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100 results

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Quoted phrase not found in phrase index: "Injection site pigmentation changes"
Page 1
Safety and efficacy of MCO-010 optogenetic therapy in patients with Stargardt disease in USA (STARLIGHT): an open-label multi-center Ph2 trial.
Lam BL, Zak V, Gonzalez VH, Gregori NZ, Chavala SH, Batabyal S, Carlson M, Kim S, Ayyagari A, Chang J, Lane H, Choudry N, Koester J, Von Tress M, Piltz-Seymour J, Sharif NA, Tsang SH, Mahajan VB, Boyer DS, Ho AC, Barone SB, Mohanty SK. Lam BL, et al. EClinicalMedicine. 2025 Aug 14;87:103430. doi: 10.1016/j.eclinm.2025.103430. eCollection 2025 Sep. EClinicalMedicine. 2025. PMID: 40838197 Free PMC article.
The BCVA (mean SD) of the six treated eyes at baseline and 48-week follow-up was 22.8 9.87 (range 9-35), and 28.3 13.28 (range 4-42) ETDRS letters, respectively. The BCVA change from baseline was 7.2 11.74, 4.2 14.81, and 5.5 12.29 at 12, 24, and 48 weeks, resp …
The BCVA (mean SD) of the six treated eyes at baseline and 48-week follow-up was 22.8 9.87 (range 9-35), and 28.3 13.28 (range 4-42) E …
Irinotecan-Induced Site-Specific Pigmentation in the Plantar Region of Mice.
Imai M, Hiramoto K, Tanaka S, Okayama M, Ooi K. Imai M, et al. Biol Pharm Bull. 2025;48(2):108-114. doi: 10.1248/bpb.b24-00662. Biol Pharm Bull. 2025. PMID: 39909437 Free article.
In this study, we investigated the pigmentation-related effects of irinotecan in colored hairless mice. Mice received intraperitoneal injections of 20 mg/kg irinotecan, and we subsequently examined the pigmentation of the plantar and buttock regions. ...Furth …
In this study, we investigated the pigmentation-related effects of irinotecan in colored hairless mice. Mice received intraperitoneal …
The histopathology of drugs of abuse.
Milroy CM, Parai JL. Milroy CM, et al. Histopathology. 2011 Oct;59(4):579-93. doi: 10.1111/j.1365-2559.2010.03728.x. Epub 2011 Jan 25. Histopathology. 2011. PMID: 21261690 Review.
Crack cocaine use is also associated with changes in the pulmonary system, including carbon pigmented intra-alveolar macrophages, emphysema and pulmonary arterial changes. Cannabis use is associated with brown pigmented macrophages in the lung as well …
Crack cocaine use is also associated with changes in the pulmonary system, including carbon pigmented intra-alveolar macrophag …
Dose-Dependent Progression of Chorioretinal Atrophy at the Injection Site After Subretinal Injection of rAAV2/8 in Nonhuman Primates.
Seitz IP, Wozar F, Ochakovski GA, Reichel FF, Gelisken F, Bartz-Schmidt KU, Peters T, Fischer MD. Seitz IP, et al. Ophthalmol Sci. 2024 Mar 15;4(5):100516. doi: 10.1016/j.xops.2024.100516. eCollection 2024 Sep-Oct. Ophthalmol Sci. 2024. PMID: 38881604 Free PMC article.
Area [mm(2)] of hyperfluorescence in fluorescence angiography and hypofluorescence in indocyanine green angiography. RESULTS: Progressive atrophy at the injection site developed in 54% of high-dose-treated, 27% of low-dose-treated, and 0% of sham-treated eyes. ...Ra …
Area [mm(2)] of hyperfluorescence in fluorescence angiography and hypofluorescence in indocyanine green angiography. RESULTS: Progressive at …
CRYAA activates the SIRT1-pi3K/AKT signaling pathway by suppressing mir-155-5p to protect the RPE.
Yang W, Lu B, Chen Q, Wang J, Zhou J, Li R, Lin Y, Zhang J. Yang W, et al. Arch Biochem Biophys. 2025 Aug;770:110435. doi: 10.1016/j.abb.2025.110435. Epub 2025 May 9. Arch Biochem Biophys. 2025. PMID: 40350053 Free article.
BACKGROUND: Retinal degenerative diseases are important causes of blindness, and their pathogenesis is related to degenerative changes in the retinal pigment epithelium (RPE). alphaA-Crystallin (CRYAA) plays a role in maintaining cellular protein homeostasis and has …
BACKGROUND: Retinal degenerative diseases are important causes of blindness, and their pathogenesis is related to degenerative changes …
Cutaneous manifestations of non-Hodgkin's lymphoma.
Kumar SS, Kuruvilla M, Pai GS, Dinesh M. Kumar SS, et al. Indian J Dermatol Venereol Leprol. 2003 Jan-Feb;69(1):12-5. Indian J Dermatol Venereol Leprol. 2003. PMID: 17642814
When compared to control patients only acquired ichthyosis and generalised pruritus were found to be statistically significant. The study group also showed changes due to chemotherapy like diffuse alopecia (24/29), bluish pigmentation of proximal part of nail (4/29) …
When compared to control patients only acquired ichthyosis and generalised pruritus were found to be statistically significant. The study gr …
Cold Atmospheric Plasma-Activated In Situ Hydrogel Induces Hair Regeneration Via Immune Microenvironment Remodeling.
Kim JS, Byun J, Choi J, Jin D, Li Q, Lee J, Choi HG, Oh YK. Kim JS, et al. Adv Sci (Weinh). 2026 Jan;13(5):e11962. doi: 10.1002/advs.202511962. Epub 2025 Nov 9. Adv Sci (Weinh). 2026. PMID: 41208290 Free PMC article.
CAP irradiation induces the gelation of a tyramine-grafted hyaluronic acid solution containing interleukin-2 (HTsol/IL2), forming a hydrogel (CAPgel/IL2) that retains CAP-induced reactive oxygen species and IL2 within its matrix. In vivo, subcutaneous injection of HTsol/IL …
CAP irradiation induces the gelation of a tyramine-grafted hyaluronic acid solution containing interleukin-2 (HTsol/IL2), forming a hydrogel …
TRPA1 for Butterfly Eyespot Formation.
Ozaki M, Otaki JM. Ozaki M, et al. Int J Mol Sci. 2026 Jan 30;27(3):1420. doi: 10.3390/ijms27031420. Int J Mol Sci. 2026. PMID: 41683840 Free PMC article.
Using the blue pansy butterfly Junonia orithya, we injected the TRPA1 antagonists, AM0902 and AP-18, and an agonist, JT010, into pupae and observed that the eyespot core disk area in adult wings increased and decreased in response to AM0902 and JT010, respectively, althoug …
Using the blue pansy butterfly Junonia orithya, we injected the TRPA1 antagonists, AM0902 and AP-18, and an agonist, JT010, into pupa …
Poly-L-Lactic Acid (PLLA-SCA) as a Safe and Effective Method to Soften Transition Between Lower Eyelid and Midface.
Montes JR, Rohrich RJ, Meckfessel MH, Le JHTD. Montes JR, et al. J Drugs Dermatol. 2025 Jul 1;24(7):692-694. doi: 10.36849/JDD.9003. J Drugs Dermatol. 2025. PMID: 40627579
Skin thinning, fat atrophy, along with pigmentation, skin texture, and shadow changes contribute to the "tired" look of the area. ...The aim of this case series is to discuss the technique to improve maxilla/malar projection, pigmentation, texture, and volume …
Skin thinning, fat atrophy, along with pigmentation, skin texture, and shadow changes contribute to the "tired" look of the ar …
[Polypoidal choroidal vasculopathy].
Yuzawa M. Yuzawa M. Nippon Ganka Gakkai Zasshi. 2012 Mar;116(3):200-31; discussion 232. doi: 10.4264/numa.71.282. Nippon Ganka Gakkai Zasshi. 2012. PMID: 22568102 Review. Japanese.
Polypoidal choroidal vasculopathy (PCV) is characterized by a branching vascular network with polypoidal lesions under the retinal pigment epithelium (RPE). In Japan, it is classified as a specific form of exudative age-related macular degeneration. ...The high reflective …
Polypoidal choroidal vasculopathy (PCV) is characterized by a branching vascular network with polypoidal lesions under the retinal pigmen …
100 results