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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 12
1981 25
1982 23
1983 26
1984 34
1985 36
1986 34
1987 36
1988 33
1989 27
1990 31
1991 49
1992 20
1993 22
1994 25
1995 32
1996 20
1997 24
1998 17
1999 20
2000 24
2001 19
2002 16
2003 25
2004 32
2005 31
2006 45
2007 43
2008 27
2009 25
2010 35
2011 55
2012 40
2013 49
2014 53
2015 47
2016 35
2017 35
2018 32
2019 13
2020 0
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1,171 results
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Page 1
Hepatitis B Virus e Antigen Regulates Monocyte Function and Promotes B Lymphocyte Activation.
Lu B, et al. Viral Immunol 2017. PMID 27976981 Free PMC article.
Hepatitis B virus (HBV) e (HBe) antigen is a nonstructural virus component with great immune regulation roles. It regulates adaptive immunity response and participates in persistent infection development. ...Activation and inhibition markers of B lymphocytes on HBe-Hmy2.CIR and proliferation of transfected Hmy2.CIR after coculture with transfected U937 were also detected. ...
Hepatitis B virus (HBV) e (HBe) antigen is a nonstructural virus component with great immune regulation roles. It regul
Systematic review and meta-analysis: Development of hepatocellular carcinoma in chronic hepatitis B patients with hepatitis e antigen seroconversion.
Zhou TC, et al. J Viral Hepat 2018. PMID 29741285
Hepatitis B e antigen (HBeAg) seroconversion is considered to have significantly favourable clinical outcomes for patients with chronic hepatitis B (CHB). ...Long-term monitoring is needed for patients with established cirrhosis, active hepatitis or those older than 40 years at the time of HBeAg seroconversion....
Hepatitis B e antigen (HBeAg) seroconversion is considered to have significantly favourable clinical outcomes for patie
Kinetic Changes of Viremia and Viral Antigens of Hepatitis B Virus During and After Pregnancy.
Liu J, et al. Medicine (Baltimore) 2015 - Clinical Trial. PMID 26559291 Free PMC article.
Whether pregnancy may influence the replication of hepatitis B virus (HBV) remains unknown. The authors aimed to clarify this issue by observing the kinetics of HBV deoxyribonucleic acid (DNA) and viral antigens in women during and after pregnancy. Total, 371 pregnant women with positive hepatitis B surface antigen (HBsAg) were enrolled. Serial sera collected during and after pregnancy were quantitatively measured for HBV DNA, HBsAg, and hepatitis B e antigen (HBeAg). ...
Whether pregnancy may influence the replication of hepatitis B virus (HBV) remains unknown. The authors aimed to clarify this …
Hepatic decompensation associated with hepatitis B e antigen clearance in chronic type B hepatitis.
Sheen IS, et al. Gastroenterology 1985. PMID 4029555
To examine hepatic decompensation associated with acute exacerbation preceding hepatitis B e antigen clearance in chronic type B hepatitis, 376 patients with chronic hepatitis who were hepatitis B e antigen-positive were prospectively studied for up to 7 yr (mean 25 mo). Among the 165 patients who underwent hepatitis B e antigen clearance, 4 patients experienced hepatic decompensation and one of them eventually developed hepatic encephalopathy and died. ...
To examine hepatic decompensation associated with acute exacerbation preceding hepatitis B e antigen clearance in chron …
Evaluation of reliability and performance of hepatitis B virus-e-antigen assays in tertiary care setting.
Fletcher GJ, et al. J Immunoassay Immunochem 2018. PMID 30362912
Hepatitis B virus-e-antigen (HBeAg) is a viral marker to assess hepatitis B virus (HBV) replication. We have evaluated the reliability of three commonly available HBeAg immunoassays using World Health Organization-International Standard and clinical samples. ...
Hepatitis B virus-e-antigen (HBeAg) is a viral marker to assess hepatitis B virus (HBV) replication. We h
A scoring model predicts hepatitis B e antigen seroconversion in chronic hepatitis B patients treated with nucleos(t)ide analogs: real-world clinical practice.
Geng M, et al. Int J Infect Dis 2017. PMID 28669850 Free article.
AIM: This study developed and validated a non-invasive scoring model to predict 1-year hepatitis B e antigen (HBeAg) seroconversion in response to nucleos(t)ide analog (NA) treatment in NA-naïve patients with HBeAg-positive chronic hepatitis B (CHB). ...
AIM: This study developed and validated a non-invasive scoring model to predict 1-year hepatitis B e antigen (HBeAg) se …
Acute exacerbations of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens. Implications for hepatitis B e antigen seroconversion.
Tsai SL, et al. J Clin Invest 1992. PMID 1729285 Free PMC article.
T cell proliferative responses to hepatitis B virus-encoded envelope antigen (S + preS2 + preS1), recombinant core antigen (HBcAg), and natural hepatitis B e antigen (HBeAg) were examined in 22 HBeAg-positive patients with chronic type B hepatitis and 17 healthy hepatitis B surface antigen (HBsAg) carriers. ...These findings imply that HBcAg/HBeAg-specific T cells play an important role in the exacerbations of chronic hepatitis B and in HBeAg seroconversion. ...
T cell proliferative responses to hepatitis B virus-encoded envelope antigen (S + preS2 + preS1), recombinant core antigen (HB …
Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study.
Bortolotti F, et al. Hepatology 2006. PMID 16496323
Chronic hepatitis B is usually a benign disease in Caucasian children; however, the long-term prognosis remains unsettled. This report describes the results of a 29-year longitudinal study including 99 white children with chronic hepatitis B, mainly acquired horizontally: 91 were hepatitis B e antigen (HBeAg) positive (4 had cirrhosis), and 8 were HBeAg negative at presentation. ...In conclusion, the overall prognosis for chronic hepatitis B in horizontally infected Caucasian children is favorable; however, some patients progress to HCC and HBeAg-negative hepatitis. ...
Chronic hepatitis B is usually a benign disease in Caucasian children; however, the long-term prognosis remains unsettled. Thi …
Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendritic cell generation.
Hatipoglu I, et al. Immunobiology 2014. PMID 25150150
Hepatitis B virus (HBV) continues to be a serious worldwide health problem despite the use of protective HBV vaccines and therapeutic regimens against chronic HBV infection. ...In the present study, we investigated the effect of Hepatitis B virus e antigen (HBeAg) on the generation of bone marrow derived dendritic cells (BMDCs) and the stimulation of plasmacytoid DCs (pDCs). ...
Hepatitis B virus (HBV) continues to be a serious worldwide health problem despite the use of protective HBV vaccines and ther
Use of the cross-reactivity between hepatitis B and non-A, non-B viruses for the identification and detection of non-A, non-B 'e' antigen.
Vitvitski L, et al. J Virol Methods 1980. PMID 6168643
Major antigenic cross-reactivity was demonstrated by immunodiffusion between hepatitis B e/3 and the most common circulating antigen previously reported in the serum of patients with non-A, non-B hepatitis. Since it is the equivalent of an e antigen, this antigen will be hereafter referred to as non-A, non-B/e antigen. Screening with hepatitis B e/3 antigen or anti-hepatitis B e/3 by immunodiffusion may be used as an easy and efficient way to test for non-A, non-B hepatitis in the absence of specific reagents since it detected up to 91% of non-A, non-B antigen and 86% of anti-non-A, non-B/e. ...
Major antigenic cross-reactivity was demonstrated by immunodiffusion between hepatitis B e/3 and the most common circul …
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