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An intranasal adjuvanted, recombinant influenza A/H5 vaccine candidate induces broad priming against diverse influenza A/H5N1 virus clades in a phase I randomized trial in healthy adults.
Deming ME, Toapanta FR, Pasetti M, Golding H, Khurana S, Hamouda T, Fattom A, Liang Y, Tennant SM, McGilvray MF, Bernal PJ, Oshinsky JJ, Datta S, Booth JP, Coughlan L, Neuzil KM, Costley CD, Kotloff KL, Sztein MB, Ortiz JR. Deming ME, et al. Among authors: hamouda t. Res Sq [Preprint]. 2025 Mar 5:rs.3.rs-6059149. doi: 10.21203/rs.3.rs-6059149/v1. Res Sq. 2025. Update in: Nat Commun. 2025 Nov 6;16(1):9321. doi: 10.1038/s41467-025-64686-3. PMID: 40092447 Free PMC article. Updated. Preprint.
An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial.
Deming ME, Toapanta FR, Pasetti M, Golding H, Khurana S, Hamouda T, Fattom A, Liang Y, Tennant SM, McGilvray MF, Bernal PJ, Oshinsky JJ, Datta S, Booth JP, Coughlan L, Neuzil KM, Costley CD, Kotloff KL, Sztein MB, Ortiz JR; rH5 Writing Group. Deming ME, et al. Among authors: hamouda t. Nat Commun. 2025 Nov 6;16(1):9321. doi: 10.1038/s41467-025-64686-3. Nat Commun. 2025. PMID: 41198655 Free PMC article. Clinical Trial.
37 results