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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1945 72
1946 233
1947 300
1948 330
1949 295
1950 503
1951 676
1952 752
1953 772
1954 898
1955 943
1956 892
1957 775
1958 691
1959 632
1960 703
1961 751
1962 820
1963 1082
1964 1576
1965 1228
1966 1062
1967 1220
1968 1380
1969 1771
1970 1868
1971 2620
1972 2967
1973 3261
1974 3327
1975 3250
1976 3109
1977 2885
1978 2998
1979 3161
1980 2738
1981 2511
1982 2731
1983 3131
1984 3329
1985 3456
1986 3301
1987 3900
1988 3629
1989 3874
1990 4030
1991 4168
1992 4310
1993 4443
1994 4370
1995 4425
1996 4432
1997 4635
1998 4626
1999 5082
2000 5152
2001 5554
2002 5657
2003 6113
2004 6329
2005 6665
2006 6731
2007 6996
2008 7184
2009 7390
2010 7904
2011 8759
2012 8688
2013 9273
2014 9764
2015 10346
2016 10698
2017 11294
2018 11792
2019 5205
2020 123
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270,103 results
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Page 1
Cancer immunotherapy: harnessing the immune system to battle cancer.
Yang Y. J Clin Invest 2015 - Review. PMID 26325031 Free PMC article.
The recent clinical successes of immune checkpoint blockade and chimeric antigen receptor T cell therapies represent a turning point in cancer immunotherapy. ...The Reviews in this Review Series focus on current developments in cancer immunotherapy, highlight recent advances in our understanding of basic aspects of tumor immunology, and suggest how these insights can lead to the development of new immunotherapeutic strategies....
The recent clinical successes of immune checkpoint blockade and chimeric antigen receptor T cell therapies represent a turning point in canc …
Immunotherapy for metastatic breast cancer.
Sugie T. Chin Clin Oncol 2018 - Review. PMID 30056730 Free article.
Among molecular subtypes, single agent cancer immunotherapy showed the most promising results in TNBC. The development of immuno-oncology combinations is required to increase the clinical benefit of immunotherapy against breast cancer. Response to the immunotherapy depends on the dynamic interaction between tumor and immune cells in the tumor microenvironment. ...
Among molecular subtypes, single agent cancer immunotherapy showed the most promising results in TNBC. The development of immuno-onco …
[Cancer immunotherapy: Rational and recent breakthroughs].
Granier C, et al. Rev Med Interne 2016 - Review. PMID 27370898 French.
Cancer immunotherapy has occupied a marginal therapeutic option in cancer despite strong arguments documenting the role of the immune system in controlling the proliferation of cancers. The recent success of immunotherapy results from a change in the past paradigm. From now on, the goal is not only to activate the immune system against tumor, but also to take account of the immunosuppressive tumor microenvironment Among these mechanisms, negative costimulatory molecules (CTLA-4, PD-1, etc.) expressed by T cells in the tumor could explain their lack of effectiveness in inhibiting tumor growth. ...
Cancer immunotherapy has occupied a marginal therapeutic option in cancer despite strong arguments documenting the role of the immune …
Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.
Puzanov I, et al. J Immunother Cancer 2017. PMID 29162153 Free PMC article.
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse events (irAEs). ...The Society for Immunotherapy of Cancer (SITC) established a multidisciplinary Toxicity Management Working Group, which met for a full-day workshop to develop recommendations to standardize management of irAEs. ...
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely …
Cancer immunotherapy: accomplishments to date and future promise.
Helmy KY, et al. Ther Deliv 2013 - Review. PMID 24116914
Immunotherapies for cancer offer the promise of the specificity and memory of the immune system against malignant cells to achieve durable cure with minimal toxicity. ...Here, we review the history of immunotherapies for cancer and discuss existing and emerging immunotherapy technologies that hope to translate the promise of immunotherapy into clinical reality....
Immunotherapies for cancer offer the promise of the specificity and memory of the immune system against malignant cells to achieve du
New developments in immunotherapy for pediatric solid tumors.
Schultz LM, et al. Curr Opin Pediatr 2018 - Review. PMID 29189429
PURPOSE OF REVIEW: Building upon preclinical advances, we are uncovering immunotherapy strategies that are translating into improved outcomes in tumor subsets. ...SUMMARY: Pediatric immunotherapy remains at early stages of translation, yet we anticipate that with advanced technology, we will achieve widespread, efficacious use of immunotherapy for pediatric solid tumors....
PURPOSE OF REVIEW: Building upon preclinical advances, we are uncovering immunotherapy strategies that are translating into improved …
Advances in cancer immunotherapy 2019 - latest trends.
Kruger S, et al. J Exp Clin Cancer Res 2019 - Review. PMID 31217020 Free PMC article.
Immunotherapy has become an established pillar of cancer treatment improving the prognosis of many patients with a broad variety of hematological and solid malignancies. ...Regarding cellular immunotherapy, recent studies confirmed safety and efficacy of CAR T cells in larger cohorts of patients with acute lymphoblastic leukemia or diffuse large B cell lymphoma. ...
Immunotherapy has become an established pillar of cancer treatment improving the prognosis of many patients with a broad variety of h
The role of immunotherapy in in vitro fertilization: a guideline.
Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org and Practice Committee of the American Society for Reproductive Medicine . Fertil Steril 2018. PMID 30098685
Adjuvant immunotherapy treatments in in vitro fertilization (IVF) aim to improve the outcome of assisted reproductive technology (ART) in both the general ART population as well as subgroups such as patients with recurrent miscarriage or implantation failure. ...Immunotherapies reviewed in the present document are either not associated with improved live-birth outcome in IVF or have been insufficiently studied to make definitive recommendations....
Adjuvant immunotherapy treatments in in vitro fertilization (IVF) aim to improve the outcome of assisted reproductive technology (ART …
Endocrine side effects of cancer immunotherapy.
Cukier P, et al. Endocr Relat Cancer 2017 - Review. PMID 29025857
We discuss the incidence, clinical manifestations, diagnosis and management of immune-related endocrinopathies in this highly complex context of oncological patients in need of immunotherapies....
We discuss the incidence, clinical manifestations, diagnosis and management of immune-related endocrinopathies in this highly complex contex …
New developments in immunotherapy for pediatric leukemia.
Foster JB and Maude SL. Curr Opin Pediatr 2018 - Review. PMID 29176353
PURPOSE OF REVIEW: Immunotherapy for the treatment of cancer has advanced at a tremendous pace over the last decade. In this review, we provide an overview of recent progress in immunotherapy for the treatment of leukemia, focusing on antibody-drug conjugates (ADC), bi-specific T-cell engagers (BiTE), and chimeric antigen receptor (CAR) T cells. ...SUMMARY: The use of immunotherapy for leukemia has been successful in creating durable remissions for multiply relapsed and refractory patients who previously had little chance of cure. ...
PURPOSE OF REVIEW: Immunotherapy for the treatment of cancer has advanced at a tremendous pace over the last decade. In this review, …
270,103 results
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