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Year Number of Results
1986 1
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27 results

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Page 1
Traumatic Corneal Abrasion.
Fusco N, Stead TG, Lebowitz D, Ganti L. Fusco N, et al. Cureus. 2019 Apr 5;11(4):e4396. doi: 10.7759/cureus.4396. Cureus. 2019. PMID: 31223554 Free PMC article.
However, if there is any suspicion for penetrating eye injury, corneal ulcer, a sight-threatening infection such as bacterial keratitis, or ophthalmic zoster, an emergent referral is imperative. ...
However, if there is any suspicion for penetrating eye injury, corneal ulcer, a sight-threatening infection such as bacterial …
An alkali-burn injury model of corneal neovascularization in the mouse.
Anderson C, Zhou Q, Wang S. Anderson C, et al. J Vis Exp. 2014 Apr 7;(86):51159. doi: 10.3791/51159. J Vis Exp. 2014. PMID: 24748032 Free PMC article.
In order to develop safe, effective, and targeted therapies, a reliable model of corneal NV and pharmacological intervention is required. Here, we describe an alkali-burn injury corneal neovascularization model in the mouse. This protocol provides a method for the a …
In order to develop safe, effective, and targeted therapies, a reliable model of corneal NV and pharmacological intervention is required. He …
Neprilysin inhibition promotes corneal wound healing.
Genova RM, Meyer KJ, Anderson MG, Harper MM, Pieper AA. Genova RM, et al. Sci Rep. 2018 Sep 26;8(1):14385. doi: 10.1038/s41598-018-32773-9. Sci Rep. 2018. PMID: 30258206 Free PMC article.
Histological examination revealed increased corneal innervation in NEP(-/-) mice. In an alkali burn model of corneal injury, corneal wound healing was significantly accelerated in NEP(-/-) mice compared to WT controls 3 days after injury. ...Collectively, our …
Histological examination revealed increased corneal innervation in NEP(-/-) mice. In an alkali burn model of corneal injury, …
Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model.
Wilkerson JL, Basu SK, Stiles MA, Prislovsky A, Grambergs RC, Nicholas SE, Karamichos D, Allegood JC, Proia RL, Mandal N. Wilkerson JL, et al. Cells. 2022 Sep 17;11(18):2914. doi: 10.3390/cells11182914. Cells. 2022. PMID: 36139489 Free PMC article.
Here, we show that ablation of SphK1 can significantly reduce NV invasion in the cornea following injury. Corneal sphingolipid analysis showed that total levels of ceramides, monohexosyl ceramides (HexCer), and sphingomyelin were significantly elevated in Sphk(-/-) …
Here, we show that ablation of SphK1 can significantly reduce NV invasion in the cornea following injury. Corneal sphingolipid …
Involvement of NADPH oxidases in alkali burn-induced corneal injury.
Gu XJ, Liu X, Chen YY, Zhao Y, Xu M, Han XJ, Liu QP, Yi JL, Li JM. Gu XJ, et al. Int J Mol Med. 2016 Jul;38(1):75-82. doi: 10.3892/ijmm.2016.2594. Epub 2016 May 17. Int J Mol Med. 2016. PMID: 27221536 Free PMC article.
DPI or Apo prevented the infiltration of CD11b-positive inflammatory cells, and inhibited the transcription of inflammatory cytokines following alkali burn-induced corneal injury. In our mouse model of alkali burn-induced corneal injury, corneal …
DPI or Apo prevented the infiltration of CD11b-positive inflammatory cells, and inhibited the transcription of inflammatory cytokines follow …
Sensory Restoration of the Facial Region.
Liu X, Daugherty R, Konofaos P. Liu X, et al. Ann Plast Surg. 2019 Jun;82(6):700-707. doi: 10.1097/SAP.0000000000001635. Ann Plast Surg. 2019. PMID: 30557178 Review.
Temporary or permanent damage can lead to numbness, lip-biting injury, corneal anesthesia, and, in the worst scenario, even blindness. Different age groups, mechanisms of the injury, and the time between injury and repair can affect the final result of the nerve rep …
Temporary or permanent damage can lead to numbness, lip-biting injury, corneal anesthesia, and, in the worst scenario, even bl …
Deletion of the FHL2 gene attenuating neovascularization after corneal injury.
Chu PH, Yeh LK, Lin HC, Jung SM, Ma DH, Wang IJ, Wu HH, Shiu TF, Chen J. Chu PH, et al. Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5314-8. doi: 10.1167/iovs.08-2209. Epub 2008 Aug 15. Invest Ophthalmol Vis Sci. 2008. PMID: 18708619 Free PMC article.
METHODS: FHL2-LacZ knock-in mice were used to trace FHL2 gene expression before and after corneal injury. Corneal angiogenesis between FHL2-null mice and wild-type mice that underwent chemical and mechanical denudation of corneal and limbal epithelium were co …
METHODS: FHL2-LacZ knock-in mice were used to trace FHL2 gene expression before and after corneal injury. Corneal angio …
Quantitative characterization of acid- and alkali-induced corneal injury in the low-volume eye test.
Jester JV, Molai A, Petroll WM, Parker RD, Carr GJ, Cavanagh HD, Maurer JK. Jester JV, et al. Toxicol Pathol. 2000 Sep-Oct;28(5):668-78. doi: 10.1177/019262330002800506. Toxicol Pathol. 2000. PMID: 11026602
In the following studies we characterized the extent of corneal injury following exposure to different concentrations of acetic acid and sodium hydroxide (NaOH) in the rabbit low-volume eye test. ...Quantitative assessment of macroscopic scores, corneal surface epit …
In the following studies we characterized the extent of corneal injury following exposure to different concentrations of aceti …
Postoperative Corneal Injuries: Incidence and Risk Factors.
Deljou A, Weingarten TN, Mahr MA, Sprung J, Martin DP. Deljou A, et al. Anesth Analg. 2019 Sep;129(3):737-742. doi: 10.1213/ANE.0000000000003710. Anesth Analg. 2019. PMID: 31425215
BACKGROUND: Previous studies of postoperative corneal injury rates relied on provider-initiated incident reports, which may underestimate the true incidence. ...CONCLUSIONS: Calculation of incidence by using the administration of a medication (proparacaine eye drops …
BACKGROUND: Previous studies of postoperative corneal injury rates relied on provider-initiated incident reports, which may un …
Long-term recovery of the human corneal endothelium after toxic injury by benzalkonium chloride.
Hughes EH, Pretorius M, Eleftheriadis H, Liu CS. Hughes EH, et al. Br J Ophthalmol. 2007 Nov;91(11):1460-3. doi: 10.1136/bjo.2006.109439. Epub 2007 May 15. Br J Ophthalmol. 2007. PMID: 17504856 Free PMC article.
Mean central corneal endothelial cell density (n = 3) increased 28% from 663.7 cells/mm(2) at one year to 835.7 cells/mm(2) (p<0.05). CONCLUSIONS: After toxic injury, corneal endothelial function may have a remarkable capacity for recovery even after the first po …
Mean central corneal endothelial cell density (n = 3) increased 28% from 663.7 cells/mm(2) at one year to 835.7 cells/mm(2) (p<0.05). CON …
27 results