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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 14
1991 27
1992 23
1993 36
1994 26
1995 19
1996 29
1997 53
1998 50
1999 51
2000 67
2001 75
2002 77
2003 76
2004 40
2005 21
2006 37
2007 37
2008 34
2009 29
2010 34
2011 40
2012 35
2013 44
2014 38
2015 38
2016 39
2017 40
2018 38
2019 13
2020 0
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1,104 results
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Page 1
Hepatocyte Nuclear Factor 1β-Associated Kidney Disease: More than Renal Cysts and Diabetes.
Verhave JC, et al. J Am Soc Nephrol 2016 - Review. PMID 26319241 Free PMC article.
Hepatocyte nuclear factor 1β (HNF1β)-associated disease is a recently recognized clinical entity with a variable multisystem phenotype. ...The multisystem phenotype is probably attributable to functional promiscuity of the HNF1β transcription factor, involved in the development of the kidney, urogenital tract, pancreas, liver, brain, and parathyroid gland. ...
Hepatocyte nuclear factor 1β (HNF1β)-associated disease is a recently recognized clinical entity with a variable multis
Napsin A, Hepatocyte Nuclear Factor-1-Beta (HNF-1β), Estrogen and Progesterone Receptors Expression in Arias-Stella Reaction.
Ip PPC, et al. Am J Surg Pathol 2019. PMID 30608233
A panel of immunohistochemical markers comprising napsin A, hepatocyte nuclear factor-1-beta (HNF-1β), estrogen and progesterone receptors (ER, PR) has been found useful in confirming a diagnosis of ECCC. ...For napsin A, any cytoplasmic staining was considered positive while only nuclear staining was deemed to be positive for HNF-1β, ER, and PR. ...
A panel of immunohistochemical markers comprising napsin A, hepatocyte nuclear factor-1-beta (HNF-1β), es …
Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.
Aboudehen K, et al. J Am Soc Nephrol 2017. PMID 28507058 Free PMC article.
The transcription factor hepatocyte nuclear factor-1β (HNF-1β) is essential for normal kidney development and function. Inactivation of HNF-1β in mouse kidney tubules leads to early-onset cyst formation and postnatal lethality. ...Treatment of HNF-1β mutant mIMCD3 cells with hypertonic NaCl inhibited the induction of osmoregulated genes, including Nr1h4, which encodes the transcription factor FXR that is required for maximal urinary concentration. ...
The transcription factor hepatocyte nuclear factor-1β (HNF-1β) is essential for normal kidney development and fu …
Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.
Casemayou A, et al. J Am Soc Nephrol 2017. PMID 28739648 Free PMC article.
Peroxisome proliferator-activated receptor γ coactivator 1-α (PPARGC1A), a coactivator of the transcription factor PPAR-γ that controls mitochondrial biogenesis and function, has a pivotal role in the early dysfunction of the proximal tubule and the subsequent renal repair. Here, we evaluated the potential role of hepatocyte nuclear factor-1β (HNF-1β) in regulating PPARGC1A expression in AKI. In mice, endotoxin injection to induce AKI also induced early and transient inflammation and PPARGC1A inhibition, which overlapped with downregulation of the HNF-1β transcriptional network. ...
Peroxisome proliferator-activated receptor γ coactivator 1-α (PPARGC1A), a coactivator of the transcription factor PPAR-γ that …
Involvement of transforming growth factor beta 1 in the transcriptional regulation of nicotinamide N-methyltransferase in clear cell renal cell carcinoma.
Campagna R, et al. Cell Mol Biol (Noisy-le-grand) 2018. PMID 29974846
Signal transducer and activator of transcription 3 (STAT3), interleukin 6 (IL-6), hepatocyte nuclear factor 1 beta (HNF-1β) and transforming growth factor beta 1 (TGF-β1) expression levels were determined in tumor and non tumor samples obtained from 30 patients with ccRCC, using Real-Time PCR. ...
Signal transducer and activator of transcription 3 (STAT3), interleukin 6 (IL-6), hepatocyte nuclear factor 1
[Clinical phenotypes of hepatocyte nuclear factor 1 homeobox b-associated disease].
Wang F, et al. Zhonghua Er Ke Za Zhi 2017. PMID 28881510 Chinese.
Objective: Hepatocyte nuclear factor 1 homeobox b (HNF1B) -associated disease is an autosomal dominant inherited disorder with a variable, multi-systemic phenotype. ...HNF1B heterozygous deletion of exons 1-9 was found in 4 patients and 2 fetuses, and HNF1B heterozygous missense mutation in 1 fetus. ...
Objective: Hepatocyte nuclear factor 1 homeobox b (HNF1B) -associated disease is an autosomal dominant inherited …
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.
Omata M, et al. PLoS One 2016. PMID 27196561 Free PMC article.
In the re-epithelialization process, transcription factor hepatocyte nuclear factor 1, beta (HNF-1β) was identified as a candidate molecule involved in inducing re-epithelialization by means of DNA microarray and biological network analysis. ...
In the re-epithelialization process, transcription factor hepatocyte nuclear factor 1, beta (HNF-1 …
Abnormal splicing of hepatocyte nuclear factor-1 beta in the renal cysts and diabetes syndrome.
Harries LW, et al. Diabetologia 2004. PMID 15085338
AIMS/HYPOTHESIS: Mutations in the hepatocyte nuclear factor-1 beta ( HNF-1 beta) gene result in disorders of renal development, typically involving renal cysts and early-onset diabetes (the RCAD syndrome/ MODY5). ...Sequence analysis of ectopic HNF-1 beta transcripts showed that both IVS2nt+2insT and IVS2nt+1G>T result in the deletion of exon 2 and are predicted to result in premature termination of the HNF-1 beta protein. ...
AIMS/HYPOTHESIS: Mutations in the hepatocyte nuclear factor-1 beta ( HNF-1 beta) gene resul …
The role of hepatocyte nuclear factor 1β in disease and development.
El-Khairi R and Vallier L. Diabetes Obes Metab 2016 - Review. PMID 27615128
Heterozygous mutations in the gene that encodes the transcription factor hepatocyte nuclear factor 1β (HNF1B) result in a multi-system disorder. ...
Heterozygous mutations in the gene that encodes the transcription factor hepatocyte nuclear factor 1β (HNF1B) re …
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