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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1802 1
1803 17
1804 5
1805 1
1818 1
1832 1
1835 1
1839 1
1842 1
1843 3
1844 1
1845 2
1848 4
1849 3
1861 2
1870 1
1877 1
1880 4
1881 1
1882 2
1887 1
1889 1
1890 44
1891 23
1892 46
1893 4
1894 14
1895 11
1896 2
1897 4
1898 4
1899 7
1900 7
1901 8
1902 3
1903 1
1905 6
1906 5
1907 7
1908 7
1909 3
1910 4
1911 1
1912 3
1913 4
1915 5
1916 1
1917 1
1918 50
1919 151
1920 35
1921 22
1922 17
1923 16
1924 4
1925 3
1926 6
1927 12
1928 7
1929 12
1930 7
1931 14
1932 9
1933 10
1934 7
1935 13
1936 15
1937 30
1938 12
1939 17
1940 23
1941 22
1942 16
1943 28
1944 36
1945 90
1946 203
1947 199
1948 225
1949 239
1950 253
1951 322
1952 303
1953 349
1954 318
1955 263
1956 236
1957 400
1958 646
1959 514
1960 396
1961 352
1962 345
1963 560
1964 562
1965 389
1966 365
1967 354
1968 456
1969 527
1970 627
1971 602
1972 599
1973 634
1974 605
1975 699
1976 905
1977 965
1978 837
1979 980
1980 964
1981 963
1982 1070
1983 1070
1984 1051
1985 1224
1986 1130
1987 1170
1988 1178
1989 1245
1990 1316
1991 1350
1992 1398
1993 1360
1994 1385
1995 1410
1996 1469
1997 1526
1998 1546
1999 1810
2000 2009
2001 1851
2002 1872
2003 2183
2004 2411
2005 2835
2006 3778
2007 3566
2008 3667
2009 5711
2010 6906
2011 7067
2012 6659
2013 6612
2014 6281
2015 5904
2016 5593
2017 5635
2018 5879
2019 6193
2020 8135
2021 8853
2022 7984
2023 6838
2024 2208

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The role of Epstein-Barr virus in autoimmune and autoinflammatory diseases.
Borghol AH, Bitar ER, Hanna A, Naim G, Rahal EA. Borghol AH, et al. Crit Rev Microbiol. 2024 Apr 18:1-21. doi: 10.1080/1040841X.2024.2344114. Online ahead of print. Crit Rev Microbiol. 2024. PMID: 38634723 Review.
EBV is also known to cause infectious mononucleosis, a self-limited flu-like illness, in adolescents. EBV is often reactivated and it employs several mechanisms of evading the host immune system. ...
EBV is also known to cause infectious mononucleosis, a self-limited flu-like illness, in adolescents. EBV is often reactivated and it …
Changing respiratory pathogens infection patterns after COVID-19 pandemic in Shanghai, China.
Wei M, Li S, Lu X, Hu K, Li Z, Li M. Wei M, et al. J Med Virol. 2024 Apr;96(4):e29616. doi: 10.1002/jmv.29616. J Med Virol. 2024. PMID: 38634514
Children (55.18%, p < 0.05) experienced a significantly higher infection probability than adults (20.88%) and old (20.66%). Influenza A virus (8.63%), Mycoplasma pneumoniae (5.47%), and human rhinovirus (5.12%) were the most common pathogens. ...

Children (55.18%, p < 0.05) experienced a significantly higher infection probability than adults (20.88%) and old (20.66%). Influenza

…
Antiviral activity of adenoviral vector expressing human interferon lambda-4 against influenza virus.
Kim DH, Kim JH, Lim KB, Lee JB, Park SY, Song CS, Lee SW, Lee DH, Choi IS. Kim DH, et al. J Med Virol. 2024 Apr;96(4):e29605. doi: 10.1002/jmv.29605. J Med Virol. 2024. PMID: 38634474
The transduction of rAd-huIFNlambda4 induced ISGs and inhibited four subtypes of the influenza virus in both mouse-derived (LA-4) and human-derived cells (A549). The antiviral state was confirmed in BALB/c mice following intranasal inoculation with 10(9) PFU of rAd-huIFNla …
The transduction of rAd-huIFNlambda4 induced ISGs and inhibited four subtypes of the influenza virus in both mouse-derived (LA-4) and …
Dengue encephalitis: A rare manifestation of dengue fever.
Harshani HBC, Ruwan DVRG, Chathuranga GDD, Weligamagea DCUD, Abeynayake JI. Harshani HBC, et al. J Vector Borne Dis. 2024 Apr 18. doi: 10.4103/JVBD.JVBD_189_23. Online ahead of print. J Vector Borne Dis. 2024. PMID: 38634378
Dengue fever, caused by the dengue virus transmitted by mosquitoes, usually manifests as flu-like symptoms and is a prevalent tropical illness. However, there are rare cases where the infection takes an unusual course, resulting in severe complications like dengue encephal …
Dengue fever, caused by the dengue virus transmitted by mosquitoes, usually manifests as flu-like symptoms and is a prevalent tropica …
Evaluation of Hospitalized Patients with Community-Acquired Influenza-Like Illness During Two Influenza Seasons.
Özgen-Top Ö, Aysert-Yıldız P, Özger HS, Güzel-Tunçcan Ö. Özgen-Top Ö, et al. Infect Dis Clin Microbiol. 2023 Dec 29;5(4):323-331. doi: 10.36519/idcm.2023.285. eCollection 2023 Dec. Infect Dis Clin Microbiol. 2023. PMID: 38633854 Free PMC article.
We aimed to determine the frequency of influenza infections among acute admissions with influenza-like illness (ILI) and evaluate the demographic, clinical findings, and outcomes of patients with influenza. ...The elevation of AST, ALT, and CK in influenza …
We aimed to determine the frequency of influenza infections among acute admissions with influenza-like illness (ILI) and evalu …
Swine influenza A virus: challenges and novel vaccine strategies.
Petro-Turnquist E, Pekarek MJ, Weaver EA. Petro-Turnquist E, et al. Front Cell Infect Microbiol. 2024 Apr 3;14:1336013. doi: 10.3389/fcimb.2024.1336013. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38633745 Free PMC article. Review.
Swine Influenza A Virus (IAV-S) imposes a significant impact on the pork industry and has been deemed a significant threat to global public health due to its zoonotic potential. ...
Swine Influenza A Virus (IAV-S) imposes a significant impact on the pork industry and has been deemed a significant threat to global …
Comparison of 28-Day Mortality Between Hospital- and Community-Acquired Influenza Patients.
Bilgin H, Başarı T, Pazar N, Küçüker I, Can-Sarınoğlu R. Bilgin H, et al. Infect Dis Clin Microbiol. 2023 Sep 30;5(3):231-238. doi: 10.36519/idcm.2023.243. eCollection 2023 Sep. Infect Dis Clin Microbiol. 2023. PMID: 38633557 Free PMC article.
OBJECTIVE: This study aimed to compare 28-day mortality between patients have hospital-acquired influenza (HAI) and those have community-acquired influenza (CAI) during the 2017-2019 influenza seasons in a tertiary care center in Istanbul, Turkiye. MATERIALS …
OBJECTIVE: This study aimed to compare 28-day mortality between patients have hospital-acquired influenza (HAI) and those have commun …
COVID-19: An Update on Epidemiology, Prevention and Treatment, September-2023.
Şimşek-Yavuz S. Şimşek-Yavuz S. Infect Dis Clin Microbiol. 2023 Sep 30;5(3):165-187. doi: 10.36519/idcm.2023.251. eCollection 2023 Sep. Infect Dis Clin Microbiol. 2023. PMID: 38633552 Free PMC article. Review.
COVID-19 is not seen with a predictable frequency, at least two times more deadly than the flu, continues as an epidemic, and has not reached the endemic level yet. ...
COVID-19 is not seen with a predictable frequency, at least two times more deadly than the flu, continues as an epidemic, and has not …
Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus.
Diaz-Cánova D, Moens U, Brinkmann A, Nitsche A, Okeke MI. Diaz-Cánova D, et al. Front Immunol. 2024 Apr 3;15:1277447. doi: 10.3389/fimmu.2024.1277447. eCollection 2024. Front Immunol. 2024. PMID: 38633245 Free PMC article.
We previously conducted co-infection and superinfection experiments with MVA vectored influenza vaccine (MVA-HANP) and a feline Cowpox virus (CPXV-No-F1) in Vero cells (that were semi-permissive to MVA infection) and showed that recombination occurred in both co-infected a …
We previously conducted co-infection and superinfection experiments with MVA vectored influenza vaccine (MVA-HANP) and a feline Cowpo …
Clinical characteristics and assessment of risk factors in patients with influenza A-induced severe pneumonia after the prevalence of SARS-CoV-2.
Ma Y, Gao Q. Ma Y, et al. Open Med (Wars). 2024 Apr 15;19(1):20240953. doi: 10.1515/med-2024-0953. eCollection 2024. Open Med (Wars). 2024. PMID: 38633219 Free PMC article.
METHODS: We retrospectively studied the consecutive case series of 30 patients with confirmed influenza A-induced severe pneumonia treated in the intensive care unit at Dazhou Central Hospital in Sichuan, China, from March 1 to April 30, 2023. ...CONCLUSION: ARDS and septi …
METHODS: We retrospectively studied the consecutive case series of 30 patients with confirmed influenza A-induced severe pneumonia tr …
Expression of recombinant Florida clade 2 hemagglutinin in baculovirus expression system: A step for subunit vaccine development against H3N8 equine influenza virus.
Atwa AS, Gomaa L, Elmenofy W, Amer HM, Ahmed BM. Atwa AS, et al. Open Vet J. 2024 Jan;14(1):350-359. doi: 10.5455/OVJ.2024.v14.i1.32. Epub 2024 Jan 31. Open Vet J. 2024. PMID: 38633177 Free PMC article.
BACKGROUND: Equine influenza (EI) is a transmissible viral respiratory sickness of the Equidae family. ...
BACKGROUND: Equine influenza (EI) is a transmissible viral respiratory sickness of the Equidae family. ...
Impact of SARS-CoV-2 infection on pain crisis and acute chest syndrome in patients with sickle cell anemia: A retrospective multi-cohort study based on US national data from 2020 to 2022.
Alvarado J, Yerigeri K, Boakye A, Randolph C, Roy A, Onimoe G. Alvarado J, et al. EJHaem. 2024 Feb 29;5(2):299-307. doi: 10.1002/jha2.840. eCollection 2024 Apr. EJHaem. 2024. PMID: 38633124 Free PMC article.
A retrospective study was conducted using the TRiNetX health research network database to identify SCA patients ( HbSS, Sbeta-thalassemia zero) who had SARS-CoV-2 infection over 2 years; these were compared with similar patients who did not have the infection in terms of demograp …
A retrospective study was conducted using the TRiNetX health research network database to identify SCA patients ( HbSS, Sbeta-thalassemia ze …
Anti-neuraminidase immunity in the combat against influenza.
Zhang X, Ross TM. Zhang X, et al. Expert Rev Vaccines. 2024 Apr 17. doi: 10.1080/14760584.2024.2343689. Online ahead of print. Expert Rev Vaccines. 2024. PMID: 38632930 Review.
INTRODUCTION: Anti-neuraminidase (NA) immunity correlates with the protection against influenza virus infection in both human and animal models. The aim of this review is to better understand the mechanism of anti-NA immunity, and also to evaluate the approaches on develop …
INTRODUCTION: Anti-neuraminidase (NA) immunity correlates with the protection against influenza virus infection in both human and ani …
Silica Nanowires-Filled Glass Microporous Sensor for the Ultrasensitive Detection of Deoxyribonucleic Acid.
Xu S, Wang G, Feng Y, Zheng J, Huang L, Wang Y, Liu N. Xu S, et al. ACS Sens. 2024 Apr 17. doi: 10.1021/acssensors.4c00072. Online ahead of print. ACS Sens. 2024. PMID: 38632929
Furthermore, based on this excellent selectivity and specificity, we validate the universality of this sensing strategy by detecting DNA (H1N1 and H5N1) sequences associated with the avian influenza virus. By replacing the types of nucleic acid aptamers, it is expected to …
Furthermore, based on this excellent selectivity and specificity, we validate the universality of this sensing strategy by detecting DNA (H1 …
Understanding the views of adult migrants around catch-up vaccination for missed routine immunisations to define strategies to improve coverage: A UK in-depth interview study.
Deal A, Crawshaw AF, Salloum M, Hayward SE, Carter J, Knights F, Seedat F, Bouaddi O, Sanchez-Clemente N, Muzinga Lutumba L, Mimi Kitoko L, Nkembi S, Hickey C, Mounier-Jack S, Majeed A, Hargreaves S. Deal A, et al. Vaccine. 2024 Apr 16:S0264-410X(24)00406-7. doi: 10.1016/j.vaccine.2024.04.005. Online ahead of print. Vaccine. 2024. PMID: 38631950
MMR/Td-IPV) when attending a healthcare facility on arrival in the UK. Vaccines such as flu vaccines, pregnancy-related or pre-travel vaccination were more commonly mentioned. ...
MMR/Td-IPV) when attending a healthcare facility on arrival in the UK. Vaccines such as flu vaccines, pregnancy-related or pre-travel …
Cost-effectiveness of high-dose influenza vaccination in the Netherlands: Incorporating the impact on both respiratory and cardiovascular hospitalizations.
van der Pol S, Zeevat F, Postma MJ, Boersma C. van der Pol S, et al. Vaccine. 2024 Apr 17:S0264-410X(24)00465-1. doi: 10.1016/j.vaccine.2024.04.040. Online ahead of print. Vaccine. 2024. PMID: 38631948
OBJECTIVES: We assess the cost-effectiveness of switching from standard-dose quadrivalent influenza vaccination (SD-QIV) to high-dose vaccination (HD-QIV) for Dutch adults aged 60 years and older. ...CONCLUSIONS: Implementing HD-QIV for adults aged 60 and over within the e …
OBJECTIVES: We assess the cost-effectiveness of switching from standard-dose quadrivalent influenza vaccination (SD-QIV) to high-dose …
Avian 'Bird' Flu - undue media panic or genuine concern for pandemic potential requiring global preparedness action?
Petersen E, Memish ZA, Hui DS, Scagliarini A, Simonsen L, Simulundu E, Bloodgood J, Blumberg L, Shan Lee S, Zumla A. Petersen E, et al. Int J Infect Dis. 2024 Apr 15:107062. doi: 10.1016/j.ijid.2024.107062. Online ahead of print. Int J Infect Dis. 2024. PMID: 38631509
epidemics, avian influenza, H5N1, highly pathogenic avian influenza, HPAI....
epidemics, avian influenza, H5N1, highly pathogenic avian influenza, HPAI....
Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub.
Jung SM, Loo SL, Howerton E, Contamin L, Smith CP, Carcelén EC, Yan K, Bents SJ, Levander J, Espino J, Lemaitre JC, Sato K, McKee CD, Hill AL, Chinazzi M, Davis JT, Mu K, Vespignani A, Rosenstrom ET, Rodriguez-Cartes SA, Ivy JS, Mayorga ME, Swann JL, España G, Cavany S, Moore SM, Perkins TA, Chen S, Paul R, Janies D, Thill JC, Srivastava A, Aawar MA, Bi K, Bandekar SR, Bouchnita A, Fox SJ, Meyers LA, Porebski P, Venkatramanan S, Adiga A, Hurt B, Klahn B, Outten J, Chen J, Mortveit H, Wilson A, Hoops S, Bhattacharya P, Machi D, Vullikanti A, Lewis B, Marathe M, Hochheiser H, Runge MC, Shea K, Truelove S, Viboud C, Lessler J. Jung SM, et al. PLoS Med. 2024 Apr 17;21(4):e1004387. doi: 10.1371/journal.pmed.1004387. Online ahead of print. PLoS Med. 2024. PMID: 38630802 Free article.
In the most pessimistic scenario (high immune escape, no vaccination recommendation), we project 2.1 million (90% projection interval (PI) [1,438,000, 4,270,000]) hospitalizations and 209,000 (90% PI [139,000, 461,000]) deaths, exceeding pre-pandemic mortality of influenza …
In the most pessimistic scenario (high immune escape, no vaccination recommendation), we project 2.1 million (90% projection interval (PI) [ …
Vaccine-Preventable Disease Outbreaks among Healthcare Workers: A Scoping Review.
Hasan T, Lynch M, King C, Wehbe C, Plymoth M, Islam MS, Iannuzzi T, Dao A, Lai J, Martiniuk A, Desai S, Sheel M. Hasan T, et al. Clin Infect Dis. 2024 Apr 17:ciae209. doi: 10.1093/cid/ciae209. Online ahead of print. Clin Infect Dis. 2024. PMID: 38630638
RESULTS: Our search found 9363 articles, of which 216 met inclusion criteria. Studies describing six of the ten VPDs were found: influenza, measles, varicella, tuberculosis, pertussis and rubella. Most articles (93%) were from high- and upper middle-income countries. While …
RESULTS: Our search found 9363 articles, of which 216 met inclusion criteria. Studies describing six of the ten VPDs were found: influenz …
Comparing PCSK9 Monoclonal Antibody Treatment Strategies Following Myocardial Infarction Using Negative Control Outcomes: A Target Trial Emulation Study.
Sloot R, Breskin A, Colantonio LD, Allmon AG, Yu Y, Sakhuja S, Chen L, Muntner P, Brookhart MA, Dhalwani N. Sloot R, et al. Epidemiology. 2024 Mar 12. doi: 10.1097/EDE.0000000000001730. Online ahead of print. Epidemiology. 2024. PMID: 38629975
In CDM, there was a lower risk for cancer (RD = -3.6% [95% CI: -4.3%, -2.9%]), decubitus ulcer (RD = -7.7% [95% CI: -11.8%, -3.7%]), fracture (RD = -8.1% [95% CI: -9.6%, -6.6%]), influenza vaccine (RD = -9.3% [95% CI: -17.5%, -1.1%]), and visual test (RD = -0.6% [95% CI: - …
In CDM, there was a lower risk for cancer (RD = -3.6% [95% CI: -4.3%, -2.9%]), decubitus ulcer (RD = -7.7% [95% CI: -11.8%, -3.7%]), fractur …
Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells.
Bougon J, Kadijk E, Gallot-Lavallee L, Curtis BA, Landers M, Archibald JM, Khaperskyy DA. Bougon J, et al. J Virol. 2024 Apr 17:e0190123. doi: 10.1128/jvi.01901-23. Online ahead of print. J Virol. 2024. PMID: 38629840
Influenza A virus encodes two proteins that function in host shutoff: the nonstructural protein 1 (NS1) and the polymerase acidic X (PA-X). ...In this work, we examined whether NS1 and PA-X functionally interact and discovered that NS1 is required for PA-X to function effe …
Influenza A virus encodes two proteins that function in host shutoff: the nonstructural protein 1 (NS1) and the polymerase acidic X ( …
["God for us!": Catholic festivals and rites in times of epidemics, Salvador-BA, Brasil, 1918-1919].
Couto ES. Couto ES. Hist Cienc Saude Manguinhos. 2024 Apr 15;31:e2024009. doi: 10.1590/S0104-59702024000100009. eCollection 2024. Hist Cienc Saude Manguinhos. 2024. PMID: 38629658 Free PMC article. Portuguese.
This article analyzes the reactions of Catholics linked to lay associations in the city of Salvador, in the period of the Spanish flu (1918) and smallpox (1919). Newspapers were the main sources used to identify the festivals and rites, both those practiced to ask for the …
This article analyzes the reactions of Catholics linked to lay associations in the city of Salvador, in the period of the Spanish flu …
Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination.
Hou Y, Deng G, Cui P, Zeng X, Li B, Wang D, He X, Yan C, Zhang Y, Li J, Ma J, Li Y, Wang X, Tian G, Kong H, Tang L, Suzuki Y, Shi J, Chen H. Hou Y, et al. Emerg Microbes Infect. 2024 Apr 17:2343912. doi: 10.1080/22221751.2024.2343912. Online ahead of print. Emerg Microbes Infect. 2024. PMID: 38629574 Free article.
Human infections with the H7N9 influenza virus have been eliminated in China through vaccination of poultry; however, the H7N9 virus has not yet been eradicated from poultry. Carefully analysis of H7N9 viruses in poultry that have sub-optimal immunity may provide a unique …
Human infections with the H7N9 influenza virus have been eliminated in China through vaccination of poultry; however, the H7N9 virus …
[Source Apportionment of Morphine in Wastewater].
Shao XT, Zhao YT, Jiang B, Pei W, Li YY, Tan DQ, Wang DG. Shao XT, et al. Huan Jing Ke Xue. 2024 May 8;45(5):2748-2756. doi: 10.13227/j.hjkx.202306005. Huan Jing Ke Xue. 2024. PMID: 38629538 Chinese.
The different sources varied in these months due to the COVID-19 and influenza A outbreaks, in which the use of drugs containing poppy straws and codeine was the main source, whereas the use of morphine analgesics remained relatively stable. ...
The different sources varied in these months due to the COVID-19 and influenza A outbreaks, in which the use of drugs containing popp …
Influenza vaccination coverage and determinants of vaccination in peripheral arterial disease patients.
Chastaingt L, Toba ML, Boulon C, Dari L, Constans J, Daoud H, Chauvet R, Adou C, Magne J, Lacroix P. Chastaingt L, et al. Vasa. 2024 Apr 17. doi: 10.1024/0301-1526/a001120. Online ahead of print. Vasa. 2024. PMID: 38629325
Background: In the latest American Heart Association guidelines, influenza vaccination is recommended for patients with peripheral arterial disease (PAD). ...Conclusions: This study highlights the low adherence to influenza vaccination in the PAD population of 2 uni …
Background: In the latest American Heart Association guidelines, influenza vaccination is recommended for patients with peripheral ar …
Musculoskeletal Coccidioidomycosis in the Setting of Adalimumab: A Case Report.
Nehzati A, Hefelfinger D, Fonte E, Scott J. Nehzati A, et al. Cureus. 2024 Mar 17;16(3):e56321. doi: 10.7759/cureus.56321. eCollection 2024 Mar. Cureus. 2024. PMID: 38629004 Free PMC article.
Symptomatic primary infection of coccidioidomycosis can present as pneumonia with influenza-like symptoms, but the majority of cases remain asymptomatic. ...
Symptomatic primary infection of coccidioidomycosis can present as pneumonia with influenza-like symptoms, but the majority of cases …
Impact of influenza related hospitalization in Spain: characteristics and risk factor of mortality during five influenza seasons (2016 to 2021).
Ramos-Rincón JM, Pinargote-Celorio H, González-de-la-Aleja P, Sánchez-Payá J, Reus S, Rodríguez-Díaz JC, Merino E. Ramos-Rincón JM, et al. Front Public Health. 2024 Apr 2;12:1360372. doi: 10.3389/fpubh.2024.1360372. eCollection 2024. Front Public Health. 2024. PMID: 38628848 Free PMC article.
This study aims to (a) describe the clinical characteristics of hospitalizations with a diagnosis of influenza over five flu seasons (2016-2017 to 2020-2021), (b) assess the associated morbidity (hospitalization rates and ICU admissions rate), mortality and cost of …
This study aims to (a) describe the clinical characteristics of hospitalizations with a diagnosis of influenza over five flu s …
Etiology of bacterial pneumonia and multi-drug resistance pattern among pneumonia suspected patients in Ethiopia: a systematic review and meta-analysis.
Tilahun M, Belete MA, Gedefie A, Debash H, Alemayehu E, Gebretsadik D, Ebrahim H, Mohammed O. Tilahun M, et al. BMC Pulm Med. 2024 Apr 16;24(1):182. doi: 10.1186/s12890-024-03000-1. BMC Pulm Med. 2024. PMID: 38627640 Free PMC article.
Streptococcus pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa are the most common causative agents of pneumonia, and they have developed high MDR in recent decades in Ethiopia. ...
Streptococcus pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa are the most common causative age …
Automated quantification of avian influenza virus antigen in different organs.
Landmann M, Scheibner D, Gischke M, Abdelwhab EM, Ulrich R. Landmann M, et al. Sci Rep. 2024 Apr 16;14(1):8766. doi: 10.1038/s41598-024-59239-5. Sci Rep. 2024. PMID: 38627481 Free PMC article.
As immunohistochemistry is valuable for determining tissue and cell tropism of avian influenza viruses (AIV), but time-consuming, an artificial intelligence-based workflow was developed to automate the AIV antigen quantification. Organ samples from experimental AIV infecti …
As immunohistochemistry is valuable for determining tissue and cell tropism of avian influenza viruses (AIV), but time-consuming, an …
The immunodominance of antigenic site Sb on the H1 influenza virus hemagglutinin increases with high immunoglobulin titers of the cohorts and with young age, but not sex.
Martínez JL, Lemus N, Lai TY, Mishra M, González-Domínguez I, Puente-Massaguer E, Loganathan M, Francis B, Samanovic MI, Krammer F, Mulligan MJ, Simon V, Palese P, Sun W. Martínez JL, et al. Vaccine. 2024 Apr 15:S0264-410X(24)00451-1. doi: 10.1016/j.vaccine.2024.04.037. Online ahead of print. Vaccine. 2024. PMID: 38627145
The head domain of the hemagglutinin of influenza viruses plays a dominant role in the antibody response due to the presence of immunodominant antigenic sites that are the main targets of host neutralizing antibodies. ...To determine the antibody prevalence towards each ma …
The head domain of the hemagglutinin of influenza viruses plays a dominant role in the antibody response due to the presence of immun …
Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015-2020).
Lee J, Seo H, Kim D, Hwang J, Kwon JW. Lee J, et al. J Microbiol Immunol Infect. 2024 Apr 5:S1684-1182(24)00071-9. doi: 10.1016/j.jmii.2024.04.003. Online ahead of print. J Microbiol Immunol Infect. 2024. PMID: 38627123
BACKGROUND: Influenza's potential impact on active tuberculosis (TB) development has been debated, with limited clinical evidence. ...Cox proportional-hazards regression analysis indicated that influenza was not a risk factor for incident TB in the TPT group. Howeve …
BACKGROUND: Influenza's potential impact on active tuberculosis (TB) development has been debated, with limited clinical evidence. .. …
Evidence for vagal sensory neural involvement in influenza pathogenesis and disease.
Verzele NAJ, Chua BY, Short KR, Moe AAK, Edwards IN, Bielefeldt-Ohmann H, Hulme KD, Noye EC, Tong MZW, Reading PC, Trewella MW, Mazzone SB, McGovern AE. Verzele NAJ, et al. PLoS Pathog. 2024 Apr 16;20(4):e1011635. doi: 10.1371/journal.ppat.1011635. Online ahead of print. PLoS Pathog. 2024. PMID: 38626267 Free article.
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. ...
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. ...
Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections.
VanInsberghe D, McBride DS, DaSilva J, Stark TJ, Lau MSY, Shepard SS, Barnes JR, Bowman AS, Lowen AC, Koelle K. VanInsberghe D, et al. PLoS Pathog. 2024 Apr 16;20(4):e1012131. doi: 10.1371/journal.ppat.1012131. Online ahead of print. PLoS Pathog. 2024. PMID: 38626244 Free article.
Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly characterized in non-human hosts. ...
Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these pa …
COVID-19 Vaccine Hesitancy Among People Living with HIV: A Systematic Review and Meta-Analysis.
Liu X, Wu Y, Huo Z, Zhang L, Jing S, Dai Z, Huang Y, Si M, Xin Y, Qu Y, Tang S, Su X. Liu X, et al. AIDS Behav. 2024 Apr 16. doi: 10.1007/s10461-024-04344-9. Online ahead of print. AIDS Behav. 2024. PMID: 38625625 Review.
The prevalence of COVID-19 vaccine hesitancy among PLWH was 34.0%, and the influencing factors included male, influenza vaccination experience, and a CD4 count of more than 200 cells/mm(3). ...
The prevalence of COVID-19 vaccine hesitancy among PLWH was 34.0%, and the influencing factors included male, influenza vaccination e …
Molecular characterization of the whole genome of H9N2 avian influenza virus isolated from Egyptian poultry farms.
Bedair NM, Sakr MA, Mourad A, Eissa N, Mostafa A, Khamiss O. Bedair NM, et al. Arch Virol. 2024 Apr 16;169(5):99. doi: 10.1007/s00705-024-06018-2. Arch Virol. 2024. PMID: 38625394 Free PMC article.
H9N2 avian influenza viruses (AIVs) affect both poultry and humans on a global level, and they are especially prevalent in Egypt. ...
H9N2 avian influenza viruses (AIVs) affect both poultry and humans on a global level, and they are especially prevalent in Egypt. ...
Synthesis of Rupestonic Acid L-Ephedrine Derivatives with Preliminary In vitro Anti-influenza Viral Activity.
Yong J, Lu C. Yong J, et al. Curr Pharm Des. 2024 Apr 15. doi: 10.2174/0113816128282194240329045625. Online ahead of print. Curr Pharm Des. 2024. PMID: 38623973
BACKGROUND: Influenza virus is a kind of RNA virus. Nowadays, the high incidence of influenza and the morbidity and mortality of epidemic influenza are substantial. It has been reported that one hundred million people in the world are infected with influen …
BACKGROUND: Influenza virus is a kind of RNA virus. Nowadays, the high incidence of influenza and the morbidity and mortality …
Generation of Broad Protection against Influenza with Di-Tyrosine-Cross-Linked M2e Nanoclusters.
Wilks LR, Joshi G, Rychener N, Gill HS. Wilks LR, et al. ACS Infect Dis. 2024 Apr 16. doi: 10.1021/acsinfecdis.3c00429. Online ahead of print. ACS Infect Dis. 2024. PMID: 38623820
In this study, NCs were generated using the ectodomain of the ion channel Matrix 2 (M2e) protein, a conserved influenza surface antigen. The NCs were administered via intranasal (IN) or intramuscular (IM) routes in a mouse model in a prime-boost regimen in the presence of …
In this study, NCs were generated using the ectodomain of the ion channel Matrix 2 (M2e) protein, a conserved influenza surface antig …
Evaluating Pilot Implementation of 'PenCS Flu Topbar' App in Medical Practices to Improve National Immunisation Program-Funded Seasonal Influenza Vaccination in Central Queensland, Australia.
Khandaker G, Chapman G, Khan A, Al Imam MH, Menzies R, Smoll N, Walker J, Kirk M, Wiley K. Khandaker G, et al. Influenza Other Respir Viruses. 2024 Apr;18(4):e13280. doi: 10.1111/irv.13280. Influenza Other Respir Viruses. 2024. PMID: 38623599 Free PMC article.
METHODS: We evaluated the app's user experience and examined whether the introduction of 'PenCS Flu Topbar' in medical practices could improve the coverage of NIP-funded influenza vaccinations. We conducted a mixed-method study including a qualitative analysis of in …
METHODS: We evaluated the app's user experience and examined whether the introduction of 'PenCS Flu Topbar' in medical practices coul …
Vaccination coverage during pregnancy and factors associated with refusal of recommended vaccinations: An Italian cross sectional study.
Seravalli V, Romualdi I, Ammar O, De Blasi C, Boccalini S, Bechini A, Di Tommaso M. Seravalli V, et al. Vaccine X. 2024 Apr 8;18:100483. doi: 10.1016/j.jvacx.2024.100483. eCollection 2024 Jun. Vaccine X. 2024. PMID: 38623567 Free PMC article.
BACKGROUND: The vaccines recommended during pregnancy are the Tdap, the influenza vaccine, and, during the SARS-CoV-2 pandemic, the vaccine against COVID-19. ...CONCLUSIONS: Adherence to the influenza vaccine was low because of reduced perception of the disease risk …
BACKGROUND: The vaccines recommended during pregnancy are the Tdap, the influenza vaccine, and, during the SARS-CoV-2 pandemic, the v …
Short-Term Nitrogen Dioxide Exposure and Emergency Hospital Admissions for Asthma in Children: A Case-Crossover Analysis in England.
Wang W, Gulliver J, Beevers S, Freni Sterrantino A, Davies B, Atkinson RW, Fecht D. Wang W, et al. J Asthma Allergy. 2024 Apr 9;17:349-359. doi: 10.2147/JAA.S448600. eCollection 2024. J Asthma Allergy. 2024. PMID: 38623450 Free PMC article.
Conditional logistic regression models were used to obtain the odds ratios (OR) and confidence intervals (CI) after adjusting for temperature, relative humidity, bank holidays, and influenza rates. The effect modifications by age, sex, season, area-level income deprivation …
Conditional logistic regression models were used to obtain the odds ratios (OR) and confidence intervals (CI) after adjusting for temperatur …
The Evaluation of the BioFire FilmArray Meningitis/Encephalitis Panel for the Detection of Bacteria and Yeast in Cerebrospinal Fluid Specimens.
Ben Lahlou Y, Eddair Y, Dokponou YCH, Elouennass M, Chadli M. Ben Lahlou Y, et al. Cureus. 2024 Mar 16;16(3):e56260. doi: 10.7759/cureus.56260. eCollection 2024 Mar. Cureus. 2024. PMID: 38623118 Free PMC article.
Results The overall agreement rate with FilmArray in our study was 86%. The sensitivity to Escherichia coli K1, Haemophilus influenzae, Neisseria meningitidis, Streptococcus agalactiae, and Streptococcus pneumoniae was 100%. ...
Results The overall agreement rate with FilmArray in our study was 86%. The sensitivity to Escherichia coli K1, Haemophilus influenzae …
Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea.
Sim JK, Lee HS, Yang J, Gwack J, Kim BI, Cha JO, Min KH, Lee YS; Severe Acute Respiratory Infection (SARI) Investigators. Sim JK, et al. J Korean Med Sci. 2024 Apr 15;39(14):e128. doi: 10.3346/jkms.2024.39.e128. J Korean Med Sci. 2024. PMID: 38622937 Free PMC article.
We extracted data for influenza patients who were infected between 2018 and 2019 and COVID-19 patients who were infected in 2021 (pre-omicron period) and 2022 (omicron period). ...Clinical presentations exhibited similarities between the pre-omicron and omicron cohorts; ho …
We extracted data for influenza patients who were infected between 2018 and 2019 and COVID-19 patients who were infected in 2021 (pre …
A case of Crimean-Congo haemorrhagic fever complicated with portal vein thrombosis and hemophagocytosis.
Çaydaşı Ö, Arslan E, Adıyeke E, Kuzan TY, Karadağ FY, Engin DÖ. Çaydaşı Ö, et al. Trop Med Int Health. 2024 Apr 15. doi: 10.1111/tmi.13995. Online ahead of print. Trop Med Int Health. 2024. PMID: 38622770
CONCLUSION: The clinical presentation of CCHF can range from self-limiting flu-like to severe symptoms possibly fatal. Acute portal vein embolism is a rare complication that has not been reported before to our knowledge. ...
CONCLUSION: The clinical presentation of CCHF can range from self-limiting flu-like to severe symptoms possibly fatal. Acute portal v …
Exploring the immune-inflammatory mechanism of Maxing Shigan Decoction in treating influenza virus A-induced pneumonia based on an integrated strategy of single-cell transcriptomics and systems biology.
Zhang S, Li B, Zeng L, Yang K, Jiang J, Lu F, Li L, Li W. Zhang S, et al. Eur J Med Res. 2024 Apr 15;29(1):234. doi: 10.1186/s40001-024-01777-9. Eur J Med Res. 2024. PMID: 38622728 Free PMC article.
BACKGROUND: Influenza is an acute respiratory infection caused by influenza virus. Maxing Shigan Decoction (MXSGD) is a commonly used traditional Chinese medicine prescription for the prevention and treatment of influenza. However, its mechanism remains uncle …
BACKGROUND: Influenza is an acute respiratory infection caused by influenza virus. Maxing Shigan Decoction (MXSGD) is a common …
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease.
Gao J, Yang Y, Xiang X, Zheng H, Yi X, Wang F, Liang Z, Chen D, Shi W, Wang L, Wu D, Feng S, Huang Q, Li X, Shu W, Chen R, Zhong N, Wang Z. Gao J, et al. Respir Res. 2024 Apr 16;25(1):165. doi: 10.1186/s12931-024-02805-2. Respir Res. 2024. PMID: 38622589 Free article.
Integration of concurrent host transcriptomic data identified correlations between the expression of host genes and their genetically-linked microbiome features, including NUDT1, MAD1L1 and Veillonella parvula, TTLL9 and Stenotrophomonas maltophilia, and LTA4H and Haemophilus …
Integration of concurrent host transcriptomic data identified correlations between the expression of host genes and their genetically-linked …
Does shortage of GPs matter? A cross-sectional study of practice population life expectancy.
Baker R, Levene LS, Newby C, Freeman GK. Baker R, et al. Br J Gen Pract. 2024 Apr 15:BJGP.2023.0195. doi: 10.3399/BJGP.2023.0195. Online ahead of print. Br J Gen Pract. 2024. PMID: 38621806
Sixteen non-correlated variables were entered into multivariable weighted regression models: population characteristics (Index of Multiple Deprivation, region, % White ethnicity, and % on diabetes register); practice organisation (total NHS payments to practices expressed as paym …
Sixteen non-correlated variables were entered into multivariable weighted regression models: population characteristics (Index of Multiple D …
Interaction and Antiviral Treatment of Coinfection between SARS-CoV-2 and Influenza in Vitro.
Liu D, Leung KY, Lam HY, Zhang R, Fan Y, Xie X, Chan KH, Hung IF. Liu D, et al. Virus Res. 2024 Apr 13:199371. doi: 10.1016/j.virusres.2024.199371. Online ahead of print. Virus Res. 2024. PMID: 38621598
On the contrary, the replication of the influenza virus was not affected by the SARS-CoV-2. Molnupiravir monotherapy had significant inhibitory effect on SARS-CoV-2 when the concentration reached to 6.25muM but did not show any significant anti-influenza activity. B …
On the contrary, the replication of the influenza virus was not affected by the SARS-CoV-2. Molnupiravir monotherapy had significant …
Automatic ultrasensitive lateral flow immunoassay based on a color-enhanced signal amplification strategy.
Jie H, Wang Y, Zhao M, Wang X, Wang Z, Zeng L, Cao X, Xu T, Xia F, Liu Q. Jie H, et al. Biosens Bioelectron. 2024 Mar 30;256:116262. doi: 10.1016/j.bios.2024.116262. Online ahead of print. Biosens Bioelectron. 2024. PMID: 38621340
Additionally, in the inactivated virus detections, LOD equivalent to chemiluminescence (0.018 TCID(50)/mL) was obtained, and it had excellent specificity under the interference of other respiratory viruses. High sensitivity has also been achieved for detection of influenza …
Additionally, in the inactivated virus detections, LOD equivalent to chemiluminescence (0.018 TCID(50)/mL) was obtained, and it had excellen …
Traditional Chinese medicine for the COVID-19 pandemic: An online cross-sectional survey among health care workers.
Jin X, Xu L, Lu C, Xue X, Liu X, Zhou Y, Hu X, Liu J, Pei X. Jin X, et al. Eur J Integr Med. 2023 Jun 27:102273. doi: 10.1016/j.eujim.2023.102273. Online ahead of print. Eur J Integr Med. 2023. PMID: 38620124 Free PMC article.
Xiamen preventative formula (a government-approved fixed prescription) (45.22%) and Lianhua Qingwen preparations (18.95%) were the most commonly used Chinese medicines. Thirty-six participants reported flu-like symptoms and three were diagnosed with COVID-19. Flu-li …
Xiamen preventative formula (a government-approved fixed prescription) (45.22%) and Lianhua Qingwen preparations (18.95%) were the most comm …
Acute Cardiac Events in Hospitalized Older Adults With Respiratory Syncytial Virus Infection.
Woodruff RC, Melgar M, Pham H, Sperling LS, Loustalot F, Kirley PD, Austin E, Yousey-Hindes K, Openo KP, Ryan P, Brown C, Lynfield R, Davis SS, Barney G, Tesini B, Sutton M, Talbot HK, Zahid H, Kim L, Havers FP; Respiratory Syncytial Virus Hospitalization Surveillance Network (RSV-NET). Woodruff RC, et al. JAMA Intern Med. 2024 Apr 15:e240212. doi: 10.1001/jamainternmed.2024.0212. Online ahead of print. JAMA Intern Med. 2024. PMID: 38619857
Less is known about the cardiac complications of RSV disease compared with those of influenza and SARS-CoV-2 infection. OBJECTIVE: To describe the prevalence and severity of acute cardiac events during hospitalizations among adults aged 50 years or older with RSV infection …
Less is known about the cardiac complications of RSV disease compared with those of influenza and SARS-CoV-2 infection. OBJECTIVE: To …
Influenza vaccine uptake in juvenile idiopathic arthritis: a multi-centre cross-sectional study.
Maritsi D, Dasoula F, Ziv A, Bizjak M, Balažiová B, Matošević M, Yildiz M, Alpert N, Lamot L, Kasapcopur O, Dallos T, Uziel Y, Toplak N, Heshin-Bekenstein M. Maritsi D, et al. Eur J Pediatr. 2024 Apr 15. doi: 10.1007/s00431-024-05552-0. Online ahead of print. Eur J Pediatr. 2024. PMID: 38619568
While most countries provide safe and effective influenza vaccines for at-risk groups, influenza vaccine coverage among children with rheumatic diseases remains uncertain. ...A multi-centre, cross-sectional anonymous survey was conducted in 7 countries during the 20 …
While most countries provide safe and effective influenza vaccines for at-risk groups, influenza vaccine coverage among childr …
Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses.
Stolley JM, Scott MC, O'Flanagan SD, Künzli M, Matson CA, Weyu E, Langlois RA, Vezys V, Masopust D. Stolley JM, et al. J Immunol. 2024 Apr 15:ji2400010. doi: 10.4049/jimmunol.2400010. Online ahead of print. J Immunol. 2024. PMID: 38619284
Furthermore, infection-experienced medLNs supported better naive T cell surveillance and effector responses to new unrelated infections that exhibited more biased accumulation and memory establishment within the lung. Moreover, we observed that weight loss induced by influenza …
Furthermore, infection-experienced medLNs supported better naive T cell surveillance and effector responses to new unrelated infections that …
In Patients With Inflammatory Bowel Disease, Racial Disparities Exist in Burden of Vaccine-preventable Disease Hospitalizations and Outcomes.
Karime C, Salazar M, Black CN, Caldera F, Okafor PN, Hammami MB, Hashash JG, Farraye FA. Karime C, et al. J Clin Gastroenterol. 2024 Apr 16. doi: 10.1097/MCG.0000000000002005. Online ahead of print. J Clin Gastroenterol. 2024. PMID: 38619208
Non-white patients were at greater odds of hospitalization from influenza (aOR: 1.74), herpes zoster virus (aOR: 1.77), and varicella zoster virus (aOR: 1.62). ...
Non-white patients were at greater odds of hospitalization from influenza (aOR: 1.74), herpes zoster virus (aOR: 1.77), and varicella …
Seasonal influenza vaccine performance and the potential benefits of mRNA vaccines.
Russell CA, Fouchier RAM, Ghaswalla P, Park Y, Vicic N, Ananworanich J, Nachbagauer R, Rudin D. Russell CA, et al. Hum Vaccin Immunother. 2024 Dec 31;20(1):2336357. doi: 10.1080/21645515.2024.2336357. Epub 2024 Apr 15. Hum Vaccin Immunother. 2024. PMID: 38619079 Free PMC article. Review.
Influenza remains a public health threat, partly due to suboptimal effectiveness of vaccines. ...In this review, we summarize the evidence for antigenic drift of circulating viruses and/or egg-adaptive mutations occurring in vaccine strains during the 2011-2020 influenz …
Influenza remains a public health threat, partly due to suboptimal effectiveness of vaccines. ...In this review, we summarize the evi …
Acceptance and willingness to pay for DTaP-HBV-IPV-Hib hexavalent vaccine among parents: A cross-sectional survey in China.
Huang A, Xu X, Tang L, Huang L, Li J, Zhang X, Liu J, Zhou Y, Zhang B, Wang L, Zhang Q, Zhou Z, Wang Y, Wang X, Liu Q, Liu S, Yin Z, Wang F. Huang A, et al. Hum Vaccin Immunother. 2024 Dec 31;20(1):2333098. doi: 10.1080/21645515.2024.2333098. Epub 2024 Apr 15. Hum Vaccin Immunother. 2024. PMID: 38619056 Free PMC article.
DTaP-HBV-IPV-Hib hexavalent vaccine has been used in high-income countries for many years to prevent diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and invasive Haemophilus influenzae type b disease. Currently, no hexavalent vaccines have been approved for use …
DTaP-HBV-IPV-Hib hexavalent vaccine has been used in high-income countries for many years to prevent diphtheria, tetanus, pertussis, hepatit …
Miller-Fisher Syndrome Following Influenza A Infection.
Mitsuhashi S, Suzuki A, Hayashi K, Sato M, Nakaya Y, Takaku N, Kobayashi Y. Mitsuhashi S, et al. Cureus. 2024 Mar 12;16(3):e56064. doi: 10.7759/cureus.56064. eCollection 2024 Mar. Cureus. 2024. PMID: 38618457 Free PMC article.
This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1a antibodies following Influenza A infection. The patient, a 47-year-old woman, contracted Influenza A three weeks before admission. ...
This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1a antibodies following Influenza A infec …
Post-infectious Transverse Myelitis Secondary to Hand, Foot, and Mouth Disease in a Pregnant Daycare Worker.
Jahangiri M, Padarti A, Kilgo WA. Jahangiri M, et al. Cureus. 2024 Mar 14;16(3):e56159. doi: 10.7759/cureus.56159. eCollection 2024 Mar. Cureus. 2024. PMID: 38618390 Free PMC article.
About half of the cases are caused by an infection, usually a viral respiratory infection, flu-like illness, or sometimes a gastrointestinal infection. Although coxsackieviruses and enteroviruses are known to cause TM, it is more commonly associated with respiratory sympto …
About half of the cases are caused by an infection, usually a viral respiratory infection, flu-like illness, or sometimes a gastroint …
SARS-CoV-2 with Influenza B Coinfection in a Patient with Sickle Cell HbSC Presenting with Painful Crisis: A Case Report.
Ali EA, Fadul A, Subahi EA, Ahmed M, Elamin A, Thwin M, Guillaume E. Ali EA, et al. Cureus. 2024 Mar 13;16(3):e56102. doi: 10.7759/cureus.56102. eCollection 2024 Mar. Cureus. 2024. PMID: 38618320 Free PMC article.
Patients with sickle cell HbSC are reported to have a milder form of the disease than HbSS. Coinfection with SARS-CoV-2 and influenza B is rarely reported in patients with hematologic diseases, including sickle cell hemoglobinopathy. We are reporting an unusual case of a p …
Patients with sickle cell HbSC are reported to have a milder form of the disease than HbSS. Coinfection with SARS-CoV-2 and influenza …
Effectiveness of the Sanofi/GSK (VidPrevtyn Beta) and Pfizer-BioNTech (Comirnaty Original/Omicron BA.4-5) bivalent vaccines against hospitalisation in England.
Kirsebom FCM, Andrews N, Stowe J, Dabrera G, Ramsay M, Lopez Bernal J. Kirsebom FCM, et al. EClinicalMedicine. 2024 Apr 10;71:102587. doi: 10.1016/j.eclinm.2024.102587. eCollection 2024 May. EClinicalMedicine. 2024. PMID: 38618208 Free PMC article.
Analyses were adjusted for week of test, gender, age, clinical risk group status, care home resident status, region, index of multiple deprivation, ethnicity, influenza vaccination status and recent COVID-19 positivity. FINDINGS: There were 14,169 eligible tests from hospi …
Analyses were adjusted for week of test, gender, age, clinical risk group status, care home resident status, region, index of multiple depri …
Pyrogallol protects against influenza A virus-triggered lethal lung injury by activating the Nrf2-PPAR-gamma-HO-1 signaling axis.
Zhou B, Wang L, Yang S, Liang Y, Zhang Y, Liu X, Pan X, Li J. Zhou B, et al. MedComm (2020). 2024 Apr 12;5(4):e531. doi: 10.1002/mco2.531. eCollection 2024 Apr. MedComm (2020). 2024. PMID: 38617435 Free PMC article.
Nevertheless, the mechanisms underlying the protective properties of pyrogallol against influenza A virus infection are not yet established. We established in this study that pyrogallol effectively alleviated H1N1 influenza A virus-induced lung injury and reduced mo …
Nevertheless, the mechanisms underlying the protective properties of pyrogallol against influenza A virus infection are not yet estab …
Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City.
Meade PS, Bandawane P, Bushfield K, Hoxie I, Azcona KR, Burgos D, Choudhury S, Diaby A, Diallo M, Gaynor K, Huang A, Kante K, Khan SN, Kim W, Ajayi PK, Roubidoux E, Nelson S, McMahon R, Albrecht RA, Krammer F, Marizzi C. Meade PS, et al. bioRxiv [Preprint]. 2024 Apr 4:2024.04.04.588061. doi: 10.1101/2024.04.04.588061. bioRxiv. 2024. PMID: 38617218 Free PMC article. Preprint.
Highly pathogenic avian influenza viruses of the H5N1 clade 2.3.4.4b arrived in North America in the winter of 2021/2022. ...Our work highlights that the interface between animals and humans that may give rise to zoonotic infections or even pandemics is not limited to rura …
Highly pathogenic avian influenza viruses of the H5N1 clade 2.3.4.4b arrived in North America in the winter of 2021/2022. ...Our work …
Respiratory pathogenic microbial infections: a narrative review.
Long Y, Zheng Y, Li C, Guo Z, Li P, Zhang F, Liu W, Wang Y. Long Y, et al. Int J Med Sci. 2024 Mar 17;21(5):826-836. doi: 10.7150/ijms.93628. eCollection 2024. Int J Med Sci. 2024. PMID: 38617014 Free PMC article. Review.
In the post COVID-19 era, there has been a surge in the prevalence of influenza virus A and other multiple known viruses causing cold compared with during the same period in the previous three years, which coincided with countries easing COVID-19 restrictions worldwide. .. …
In the post COVID-19 era, there has been a surge in the prevalence of influenza virus A and other multiple known viruses causing cold …
[Vaccination updates for the elderly].
Malézieux-Picard A, Buvelot H, Royston L, Eberhardt CS, Prendki V. Malézieux-Picard A, et al. Rev Med Suisse. 2024 Apr 10;20(869):744-747. doi: 10.53738/REVMED.2024.20.869.744. Rev Med Suisse. 2024. PMID: 38616685 French.
Vaccines are some of the most effective preventive measures for limiting morbidity and mortality related to some of those infections, such as influenza or shingles. In order to improve vaccination coverage, it is essential to inform the patients of the benefits of vaccinat …
Vaccines are some of the most effective preventive measures for limiting morbidity and mortality related to some of those infections, such a …
Predictors of Respiratory Syncytial Virus, Influenza Virus, and Human Metapneumovirus Carriage in Children Under 5 Years With WHO-Defined Fast-Breathing Pneumonia in Pakistan.
Nisar MI, Kerai S, Shahid S, Qazi MF, Rehman S, Aziz F, Jehan F. Nisar MI, et al. Influenza Other Respir Viruses. 2024 Apr;18(4):e13285. doi: 10.1111/irv.13285. Influenza Other Respir Viruses. 2024. PMID: 38616564 Free PMC article.
We describe nasopharyngeal carriage of respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and influenza virus among children with fast-breathing pneumonia in Karachi, Pakistan. ...FINDINGS: Of the 1000 children tested, 92.2% (n = 922) were positive for viral …
We describe nasopharyngeal carriage of respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and influenza virus among chi …
Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
Tretheway R, Visser V, Mollard S. Tretheway R, et al. Aust Health Rev. 2024 Apr 15. doi: 10.1071/AH23107. Online ahead of print. Aust Health Rev. 2024. PMID: 38616105
Descriptive statistics were generated for the total number of pageviews for all pages by month and year (2015-2021); for the top 15 most viewed pages in 2019, February-March 2020 inclusive (early COVID-19 pandemic period), 10-24 March 2021 (North Coast NSW region local disaster d …
Descriptive statistics were generated for the total number of pageviews for all pages by month and year (2015-2021); for the top 15 most vie …
Design, synthesis, docking, and antiviral evaluation of some novel pyrimidinone-based α-aminophosphonates as potent H1N1 and HCoV-229E inhibitors.
Hekal HA, Hammad OM, El-Brollosy NR, Salem MM, Allayeh AK. Hekal HA, et al. Bioorg Chem. 2024 Apr 8;147:107353. doi: 10.1016/j.bioorg.2024.107353. Online ahead of print. Bioorg Chem. 2024. PMID: 38615475
The new compounds were subjected to in-silico molecular docking simulations to evaluate their potential inhibition against Influenza A Neuraminidase and RNA-dependent RNA polymerase of human coronavirus 229E. Subsequently, the compounds were further tested in vitro using a …
The new compounds were subjected to in-silico molecular docking simulations to evaluate their potential inhibition against Influenza …
Vaccination Motivators and Deterrents Among Undervaccinated Older Adults in North Dakota.
Huseth-Zosel AL, Fuller H, Carson PJ. Huseth-Zosel AL, et al. J Community Health. 2024 Apr 13. doi: 10.1007/s10900-024-01351-8. Online ahead of print. J Community Health. 2024. PMID: 38615100
Despite increased risk of morbidity and mortality among older adults due to preventable infectious diseases such as influenza, shingles, pneumonia, and COVID-19, many forego receiving some, if not all, of these vaccinations. ...Reasons for remaining unvaccinated varied by …
Despite increased risk of morbidity and mortality among older adults due to preventable infectious diseases such as influenza, shingl …
Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children.
Jia JZ, Cohen CA, Gu H, McLean MR, Varadarajan R, Bhandari N, Peiris M, Leung GM, Poon LLM, Tsang T, Chung AW, Cowling BJ, Leung NHL, Valkenburg SA. Jia JZ, et al. Nat Commun. 2024 Apr 13;15(1):3210. doi: 10.1038/s41467-024-47590-0. Nat Commun. 2024. PMID: 38615070 Free PMC article. Clinical Trial.
In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal trivalent influenza vaccination in children (NCT00792051) conducted at the onset of the 2009 H1N1 pandemic (pH1N1) and monitored for infection. ...Thus, seasonal vaccination can …
In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal trivalent influenza vaccination in chi …
Differentiated impacts of short-term exposure to fine particulate constituents on infectious diseases in 507 cities of Chinese children and adolescents: A nationwide time-stratified case-crossover study from 2008 to 2021.
Chen L, Yuan W, Geng M, Xu R, Xing Y, Wen B, Wu Y, Ren X, Shi Y, Zhang Y, Song X, Qin Y, Wang R, Jiang J, Dong Z, Liu J, Guo T, Song Z, Wang L, Ma Y, Dong Y, Song Y, Ma J. Chen L, et al. Sci Total Environ. 2024 Apr 12;928:172299. doi: 10.1016/j.scitotenv.2024.172299. Online ahead of print. Sci Total Environ. 2024. PMID: 38614340
Specifically, sulfate and BC had pronounced impacts on respiratory diseases, with sulfate linked to a 10.73 % increase in seasonal influenza risk and NO(3)(-) to a 16.39 % rise in tuberculosis. Exposure to PM(2.5) also marginally increased risks for gastrointestinal, enter …
Specifically, sulfate and BC had pronounced impacts on respiratory diseases, with sulfate linked to a 10.73 % increase in seasonal influe …
Endogenous IAA affected fluoranthene accumulation by regulating H+-ATPase and SOD activity in ryegrass.
Xu Y, Li Y, Xiao Z, Zhang X, Jiao J, Zhang H, Li H, Hu F, Xu L. Xu Y, et al. Ecotoxicol Environ Saf. 2024 Apr 12;276:116315. doi: 10.1016/j.ecoenv.2024.116315. Online ahead of print. Ecotoxicol Environ Saf. 2024. PMID: 38614001 Free article.
The experimental setup included a Flu treatment group (ryegrass with Flu addition) and a control group (ryegrass without Flu). ...Moreover, Flu+AB treatment led to increased Flu accumulation, in contrast to the inhibitory effect observed with …
The experimental setup included a Flu treatment group (ryegrass with Flu addition) and a control group (ryegrass without Fl …
Curcumin as a natural potential drug candidate against important zoonotic viruses and prions: A narrative review.
Azarkar S, Abedi M, Lavasani ASO, Ammameh AH, Goharipanah F, Baloochi K, Bakhshi H, Jafari A. Azarkar S, et al. Phytother Res. 2024 Apr 12. doi: 10.1002/ptr.8119. Online ahead of print. Phytother Res. 2024. PMID: 38613154 Review.
Of 216 studies, 135 (62.5%), 24 (11.1%), and 19 (8.8%) were conducted on the effect of curcumin and curcuminoids against SARS-CoV-2, Influenza A virus, and dengue virus, respectively. This review suggests curcumin and curcuminoids as promising therapeutic agents against a …
Of 216 studies, 135 (62.5%), 24 (11.1%), and 19 (8.8%) were conducted on the effect of curcumin and curcuminoids against SARS-CoV-2, Infl …
Design and Escherichia coli Expression of a Natively Folded Multi-Disulfide Bonded Influenza H1N1-PR8 Receptor-Binding Domain (RBD).
Tu T, Rathnayaka T, Kato T, Mizutani K, Saotome T, Noguchi K, Kidokoro SI, Kuroda Y. Tu T, et al. Int J Mol Sci. 2024 Apr 1;25(7):3943. doi: 10.3390/ijms25073943. Int J Mol Sci. 2024. PMID: 38612753 Free PMC article.
Nevertheless, because of its cost-effectiveness, handiness, and versatility, the E. coli expression of viral envelope proteins, such as the RBD (Receptor-Binding Domain) of the influenza Hemagglutinin protein, could significantly advance research on viral infections. ...Ou …
Nevertheless, because of its cost-effectiveness, handiness, and versatility, the E. coli expression of viral envelope proteins, such as the …
Insights into the Adolescent Cystic Fibrosis Airway Microbiome Using Shotgun Metagenomics.
McDermott G, Walsh A, Crispie F, Frost S, Greally P, Cotter PD, O'Sullivan O, Renwick J. McDermott G, et al. Int J Mol Sci. 2024 Mar 31;25(7):3893. doi: 10.3390/ijms25073893. Int J Mol Sci. 2024. PMID: 38612702 Free PMC article.
Pathogenic sequence types (STs) of S. aureus, Pseudomonas aeruginosa, Haemophilus influenzae and Stenotrophomonas maltophilia were observed to persist in young CF patients, while STs of S. aureus were both persistent and shared between patients. ...
Pathogenic sequence types (STs) of S. aureus, Pseudomonas aeruginosa, Haemophilus influenzae and Stenotrophomonas maltophilia were ob …
The Three-Dimensional Reference Interaction Site Model Approach as a Promising Tool for Studying Hydrated Viruses and Their Complexes with Ligands.
Fedotova MV, Chuev GN. Fedotova MV, et al. Int J Mol Sci. 2024 Mar 26;25(7):3697. doi: 10.3390/ijms25073697. Int J Mol Sci. 2024. PMID: 38612508 Free PMC article. Review.
We discuss various biophysical aspects of the 3D-RISM results and demonstrate capabilities, limitations, achievements, and prospects of the method using examples of viruses such as influenza, hepatitis, and SARS-CoV-2 viruses....
We discuss various biophysical aspects of the 3D-RISM results and demonstrate capabilities, limitations, achievements, and prospects of the …
Surveillance and Genetic Analysis of Low-Pathogenicity Avian Influenza Viruses Isolated from Feces of Wild Birds in Mongolia, 2021 to 2023.
Kang YM, Tseren Ochir EO, Heo GB, An SH, Jeong H, Dondog U, Myagmarsuren T, Lee YJ, Lee KN. Kang YM, et al. Animals (Basel). 2024 Apr 4;14(7):1105. doi: 10.3390/ani14071105. Animals (Basel). 2024. PMID: 38612344 Free PMC article.
This has increased interest in monitoring and genetically analyzing avian influenza viruses (AIVs) in northern regions, such as Mongolia, which share migratory bird flyways with Korea. ...
This has increased interest in monitoring and genetically analyzing avian influenza viruses (AIVs) in northern regions, such as Mongo …
Genetic Diversity of Avian Influenza Viruses Detected in Waterbirds in Northeast Italy Using Two Different Sampling Strategies.
Graziosi G, Lupini C, Gobbo F, Zecchin B, Quaglia G, Pedrazzoli S, Lizzi G, Dosa G, Martini G, Terregino C, Catelli E. Graziosi G, et al. Animals (Basel). 2024 Mar 27;14(7):1018. doi: 10.3390/ani14071018. Animals (Basel). 2024. PMID: 38612257 Free PMC article.
Avian influenza viruses (AIVs), which circulate endemically in wild aquatic birds, pose a significant threat to poultry and raise concerns for their zoonotic potential. ...
Avian influenza viruses (AIVs), which circulate endemically in wild aquatic birds, pose a significant threat to poultry and raise con …
Lack of Highly Pathogenic Avian Influenza H5N1 in the South Shetland Islands in Antarctica, Early 2023.
Muñoz G, Mendieta V, Ulloa M, Agüero B, Torres CG, Kruger L, Neira V. Muñoz G, et al. Animals (Basel). 2024 Mar 26;14(7):1008. doi: 10.3390/ani14071008. Animals (Basel). 2024. PMID: 38612247 Free PMC article.
In January 2023, an active surveillance initiative was undertaken in the South Shetland Islands, Antarctica, with the specific objective of ascertaining evidence for the presence of avian influenza, and specifically the highly pathogenic avian influenza virus subtyp …
In January 2023, an active surveillance initiative was undertaken in the South Shetland Islands, Antarctica, with the specific objective of …
Sputtering-Deposited Ultra-Thin Ag-Cu Films on Non-Woven Fabrics for Face Masks with Antimicrobial Function and Breath NOx Response.
Huang X, Hu Q, Li J, Yao W, Wang C, Feng Y, Song W. Huang X, et al. Materials (Basel). 2024 Mar 29;17(7):1574. doi: 10.3390/ma17071574. Materials (Basel). 2024. PMID: 38612088 Free PMC article.
The antibacterial rates against Escherichia coli and Staphylococcus aureus were 99.996% and 99.978%, respectively, while the antiviral activity against influenza A virus H1N1 was 99.02%. Furthermore, the mask's ability to monitor respiratory system diseases was achieved th …
The antibacterial rates against Escherichia coli and Staphylococcus aureus were 99.996% and 99.978%, respectively, while the antiviral activ …
Epidemiological Characterization of Respiratory Pathogens Using the Multiplex PCR FilmArray™ Respiratory Panel.
Hong YJ, Jung BK, Kim JK. Hong YJ, et al. Diagnostics (Basel). 2024 Mar 29;14(7):734. doi: 10.3390/diagnostics14070734. Diagnostics (Basel). 2024. PMID: 38611647 Free PMC article.
Results revealed adenovirus as the most prevalent pathogen (18.9%), followed by influenza virus A (16.5%), among others. Notably, a 22.5% co-infection rate was observed. ...
Results revealed adenovirus as the most prevalent pathogen (18.9%), followed by influenza virus A (16.5%), among others. Notably, a 2 …
Clinical Evaluation of Xpert Xpress CoV-2/Flu/RSV plus and Alinity m Resp-4-Plex Assay.
Chan WS, Wong KP, Yau SK, Wong CY, Chan TC, Hung J, Lai KT, Leung CP, Wang CL, Au CH, Wan TS, Ma ES, Tang BS. Chan WS, et al. Diagnostics (Basel). 2024 Mar 24;14(7):683. doi: 10.3390/diagnostics14070683. Diagnostics (Basel). 2024. PMID: 38611596 Free PMC article.
For respiratory specimens, CoV-2/Flu/RSV plus exhibited perfect agreement with the standard-of-care (SOC) methods (Cohen's kappa: 1, 100% agreement). ...The experimental limit of detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the lowest (25 c …
For respiratory specimens, CoV-2/Flu/RSV plus exhibited perfect agreement with the standard-of-care (SOC) methods (Cohen's kappa: 1, …
Design and Preclinical Evaluation of a Novel Prostate-Specific Membrane Antigen Radioligand Modified with a Transthyretin Binder.
Vaccarin C, Mapanao AK, Deberle LM, Becker AE, Borgna F, Marzaro G, Schibli R, Müller C. Vaccarin C, et al. Cancers (Basel). 2024 Mar 23;16(7):1262. doi: 10.3390/cancers16071262. Cancers (Basel). 2024. PMID: 38610940 Free PMC article.
A high and specific uptake of [(177)Lu]Lu-PSMA-TB-01 was found in PSMA-positive PC-3 PIP cells (69 3% after 4 h incubation), while uptake in PSMA-negative PC-3 flu cells was negligible (<1%). In vitro binding studies showed a 174-fold stronger affinity of [(177)Lu]Lu-PS …
A high and specific uptake of [(177)Lu]Lu-PSMA-TB-01 was found in PSMA-positive PC-3 PIP cells (69 3% after 4 h incubation), while uptake in …
Infodemiology of Influenza-like Illness: Utilizing Google Trends' Big Data for Epidemic Surveillance.
Shih DH, Wu YH, Wu TW, Chang SC, Shih MH. Shih DH, et al. J Clin Med. 2024 Mar 27;13(7):1946. doi: 10.3390/jcm13071946. J Clin Med. 2024. PMID: 38610711 Free PMC article.
Background: Influenza-like illness (ILI) encompasses symptoms similar to influenza, affecting population health. ...Methods: This study used multiple regression models to analyze the correlation between ILI incidents, GT keyword searches, and climate variables durin …
Background: Influenza-like illness (ILI) encompasses symptoms similar to influenza, affecting population health. ...Methods: T …
Personalized Assessment of Mortality Risk and Hospital Stay Duration in Hospitalized Patients with COVID-19 Treated with Remdesivir: A Machine Learning Approach.
Ramón A, Bas A, Herrero S, Blasco P, Suárez M, Mateo J. Ramón A, et al. J Clin Med. 2024 Mar 22;13(7):1837. doi: 10.3390/jcm13071837. J Clin Med. 2024. PMID: 38610602 Free PMC article.
Factors associated with worse outcomes in terms of mortality included limitations in life support, ventilatory support needs, lymphopenia, low albumin and hemoglobin levels, flu and/or coinfection, and cough. For hospital stay, factors included vaccine doses, lung density, …
Factors associated with worse outcomes in terms of mortality included limitations in life support, ventilatory support needs, lymphopenia, l …
Relationships between the Structural Characteristics of General Medical Practices and the Socioeconomic Status of Patients with Diabetes-Related Performance Indicators in Primary Care.
Jargalsaikhan U, Kasabji F, Vincze F, Pálinkás A, Kőrösi L, Sándor J. Jargalsaikhan U, et al. Healthcare (Basel). 2024 Mar 22;12(7):704. doi: 10.3390/healthcare12070704. Healthcare (Basel). 2024. PMID: 38610127 Free PMC article.
A lower level of education (hemoglobin A1c test: beta = -0.108; ophthalmic examination: beta = -0.100; serum creatinine test: beta = -0.103; and serum lipid status test: beta = -0.108) and large GMP size (hemoglobin A1c test: beta = -0.068; ophthalmological examination beta = -0. …
A lower level of education (hemoglobin A1c test: beta = -0.108; ophthalmic examination: beta = -0.100; serum creatinine test: beta = -0.103; …
Impact of health education on promoting influenza vaccination health literacy in primary school students: a cluster randomised controlled trial protocol.
Xie W, Xiao J, Chen J, Huang H, Huang X, He S, Xu L. Xie W, et al. BMJ Open. 2024 Apr 12;14(4):e080115. doi: 10.1136/bmjopen-2023-080115. BMJ Open. 2024. PMID: 38609315 Free article.
INTRODUCTION: Influenza is a major public health threat, and vaccination is the most effective prevention method. ...The primary outcome is the influenza vaccination rate. Secondary outcomes include health literacy levels, influenza diagnosis rate, influen …
INTRODUCTION: Influenza is a major public health threat, and vaccination is the most effective prevention method. ...The primary outc …
Discovery andsynthesis of novel benzoylhydrazone neuraminidase inhibitors.
Fu SK, Cheng LP. Fu SK, et al. Bioorg Med Chem Lett. 2024 Apr 11;105:129743. doi: 10.1016/j.bmcl.2024.129743. Online ahead of print. Bioorg Med Chem Lett. 2024. PMID: 38608962
Neuraminidase (NA) serves as a promising target for the exploration and development of anti-influenza drugs. In this work, lead compound 5 was discovered through pharmacophore-based virtual screening and molecular dynamics simulation, and 14 new compounds were obtained by …
Neuraminidase (NA) serves as a promising target for the exploration and development of anti-influenza drugs. In this work, lead compo …
Accurate and reliable surface-enhanced Raman spectroscopy assay for early detection of SARS-CoV-2 RNA with exceptional sensitivity.
Awad H, El-Brolossy TA, Abdallah T, Osman A, Negm S, Mansour OI, Girgis SA, Hafez HM, Zaki AM, Talaat H. Awad H, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Mar 26;315:124184. doi: 10.1016/j.saa.2024.124184. Online ahead of print. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38608556
It has good selectivity in discriminating SARS-CoV-2 RNA against other respiratory viruses, respiratory syncytial virus (RSV), and influenza A virus. The reliability of the assay was validated by testing 24 clinical samples, including 12 positive samples with varying cycle …
It has good selectivity in discriminating SARS-CoV-2 RNA against other respiratory viruses, respiratory syncytial virus (RSV), and influe …
Omicron variants of SARS-CoV-2: Epidemiological and clinical insights from a tertiary care center in Saudi Arabia.
Dubaie B, Aldayel A, Alwethinani S, Alhuthil R, Alhamlan F, Alghamdi S, Alsuhaibani M, Aljumaah S, AlYabes O, AlBanyan E, Al-Hajjar S. Dubaie B, et al. J Infect Public Health. 2024 Apr 6;17(6):961-966. doi: 10.1016/j.jiph.2024.04.003. Online ahead of print. J Infect Public Health. 2024. PMID: 38608457 Free article.
Notably, in December, only one XBB case was reported, and 62 instances emerged with the JN variant. Overall, 233 out of 305 cases were reported during flu season (September to March) (76.39 %). Moreover, hospitalization occurred in (16.39 %), with a (1.31 %) mortality rate …
Notably, in December, only one XBB case was reported, and 62 instances emerged with the JN variant. Overall, 233 out of 305 cases were repor …
Adjuvant-free parenterally injectable vaccine platform that harnesses previously induced IgG as an antigen delivery carrier.
Kawai A, Hirata H, Tokunoh N, Ono C, Matsuura Y, Hirai T, Yoshioka Y. Kawai A, et al. Biochem Biophys Res Commun. 2024 Apr 7;711:149919. doi: 10.1016/j.bbrc.2024.149919. Online ahead of print. Biochem Biophys Res Commun. 2024. PMID: 38608435
We generated RBD-HA by combining the receptor binding domain (RBD) derived from SARS-CoV-2 as a vaccine antigen with hemagglutinin (HA) sourced from influenza viruses to serve as the carrier protein. We revealed that subcutaneous vaccination with RBD-HA effectively trigger …
We generated RBD-HA by combining the receptor binding domain (RBD) derived from SARS-CoV-2 as a vaccine antigen with hemagglutinin (HA) sour …
Long-term variations of urban-Rural disparities in infectious disease burden of over 8.44 million children, adolescents, and youth in China from 2013 to 2021: An observational study.
Chen L, Xing Y, Zhang Y, Xie J, Su B, Jiang J, Geng M, Ren X, Guo T, Yuan W, Ma Q, Chen M, Cui M, Liu J, Song Y, Wang L, Dong Y, Ma J. Chen L, et al. PLoS Med. 2024 Apr 12;21(4):e1004374. doi: 10.1371/journal.pmed.1004374. eCollection 2024 Apr. PLoS Med. 2024. PMID: 38607981 Free PMC article.

From 2013 to 2021, this disparity was primarily driven by higher incidences of pertussis (IRR: 1.782, 95% CI [1.705, 1.862]; p < 0.001) and seasonal influenza (IRR: 3.213, 95% CI [3.205, 3.220]; p < 0.001) among vaccine-preventable diseases, tuberculosis (IRR: 1.011,

…

From 2013 to 2021, this disparity was primarily driven by higher incidences of pertussis (IRR: 1.782, 95% CI [1.705, 1.862]; p < 0.001) a

…
Sepsis-related mortality: long-term trends in Northeastern Italy, including pandemic years.
Fedeli U, Barbiellini Amidei C, Tacconelli E, Carrara E. Fedeli U, et al. Infect Dis (Lond). 2024 Apr 12:1-8. doi: 10.1080/23744235.2024.2340728. Online ahead of print. Infect Dis (Lond). 2024. PMID: 38607235
Sharp peaks in monthly mortality were observed in correspondence with flu epidemics, COVID-19 pandemic waves, and periods of extreme heat. ...
Sharp peaks in monthly mortality were observed in correspondence with flu epidemics, COVID-19 pandemic waves, and periods of extreme …
Ex Pluribus Unum: The CD4 T Cell Response against Influenza A Virus.
Finn CM, McKinstry KK. Finn CM, et al. Cells. 2024 Apr 5;13(7):639. doi: 10.3390/cells13070639. Cells. 2024. PMID: 38607077 Free PMC article. Review.
Current Influenza A virus (IAV) vaccines, which primarily aim to generate neutralizing antibodies against the major surface proteins of specific IAV strains predicted to circulate during the annual 'flu' season, are suboptimal and are characterized by relatively low …
Current Influenza A virus (IAV) vaccines, which primarily aim to generate neutralizing antibodies against the major surface proteins …
The role of viral diagnostic tests in respiratory tract infections: moving forward.
Ortíz de Lejarazu R, Eiros JM, López-Medrano F, Montes M, Tagarro A, Tomás M. Ortíz de Lejarazu R, et al. Rev Esp Quimioter. 2024 Apr 12:ortiz12apr2024. doi: 10.37201/req/150.2023. Online ahead of print. Rev Esp Quimioter. 2024. PMID: 38606841 Free article.
In order to further understand the role of viral diagnostic tests in the management of RTI, a panel of experts was convened to discuss about their potential role, beyond what had been agreed in Influenza. The objective of this panel was to define the plausible role of aeti …
In order to further understand the role of viral diagnostic tests in the management of RTI, a panel of experts was convened to discuss about …
Excess mortality in Europe coincides with peaks of COVID-19, influenza and respiratory syncytial virus (RSV), November 2023 to February 2024.
Nørgaard SK, Nielsen J, Nordholm AC, Richter L, Chalupka A, Sierra NB, Braeye T, Athanasiadou M, Lytras T, Denissov G, Luomala O, Fouillet A, Pontais I, An der Heiden M, Zacher B, Weigel A, Foppa I, Gkolfinopoulou K, Panagoulias I, Paldy A, Malnasi T, Domegan L, Kelly E, Rotem N, Rakhlin O, de'Donato FK, Di Blasi C, Hoffmann P, Velez T, England K, Calleja N, van Asten L, Jongenotter F, Rodrigues AP, Silva S, Klepac P, Gomez-Barroso D, Gomez IL, Galanis I, Farah A, Weitkunat R, Fehst K, Andrews N, Clare T, Bradley DT, O'Doherty MG, William N, Hamilton M, Søborg B, Krause TG, Bundle N, Vestergaard LS. Nørgaard SK, et al. Euro Surveill. 2024 Apr;29(15):2400178. doi: 10.2807/1560-7917.ES.2024.29.15.2400178. Euro Surveill. 2024. PMID: 38606570 Free PMC article.
This excess mortality is seen in adults aged 45 years and older, and coincides with widespread presence of COVID-19, influenza and respiratory syncytial virus (RSV) observed in many European countries during the 2023/24 winter season....
This excess mortality is seen in adults aged 45 years and older, and coincides with widespread presence of COVID-19, influenza and re …
Rate of severe and fatal infections in a cohort of patients with interstitial lung disease associated with rheumatoid arthritis: a multicenter prospective study.
Mena-Vázquez N, Redondo-Rodriguez R, Rojas-Gimenez M, Romero-Barco CM, Fuego-Varela C, Perez-Gómez N, Añón-Oñate I, Castro Pérez P, García-Studer A, Hidalgo-Conde A, Arnedo Díez de Los Ríos R, Cabrera-César E, Velloso-Feijoo ML, Manrique-Arija S, Calvo-Gutiérrez J, Gandía-Martínez M, Morales-Garrido P, Godoy-Navarrete FJ, Mouriño-Rodriguez C, Espildora F, Aguilar-Hurtado MC, Fernández-Nebro A. Mena-Vázquez N, et al. Front Immunol. 2024 Mar 28;15:1341321. doi: 10.3389/fimmu.2024.1341321. eCollection 2024. Front Immunol. 2024. PMID: 38605950 Free PMC article.
Respiratory infections were the most common first infection (74%), infection overall (74%), and fatal infection (80%) and were caused mostly by SARS CoV-2, Streptococcus pneumoniae, Pseudomonas aeruginosa, and influenza A virus. The factors associated with an increased ris …
Respiratory infections were the most common first infection (74%), infection overall (74%), and fatal infection (80%) and were caused mostly …
Cecropin AD reduces viral load and inflammatory response against H9N2 avian influenza virus in chickens.
Zhang T, Liu Z, Zhi Y, Zhao X, Du M, Zhang Q, Zhang T, Hu G. Zhang T, et al. Front Vet Sci. 2024 Mar 28;11:1369863. doi: 10.3389/fvets.2024.1369863. eCollection 2024. Front Vet Sci. 2024. PMID: 38605918 Free PMC article.
INTRODUCTION: This study focuses on evaluating the therapeutic efficacy of cecropin AD, an antimicrobial peptide, against H9N2 avian influenza virus (AIV) in chickens. Given the global impact of H9N2 AIV on poultry health, identifying effective treatments is crucial. ...
INTRODUCTION: This study focuses on evaluating the therapeutic efficacy of cecropin AD, an antimicrobial peptide, against H9N2 avian infl …
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