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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1952 2
1954 1
1956 2
1959 5
1960 6
1961 9
1962 4
1965 14
1966 23
1967 15
1968 26
1969 21
1970 22
1971 22
1972 31
1973 32
1974 35
1975 26
1976 20
1977 26
1978 41
1979 47
1980 38
1981 43
1982 37
1983 53
1984 36
1985 38
1986 43
1987 47
1988 57
1989 91
1990 100
1991 70
1992 70
1993 80
1994 80
1995 94
1996 89
1997 71
1998 57
1999 59
2000 64
2001 108
2002 79
2003 117
2004 101
2005 78
2006 53
2007 60
2008 63
2009 54
2010 41
2011 46
2012 46
2013 39
2014 34
2015 38
2016 57
2017 38
2018 39
2019 23
2020 3
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2,762 results
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Page 1
New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
Bannai M and Kawai N. J Pharmacol Sci 2012 - Review. PMID 22293292 Free article.
Glycine is a non-essential amino acid that has indispensable roles in both excitatory and inhibitory neurotransmission via N-methyl-D-aspartate type glutamate receptors and glycine receptors, respectively. ...Pharmacological studies investigating the mechanisms of glycine on sleep were also performed. In this review, we will describe both our recent findings regarding how and where orally administered glycine acts and findings from our rat study and human trials....
Glycine is a non-essential amino acid that has indispensable roles in both excitatory and inhibitory neurotransmission via N-methyl-D
Glycine Induces Migration of Microglial BV-2 Cells via SNAT-Mediated Cell Swelling.
Kittl M, et al. Cell Physiol Biochem 2018. PMID 30359963 Free article.
During phagocytosis, glycine contributes to (local) cell volume-dependent processes like lamellipodium formation. Similar to the expansion of the lamellipodium we assume that glycine also affects the migration of microglial cells in a cell volume-dependent manner. ...The cell membrane potential (Vmem) displayed a distinctive time course after glycine application; initially, glycine evoked a rapid depolarization mediated by Na+-coupled glycine uptake via SNAT, followed by a further gradual depolarization, which was fully suppressed by DCPIB. ...
During phagocytosis, glycine contributes to (local) cell volume-dependent processes like lamellipodium formation. Similar to the expa …
Glycine treatment enhances developmental potential of porcine oocytes and early embryos by inhibiting apoptosis.
Li S, et al. J Anim Sci 2018. PMID 29762687 Free PMC article.
Our studies found that treatment with glycine in IVM culture medium increased nuclear maturation rate, but varying the concentrations of glycine (0.6, 6, or 12 mM) had no significant effect. ...All the glycine treatment groups had decreased levels of ROS in both matured oocytes and at the 2-cell stage (P < 0.05). At the 2-cell stage, the 6 mM glycine group had ROS levels that were lesser than the other 2 glycine treatment groups (0.6 and 12 mM). ...
Our studies found that treatment with glycine in IVM culture medium increased nuclear maturation rate, but varying the concentrations …
Glycine improves the remodeling process of tenocytes in vitro.
Vieira CP, et al. Cell Biol Int 2018. PMID 29345399
In vivo, glycine, component of the typical Gly-X-Y collagen tripeptide, showed beneficial effects in biochemical and biomechanical properties of Achilles tendon with tendinitis. In this study, we analyzed the effect of glycine in tenocytes subjected to inflammation. Tenocytes from Achilles tendon of rats were treated with TNF-α (10 ng/mL) with and without previous treatment with glycine (20 mM). ...
In vivo, glycine, component of the typical Gly-X-Y collagen tripeptide, showed beneficial effects in biochemical and biomechanical pr …
Glycine 1.5% for irrigation should be abandoned.
Hahn RG. Urol Int 2013 - Review. PMID 24051511 Free article.
With only one exception, which is probably due to low power, these studies either show a poorer outcome after administration or absorption of glycine solution or else that glycine 2.2% is more toxic than glycine 1.5%. ...The author argues that glycine 1.5% should be abandoned completely....
With only one exception, which is probably due to low power, these studies either show a poorer outcome after administration or absorption o …
Glycine: a new anti-inflammatory immunonutrient.
Wheeler MD, et al. Cell Mol Life Sci 1999 - Review. PMID 11212343
Glycine has been well characterized in spinal cord as an inhibitory neurotransmitter which activates a glycine-gated chloride channel (GlyR) expressed in postsynaptic membranes. ...Pharmacological analysis using a GlyR antagonist strychnine, chloride-free buffer, and radiolabeled chloride has provided convincing evidence to support the hypothesis that many white blood cells contain a glycine-gated chloride channel with properties similar to the spinal cord GlyR. ...
Glycine has been well characterized in spinal cord as an inhibitory neurotransmitter which activates a glycine-gated chloride
Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance.
El-Hafidi M, et al. Oxid Med Cell Longev 2018. PMID 29675131 Free PMC article.
Our hypothesis is that the correction of glutathione levels by glycine treatment leads to reduced oxidative stress, a mechanism associated with improved insulin signaling and IR. ...Thus, supplementing diets with glycine to correct GSH deficiency and to reduce oxidative stress provides significant metabolic benefits to SF rats by improving insulin sensitivity....
Our hypothesis is that the correction of glutathione levels by glycine treatment leads to reduced oxidative stress, a mechanism assoc …
Is glycine effective against elevated blood pressure?
El Hafidi M, et al. Curr Opin Clin Nutr Metab Care 2006 - Review. PMID 16444815
RECENT FINDINGS: The addition of glycine to the diet reduces high blood pressure in a rat model of the metabolic syndrome. Also, glycine supplemented to the low protein diet of rat dams during pregnancy has a beneficial effect on blood pressure in their offspring. ...On the other hand, more studies are needed to explore the beneficial effect of glycine in other models of hypertension and to investigate possible side-effects of treatment with glycine....
RECENT FINDINGS: The addition of glycine to the diet reduces high blood pressure in a rat model of the metabolic syndrome. Also, g
Structure, function and regulation of glycine neurotransporters.
Aragón C and López-Corcuera B. Eur J Pharmacol 2003 - Review. PMID 14612155
The synaptic action of glycine ends by active recapture through sodium- and chloride-coupled glycine transporters located in glial and neuronal plasma membranes, whose structure-function relationship is being studied. ...This review deals on recent progress on localization, transport mechanisms, structure, regulation and pharmacology of the glycine transporters (GLYTs)....
The synaptic action of glycine ends by active recapture through sodium- and chloride-coupled glycine transporters located in g …
Effectivity of air-abrasive powder based on glycine and tricalcium phosphate in removal of initial biofilm on titanium and zirconium oxide surfaces in an ex vivo model.
John G, et al. Clin Oral Investig 2016. PMID 26319979
RESULTS: Within the titanium groups, mean RPA was determined in the following descending order: sodium bicarbonate > glycine > glycine + tricalcium phosphate. ...Especially on zirconium surfaces, decontamination with glycine + tricalcium phosphate seemed to be more efficient than treatment with glycine or sodium bicarbonate. ...
RESULTS: Within the titanium groups, mean RPA was determined in the following descending order: sodium bicarbonate > glycine > …
2,762 results
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