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2002 5
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2005 5
2006 6
2007 6
2008 2
2009 6
2010 5
2011 6
2012 5
2013 10
2014 14
2015 7
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Page 1
Targeting KIT With Antibody-Drug Conjugates in Chromophobe Renal Cell Carcinoma.
Alchoueiry M, Mansour H, Khabibullin D, Han T, Chaturantabut S, Bzeih W, Tang Y, Williams JF, Hirsch MS, Priolo C, Sellers WR, Henske EP. Alchoueiry M, et al. Among authors: henske ep. Clin Genitourin Cancer. 2025 Apr 15;23(4):102359. doi: 10.1016/j.clgc.2025.102359. Online ahead of print. Clin Genitourin Cancer. 2025. PMID: 40408838
Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.
Kalvala AK, Silwal A, Patel B, Kasetti A, Shetty K, Cho JH, Lara G, Daugherity B, Diesler R, Pooladanda V, Rueda BR, Henske EP, Yu JJ, Markiewski M, Karbowniczek M. Kalvala AK, et al. Among authors: henske ep. bioRxiv [Preprint]. 2024 Sep 10:2024.09.09.611297. doi: 10.1101/2024.09.09.611297. bioRxiv. 2024. PMID: 39314494 Free PMC article. Preprint.
Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group.
Mekahli D, Müller RU, Marlais M, Wlodkowski T, Haeberle S, de Argumedo ML, Bergmann C, Breysem L, Fladrowski C, Henske EP, Janssens P, Jouret F, Kingswood JC, Lattouf JB, Lilien M, Maleux G, Rozenberg M, Siemer S, Devuyst O, Schaefer F, Kwiatkowski DJ, Rouvière O, Bissler J. Mekahli D, et al. Among authors: henske ep. Nat Rev Nephrol. 2024 Jun;20(6):402-420. doi: 10.1038/s41581-024-00818-0. Epub 2024 Mar 5. Nat Rev Nephrol. 2024. PMID: 38443710 Review.
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Liu W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG; Cancer Genome Atlas Research Network; Spellman PT, Rathmell WK, Linehan WM. Ricketts CJ, et al. Among authors: henske ep. Cell Rep. 2024 Apr 23;43(4):113063. doi: 10.1016/j.celrep.2023.113063. Epub 2024 Apr 4. Cell Rep. 2024. PMID: 38578829 Free article. No abstract available.
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Alesi N, Khabibullin D, Rosenthal DM, Akl EW, Cory PM, Alchoueiry M, Salem S, Daou M, Gibbons WF, Chen JA, Zhang L, Filippakis H, Graciotti L, Miceli C, Monfregola J, Vilardo C, Morroni M, Di Malta C, Napolitano G, Ballabio A, Henske EP. Alesi N, et al. Among authors: henske ep. Nat Commun. 2024 Jan 9;15(1):406. doi: 10.1038/s41467-023-44229-4. Nat Commun. 2024. PMID: 38195686 Free PMC article.
Chromophobe renal cell carcinoma.
Henske EP, Cheng L, Hakimi AA, Choueiri TK, Braun DA. Henske EP, et al. Cancer Cell. 2023 Aug 14;41(8):1383-1388. doi: 10.1016/j.ccell.2023.07.006. Epub 2023 Aug 3. Cancer Cell. 2023. PMID: 37541245 Free article.
Lymphangioleiomyomatosis: circulating levels of FGF23 and pulmonary diffusion.
Esposito AJ, Imani J, Shrestha S, Bagwe S, Lamattina AM, Vivero M, Goldberg HJ, Rosas IO, Henske EP, El-Chemaly SY. Esposito AJ, et al. Among authors: henske ep. J Bras Pneumol. 2023 May 1;49(2):e20220356. doi: 10.36416/1806-3756/e20220356. eCollection 2023. J Bras Pneumol. 2023. PMID: 37132737 Free PMC article.
Lymphangioleiomyomatosis (LAM) Cell Atlas.
Du Y, Guo M, Wu Y, Wagner A, Perl AK, Wikenheiser-Brokamp K, Yu J, Gupta N, Kopras E, Krymskaya V, Obraztsova K, Tang Y, Kwiatkowski D, Henske EP, McCormack F, Xu Y. Du Y, et al. Among authors: henske ep. Thorax. 2023 Jan;78(1):85-87. doi: 10.1136/thoraxjnl-2022-218772. Epub 2022 Sep 7. Thorax. 2023. PMID: 36599466 Free PMC article.
Keeping up with the Rag GTPases.
Alesi N, Henske EP. Alesi N, et al. Among authors: henske ep. Nat Cell Biol. 2022 Sep;24(9):1330-1331. doi: 10.1038/s41556-022-00981-1. Nat Cell Biol. 2022. PMID: 36097073 No abstract available.
Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.
Zhang L, Hobeika CS, Khabibullin D, Yu D, Filippakis H, Alchoueiry M, Tang Y, Lam HC, Tsvetkov P, Georgiou G, Lamb C, Stone E, Puigserver P, Priolo C, Henske EP. Zhang L, et al. Among authors: henske ep. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2122840119. doi: 10.1073/pnas.2122840119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867762 Free PMC article.
ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells.
Shrestha S, Lamattina A, Pacheco-Rodriguez G, Ng J, Liu X, Sonawane A, Imani J, Qiu W, Kosmas K, Louis P, Hentschel A, Steagall WK, Onishi R, Christou H, Henske EP, Glass K, Perrella MA, Moss J, Tantisira K, El-Chemaly S. Shrestha S, et al. Among authors: henske ep. Life Sci Alliance. 2022 Feb 18;5(5):e202201369. doi: 10.26508/lsa.202201369. Print 2022 May. Life Sci Alliance. 2022. PMID: 35181635 Free PMC article.
Modeling tuberous sclerosis with organoids.
Ihrie RA, Henske EP. Ihrie RA, et al. Among authors: henske ep. Science. 2022 Jan 28;375(6579):382-383. doi: 10.1126/science.abn6158. Epub 2022 Jan 27. Science. 2022. PMID: 35084978
Seventh BHD international symposium: recent scientific and clinical advancement.
Woodford MR, Andreou A, Baba M, van de Beek I, Di Malta C, Glykofridis I, Grimes H, Henske EP, Iliopoulos O, Kurihara M, Lazor R, Linehan WM, Matsumoto K, Marciniak SJ, Namba Y, Pause A, Rajan N, Ray A, Schmidt LS, Shi W, Steinlein OK, Thierauf J, Zoncu R, Webb A, Mollapour M. Woodford MR, et al. Among authors: henske ep. Oncotarget. 2022 Jan 20;13:173-181. doi: 10.18632/oncotarget.28176. eCollection 2022. Oncotarget. 2022. PMID: 35070081 Free PMC article.
A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo.
Hernandez JOR, Wang X, Vazquez-Segoviano M, Lopez-Marfil M, Sobral-Reyes MF, Moran-Horowich A, Sundberg M, Lopez-Cantu DO, Probst CK, Ruiz-Esparza GU, Giannikou K, Abdi R, Henske EP, Kwiatkowski DJ, Sahin M, Lemos DR. Hernandez JOR, et al. Among authors: henske ep. Nat Commun. 2021 Nov 11;12(1):6496. doi: 10.1038/s41467-021-26596-y. Nat Commun. 2021. PMID: 34764250 Free PMC article.
Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement.
Bratslavsky G, Mendhiratta N, Daneshvar M, Brugarolas J, Ball MW, Metwalli A, Nathanson KL, Pierorazio PM, Boris RS, Singer EA, Carlo MI, Daly MB, Henske EP, Hyatt C, Middleton L, Morris G, Jeong A, Narayan V, Rathmell WK, Vaishampayan U, Lee BH, Battle D, Hall MJ, Hafez K, Jewett MAS, Karamboulas C, Pal SK, Hakimi AA, Kutikov A, Iliopoulos O, Linehan WM, Jonasch E, Srinivasan R, Shuch B. Bratslavsky G, et al. Among authors: henske ep. Cancer. 2021 Nov 1;127(21):3957-3966. doi: 10.1002/cncr.33679. Epub 2021 Aug 3. Cancer. 2021. PMID: 34343338 Free PMC article.
The TSC Complex-mTORC1 Axis: From Lysosomes to Stress Granules and Back.
Rehbein U, Prentzell MT, Cadena Sandoval M, Heberle AM, Henske EP, Opitz CA, Thedieck K. Rehbein U, et al. Among authors: henske ep. Front Cell Dev Biol. 2021 Oct 29;9:751892. doi: 10.3389/fcell.2021.751892. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34778262 Free PMC article. Review.
Renal Cell Carcinoma in Tuberous Sclerosis Complex.
Henske EP, Cornejo KM, Wu CL. Henske EP, et al. Genes (Basel). 2021 Oct 8;12(10):1585. doi: 10.3390/genes12101585. Genes (Basel). 2021. PMID: 34680979 Free PMC article. Review.
Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Wang J, Filippakis H, Hougard T, Du H, Ye C, Liu HJ, Zhang L, Hindi K, Bagwe S, Nijmeh J, Asara JM, Shi W, El-Chemaly S, Henske EP, Lam HC. Wang J, et al. Among authors: henske ep. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2101268118. doi: 10.1073/pnas.2101268118. Proc Natl Acad Sci U S A. 2021. PMID: 34544857 Free PMC article.
TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.
Kosmas K, Filippakis H, Khabibullin D, Turkiewicz M, Lam HC, Yu J, Kedersha NL, Anderson PJ, Henske EP. Kosmas K, et al. Among authors: henske ep. Mol Cancer Res. 2021 Aug;19(8):1389-1397. doi: 10.1158/1541-7786.MCR-20-1046. Epub 2021 Apr 22. Mol Cancer Res. 2021. PMID: 33888601 Free article.
mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury.
Lee H, Fei Q, Streicher A, Zhang W, Isabelle C, Patel P, Lam HC, Arciniegas-Rubio A, Pinilla-Vera M, Amador-Munoz DP, Barragan-Bradford D, Higuera-Moreno A, Putman RK, Sholl LM, Henske EP, Bobba CM, Higuita-Castro N, Shalosky EM, Hite RD, Christman JW, Ghadiali SN, Baron RM, Englert JA. Lee H, et al. Among authors: henske ep. JCI Insight. 2021 Jul 22;6(14):e137708. doi: 10.1172/jci.insight.137708. JCI Insight. 2021. PMID: 34138757 Free PMC article.
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J. Csibi A, et al. Among authors: henske ep. Cell. 2021 Apr 15;184(8):2256. doi: 10.1016/j.cell.2021.03.059. Cell. 2021. PMID: 33861966 Free article. No abstract available.
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Kovalenko A, Sanin A, Kosmas K, Zhang L, Wang J, Akl EW, Giannikou K, Probst CK, Hougard TR, Rue RW, Krymskaya VP, Asara JM, Lam HC, Kwiatkowski DJ, Henske EP, Filippakis H. Kovalenko A, et al. Among authors: henske ep. Cancer Res. 2021 Apr 15;81(8):2086-2100. doi: 10.1158/0008-5472.CAN-20-2218. Epub 2021 Feb 16. Cancer Res. 2021. PMID: 33593821 Free PMC article.
Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Lam HC, Baglini CV, Lope AL, Parkhitko AA, Liu HJ, Alesi N, Malinowska IA, Ebrahimi-Fakhari D, Saffari A, Yu JJ, Pereira A, Khabibullin D, Ogorek B, Nijmeh J, Kavanagh T, Handen A, Chan SY, Asara JM, Oldham WM, Diaz-Meco MT, Moscat J, Sahin M, Priolo C, Henske EP. Lam HC, et al. Among authors: henske ep. Cancer Res. 2020 Dec 1;80(23):5424. doi: 10.1158/0008-5472.CAN-20-3417. Cancer Res. 2020. PMID: 33268556 No abstract available.
Tumour predisposition and cancer syndromes as models to study gene-environment interactions.
Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, Mak TW, Malkin D, Monnat RJ Jr, Novelli F, Pass HI, Petrini JH, Schmidt LS, Yang H. Carbone M, et al. Among authors: henske ep. Nat Rev Cancer. 2020 Sep;20(9):533-549. doi: 10.1038/s41568-020-0265-y. Epub 2020 May 29. Nat Rev Cancer. 2020. PMID: 32472073 Free PMC article. Review.
Celecoxib in lymphangioleiomyomatosis: results of a phase I clinical trial.
El-Chemaly S, Taveira-DaSilva A, Bagwe S, Klonowska K, Machado T, Lamattina AM, Goldberg HJ, Jones AM, Julien-Williams P, Maurer R, Rosas IO, Henske EP, Moss J, Kwiatkowski DJ. El-Chemaly S, et al. Among authors: henske ep. Eur Respir J. 2020 May 27;55(5):1902370. doi: 10.1183/13993003.02370-2019. Print 2020 May. Eur Respir J. 2020. PMID: 32060062 Free article. Clinical Trial. No abstract available.
IMPDH inhibitors for antitumor therapy in tuberous sclerosis complex.
Valvezan AJ, McNamara MC, Miller SK, Torrence ME, Asara JM, Henske EP, Manning BD. Valvezan AJ, et al. Among authors: henske ep. JCI Insight. 2020 Apr 9;5(7):e135071. doi: 10.1172/jci.insight.135071. JCI Insight. 2020. PMID: 32271165 Free PMC article.
Generalised mosaicism for TSC2 mutation in isolated lymphangioleiomyomatosis.
Ogórek B, Hamieh L, Lasseter K, Bagwe S, Machado T, Herranz-Ors C, Thorner AR, Nag A, Gulleman P, Giannikou K, Young LR, Pujana MÀ, Darling TN, El-Chemaly S, Moss J, Henske EP, Kwiatkowski DJ. Ogórek B, et al. Among authors: henske ep. Eur Respir J. 2019 Oct 10;54(4):1900938. doi: 10.1183/13993003.00938-2019. Print 2019 Oct. Eur Respir J. 2019. PMID: 31273045 Free PMC article. No abstract available.
Loss of FLCN inhibits canonical WNT signaling via TFE3.
Kennedy JC, Khabibullin D, Hougard T, Nijmeh J, Shi W, Henske EP. Kennedy JC, et al. Among authors: henske ep. Hum Mol Genet. 2019 Oct 1;28(19):3270-3281. doi: 10.1093/hmg/ddz158. Hum Mol Genet. 2019. PMID: 31272105 Free PMC article.
The Codon 72 TP53 Polymorphism Contributes to TSC Tumorigenesis through the Notch-Nodal Axis.
Cho JH, Patel B, Bonala S, Mansouri H, Manne S, Vadrevu SK, Ghouse S, Kung CP, Murphy ME, Astrinidis A, Henske EP, Kwiatkowski DJ, Markiewski MM, Karbowniczek M. Cho JH, et al. Among authors: henske ep. Mol Cancer Res. 2019 Aug;17(8):1639-1651. doi: 10.1158/1541-7786.MCR-18-1292. Epub 2019 May 14. Mol Cancer Res. 2019. PMID: 31088907 Free PMC article.
A genome-wide association study implicates NR2F2 in lymphangioleiomyomatosis pathogenesis.
Kim W, Giannikou K, Dreier JR, Lee S, Tyburczy ME, Silverman EK, Radzikowska E, Wu S, Wu CL, Henske EP, Hunninghake G, Carel H, Roman A, Pujana MA, Moss J, Won S, Kwiatkowski DJ. Kim W, et al. Among authors: henske ep. Eur Respir J. 2019 Jun 27;53(6):1900329. doi: 10.1183/13993003.00329-2019. Print 2019 Jun. Eur Respir J. 2019. PMID: 31000673 Free article.
The Genetics of Pneumothorax.
Boone PM, Scott RM, Marciniak SJ, Henske EP, Raby BA. Boone PM, et al. Among authors: henske ep. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1344-1357. doi: 10.1164/rccm.201807-1212CI. Am J Respir Crit Care Med. 2019. PMID: 30681372 Free PMC article. Review.
Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis.
Lamattina AM, Poli S, Kidambi P, Bagwe S, Courtwright A, Louis PH, Shrestha S, Stump B, Goldberg HJ, Thiele EA, Rosas I, Henske EP, El-Chemaly S. Lamattina AM, et al. Among authors: henske ep. Orphanet J Rare Dis. 2019 Mar 29;14(1):72. doi: 10.1186/s13023-019-1050-4. Orphanet J Rare Dis. 2019. PMID: 30922357 Free PMC article.
Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease.
Han MK, Arteaga-Solis E, Blenis J, Bourjeily G, Clegg DJ, DeMeo D, Duffy J, Gaston B, Heller NM, Hemnes A, Henske EP, Jain R, Lahm T, Lancaster LH, Lee J, Legato MJ, McKee S, Mehra R, Morris A, Prakash YS, Stampfli MR, Gopal-Srivastava R, Laposky AD, Punturieri A, Reineck L, Tigno X, Clayton J. Han MK, et al. Among authors: henske ep. Am J Respir Crit Care Med. 2018 Oct 1;198(7):850-858. doi: 10.1164/rccm.201801-0168WS. Am J Respir Crit Care Med. 2018. PMID: 29746147 Free PMC article. Review.
Pulmonary manifestations in tuberous sclerosis complex.
Gupta N, Henske EP. Gupta N, et al. Among authors: henske ep. Am J Med Genet C Semin Med Genet. 2018 Sep;178(3):326-337. doi: 10.1002/ajmg.c.31638. Epub 2018 Jul 28. Am J Med Genet C Semin Med Genet. 2018. PMID: 30055039 Free PMC article. Review.
Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma.
Priolo C, Khabibullin D, Reznik E, Filippakis H, Ogórek B, Kavanagh TR, Nijmeh J, Herbert ZT, Asara JM, Kwiatkowski DJ, Wu CL, Henske EP. Priolo C, et al. Among authors: henske ep. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6274-E6282. doi: 10.1073/pnas.1710849115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891694 Free PMC article.
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG; Cancer Genome Atlas Research Network; Spellman PT, Rathmell WK, Linehan WM. Ricketts CJ, et al. Among authors: henske ep. Cell Rep. 2018 Jun 19;23(12):3698. doi: 10.1016/j.celrep.2018.06.032. Cell Rep. 2018. PMID: 29925010 Free article. No abstract available.
TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.
Ogórek B, Lam HC, Khabibullin D, Liu HJ, Nijmeh J, Triboulet R, Kwiatkowski DJ, Gregory RI, Henske EP. Ogórek B, et al. Among authors: henske ep. Hum Mol Genet. 2018 May 1;27(9):1654-1663. doi: 10.1093/hmg/ddy073. Hum Mol Genet. 2018. PMID: 29509898 Free PMC article.
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Liu W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG; Cancer Genome Atlas Research Network; Spellman PT, Rathmell WK, Linehan WM. Ricketts CJ, et al. Among authors: henske ep. Cell Rep. 2018 Apr 3;23(1):313-326.e5. doi: 10.1016/j.celrep.2018.03.075. Cell Rep. 2018. PMID: 29617669 Free PMC article.
Familial pneumothorax: towards precision medicine.
Scott RM, Henske EP, Raby B, Boone PM, Rusk RA, Marciniak SJ. Scott RM, et al. Among authors: henske ep. Thorax. 2018 Mar;73(3):270-276. doi: 10.1136/thoraxjnl-2017-211169. Epub 2017 Dec 28. Thorax. 2018. PMID: 29288214 Review.
Emerging biomarkers of lymphangioleiomyomatosis.
Nijmeh J, El-Chemaly S, Henske EP. Nijmeh J, et al. Among authors: henske ep. Expert Rev Respir Med. 2018 Feb;12(2):95-102. doi: 10.1080/17476348.2018.1409622. Epub 2017 Dec 1. Expert Rev Respir Med. 2018. PMID: 29171770 Review.
Characterization of lymphangioleiomyomatosis patients with discordance between spirometric and diffusion measurements of pulmonary function.
Courtwright AM, Baldi BG, Kidambi P, Cui Y, Lamattina AM, Villalba JA, Bagwe S, Goldberg HJ, Rosas IO, Henske EP, Carvalho CRR, El-Chemaly S. Courtwright AM, et al. Among authors: henske ep. Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(3):206-212. doi: 10.36141/svdld.v35i3.6321. Epub 2018 Apr 28. Sarcoidosis Vasc Diffuse Lung Dis. 2018. PMID: 32476904 Free PMC article.
Notch transactivates Rheb to maintain the multipotency of TSC-null cells.
Cho JH, Patel B, Bonala S, Manne S, Zhou Y, Vadrevu SK, Patel J, Peronaci M, Ghouse S, Henske EP, Roegiers F, Giannikou K, Kwiatkowski DJ, Mansouri H, Markiewski MM, White B, Karbowniczek M. Cho JH, et al. Among authors: henske ep. Nat Commun. 2017 Nov 29;8(1):1848. doi: 10.1038/s41467-017-01845-1. Nat Commun. 2017. PMID: 29184052 Free PMC article.
Human Pluripotent Stem Cell-Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis.
Julian LM, Delaney SP, Wang Y, Goldberg AA, Doré C, Yockell-Lelièvre J, Tam RY, Giannikou K, McMurray F, Shoichet MS, Harper ME, Henske EP, Kwiatkowski DJ, Darling TN, Moss J, Kristof AS, Stanford WL. Julian LM, et al. Among authors: henske ep. Cancer Res. 2017 Oct 15;77(20):5491-5502. doi: 10.1158/0008-5472.CAN-17-0925. Epub 2017 Aug 22. Cancer Res. 2017. PMID: 28830860 Free PMC article.
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.
Lam HC, Liu HJ, Baglini CV, Filippakis H, Alesi N, Nijmeh J, Du H, Lope AL, Cottrill KA, Handen A, Asara JM, Kwiatkowski DJ, Ben-Sahra I, Oldham WM, Chan SY, Henske EP. Lam HC, et al. Among authors: henske ep. Oncotarget. 2017 Aug 4;8(39):64714-64727. doi: 10.18632/oncotarget.19947. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029388 Free PMC article.
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Lam HC, Baglini CV, Lope AL, Parkhitko AA, Liu HJ, Alesi N, Malinowska IA, Ebrahimi-Fakhari D, Saffari A, Yu JJ, Pereira A, Khabibullin D, Ogorek B, Nijmeh J, Kavanagh T, Handen A, Chan SY, Asara JM, Oldham WM, Diaz-Meco MT, Moscat J, Sahin M, Priolo C, Henske EP. Lam HC, et al. Among authors: henske ep. Cancer Res. 2017 Jun 15;77(12):3255-3267. doi: 10.1158/0008-5472.CAN-16-2458. Epub 2017 May 16. Cancer Res. 2017. PMID: 28512249 Free PMC article.
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.
Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, Zhang J, Yang L, Seth S, Lee S, Ren X, Song X, Sun H, Seidman J, Luquette LJ, Xi R, Chin L, Protopopov A, Westbrook TF, Shelley CS, Choueiri TK, Ittmann M, Van Waes C, Weinstein JN, Liang H, Henske EP, Godwin AK, Park PJ, Kucherlapati R, Scott KL, Mills GB, Kwiatkowski DJ, Creighton CJ. Zhang Y, et al. Among authors: henske ep. Cancer Cell. 2017 Jun 12;31(6):820-832.e3. doi: 10.1016/j.ccell.2017.04.013. Epub 2017 May 18. Cancer Cell. 2017. PMID: 28528867 Free PMC article.
Sirolimus and Autophagy Inhibition in Lymphangioleiomyomatosis: Results of a Phase I Clinical Trial.
El-Chemaly S, Taveira-Dasilva A, Goldberg HJ, Peters E, Haughey M, Bienfang D, Jones AM, Julien-Williams P, Cui Y, Villalba JA, Bagwe S, Maurer R, Rosas IO, Moss J, Henske EP. El-Chemaly S, et al. Among authors: henske ep. Chest. 2017 Jun;151(6):1302-1310. doi: 10.1016/j.chest.2017.01.033. Epub 2017 Feb 10. Chest. 2017. PMID: 28192114 Free PMC article. Clinical Trial.
Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome.
Gupta N, Kopras EJ, Henske EP, James LE, El-Chemaly S, Veeraraghavan S, Drake MG, McCormack FX. Gupta N, et al. Among authors: henske ep. Ann Am Thorac Soc. 2017 May;14(5):706-713. doi: 10.1513/AnnalsATS.201611-886OC. Ann Am Thorac Soc. 2017. PMID: 28248571 Free PMC article.
Aberrant SYK Kinase Signaling Is Essential for Tumorigenesis Induced by TSC2 Inactivation.
Cui Y, Steagall WK, Lamattina AM, Pacheco-Rodriguez G, Stylianou M, Kidambi P, Stump B, Golzarri F, Rosas IO, Priolo C, Henske EP, Moss J, El-Chemaly S. Cui Y, et al. Among authors: henske ep. Cancer Res. 2017 Mar 15;77(6):1492-1502. doi: 10.1158/0008-5472.CAN-16-2755. Epub 2017 Feb 15. Cancer Res. 2017. PMID: 28202529 Free PMC article.
Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation.
Peri S, Caretti E, Tricarico R, Devarajan K, Cheung M, Sementino E, Menges CW, Nicolas E, Vanderveer LA, Howard S, Conrad P, Crowell JA, Campbell KS, Ross EA, Godwin AK, Yeung AT, Clapper ML, Uzzo RG, Henske EP, Ricketts CJ, Vocke CD, Linehan WM, Testa JR, Bellacosa A, Kopelovich L, Knudson AG. Peri S, et al. Among authors: henske ep. Oncotarget. 2017 Mar 14;8(11):17628-17642. doi: 10.18632/oncotarget.12192. Oncotarget. 2017. PMID: 27682873 Free PMC article.
Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management.
McCormack FX, Gupta N, Finlay GR, Young LR, Taveira-DaSilva AM, Glasgow CG, Steagall WK, Johnson SR, Sahn SA, Ryu JH, Strange C, Seyama K, Sullivan EJ, Kotloff RM, Downey GP, Chapman JT, Han MK, D'Armiento JM, Inoue Y, Henske EP, Bissler JJ, Colby TV, Kinder BW, Wikenheiser-Brokamp KA, Brown KK, Cordier JF, Meyer C, Cottin V, Brozek JL, Smith K, Wilson KC, Moss J; ATS/JRS Committee on Lymphangioleiomyomatosis. McCormack FX, et al. Among authors: henske ep. Am J Respir Crit Care Med. 2016 Sep 15;194(6):748-61. doi: 10.1164/rccm.201607-1384ST. Am J Respir Crit Care Med. 2016. PMID: 27628078 Free PMC article.
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.
Giannikou K, Malinowska IA, Pugh TJ, Yan R, Tseng YY, Oh C, Kim J, Tyburczy ME, Chekaluk Y, Liu Y, Alesi N, Finlay GA, Wu CL, Signoretti S, Meyerson M, Getz G, Boehm JS, Henske EP, Kwiatkowski DJ. Giannikou K, et al. Among authors: henske ep. PLoS Genet. 2016 Aug 5;12(8):e1006242. doi: 10.1371/journal.pgen.1006242. eCollection 2016 Aug. PLoS Genet. 2016. PMID: 27494029 Free PMC article.
Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference.
Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA; Tuberous Sclerosis Complex Working Group to Update the Research Plan. Sahin M, et al. Among authors: henske ep. Pediatr Neurol. 2016 Jul;60:1-12. doi: 10.1016/j.pediatrneurol.2016.03.015. Epub 2016 Apr 2. Pediatr Neurol. 2016. PMID: 27267556 Free PMC article.
Tuberous sclerosis complex.
Henske EP, Jóźwiak S, Kingswood JC, Sampson JR, Thiele EA. Henske EP, et al. Nat Rev Dis Primers. 2016 May 26;2:16035. doi: 10.1038/nrdp.2016.35. Nat Rev Dis Primers. 2016. PMID: 27226234 Review.
Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.
Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, Muzny D, Kang H, Lee J, Tamboli P, Reuter V, Shelley CS, Kaipparettu BA, Bottaro DP, Godwin AK, Gibbs RA, Getz G, Kucherlapati R, Park PJ, Sander C, Henske EP, Zhou JH, Kwiatkowski DJ, Ho TH, Choueiri TK, Hsieh JJ, Akbani R, Mills GB, Hakimi AA, Wheeler DA, Creighton CJ. Chen F, et al. Among authors: henske ep. Cell Rep. 2016 Mar 15;14(10):2476-89. doi: 10.1016/j.celrep.2016.02.024. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947078 Free PMC article.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, … See abstract for full author list ➔ Klionsky DJ, et al. Among authors: henske ep. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Autophagy. 2016. PMID: 26799652 Free PMC article. No abstract available.
Unjamming and cell shape in the asthmatic airway epithelium.
Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R Jr, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Park JA, et al. Among authors: henske ep. Nat Mater. 2015 Oct;14(10):1040-8. doi: 10.1038/nmat4357. Epub 2015 Aug 3. Nat Mater. 2015. PMID: 26237129 Free PMC article.
Everolimus for the treatment of lymphangioleiomyomatosis: a phase II study.
Goldberg HJ, Harari S, Cottin V, Rosas IO, Peters E, Biswal S, Cheng Y, Khindri S, Kovarik JM, Ma S, McCormack FX, Henske EP. Goldberg HJ, et al. Among authors: henske ep. Eur Respir J. 2015 Sep;46(3):783-94. doi: 10.1183/09031936.00210714. Epub 2015 Jun 25. Eur Respir J. 2015. PMID: 26113676 Free article. Clinical Trial.
Targeted deletion of Tsc1 causes fatal cardiomyocyte hyperplasia independently of afterload.
Kayyali US, Larsen CG, Bashiruddin S, Lewandowski SL, Trivedi CM, Warburton RR, Parkhitko AA, Morrison TA, Henske EP, Chekaluk Y, Kwiatkowski DJ, Finlay GA. Kayyali US, et al. Among authors: henske ep. Cardiovasc Pathol. 2015 Mar-Apr;24(2):80-93. doi: 10.1016/j.carpath.2014.10.005. Epub 2014 Nov 7. Cardiovasc Pathol. 2015. PMID: 25434723 Free PMC article.
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, Gallazzini M, Olson EN, Lam H, Henske EP, Dong Z, Apte U, Pallet N, Johnson RL, Terzi F, Kwiatkowski DJ, Scoazec JY, Martignoni G, Pende M. Liang N, et al. Among authors: henske ep. J Exp Med. 2014 Oct 20;211(11):2249-63. doi: 10.1084/jem.20140341. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288394 Free PMC article.
The somatic genomic landscape of chromophobe renal cell carcinoma.
Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, Biehl M, Seth S, Kaipparettu BA, Bristow CA, Donehower LA, Wallen EM, Smith AB, Tickoo SK, Tamboli P, Reuter V, Schmidt LS, Hsieh JJ, Choueiri TK, Hakimi AA; The Cancer Genome Atlas Research Network; Chin L, Meyerson M, Kucherlapati R, Park WY, Robertson AG, Laird PW, Henske EP, Kwiatkowski DJ, Park PJ, Morgan M, Shuch B, Muzny D, Wheeler DA, Linehan WM, Gibbs RA, Rathmell WK, Creighton CJ. Davis CF, et al. Among authors: henske ep. Cancer Cell. 2014 Sep 8;26(3):319-330. doi: 10.1016/j.ccr.2014.07.014. Epub 2014 Aug 21. Cancer Cell. 2014. PMID: 25155756 Free PMC article.
Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment.
Sadow PM, Priolo C, Nanni S, Karreth FA, Duquette M, Martinelli R, Husain A, Clohessy J, Kutzner H, Mentzel T, Carman CV, Farsetti A, Henske EP, Palescandolo E, Macconaill LE, Chung S, Fadda G, Lombardi CP, De Angelis AM, Durante O, Parker JA, Pontecorvi A, Dvorak HF, Fletcher C, Pandolfi PP, Lawler J, Nucera C. Sadow PM, et al. Among authors: henske ep. J Natl Cancer Inst. 2014 Jul 25;106(8):dju182. doi: 10.1093/jnci/dju182. Print 2014 Aug. J Natl Cancer Inst. 2014. PMID: 25063326 Free PMC article.
Renal cell carcinoma in tuberous sclerosis complex.
Yang P, Cornejo KM, Sadow PM, Cheng L, Wang M, Xiao Y, Jiang Z, Oliva E, Jozwiak S, Nussbaum RL, Feldman AS, Paul E, Thiele EA, Yu JJ, Henske EP, Kwiatkowski DJ, Young RH, Wu CL. Yang P, et al. Among authors: henske ep. Am J Surg Pathol. 2014 Jul;38(7):895-909. doi: 10.1097/PAS.0000000000000237. Am J Surg Pathol. 2014. PMID: 24832166 Free PMC article.
Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells.
Li C, Lee PS, Sun Y, Gu X, Zhang E, Guo Y, Wu CL, Auricchio N, Priolo C, Li J, Csibi A, Parkhitko A, Morrison T, Planaguma A, Kazani S, Israel E, Xu KF, Henske EP, Blenis J, Levy BD, Kwiatkowski D, Yu JJ. Li C, et al. Among authors: henske ep. J Exp Med. 2014 Jan 13;211(1):15-28. doi: 10.1084/jem.20131080. Epub 2014 Jan 6. J Exp Med. 2014. PMID: 24395886 Free PMC article.
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, Locasale JW, Asara JM, Choi AM, Finkel T, Henske EP. Parkhitko AA, et al. Among authors: henske ep. Mol Cancer Res. 2014 Jan;12(1):48-57. doi: 10.1158/1541-7786.MCR-13-0258-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296756 Free PMC article.
Reply: Characterization of lymphangioleiomyomatosis as a neoplastic disease.
McCormack FX, Travis WD, Colby TV, Henske EP, Moss J. McCormack FX, et al. Among authors: henske ep. Am J Respir Crit Care Med. 2013 Aug 1;188(3):398-9. doi: 10.1164/rccm.201301-0199LE. Am J Respir Crit Care Med. 2013. PMID: 23905529 Free PMC article. No abstract available.
Lymphangioleiomyomatosis - a wolf in sheep's clothing.
Henske EP, McCormack FX. Henske EP, et al. J Clin Invest. 2012 Nov;122(11):3807-16. doi: 10.1172/JCI58709. Epub 2012 Nov 1. J Clin Invest. 2012. PMID: 23114603 Free PMC article. Review.
Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC Jr, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pier… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: henske ep. Autophagy. 2012 Apr;8(4):445-544. doi: 10.4161/auto.19496. Autophagy. 2012. PMID: 22966490 Free PMC article.
Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Medvetz DA, Khabibullin D, Hariharan V, Ongusaha PP, Goncharova EA, Schlechter T, Darling TN, Hofmann I, Krymskaya VP, Liao JK, Huang H, Henske EP. Medvetz DA, et al. Among authors: henske ep. PLoS One. 2012;7(11):e47842. doi: 10.1371/journal.pone.0047842. Epub 2012 Nov 6. PLoS One. 2012. PMID: 23139756 Free PMC article.
The International LAM Registry: a component of an innovative web-based clinician, researcher, and patient-driven rare disease research platform.
Nurok M, Eslick I, Carvalho CR, Costabel U, D'Armiento J, Glanville AR, Harari S, Henske EP, Inoue Y, Johnson SR, Lacronique J, Lazor R, Moss J, Ruoss SJ, Ryu JH, Seyama K, Watz H, Xu KF, Hohmann EL, Moss F. Nurok M, et al. Among authors: henske ep. Lymphat Res Biol. 2010 Mar;8(1):81-7. doi: 10.1089/lrb.2009.0028. Lymphat Res Biol. 2010. PMID: 20235890 Free article.
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Yu JJ, Robb VA, Morrison TA, Ariazi EA, Karbowniczek M, Astrinidis A, Wang C, Hernandez-Cuebas L, Seeholzer LF, Nicolas E, Hensley H, Jordan VC, Walker CL, Henske EP. Yu JJ, et al. Among authors: henske ep. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2635-40. doi: 10.1073/pnas.0810790106. Epub 2009 Feb 6. Proc Natl Acad Sci U S A. 2009. PMID: 19202070 Free PMC article.
mTOR is activated in the majority of malignant melanomas.
Karbowniczek M, Spittle CS, Morrison T, Wu H, Henske EP. Karbowniczek M, et al. Among authors: henske ep. J Invest Dermatol. 2008 Apr;128(4):980-7. doi: 10.1038/sj.jid.5701074. Epub 2007 Oct 4. J Invest Dermatol. 2008. PMID: 17914450 Free article.
Analysis of published PKD1 gene sequence variants.
Gout AM; ADPKD Gene Variant Consortium; Ravine D, Harris PC, Rossetti S, Peters D, Breuning M, Henske EP, Koizumi A, Inoue S, Shimizu Y, Thongnoppakhun W, Yenchitsomanus PT, Deltas C, Sandford R, Torra R, Turco AE, Jeffery S, Fontes M, Somlo S, Furu LM, Smulders YM, Mercier B, Ferec C, Burtey S, Pei Y, Kalaydjieva L, Bogdanova N, McCluskey M, Geon LJ, Wouters CH, Reiterova J, Stekrová J, San Millan JL, Aguiari G, Del Senno L. Gout AM, et al. Among authors: henske ep. Nat Genet. 2007 Apr;39(4):427-8. doi: 10.1038/ng0407-427. Nat Genet. 2007. PMID: 17392796 Review. No abstract available.
The tuberous sclerosis complex.
Crino PB, Nathanson KL, Henske EP. Crino PB, et al. Among authors: henske ep. N Engl J Med. 2006 Sep 28;355(13):1345-56. doi: 10.1056/NEJMra055323. N Engl J Med. 2006. PMID: 17005952 Review. No abstract available.
Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization.
Karbowniczek M, Robertson GP, Henske EP. Karbowniczek M, et al. Among authors: henske ep. J Biol Chem. 2006 Sep 1;281(35):25447-56. doi: 10.1074/jbc.M605273200. Epub 2006 Jun 27. J Biol Chem. 2006. PMID: 16803888 Free article.
Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations.
Stoyanova R, Clapper ML, Bellacosa A, Henske EP, Testa JR, Ross EA, Yeung AT, Nicolas E, Tsichlis N, Li YS, Linehan WM, Howard S, Campbell KS, Godwin AK, Boman BM, Crowell JA, Kopelovich L, Knudson AG. Stoyanova R, et al. Among authors: henske ep. Cancer Biol Ther. 2004 Dec;3(12):1313-21. doi: 10.4161/cbt.3.12.1459. Epub 2004 Dec 9. Cancer Biol Ther. 2004. PMID: 15662135 Free article.
Pulmonary lymphangioleiomyomatosis in a man.
Aubry MC, Myers JL, Ryu JH, Henske EP, Logginidou H, Jalal SM, Tazelaar HD. Aubry MC, et al. Among authors: henske ep. Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):749-52. doi: 10.1164/ajrccm.162.2.9911006. Am J Respir Crit Care Med. 2000. PMID: 10934115
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.
van Slegtenhorst M, de Hoogt R, Hermans C, Nellist M, Janssen B, Verhoef S, Lindhout D, van den Ouweland A, Halley D, Young J, Burley M, Jeremiah S, Woodward K, Nahmias J, Fox M, Ekong R, Osborne J, Wolfe J, Povey S, Snell RG, Cheadle JP, Jones AC, Tachataki M, Ravine D, Sampson JR, Reeve MP, Richardson P, Wilmer F, Munro C, Hawkins TL, Sepp T, Ali JB, Ward S, Green AJ, Yates JR, Kwiatkowska J, Henske EP, Short MP, Haines JH, Jozwiak S, Kwiatkowski DJ. van Slegtenhorst M, et al. Among authors: henske ep. Science. 1997 Aug 8;277(5327):805-8. doi: 10.1126/science.277.5327.805. Science. 1997. PMID: 9242607
Aggressive variants of chromophobe renal cell carcinoma.
Renshaw AA, Henske EP, Loughlin KR, Shapiro C, Weinberg DS. Renshaw AA, et al. Among authors: henske ep. Cancer. 1996 Oct 15;78(8):1756-61. doi: 10.1002/(sici)1097-0142(19961015)78:8<1756::aid-cncr16>3.0.co;2-x. Cancer. 1996. PMID: 8859189 Review.
208 results