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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 1
1990 1
1991 2
1992 3
1993 3
1994 35
1995 115
1996 179
1997 249
1998 319
1999 334
2000 389
2001 392
2002 448
2003 433
2004 406
2005 448
2006 559
2007 558
2008 547
2009 510
2010 557
2011 648
2012 619
2013 676
2014 641
2015 677
2016 676
2017 633
2018 630
2019 322
2020 4
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10,919 results
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Page 1
The genetics and the molecular functions of the PREP1 homeodomain transcription factor.
Purushothaman D and Blasi F. Int J Dev Biol 2018 - Review. PMID 30604851 Free article.
Prep1 (pKnox1) is a homeodomain transcription factor of the TALE superclass whose members can act as co-factors of Hox. Prep1 is essential for embryogenesis, but in the adult it also acts as a tumor suppressor. ...
Prep1 (pKnox1) is a homeodomain transcription factor of the TALE superclass whose members can act as co-factors of Hox. Prep1 is esse …
DUX-family transcription factors regulate zygotic genome activation in placental mammals
De Iaco A, et al. Nat Genet 2017. PMID 28459456 Free PMC article.
Second, both orthologous proteins bind the promoters of ZGA-associated genes and activate their transcription. Third, Dux knockout in mouse embryonic stem cells (mESCs) prevents the cells from cycling through a 2-cell-like state. ...We conclude that DUX-family proteins are key inducers of zygotic genome activation in placental mammals....
Second, both orthologous proteins bind the promoters of ZGA-associated genes and activate their transcription. Third, Dux knockout in …
Conservation and innovation in the DUX4-family gene network
Whiddon JL, et al. Nat Genet 2017. PMID 28459454 Free PMC article.
Thus, the ancestral DUX4-regulated genes are characteristic of cleavage-stage embryos and are driven by conventional promoters, whereas divergence of the DUX4 and DUX homeodomains correlates with retrotransposon specificity. ...
Thus, the ancestral DUX4-regulated genes are characteristic of cleavage-stage embryos and are driven by conventional promoters, whereas dive …
Did homeodomain proteins duplicate before the origin of angiosperms, fungi, and metazoa?
Bharathan G, et al. Proc Natl Acad Sci U S A 1997. PMID 9391098 Free PMC article.
Homeodomain proteins are transcription factors that play a critical role in early development in eukaryotes. These proteins previously have been classified into numerous subgroups whose phylogenetic relationships are unclear. Our phylogenetic analysis of representative eukaryotic sequences suggests that there are two major groups of homeodomain proteins, each containing sequences from angiosperms, metazoa, and fungi. ...
Homeodomain proteins are transcription factors that play a critical role in early development in eukaryotes. These proteins
Putative homeodomain proteins identified in prokaryotes based on pattern and sequence similarity.
Kant S, et al. Biochem Biophys Res Commun 2002. PMID 12437974
A putative homeodomain has been identified in eubacterial genomes, which include several pathogens. The domain is related in sequence to homeodomain, a component specific to transcription factors and playing a very important role in eukaryotes such as controlling the developmental processes of the organism. The putative homeodomain has been characterized utilizing the eukaryotic homeodomain protein sequence signature present in PROSITE as well as the sequence similarity search using BLAST suite for different eubacterial genomes. ...
A putative homeodomain has been identified in eubacterial genomes, which include several pathogens. The domain is related in sequence …
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