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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1975 2
1976 2
1978 2
1980 1
1981 1
1983 1
1984 2
1985 2
1986 1
1993 6
1994 98
1995 217
1996 229
1997 238
1998 283
1999 265
2000 351
2001 361
2002 341
2003 340
2004 321
2005 377
2006 339
2007 444
2008 463
2009 470
2010 429
2011 409
2012 429
2013 425
2014 465
2015 444
2016 417
2017 411
2018 395
2019 152
2020 2
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8,151 results
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Page 1
Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin.
Wang KA, et al. Nat Commun 2018. PMID 30206228 Free PMC article.
In this study, we show that for both compounds, one of the nitrogen atoms in the N-N bond originates from nitrous acid. Furthermore, we show that for both compounds, an acetylhydrazine biosynthetic synthon is generated first and then funneled via a glutamyl carrier into the respective biosynthetic pathways. ...
In this study, we show that for both compounds, one of the nitrogen atoms in the N-N bond originates from nitrous acid. Furthermore, …
II. Glutamine and glutamate
Tapiero H, et al. Biomed Pharmacother 2002 - Review. PMID 12481981
L-Glutamic acid is a ubiquitous amino acid present in many foods either in free form or in peptides and proteins. Animal protein may contain from 11 to 22% and plants protein as much as 40% glutamate by weight. The sodium salt of glutamic acid is added to several foods to enhance flavor. L-Glutamate is the most abundant free amino acid in brain and it is the major excitatory neurotransmitter of the vertebrate central nervous system. ...
L-Glutamic acid is a ubiquitous amino acid present in many foods either in free form or in peptides and proteins. Anima …
Metabolism of Dietary Glutamate in Adults.
Cynober L. Ann Nutr Metab 2018 - Review. PMID 30508813 Free article.
BACKGROUND: Glutamate is a non-essential amino acid at the crossroads of nitrogen and energy metabolism. Glutamate metabolism is characterized by reactions that may be anabolic or catabolic in nature depending on the tissue (i.e., glutamate dehydrogenase, transaminases), and it can also be either the precursor or the metabolite of glutamine. Unlike glutamine, which is the form of interorgan ammonia transport, glutamate metabolism is mostly compartmentalized within the cells, its interorgan exchanges being limited to a flux from liver to muscle. ...
BACKGROUND: Glutamate is a non-essential amino acid at the crossroads of nitrogen and energy metabolism. Glutamate metaboli
Glutamate as a neurotransmitter in the healthy brain
Zhou Y and Danbolt NC. J Neural Transm (Vienna) 2014 - Review. PMID 24578174 Free PMC article.
Glutamate is the most abundant free amino acid in the brain and is at the crossroad between multiple metabolic pathways. Considering this, it was a surprise to discover that glutamate has excitatory effects on nerve cells, and that it can excite cells to their death in a process now referred to as "excitotoxicity". ...
Glutamate is the most abundant free amino acid in the brain and is at the crossroad between multiple metabolic pathways. Considering …
Introduction to the Glutamate-Glutamine Cycle
Sonnewald U and Schousboe A. Adv Neurobiol 2016. PMID 27885624
The term 'glutamate-glutamine cycle' was coined several decades ago based on the observation that using certain (14)C-labeled precursors for studies of brain metabolism the specific radioactivity of glutamine generated from glutamate was higher than that of glutamate, its immediate precursor. ...Originally this cycle was supposed to function in a stoichiometric fashion but more recent research has seriously questioned this.This volume of Advances in Neurobiology is intended to provide a detailed discussion of recent developments in research aimed at delineating the functional roles of the cycle taking into account that in order for this system to work there must be a tight coupling between metabolism of glutamate in astrocytes, transfer of glutamine to neurons and de novo synthesis of glutamine in astrocytes. ...
The term 'glutamate-glutamine cycle' was coined several decades ago based on the observation that using certain (14)C-labeled precursors for …
The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies
Hu W, et al. Ann N Y Acad Sci 2015 - Review. PMID 25315318 Free PMC article.
Studies of the glutamate metabolic pathway have been limited, although there is some evidence that excitatory amino acid transporter-2, glutamine synthetase, and glutaminase have altered expression in schizophrenia. ...
Studies of the glutamate metabolic pathway have been limited, although there is some evidence that excitatory amino acid transporter- …
Glutamate: a truly functional amino acid.
Brosnan JT and Brosnan ME. Amino Acids 2013 - Review. PMID 22526238
Glutamate is of fundamental importance to amino acid metabolism, yet the great bulk of dietary glutamate is catabolyzed within the intestine. ...Glutamate is truly a functional amino acid....
Glutamate is of fundamental importance to amino acid metabolism, yet the great bulk of dietary glutamate is catabolyzed within …
Introduction and Summary of the 2018 Dietary Glutamate Workshop
Cynober L, et al. Ann Nutr Metab 2018. PMID 30508812 Free article.
The 2018 Dietary Glutamate Workshop was organized and sponsored by the International Glutamate Technical Committee to provide a platform for a broad expert discussion on all relevant aspects of glutamate metabolism and safety in human nutrition. ...The participants of the Workshop concluded that the present knowledge on metabolism, kinetics, developmental and general toxicity of dietary glutamates did not warrant a change in the previous ADI of "not specified."...
The 2018 Dietary Glutamate Workshop was organized and sponsored by the International Glutamate Technical Committee to provide a platform for …
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