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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1961 1
1967 1
1989 7
1990 16
1991 20
1992 21
1993 4
1994 17
1995 10
1996 12
1997 19
1998 14
1999 16
2000 18
2001 16
2002 12
2003 14
2004 14
2005 24
2006 23
2007 19
2008 19
2009 23
2010 16
2011 27
2012 20
2013 22
2014 24
2015 24
2016 16
2017 13
2018 22
2019 2
2020 0
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487 results
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Page 1
Hemolysis and immune regulation.
Zhong H and Yazdanbakhsh K. Curr Opin Hematol 2018 - Review. PMID 29461260 Free PMC article.
Recent studies which will be reviewed here have uncovered several novel mechanisms by which hemolysis can alter immunological functions and increase the risk of severe complications in hemolytic disorders. ...SUMMARY: Hemolysis breakdown products show remarkable effects on the regulation of immune cell differentiation and function....
Recent studies which will be reviewed here have uncovered several novel mechanisms by which hemolysis can alter immunological functio …
Warm autoimmune hemolytic anemia
Naik R. Hematol Oncol Clin North Am 2015 - Review. PMID 26043384
The pathophysiology of disease involves phagocytosis of autoantibody-coated RBCs in the spleen and complement-mediated hemolysis. ...
The pathophysiology of disease involves phagocytosis of autoantibody-coated RBCs in the spleen and complement-mediated hemolysis. ...
Pathogenesis and mechanisms of antibody-mediated hemolysis.
Flegel WA. Transfusion 2015 - Review. PMID 26174897 Free PMC article.
Several mechanisms of antibody-mediated hemolysis are well understood. Such hemolysis after transfusion is reliably avoided in a donor-recipient pair, if one individual is negative for the cognate antigen to which the other has the antibody. STUDY DESIGN AND RESULTS: Mechanisms of antibody-mediated hemolysis were reviewed based on a presentation at the Strategies to Address Hemolytic Complications of Immune Globulin Infusions Workshop addressing intravenous immunoglobulin (IVIG) and ABO antibodies. ...
Several mechanisms of antibody-mediated hemolysis are well understood. Such hemolysis after transfusion is reliably avoided in …
Cold agglutinin-mediated autoimmune hemolytic anemia
Berentsen S, et al. Hematol Oncol Clin North Am 2015 - Review. PMID 26043385
Hemolysis in CAD and CAS is mediated by the classical complement pathway and is predominantly extravascular. Not all patients require treatment. ...
Hemolysis in CAD and CAS is mediated by the classical complement pathway and is predominantly extravascular. Not all patients require
Direct antiglobulin ("Coombs") test-negative autoimmune hemolytic anemia: a review
Segel GB and Lichtman MA. Blood Cells Mol Dis 2014 - Review. PMID 24411920
In cases in which the phenotype is compatible with warm-antibody type, autoimmune hemolytic anemia and the direct antiglobulin test is negative, an alternative method to detect low levels of IgG sensitization, use of 4°C, low ionic strength washes to prepare the cells for the direct antiglobulin test reaction to permit retention and identification of low affinity IgG antibodies, and, if the latter are uninformative, testing for sensitization with an anti-IgA, and, if necessary, an anti-IgM reagent identifies cases of warm-antibody type, immune hemolysis not verified by a commercial reagent....
In cases in which the phenotype is compatible with warm-antibody type, autoimmune hemolytic anemia and the direct antiglobulin test is negat …
Hemolysis from ABO Incompatibility.
Simmons DP and Savage WJ. Hematol Oncol Clin North Am 2015 - Review. PMID 26043383
In addition to transfusion, ABO incompatibility can cause hemolysis in hematopoietic and solid organ transplantation, hemolytic disease of the newborn, and intravenous immunoglobulin infusion. ...
In addition to transfusion, ABO incompatibility can cause hemolysis in hematopoietic and solid organ transplantation, hemolytic disea …
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, et al. Nat Immunol 2016. PMID 27798618
Hemolysis drives susceptibility to bacterial infections and predicts poor outcome from sepsis. These detrimental effects are commonly considered to be a consequence of heme-iron serving as a nutrient for bacteria. ...
Hemolysis drives susceptibility to bacterial infections and predicts poor outcome from sepsis. These detrimental effects are commonly
Antibody Inhibition of Properdin Prevents Complement-Mediated Intravascular and Extravascular Hemolysis.
Gullipalli D, et al. J Immunol 2018. PMID 29898960 Free PMC article.
In this study, we show that function-blocking anti-properdin (P) mAbs dose-dependently inhibited autologous, complement-mediated hemolysis induced by factor H dysfunction. Furthermore, anti-human P (hP) mAbs potently and dose-dependently inhibited acidified serum-induced hemolysis of PNH erythrocytes (Ham test). ...
In this study, we show that function-blocking anti-properdin (P) mAbs dose-dependently inhibited autologous, complement-mediated hemolysi
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