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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1949 2
1950 4
1951 3
1952 2
1953 4
1954 2
1955 3
1956 6
1957 11
1958 11
1959 14
1960 16
1961 27
1962 43
1963 66
1964 160
1965 147
1966 158
1967 213
1968 260
1969 244
1970 255
1971 298
1972 307
1973 304
1974 308
1975 273
1976 231
1977 250
1978 198
1979 243
1980 255
1981 210
1982 215
1983 184
1984 197
1985 202
1986 234
1987 187
1988 172
1989 173
1990 177
1991 208
1992 187
1993 189
1994 198
1995 148
1996 156
1997 167
1998 155
1999 149
2000 137
2001 139
2002 161
2003 151
2004 157
2005 151
2006 170
2007 192
2008 152
2009 193
2010 203
2011 203
2012 185
2013 188
2014 182
2015 165
2016 164
2017 123
2018 138
2019 67
2020 2
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10,692 results
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Page 1
Hydroxyproline: A Potential Biochemical Marker and Its Role in the Pathogenesis of Different Diseases.
Srivastava AK, et al. Curr Protein Pept Sci 2016 - Review. PMID 26916157
Various abnormalities in hydroxyproline metabolism have been shown to play key roles in the pathophysiology and pathogenesis of different diseases. ...The review concludes with an outlook on the scope and challenges in the clinical implementation of hydroxyproline as a biomarker....
Various abnormalities in hydroxyproline metabolism have been shown to play key roles in the pathophysiology and pathogenesis of diffe …
Roles of dietary glycine, proline, and hydroxyproline in collagen synthesis and animal growth.
Li P and Wu G. Amino Acids 2018 - Review. PMID 28929384
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of proteins in animals. ...
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of …
Incorporation of hydroxyproline in bacterial collagen from Streptococcus pyogenes.
Peng YY, et al. Acta Biomater 2018. PMID 30218779
Another difference is the lack of aggregation, and certain vertebrate collagen binding domains that can be introduced into the bacterial sequence lack full function when hydroxyproline is absent. ...Unlike animal collagens, they are stable without the need for inclusion of a secondary modification system for hydroxyproline incorporation. ...
Another difference is the lack of aggregation, and certain vertebrate collagen binding domains that can be introduced into the bacterial seq …
Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria.
Fargue S, et al. J Am Soc Nephrol 2018. PMID 29588429 Free PMC article.
Hydroxyproline (Hyp) metabolism results in the formation of oxalate and glycolate. However, the relative contribution of Hyp metabolism to endogenous oxalate and glycolate synthesis is not known.Methods To define this contribution, we performed primed, continuous, intravenous infusions of the stable isotope [(15)N,(13)C(5)]-Hyp in nine healthy subjects and 19 individuals with PH and quantified the levels of urinary (13)C(2)-oxalate and (13)C(2)-glycolate formed using ion chromatography coupled to mass detection.Results The total urinary oxalate-to-creatinine ratio during the infusion was 73.1, 70.8, 47.0, and 10.6 mg oxalate/g creatinine in subjects with PH1, PH2, and PH3 and controls, respectively. ...
Hydroxyproline (Hyp) metabolism results in the formation of oxalate and glycolate. However, the relative contribution of Hyp metaboli
Hydroxyproline Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice: Involvment of the NF-κB Signaling and Oxidative Stress.
Ji Y, et al. Mol Nutr Food Res 2018. PMID 30184329
The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, attenuates dextran sulfate sodium (DSS)-induced colitis in mice. ...
The aim of the present study is to test the hypothesis that hydroxyproline (Hyp), an amino acid with an antioxidative property, atten …
Measurement of elastin, collagen, and total protein levels in tissues
Stoilov I, et al. Methods Cell Biol 2018. PMID 29310774
Marker amino acids unique to each protein (desmosine for elastin and hydroxyproline for collagen) are then quantified. Total protein content, useful as a denominator for data normalization, can also be measured from a portion of the hydrolysate using an assay for free amino groups. ...
Marker amino acids unique to each protein (desmosine for elastin and hydroxyproline for collagen) are then quantified. Total protein …
Mechanical elasticity of proline-rich and hydroxyproline-rich collagen-like triple-helices studied using steered molecular dynamics.
Ghanaeian A and Soheilifard R. J Mech Behav Biomed Mater 2018. PMID 29986285
Proline and hydroxyproline are the most abundant residues at the X and Y sites of collagen repetitive motives, respectively. ...Results showed a higher stiffness and Young's moduli of the proline-rich collagens compared to the hydroxyproline-rich collagens. ...
Proline and hydroxyproline are the most abundant residues at the X and Y sites of collagen repetitive motives, respectively. ...Resul …
Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension
Simko F, et al. Int J Mol Sci 2018. PMID 30282928 Free PMC article.
L-NAME administration increased systolic blood pressure (SBP) and left ventricular (LV) weight, enhanced hydroxyproline concentration in the LV, and deteriorated the systolic and diastolic LV function. ...
L-NAME administration increased systolic blood pressure (SBP) and left ventricular (LV) weight, enhanced hydroxyproline concentration …
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