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1982 42
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2010 568
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2012 708
2013 738
2014 757
2015 767
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18,349 results

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Page 1
Huntington's disease: a clinical review.
McColgan P, Tabrizi SJ. McColgan P, et al. Eur J Neurol. 2018 Jan;25(1):24-34. doi: 10.1111/ene.13413. Epub 2017 Sep 22. Eur J Neurol. 2018. PMID: 28817209 Review.
Huntington's disease (HD) is a fully penetrant neurodegenerative disease caused by a dominantly inherited CAG trinucleotide repeat expansion in the huntingtin gene on chromosome 4. ...
Huntington's disease (HD) is a fully penetrant neurodegenerative disease caused by a dominantly inherited CAG trinucleo
Huntington's disease clinical trials update: March 2025.
Farag M, Tabrizi SJ, Wild EJ. Farag M, et al. J Huntingtons Dis. 2025 May;14(2):191-206. doi: 10.1177/18796397251337000. Epub 2025 Apr 30. J Huntingtons Dis. 2025. PMID: 40302443 Free PMC article. Review.
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing phase I clinical trial of ALN-HTT02 from Alynlam Pharmaceuticals. ...Finally, we provide a comprehensive listing of all currently registered and ongoing clinical tria …
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing phase I clinical trial of …
Gene targeting techniques for Huntington's disease.
Fields E, Vaughan E, Tripu D, Lim I, Shrout K, Conway J, Salib N, Lee Y, Dhamsania A, Jacobsen M, Woo A, Xue H, Cao K. Fields E, et al. Ageing Res Rev. 2021 Sep;70:101385. doi: 10.1016/j.arr.2021.101385. Epub 2021 Jun 5. Ageing Res Rev. 2021. PMID: 34098113 Free PMC article. Review.
Huntington's disease (HD) is an autosomal neurodegenerative disorder caused by extended trinucleotide CAG repetition in the HTT gene. ...
Huntington's disease (HD) is an autosomal neurodegenerative disorder caused by extended trinucleotide CAG repetition in
Huntington's Disease: A Clinical Review.
Andhale R, Shrivastava D. Andhale R, et al. Cureus. 2022 Aug 27;14(8):e28484. doi: 10.7759/cureus.28484. eCollection 2022 Aug. Cureus. 2022. PMID: 36176885 Free PMC article. Review.
The Huntington's gene on chromosome 4 has a dominantly inherited CAG trinucleotide repeat expansion, ultimately resulting in Huntington's disease (HD), a completely penetrant neurological condition. The frequency is 10-100 times higher in the population desce …
The Huntington's gene on chromosome 4 has a dominantly inherited CAG trinucleotide repeat expansion, ultimately resulting in Huntington
Huntington's Disease: New Frontiers in Therapeutics.
Pan L, Feigin A. Pan L, et al. Curr Neurol Neurosci Rep. 2021 Feb 14;21(3):10. doi: 10.1007/s11910-021-01093-3. Curr Neurol Neurosci Rep. 2021. PMID: 33586075 Review.
PURPOSE OF REVIEW: This article describes and discusses new potential disease-modifying therapies for Huntington's disease that are currently in human clinical trials as well as promising new therapies in preclinical development. RECENT FINDINGS: Multiple pot …
PURPOSE OF REVIEW: This article describes and discusses new potential disease-modifying therapies for Huntington's disease
Huntington's disease.
Kent A. Kent A. Nurs Stand. 2004 Apr 21-27;18(32):45-51; quiz 52-3. doi: 10.7748/ns2004.04.18.32.45.c3596. Nurs Stand. 2004. PMID: 15132037 Review.
Huntington's disease is a complex degenerative disorder that affects the central nervous system. ...This article discusses the cause and symptoms, explains the method of diagnosis and outlines the role of the nurse in caring for patients with Huntington
Huntington's disease is a complex degenerative disorder that affects the central nervous system. ...This article discus
A developmental component to Huntington's disease.
Ratié L, Humbert S. Ratié L, et al. Rev Neurol (Paris). 2024 May;180(5):357-362. doi: 10.1016/j.neurol.2024.04.001. Epub 2024 Apr 12. Rev Neurol (Paris). 2024. PMID: 38614929 Free article. Review.
Huntington's disease is a dominantly inherited disorder characterized by the dysfunction and death of cortical and striatal neurons. Striatal degeneration in Huntington's disease is due, at least in part, to defective cortical signalling
Huntington's disease is a dominantly inherited disorder characterized by the dysfunction and death of cortical and stri
Huntington's Disease Clinical Trials Corner: January 2019.
Rodrigues FB, Quinn L, Wild EJ. Rodrigues FB, et al. J Huntingtons Dis. 2019;8(1):115-125. doi: 10.3233/JHD-190001. J Huntingtons Dis. 2019. PMID: 30776019 Review.
In this edition of the Huntington's Disease Clinical Trials Corner we expand on the GENERATION-HD1 and PACE-HD trials, and we list all currently registered and ongoing clinical trials in Huntington's disease....
In this edition of the Huntington's Disease Clinical Trials Corner we expand on the GENERATION-HD1 and PACE-HD trials, …
Molecular Pathophysiological Mechanisms in Huntington's Disease.
Jurcau A. Jurcau A. Biomedicines. 2022 Jun 17;10(6):1432. doi: 10.3390/biomedicines10061432. Biomedicines. 2022. PMID: 35740453 Free PMC article. Review.
Huntington's disease is an inherited neurodegenerative disease described 150 years ago by George Huntington. ...However, due to the ubiquitous presence of huntingtin, astrocytes are also dysfunctional, and neuroinflammation may additionally contribute to H
Huntington's disease is an inherited neurodegenerative disease described 150 years ago by George Huntington. ...However
Huntington's Disease Drug Development: A Phase 3 Pipeline Analysis.
Van de Roovaart HJ, Nguyen N, Veenstra TD. Van de Roovaart HJ, et al. Pharmaceuticals (Basel). 2023 Oct 24;16(11):1513. doi: 10.3390/ph16111513. Pharmaceuticals (Basel). 2023. PMID: 38004378 Free PMC article. Review.
Huntington's Disease (HD) is a severely debilitating neurodegenerative disorder in which sufferers exhibit different combinations of movement disorders, dementia, and behavioral or psychiatric abnormalities. ...
Huntington's Disease (HD) is a severely debilitating neurodegenerative disorder in which sufferers exhibit different co
18,349 results
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