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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 8
1946 16
1947 17
1948 24
1949 26
1950 23
1951 42
1952 36
1953 39
1954 40
1955 30
1956 51
1957 52
1958 69
1959 66
1960 70
1961 73
1962 74
1963 88
1964 165
1965 185
1966 156
1967 144
1968 174
1969 132
1970 115
1971 97
1972 125
1973 116
1974 97
1975 127
1976 120
1977 99
1978 112
1979 89
1980 83
1981 109
1982 102
1983 92
1984 101
1985 100
1986 78
1987 103
1988 91
1989 86
1990 98
1991 69
1992 96
1993 72
1994 75
1995 82
1996 58
1997 83
1998 65
1999 60
2000 60
2001 58
2002 71
2003 63
2004 61
2005 78
2006 96
2007 110
2008 109
2009 95
2010 117
2011 143
2012 183
2013 223
2014 249
2015 303
2016 298
2017 301
2018 341
2019 167
2020 6
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7,387 results
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Page 1
Mini-review on glycolysis and cancer.
Akram M. J Cancer Educ 2013 - Review. PMID 23728993
Glycolysis is a universal pathway in the living cells. The complete pathway of glycolysis was elucidated in 1940. This pathway is often referred to as Embden-Meyerhof pathway in honor of the two biochemists that made a major contribution to the knowledge of glycolysis. ...Inhibition of glycolysis in cancer cells is a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. ...
Glycolysis is a universal pathway in the living cells. The complete pathway of glycolysis was elucidated in 1940. This pathway
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Lunt SY and Vander Heiden MG. Annu Rev Cell Dev Biol 2011 - Review. PMID 21985671
Warburg's observation that cancer cells exhibit a high rate of glycolysis even in the presence of oxygen (aerobic glycolysis) sparked debate over the role of glycolysis in normal and cancer cells. Although it has been established that defects in mitochondrial respiration are not the cause of cancer or aerobic glycolysis, the advantages of enhanced glycolysis in cancer remain controversial. ...
Warburg's observation that cancer cells exhibit a high rate of glycolysis even in the presence of oxygen (aerobic glycolysis) …
Tumor glycolysis as a target for cancer therapy: progress and prospects.
Ganapathy-Kanniappan S and Geschwind JF. Mol Cancer 2013 - Review. PMID 24298908 Free PMC article.
Under hypoxic conditions where glycolysis remains the predominant energy producing pathway sensitizing cancer cells would require intracellular depletion of ATP by inhibition of glycolysis. Together, the oncogenic regulation of glycolysis and multifaceted roles of glycolytic components underscore the biological significance of tumor glycolysis. ...
Under hypoxic conditions where glycolysis remains the predominant energy producing pathway sensitizing cancer cells would require int …
Glycolysis Inhibitors for Anticancer Therapy: A Review of Recent Patents.
Sheng H and Tang W. Recent Pat Anticancer Drug Discov 2016 - Review. PMID 27087655
BACKGROUND: The aerobic glycolysis in tumor cells known as Warburg effect is one of the most important hallmarks of cancer. It is proposed that the upregulation of the series of metabolic enzymes along the glycolytic pathway may contribute to the Warburg effect. ...This review summaries recent patents in the development of small molecule inhibitors for the key enzymes in tumor glycolysis. ...
BACKGROUND: The aerobic glycolysis in tumor cells known as Warburg effect is one of the most important hallmarks of cancer. It is pro …
Oxidative phosphorylation versus glycolysis: what fuel do spermatozoa use?
du Plessis SS, et al. Asian J Androl 2015 - Review. PMID 25475660 Free PMC article.
It is produced in the mitochondria through OXPHOS as well as in the head and principal piece of the flagellum through glycolysis. ...Mitochondrial respiration is considered to be a more efficient metabolic process for ATP synthesis in comparison to glycolysis. ...
It is produced in the mitochondria through OXPHOS as well as in the head and principal piece of the flagellum through glycolysis. ... …
Lactic Acid: No Longer an Inert and End-Product of Glycolysis.
Sun S, et al. Physiology (Bethesda) 2017 - Review. PMID 29021365 Free article.
For decades, lactic acid has been considered a dead-end product of glycolysis. Research in the last 20+ years has shown otherwise. ...
For decades, lactic acid has been considered a dead-end product of glycolysis. Research in the last 20+ years has shown otherwise. .. …
Glycolysis inhibition as a cancer treatment and its role in an anti-tumour immune response.
Gill KS, et al. Biochim Biophys Acta 2016 - Review. PMID 27373814
Increased glycolysis is the main source of energy supply in cancer cells that use this metabolic pathway for ATP generation. ...In this review we look at the glycolysis pathway as a target for cancer treatments. We also examine the interplay between the glycolysis modulation and the immune response as an anti-cancer therapy....
Increased glycolysis is the main source of energy supply in cancer cells that use this metabolic pathway for ATP generation. ...In th …
Glycolysis inhibition for anticancer treatment.
Pelicano H, et al. Oncogene 2006 - Review. PMID 16892078
Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation of ATP as a main source of their energy supply. ...Importantly, the increased dependence of cancer cells on glycolytic pathway for ATP generation provides a biochemical basis for the design of therapeutic strategies to preferentially kill cancer cells by pharmacological inhibition of glycolysis. ...
Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation of ATP as a main source of their energy …
Warburg effect or reverse Warburg effect? A review of cancer metabolism
Xu XD, et al. Oncol Res Treat 2015 - Review. PMID 25792083
In the 1920s, Warburg found that cancer cells prefer to produce adenosine triphosphate (ATP) by glycolysis, which is a less efficient pathway compared to oxidative phosphorylation. ...Some studies have now shown contradicting evidence and a new hypothesis, the reverse Warburg effect, has been put forward, in which cancer cells produce most of their ATP via glycolysis, even under aerobic conditions. ...
In the 1920s, Warburg found that cancer cells prefer to produce adenosine triphosphate (ATP) by glycolysis, which is a less efficient …
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