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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1954 4
1955 18
1956 32
1957 44
1958 49
1959 68
1960 68
1961 79
1962 80
1963 74
1964 101
1965 272
1966 273
1967 348
1968 350
1969 457
1970 423
1971 498
1972 480
1973 549
1974 574
1975 463
1976 441
1977 442
1978 375
1979 423
1980 466
1981 493
1982 529
1983 552
1984 633
1985 648
1986 642
1987 684
1988 689
1989 842
1990 1041
1991 1096
1992 1227
1993 1354
1994 1526
1995 1590
1996 1734
1997 1844
1998 1966
1999 2122
2000 2169
2001 2388
2002 2555
2003 2727
2004 2995
2005 3039
2006 3507
2007 3662
2008 3605
2009 3972
2010 4157
2011 4397
2012 4798
2013 5002
2014 4975
2015 5005
2016 4653
2017 4512
2018 4459
2019 2269
2020 39
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96,164 results
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Page 1
Development of multicellular spheroids of HeLa cells cocultured with fibroblasts and their response to X-irradiation.
Sasaki T, et al. Cancer Res 1984. PMID 6690045 Free article.
HeLa cells cocultured with human diploid fibroblasts developed a more stable and tightly packed spheroid than did HeLa cells alone. ...The rate of cell loss from spheroid surface, expressed as cells lost per sq mm of spheroid surface per hr, was twice as high for spheroids of HeLa cells alone as for cocultured spheroids. ...
HeLa cells cocultured with human diploid fibroblasts developed a more stable and tightly packed spheroid than did HeLa
Proteomic investigation into betulinic acid-induced apoptosis of human cervical cancer HeLa cells.
Xu T, et al. PLoS One 2014. PMID 25148076 Free PMC article.
The apoptotic process was further investigated using a proteomics approach to reveal protein expression changes in HeLa cells following betulinic acid treatment. ...These results suggest that betulinic acid induces apoptosis of HeLa cells by triggering both the endoplasmic reticulum pathway and the ROS-mediated mitochondrial pathway....
The apoptotic process was further investigated using a proteomics approach to reveal protein expression changes in HeLa cells
Involvement of protein kinase C in phorbol ester-induced sensitization of HeLa cells to cis-diamminedichloroplatinum(II).
Basu A, et al. J Biol Chem 1990. PMID 2341390 Free article.
The maximum stimulation of protein kinase C (6-fold) was observed with 10 nM TPA. 4 alpha-Phorbol 12,13-didecanoate neither activated protein kinase C nor sensitized HeLa cells to CP. 4-O-Methyl-TPA, which does not affect cell cycle distribution of HeLa cells, also sensitized these cells to CP by 6-fold and activated protein kinase C by 3-fold. Inhibitors of protein kinase C, such as palmitoylcarnitine and sphingosine, antagonized PDBu-induced sensitization of HeLa cells to CP. ...
The maximum stimulation of protein kinase C (6-fold) was observed with 10 nM TPA. 4 alpha-Phorbol 12,13-didecanoate neither activated protei …
HeLa cells form focal contacts that are not fibronectin dependent.
Morgan J and Garrod D. J Cell Sci 1984. PMID 6746753 Free article.
HeLa cells cultured on glass substrata produce numerous prominent focal contacts, which reside at the termini of actin microfilament bundles. However, very few of the cells stain for fibronectin with specific anti-fibronectin antibody. Moreover, the cells form focal contacts in fibronectin-depleted medium, in the presence of high concentrations of anti-fibronectin immunoglobulin G and in the presence of monensin. ...
HeLa cells cultured on glass substrata produce numerous prominent focal contacts, which reside at the termini of actin microfi
Paraquat-resistant HeLa cells: increased cellular content of glutathione peroxidase.
Krall J, et al. Arch Biochem Biophys 1991. PMID 1897959
Paraquat-resistant HeLa cells were selected and characterized to determine the mechanism(s) of the toxic action of paraquat for cultured mammalian cells. From HeLa cells already selected for resistance to the toxicity of 40 microM paraquat more resistant cells were selected in 90 microM paraquat. ...
Paraquat-resistant HeLa cells were selected and characterized to determine the mechanism(s) of the toxic action of paraquat fo …
Electrical effects on the proliferation of living HeLa cells cultured on optically transparent electrode surface.
Yaoita M, et al. J Biotechnol 1990. PMID 1366909
At the boundary potential range between +0.5 V to +0.7 V, where HeLa cells were cultured on the potential-controlled optically transparent In2O3 electrode (OTE) surface, intriguing effects on HeLa cells appeared. At this potential range, where HeLa cells cultured on a potential-applied OTE, all the cells were alive accompanying morphological change. ...
At the boundary potential range between +0.5 V to +0.7 V, where HeLa cells were cultured on the potential-controlled optically …
The biotin requirement of HeLa cells.
Dakshinamurti K and Chalifour LE. J Cell Physiol 1981. PMID 7251693
HeLa cells are able to internalize avidin-bound biotin. Biotin is released from this complex to function as the prosthetic group of biotin enzymes. HeLa cells do have a nutritional requirement for biotin....
HeLa cells are able to internalize avidin-bound biotin. Biotin is released from this complex to function as the prosthetic gro
Sodium butyrate blocks HeLa cells preferentially in early G1 phase of the cell cycle.
Xue S and Rao PN. J Cell Sci 1981. PMID 7320081 Free article.
The effects of sodium butyrate on the cell-cycle transverse of HeLa cells was re-examined using the kinetic and the premature chromosome condensation methods of cell-cycle analysis. ...Cells in the early G1 period are the most sensitive to the inhibitory effects of the drug. When HeLa cells in exponential growth were exposed to a 5 mM concentration of butyrate for 48 h. 67% of the cell population was preferentially arrested in the early G1 period as indicated by the condensed morphology of the prematurely condensed chromosomes (PCC). ...
The effects of sodium butyrate on the cell-cycle transverse of HeLa cells was re-examined using the kinetic and the premature …
The invasion of tobacco mosaic virus RNA induces endoplasmic reticulum stress-related autophagy in HeLa cells.
Li L, et al. Biosci Rep 2012. PMID 21729006 Free PMC article.
To model such an alien virus invasion, we chose TMV (tobacco mosaic virus) and used human epithelial carcinoma cells (HeLa cells) as its 'fresh' host. ...Taken together, our data indicate that HeLa cells used ERS and ERS-related autophagy to defend against TMV-RNA....
To model such an alien virus invasion, we chose TMV (tobacco mosaic virus) and used human epithelial carcinoma cells (HeLa
Changes in the relative proportion of transformation-sensitive polypeptides in giant HeLa cells produced by irradiation with lethal doses of x-rays.
Bellatin J, et al. Proc Natl Acad Sci U S A 1982. PMID 6956866 Free PMC article.
Irradiation of HeLa cells with 1,100 rads (1 rad = 0.01 J/kg = 0.01 Gy) of x-rays yielded a pure population of giant cells 5-7 days after irradiation. ...These polypeptides also have been identified in HeLa cells and other transformed human cells such as Detroit 98, Chang liver, Fl-amnion, and WISH-amnion [Bravo, R. & Celis, J. (1982) Clin. ...
Irradiation of HeLa cells with 1,100 rads (1 rad = 0.01 J/kg = 0.01 Gy) of x-rays yielded a pure population of giant cells
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