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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1960 4
1967 1
1974 21
1975 56
1976 46
1977 41
1978 45
1979 57
1980 61
1981 70
1982 93
1983 92
1984 102
1985 132
1986 108
1987 113
1988 134
1989 114
1990 124
1991 133
1992 134
1993 163
1994 142
1995 150
1996 177
1997 231
1998 242
1999 252
2000 332
2001 352
2002 356
2003 417
2004 472
2005 501
2006 592
2007 616
2008 688
2009 806
2010 850
2011 865
2012 918
2013 827
2014 820
2015 943
2016 762
2017 776
2018 697
2019 307
2020 2
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14,469 results
Results by year
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Page 1
Origin and physiological roles of inflammation.
Medzhitov R. Nature 2008 - Review. PMID 18650913
Inflammation underlies a wide variety of physiological and pathological processes. Although the pathological aspects of many types of inflammation are well appreciated, their physiological functions are mostly unknown. The classic instigators of inflammation - infection and tissue injury - are at one end of a large range of adverse conditions that induce inflammation, and they trigger the recruitment of leukocytes and plasma proteins to the affected tissue site. ...
Inflammation underlies a wide variety of physiological and pathological processes. Although the pathological aspects of many types of
Lipid Mediators in Inflammation.
Bennett M and Gilroy DW. Microbiol Spectr 2016 - Review. PMID 27837747
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. ...This review will collate the bioactive lipid research to date and summarize the major pathways involved in their biosynthesis and role in inflammation. ...
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation
Nonresolving inflammation.
Nathan C and Ding A. Cell 2010 - Review. PMID 20303877 Free article.
Nonresolving inflammation is a major driver of disease. Perpetuation of inflammation is an inherent risk because inflammation can damage tissue and necrosis can provoke inflammation. ...Cells like macrophages switch phenotypes, secreted molecules like reactive oxygen intermediates switch impact from pro- to anti-inflammatory, and additional mediators of resolution arise, including proteins, lipids, and gasses. ...
Nonresolving inflammation is a major driver of disease. Perpetuation of inflammation is an inherent risk because inflammati
Inflammation in atherosclerosis.
Taleb S. Arch Cardiovasc Dis 2016 - Review. PMID 27595467 Free article.
Bioactive Lipids and Chronic Inflammation: Managing the Fire Within.
Chiurchiù V, et al. Front Immunol 2018 - Review. PMID 29434586 Free PMC article.
However, persistent and uncontrolled immune reactions act as a wildfire that promote chronic inflammation, unresolved tissue damage and, eventually, chronic diseases. A wide network of soluble mediators, among which endogenous bioactive lipids, governs all immune processes. They are secreted by basically all cells involved in inflammatory processes and constitute the crucial infrastructure that triggers, coordinates and confines inflammatory mechanisms. ...
However, persistent and uncontrolled immune reactions act as a wildfire that promote chronic inflammation, unresolved tissue damage a …
Chemokines and immunity
Palomino DC and Marti LC. Einstein (Sao Paulo) 2015 - Review. PMID 26466066 Free PMC article.
The physiologic importance of this family of mediators is resulting from their specificity - members of the chemokine family induce recruitment of well-defined leukocyte subsets. ...This review discusses the potential role of chemokines in inflammation focusing on the two best-characterized chemokines: monocyte chemoattractant protein-1, a CC chemokine, and interleukin-8, a member of the CXC chemokine sub-family....
The physiologic importance of this family of mediators is resulting from their specificity - members of the chemokine family induce r …
Natural resolution of inflammation.
Freire MO and Van Dyke TE. Periodontol 2000 2013 - Review. PMID 23931059 Free PMC article.
This review focuses on recent advances in the understanding of the role of endogenous lipid mediators that modulate cellular fate and inflammation. ...Resolution of inflammation is initiated by an active class switch in lipid mediators, such as classic prostaglandins and leukotrienes, to the production of proresolution mediators. ...
This review focuses on recent advances in the understanding of the role of endogenous lipid mediators that modulate cellular fate and …
Computational genomics tools for dissecting tumour-immune cell interactions
Hackl H, et al. Nat Rev Genet 2016 - Review. PMID 27376489
Here, we review computational genomics tools for cancer immunology and provide information on the requirements and functionality in order to assist in the selection of tools and assembly of analytical pipelines....
Here, we review computational genomics tools for cancer immunology and provide information on the requirements and functionality in o …
The cytokine network in acute myeloid leukemia (AML): A focus on pro- and anti-inflammatory mediators.
Binder S, et al. Cytokine Growth Factor Rev 2018 - Review. PMID 30181021
Critical roles of cytokines in the context of inflammation have gained special interest. While pro-inflammatory mediators such as IL-1β, TNF-α and IL-6 tend to increase AML aggressiveness, anti-inflammatory mediators such as TGF-β and IL-10 appear to impede AML progression. ...
Critical roles of cytokines in the context of inflammation have gained special interest. While pro-inflammatory mediators such …
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