Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2005 1
2008 1
2009 1
2010 2
2011 1
2013 4
2015 2
2016 2
2017 3
2018 1
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

14 results
Results by year
Filters applied: . Clear all
Page 1
Lateral habenula in the pathophysiology of depression.
Yang Y, et al. Curr Opin Neurobiol 2018 - Review. PMID 29175713 Free article.
Recently, the lateral habenula (LHb) has emerged as a key brain region in the pathophysiology of depression. Increasing evidence from rodent, non-human primate and human studies indicates that the aberrant activity of the LHb is associated with depressive symptoms such as helplessness, anhedonia, and excessive negative focus. ...
Recently, the lateral habenula (LHb) has emerged as a key brain region in the pathophysiology of depression. Increasing evidence from …
The habenula as a critical node in chronic stress-related anxiety.
Jacinto LR, et al. Exp Neurol 2017. PMID 27940019
The habenula is activated in response to stressful and aversive events, resulting in exploratory inhibition. Although possible mechanisms for habenula activation have been proposed, the effects of chronic stress on the habenular structure have never been studied. ...This study highlights the role of the habenula in the stress responses and how its sub-regions are structurally impacted by chronic stress with physiological and behavioral consequences....
The habenula is activated in response to stressful and aversive events, resulting in exploratory inhibition. Although possible mechan …
Selectively Impaired Endocannabinoid-Dependent Long-Term Depression in the Lateral Habenula in an Animal Model of Depression.
Park H, et al. Cell Rep 2017. PMID 28700932 Free article.
Abnormal potentiation in the lateral habenula (LHb) has been suggested to mediate depression-like behaviors. However, the underlying mechanisms of the synaptic efficacy regulation of LHb synapses and the potential for their modulation are only poorly understood. ...
Abnormal potentiation in the lateral habenula (LHb) has been suggested to mediate depression-like behaviors. However, the underlying …
Volumetric MRI study of the habenula in first episode, recurrent and chronic major depression.
Carceller-Sindreu M, et al. Eur Neuropsychopharmacol 2015. PMID 26404405
The habenula (Hb) can play an important role in major depressive disorder (MDD) as it is a key node between fronto-limbic areas and midbrain monoaminergic structures. ...
The habenula (Hb) can play an important role in major depressive disorder (MDD) as it is a key node between fronto-limbic areas and m …
Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study.
Savitz JB, et al. Biol Psychiatry 2011. PMID 21094939 Free PMC article.
BACKGROUND: Increased activity of the habenula has been implicated in the etiology of major depressive disorder (MDD), in which reductions in habenula volume are present after death. ...A reduction in habenula volume might thus have functional consequences that contribute to the risk for developing affective disease....
BACKGROUND: Increased activity of the habenula has been implicated in the etiology of major depressive disorder (MDD), in which reduc …
Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats
Brown PL and Shepard PD. PLoS One 2013. PMID 23593280 Free PMC article.
High-intensity footshock (120, 0.8 mA shocks over 40 min) also elevates cFos expression in the rostromedial tegmental area, medial and lateral aspects of the lateral habenula and the paraventricular thalamus. ...These data confirm the involvement of the lateral habenula in modulating the activity of rostromedial tegmental area neurons in response to mild aversive stimuli and suggest that dopamine input may contribute to footshock- induced activation of cFos expression in the lateral habenula....
High-intensity footshock (120, 0.8 mA shocks over 40 min) also elevates cFos expression in the rostromedial tegmental area, medial and later …
Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia
Ranft K, et al. Psychol Med 2010. PMID 19671211
RESULTS: Significantly reduced habenular volumes of the medial and lateral habenula were estimated in depressive patients in comparison to normal controls and schizophrenia patients. ...
RESULTS: Significantly reduced habenular volumes of the medial and lateral habenula were estimated in depressive patients in comparis …
14 results
Jump to page
Feedback