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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 1
1997 1
1998 7
1999 7
2000 14
2001 21
2002 19
2003 19
2004 32
2005 21
2006 28
2007 31
2008 23
2009 41
2010 25
2011 34
2012 42
2013 35
2014 40
2015 37
2016 21
2017 30
2018 30
2019 12
2020 0
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509 results
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Page 1
Heparan sulfate proteoglycans.
Sarrazin S, et al. Cold Spring Harb Perspect Biol 2011 - Review. PMID 21690215 Free PMC article.
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a plethora of ligands. ...Although few in number, heparan sulfate proteoglycans have profound effects at the cellular, tissue, and organismal level....
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a
Heparan sulfate proteoglycans: a sugar code for vertebrate development?
Poulain FE and Yost HJ. Development 2015 - Review. PMID 26487777 Free PMC article.
Heparan sulfate proteoglycans (HSPGs) have long been implicated in a wide range of cell-cell signaling and cell-matrix interactions, both in vitro and in vivo in invertebrate models. ...Here, we provide a comprehensive overview of the various roles of HSPGs in these systems and explore the concept of an instructive heparan sulfate sugar code for modulating vertebrate development....
Heparan sulfate proteoglycans (HSPGs) have long been implicated in a wide range of cell-cell signaling and cell-matrix
The heparan sulfate proteoglycan grip on hyperlipidemia and atherosclerosis.
Gordts PLSM and Esko JD. Matrix Biol 2018 - Review. PMID 29803939 Free PMC article.
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a plethora of proteins involved in lipid homeostasis and inflammation. ...Here, we discuss novel insights into how heparan sulfate proteoglycans modulate risk factors such as hyperlipidemia and inflammation that drive the initiation and progression of atherosclerotic plaques to their clinical critical endpoint....
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a
Targeting Heparan Sulfate Proteoglycans and their Modifying Enzymes to Enhance Anticancer Chemotherapy Efficacy and Overcome Drug Resistance.
Lanzi C, et al. Curr Med Chem 2017 - Review. PMID 28215163
Targeting heparan sulfate proteoglycans (HSPGs) and enzymes involved in heparan sulfate (HS) chain editing is emerging as a new anticancer strategy. ...
Targeting heparan sulfate proteoglycans (HSPGs) and enzymes involved in heparan sulfate (HS) chain editin …
Proteoglycans in liver cancer.
Baghy K, et al. World J Gastroenterol 2016 - Review. PMID 26755884 Free PMC article.
Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain, such as a heparan, dermatan, chondroitin, or keratan sulfate, covalently attached to the protein core. ...Cell-surface heparan sulfate proteoglycans, such as syndecans, are the primary type present in healthy liver tissue. However, deterioration of the liver results in overproduction of other proteoglycan types. ...
Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain, such as a heparan, dermatan, chondro
Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers.
Hull EE, et al. Int J Mol Sci 2017 - Review. PMID 28672878 Free PMC article.
Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of heparan sulfate proteoglycans (HSPGs) are epigenetically regulated at many levels. As the exact composition of the heparan sulfate portion of the resulting HSPG molecules is critical to the broad spectrum of biological processes involved in oncogenesis, the epigenetic regulation of heparan sulfate biosynthesis has far-reaching effects on many cellular activities related to cancer progression. ...
Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of he
Heparan sulfate proteoglycans: structure, protein interactions and cell signaling.
Dreyfuss JL, et al. An Acad Bras Cienc 2009 - Review. PMID 19722012 Free article.
Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal species. ...The role of the heparan sulfate proteoglycans in cellular signaling and endocytic uptake pathways is also discussed....
Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal spe
Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions.
Tumova S, et al. Int J Biochem Cell Biol 2000 - Review. PMID 10716625
Heparan sulfate proteoglycans are complex molecules composed of a core protein with covalently attached glycosaminoglycan chains. ...Through these interactions, heparan sulfate proteoglycans participate in many events during cell adhesion, migration, proliferation and differentiation. ...
Heparan sulfate proteoglycans are complex molecules composed of a core protein with covalently attached glycosaminoglyc
Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment
Zhou F, et al. Med Res Rev 2018 - Review. PMID 28621802
Glypican-3 (GPC3), an oncofetal proteoglycan anchored to the cell membrane, is normally detected in the fetal liver but not in the healthy adult liver. ...
Glypican-3 (GPC3), an oncofetal proteoglycan anchored to the cell membrane, is normally detected in the fetal liver but not in the he …
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