Sep 22. Acta Diabetol. 2010. PMID: 19771387 Review.
Insulin-like growth factor (IGF) binding proteins (IGFBPs) moved on to contain both IGF high- and low-affinity binders, exerting mitogenic and metabolic actions through its complex interplay between IGF/insulin and its IGF/ …
Insulin-like growth factor (IGF) binding proteins (IGFBPs) moved on to contain both IGF high …
Insulin and insulin-like growth factor signalling in neoplasia.
Pollak M. Pollak M. Nat Rev Cancer. 2008 Dec;8(12):915-28. doi: 10.1038/nrc2536. Nat Rev Cancer. 2008. PMID: 19029956 Review.
Insulin and insulin-like growth factors (IGFs) are well known as key regulators of energy metabolism and growth. ...Epidermiological, clinical and laboratory research methods are being used to investigate novel cancer prevention and tr …
Insulin and insulin-like growth factors (IGFs) are well known as key regulators of energy metabolism and …
IGF binding proteins in cancer: mechanistic and clinical insights.
Baxter RC. Baxter RC. Nat Rev Cancer. 2014 May;14(5):329-41. doi: 10.1038/nrc3720. Epub 2014 Apr 10. Nat Rev Cancer. 2014. PMID: 24722429 Review.
The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs) were originally characterized as passive reservoirs of circulating IGFs, but they are now understood to have many actions beyond their endocrine r …
The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs) were o …
Insulin-like growth factor binding proteins in development.
Silha JV, Murphy LJ. Silha JV, et al. Adv Exp Med Biol. 2005;567:55-89. doi: 10.1007/0-387-26274-1_3. Adv Exp Med Biol. 2005. PMID: 16370136 Review.
IGFBPs regulate growth and development by regulating IGF transport to tissues and IGF bioavailability to IGF receptors at cell membrane level. IGFBP excess leads predominantly to inhibition of IGF action and growth retardation with impaired organogenesis. Abs …
IGFBPs regulate growth and development by regulating IGF transport to tissues and IGF bioavailability to IGF receptors at cell …
33,970,946 results
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