"Hexokinase/genetics"[MeSH] - Search Results

Year	Number of Results
1976	1
1977	1
1978	7
1979	5
1980	3
1981	4
1982	6
1983	7
1984	8
1985	6
1986	3
1987	6
1988	7
1989	10
1990	7
1991	15
1992	13
1993	18
1994	14
1995	27
1996	37
1997	28
1998	21
1999	37
2000	27
2001	25
2002	22
2003	25
2004	21
2005	28
2006	26
2007	26
2008	33
2009	20
2010	24
2011	29
2012	37
2013	48
2014	48
2015	46
2016	52
2017	64
2018	64
2019	73
2020	79
2021	65
2022	60
2023	41
2024	11

1

Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis.

Rho H, Terry AR, Chronis C, Hay N. Rho H, et al. Cell Metab. 2023 Aug 8;35(8):1406-1423.e8. doi: 10.1016/j.cmet.2023.06.013. Epub 2023 Jul 17. Cell Metab. 2023. PMID: 37463576

2

STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2.

Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, Xie J, Zhou Y, Tian M, Zhang C, Sun X, Wang S, Cheng X, Zhang Y, Wei W, Li X, Fu B, Feng P, Wu B, Shu HB, Zhang J. Zhang L, et al. Nat Cell Biol. 2023 Aug;25(8):1208-1222. doi: 10.1038/s41556-023-01185-x. Epub 2023 Jul 13. Nat Cell Biol. 2023. PMID: 37443289

3

Hexokinase 1 cellular localization regulates the metabolic fate of glucose.

De Jesus A, Keyhani-Nejad F, Pusec CM, Goodman L, Geier JA, Stoolman JS, Stanczyk PJ, Nguyen T, Xu K, Suresh KV, Chen Y, Rodriguez AE, Shapiro JS, Chang HC, Chen C, Shah KP, Ben-Sahra I, Layden BT, Chandel NS, Weinberg SE, Ardehali H. De Jesus A, et al. Mol Cell. 2022 Apr 7;82(7):1261-1277.e9. doi: 10.1016/j.molcel.2022.02.028. Epub 2022 Mar 18. Mol Cell. 2022. PMID: 35305311 Free PMC article.

4

Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity.

Hu Y, Cao K, Wang F, Wu W, Mai W, Qiu L, Luo Y, Ge WP, Sun B, Shi L, Zhu J, Zhang J, Wu Z, Xie Y, Duan S, Gao Z. Hu Y, et al. Nat Metab. 2022 Dec;4(12):1756-1774. doi: 10.1038/s42255-022-00707-5. Epub 2022 Dec 19. Nat Metab. 2022. PMID: 36536134

5

HK2: Gatekeeping microglial activity by tuning glucose metabolism and mitochondrial functions.

Fang J, Luo S, Lu Z. Fang J, et al. Mol Cell. 2023 Mar 16;83(6):829-831. doi: 10.1016/j.molcel.2023.02.022. Mol Cell. 2023. PMID: 36931254 Free article.

6

Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease.

Fairley LH, Lai KO, Wong JH, Chong WJ, Vincent AS, D'Agostino G, Wu X, Naik RR, Jayaraman A, Langley SR, Ruedl C, Barron AM. Fairley LH, et al. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2209177120. doi: 10.1073/pnas.2209177120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787364 Free PMC article.

7

CircZBTB44 promotes renal carcinoma progression by stabilizing HK3 mRNA structure.

Li T, Gu Y, Xu B, Kuca K, Zhang J, Wu W. Li T, et al. Mol Cancer. 2023 Apr 27;22(1):77. doi: 10.1186/s12943-023-01771-5. Mol Cancer. 2023. PMID: 37106446 Free PMC article.

8

CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β-Oxidation Pathway.

Li H, Song J, He Y, Liu Y, Liu Z, Sun W, Hu W, Lei QY, Hu X, Chen Z, He X. Li H, et al. Adv Sci (Weinh). 2022 Jul;9(21):e2105126. doi: 10.1002/advs.202105126. Epub 2022 May 23. Adv Sci (Weinh). 2022. PMID: 35603967 Free PMC article.

9

Disrupting Circadian Rhythm via the PER1-HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer.

Wang J, Huang Q, Hu X, Zhang S, Jiang Y, Yao G, Hu K, Xu X, Liang B, Wu Q, Ma Z, Wang Y, Wang C, Wu Z, Rong X, Liao W, Shi M. Wang J, et al. Cancer Res. 2022 Apr 15;82(8):1503-1517. doi: 10.1158/0008-5472.CAN-21-1820. Cancer Res. 2022. PMID: 35255118 Free PMC article.

10

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.

Thomas GE, Egan G, García-Prat L, Botham A, Voisin V, Patel PS, Hoff FW, Chin J, Nachmias B, Kaufmann KB, Khan DH, Hurren R, Wang X, Gronda M, MacLean N, O'Brien C, Singh RP, Jones CL, Harding SM, Raught B, Arruda A, Minden MD, Bader GD, Hakem R, Kornblau S, Dick JE, Schimmer AD. Thomas GE, et al. Nat Cell Biol. 2022 Jun;24(6):872-884. doi: 10.1038/s41556-022-00925-9. Epub 2022 Jun 6. Nat Cell Biol. 2022. PMID: 35668135 Free PMC article.

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