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Quoted phrase not found in phrase index: "Increased proportion of CD4+CD25+ regulatory T cells"
Page 1
T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer.
Ni H, Zhang H, Li L, Huang H, Guo H, Zhang L, Li C, Xu JX, Nie CP, Li K, Zhang X, Xia X, Li J. Ni H, et al. J Immunother Cancer. 2022 Sep;10(9):e005151. doi: 10.1136/jitc-2022-005151. J Immunother Cancer. 2022. PMID: 36126994 Free PMC article.
The impact of T-EXO on T cell differentiation was tested in in vitro cell culture. RESULTS: Increased STING, CCL22 level, FOXP3(+) cells but decreased CD8(+) cells in tumor tissues predicted poor survival. Tumor-bearing CD4-Cre-STING(flox/flox) (TKO) mice displayed …
The impact of T-EXO on T cell differentiation was tested in in vitro cell culture. RESULTS: Increased STING, CCL22 level, FOXP3(+) ce …
SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma.
Lin L, Chen S, Wang H, Gao B, Kallakury B, Bhuvaneshwar K, Cahn K, Gusev Y, Wang X, Wu Y, Marshall JL, Zhi X, He AR. Lin L, et al. Theranostics. 2021 Feb 20;11(9):4232-4250. doi: 10.7150/thno.49819. eCollection 2021. Theranostics. 2021. PMID: 33754058 Free PMC article.
Heterozygous loss of SPTBN1 (Sptbn1(+/-) ) in mice markedly upregulated hepatic expression of IL-1alpha, IL-1beta and IL-6, and elevated the proportion of myeloid-derived suppressor cells (MDSCs) and CD4(+)CD25(+)Foxp3(+) regulatory T cells (Foxp3(+)Tr …
Heterozygous loss of SPTBN1 (Sptbn1(+/-) ) in mice markedly upregulated hepatic expression of IL-1alpha, IL-1beta and IL-6, and elevated the …
Modulation of regulatory T cells by natural products in cancer.
Bahrami A, Fereidouni M, Pirro M, Bianconi V, Sahebkar A. Bahrami A, et al. Cancer Lett. 2019 Sep 10;459:72-85. doi: 10.1016/j.canlet.2019.06.001. Epub 2019 Jun 6. Cancer Lett. 2019. PMID: 31176742 Review.
Among the elements of immune tolerance orchestra, the CD4(+)CD25 + forkhead box protein3+ (Foxp3+) regulatory T cells (Tregs) have a great importance. Moreover, increased Treg populations and, particularly, reduced proportions of effector T cell …
Among the elements of immune tolerance orchestra, the CD4(+)CD25 + forkhead box protein3+ (Foxp3+) regulatory T cells ( …
Effect of sevoflurane on CD4+CD25+FOXP3+ regulatory T cells in patients with gastric cancer undergoing radical surgery.
Yong F, Wang H, Li C, Liu W, Wang Z, Jia H. Yong F, et al. Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):214-220. doi: 10.14715/cmb/2023.69.8.33. Cell Mol Biol (Noisy-le-grand). 2023. PMID: 37715379
In this study, the proportion of CD4+CD25+FOXP3+ regulatory T (Treg) cells in CD4+ T cells in the peripheral blood of gastric cancer patients before anesthesia induction (T1), after surgery (T2) and the first day after surgery (T3) was studied to explo …
In this study, the proportion of CD4+CD25+FOXP3+ regulatory T (Treg) cells in CD4+ T cells in the peripheral blo …
Increased activated regulatory T cells proportion correlate with the severity of idiopathic pulmonary fibrosis.
Hou Z, Ye Q, Qiu M, Hao Y, Han J, Zeng H. Hou Z, et al. Respir Res. 2017 Sep 8;18(1):170. doi: 10.1186/s12931-017-0653-3. Respir Res. 2017. PMID: 28886713 Free PMC article.
RESULTS: In peripheral blood, no difference was found in CD4(+)CD25(+)Foxp3(+) Treg percentages among patients with IPF, pSS-IP, or HCs. However, activated Treg (aTreg) fractions among CD4(+) T cells increased significantly in IPF compared with pSS-IP or HCs. …
RESULTS: In peripheral blood, no difference was found in CD4(+)CD25(+)Foxp3(+) Treg percentages among patients with IPF, pSS-I …
CD4+CD25-Foxp3+ T cells: a marker for lupus nephritis?
Bonelli M, Göschl L, Blüml S, Karonitsch T, Steiner CW, Steiner G, Smolen JS, Scheinecker C. Bonelli M, et al. Arthritis Res Ther. 2014 Apr 28;16(2):R104. doi: 10.1186/ar4553. Arthritis Res Ther. 2014. PMID: 24774748 Free PMC article.
RESULTS: CD4+CD25-Foxp3+ T cells were significantly increased in active SLE patients and the majority expressed Helios. Detailed analysis of this patient cohort revealed increased proportions of CD4+CD25-Foxp3+ T cells in SLE patie …
RESULTS: CD4+CD25-Foxp3+ T cells were significantly increased in active SLE patients and the majority expressed Helios. …
Single-Cell Sequencing Reveals the Transcriptome and TCR Characteristics of pTregs and in vitro Expanded iTregs.
Hui Z, Zhang J, Zheng Y, Yang L, Yu W, An Y, Wei F, Ren X. Hui Z, et al. Front Immunol. 2021 Mar 31;12:619932. doi: 10.3389/fimmu.2021.619932. eCollection 2021. Front Immunol. 2021. PMID: 33868236 Free PMC article.
Treg cells with satisfactory phenotype and function were successfully expanded from CD4+CD25+ cells in patients with colorectal cancer. The median expansion fold was 75 (range, 20-105-fold), and >90.0% of the harvest cells were CD4+CD25+CD127(dim/-) …
Treg cells with satisfactory phenotype and function were successfully expanded from CD4+CD25+ cells in patients with colorecta …
Circulating Immune Cells Predict Prognosis and Clinical Response to Chemotherapy in Cholangiocarcinoma.
Shi H, Li Z, Zhu M. Shi H, et al. Curr Med Chem. 2025;32(3):595-607. doi: 10.2174/0109298673296618240424095548. Curr Med Chem. 2025. PMID: 38698750
Meanwhile, we assessed the implications of lymphocyte subsets as predictors of chemotherapy outcomes and overall survival (OS). RESULTS: The proportion of total lymphocytes decreased, while the percentages of activated T cells as well as CD4(+)CD25(+) …
Meanwhile, we assessed the implications of lymphocyte subsets as predictors of chemotherapy outcomes and overall survival (OS). RESUL …
Function of regulatory T-cells improved by dexamethasone in Graves' disease.
Hu Y, Tian W, Zhang LL, Liu H, Yin GP, He BS, Mao XM. Hu Y, et al. Eur J Endocrinol. 2012 Apr;166(4):641-6. doi: 10.1530/EJE-11-0879. Epub 2012 Jan 4. Eur J Endocrinol. 2012. PMID: 22219499
CD4(+)CD25(-)/CD4(+)CD25(+)T cells were isolated by immunomagnetic selection and DEX was co-cultured with PBMCs or isolated T-cells for 72 h. ...Although the proportion of Treg cells and FOXP3 mRNA expression in PBMCs did not increase, th …
CD4(+)CD25(-)/CD4(+)CD25(+)T cells were isolated by immunomagnetic selection and DEX was co-cultured with PBMCs …
Circulating CD4+CD25+ regulatory T cells in patients with pancreatic cancer.
Yamamoto T, Yanagimoto H, Satoi S, Toyokawa H, Hirooka S, Yamaki S, Yui R, Yamao J, Kim S, Kwon AH. Yamamoto T, et al. Pancreas. 2012 Apr;41(3):409-15. doi: 10.1097/MPA.0b013e3182373a66. Pancreas. 2012. PMID: 22158072
Their peripheral blood mononuclear cells were evaluated to determine the proportion of CD4CD25 (FoxP3) T cells, as a percentage of the total CD4 cells, by flow cytometric analysis. ...The immunological monitoring of Treg may be useful to predict the prognosis …
Their peripheral blood mononuclear cells were evaluated to determine the proportion of CD4CD25 (FoxP3) T cells, as a percentage of th …
58 results