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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2005 2
2006 4
2007 6
2008 1
2009 2
2010 2
2011 3
2012 3
2013 3
2014 9
2015 6
2016 8
2017 5
2018 3
2019 1
2020 1
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51 results
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Page 1
CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.
Smoum R, Baraghithy S, Chourasia M, Breuer A, Mussai N, Attar-Namdar M, Kogan NM, Raphael B, Bolognini D, Cascio MG, Marini P, Pertwee RG, Shurki A, Mechoulam R, Bab I. Smoum R, et al. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8774-9. doi: 10.1073/pnas.1503395112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124120 Free PMC article.
Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, de Petrocellis L, Ullmer C, Rothenhäusler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, de Vries H, Mastrangelo N, Xia L, Alachouzos G, Baggelaar MP, Martella A, Mock ED, Deng H, Heitman LH, Connor M, Di Marzo V, Gertsch J, Lichtman AH, Maccarrone M, Pacher P, Glass M, van der Stelt M. Soethoudt M, et al. Nat Commun. 2017 Jan 3;8:13958. doi: 10.1038/ncomms13958. Nat Commun. 2017. PMID: 28045021 Free PMC article.
HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
Hanus L, Breuer A, Tchilibon S, Shiloah S, Goldenberg D, Horowitz M, Pertwee RG, Ross RA, Mechoulam R, Fride E. Hanus L, et al. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14228-33. doi: 10.1073/pnas.96.25.14228. Proc Natl Acad Sci U S A. 1999. PMID: 10588688 Free PMC article.
Inflammation and CB2 signaling drive novel changes in the ocular lipidome and regulate immune cell activity in the eye.
Toguri JT, Leishman E, Szczesniak AM, Laprairie RB, Oehler O, Straiker AJ, Kelly MEM, Bradshaw HB. Toguri JT, et al. Prostaglandins Other Lipid Mediat. 2018 Nov;139:54-62. doi: 10.1016/j.prostaglandins.2018.09.004. Epub 2018 Sep 16. Prostaglandins Other Lipid Mediat. 2018. PMID: 30232034
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