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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1965 3
1966 1
1967 1
1968 3
1969 3
1970 4
1971 5
1972 4
1973 8
1974 6
1975 8
1976 7
1977 7
1978 7
1979 6
1980 11
1981 14
1982 5
1983 10
1984 20
1985 22
1986 18
1987 20
1988 15
1989 11
1990 19
1991 21
1992 22
1993 23
1994 23
1995 25
1996 28
1997 30
1998 46
1999 54
2000 60
2001 58
2002 67
2003 63
2004 79
2005 90
2006 111
2007 117
2008 103
2009 98
2010 159
2011 165
2012 199
2013 175
2014 163
2015 169
2016 146
2017 133
2018 169
2019 47
2020 0
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2,583 results
Results by year
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Page 1
The Neuropathology of Huntington's Disease.
Waldvogel HJ, et al. Curr Top Behav Neurosci 2015 - Review. PMID 25300927
The most important new findings in Huntington's disease pathology is the highly variable nature of the degeneration in the brain. Most interestingly, this variable pattern of pathology appears to reflect the highly variable symptomatology of cases with Huntington's disease even among cases possessing the same number of CAG repeats....
The most important new findings in Huntington's disease pathology is the highly variable nature of the degeneration in the brain. Mos …
Huntington disease: natural history, biomarkers and prospects for therapeutics.
Ross CA, et al. Nat Rev Neurol 2014 - Review. PMID 24614516
Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is caused by a single genetic mutation and is amenable to predictive genetic testing, with estimation of years to predicted onset, enabling the entire range of disease natural history to be studied. ...
Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is caused by a single genetic mutation and is a
Huntington's disease: Neuropsychiatric manifestations of Huntington's disease.
Goh AM, et al. Australas Psychiatry 2018 - Review. PMID 30012004
OBJECTIVES: Huntington's disease (HD) is a profoundly incapacitating, and ultimately fatal, neurodegenerative disease. HD is presently incurable, so the current goal is to allow affected individuals to live as well as possible with the illness, to maximise functional independence and quality of life for the person with HD, their carers and family members. ...
OBJECTIVES: Huntington's disease (HD) is a profoundly incapacitating, and ultimately fatal, neurodegenerative disease. HD is presentl …
Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.
Khakh BS, et al. Trends Neurosci 2017 - Review. PMID 28578789 Free PMC article.
Here, we summarize our current understanding of astrocytes and Huntington's disease (HD), with a focus on correlative and causative dysfunctions of ion homeostasis, calcium signaling, and neurotransmitter clearance, as well as on the use of transplanted astrocytes to produce therapeutic benefit in mouse models of HD. ...
Here, we summarize our current understanding of astrocytes and Huntington's disease (HD), with a focus on correlative and causative d …
Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation.
Mehta SR, et al. Cell Rep 2018. PMID 30355486 Free article.
Huntington's disease (HD) is a neurodegenerative disease caused by an expanded CAG repeat in the Huntingtin (HTT) gene. Induced pluripotent stem cell (iPSC) models of HD provide an opportunity to study the mechanisms underlying disease pathology in disease-relevant patient tissues. ...
Huntington's disease (HD) is a neurodegenerative disease caused by an expanded CAG repeat in the Huntingtin (HTT) gene. Induced pluri
Structural Magnetic Resonance Imaging in Huntington's Disease.
Wilson H, et al. Int Rev Neurobiol 2018 - Review. PMID 30409258
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by expansion of the CAG repeat in the huntingtin gene. ...
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by expansion of the CAG repeat in the huntingti
Neurocardiovascular pathology in pre-manifest and early-stage Huntington's disease.
Bellosta Diago E, et al. Eur J Neurol 2018 - Clinical Trial. PMID 29537687
BACKGROUND AND PURPOSE: Cardiovascular events are a major cause of early death in the Huntington's disease (HD) population. Dysautonomia as well as deterioration of circadian rhythms can be detected early in the disease progression and can have profound effects on cardiac health. ...
BACKGROUND AND PURPOSE: Cardiovascular events are a major cause of early death in the Huntington's disease (HD) population. Dysautono …
Overlap between age-at-onset and disease-progression determinants in Huntington disease.
Aziz NA, et al. Neurology 2018. PMID 29743208 Free PMC article.
OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as those that govern disease progression. ...
OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determ …
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