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Year Number of Results
1875 1
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1877 1
1878 1
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1880 1
1881 9
1882 6
1883 4
1884 4
1885 8
1886 4
1887 6
1888 6
1889 7
1890 7
1891 10
1892 7
1893 6
1894 7
1895 3
1896 2
1897 7
1898 11
1899 18
1900 10
1901 14
1902 8
1903 13
1904 4
1905 12
1906 7
1907 4
1908 10
1909 12
1910 8
1911 15
1912 13
1913 15
1914 27
1915 20
1916 34
1917 35
1918 34
1919 29
1920 24
1921 30
1922 39
1923 43
1924 41
1925 42
1926 48
1927 32
1928 34
1929 36
1930 41
1931 37
1932 44
1933 43
1934 46
1935 48
1936 54
1937 42
1938 42
1939 42
1940 56
1941 53
1942 42
1943 51
1944 41
1945 465
1946 1293
1947 1548
1948 1372
1949 1448
1950 2001
1951 1986
1952 2166
1953 2572
1954 2713
1955 2894
1956 2796
1957 2860
1958 2961
1959 3035
1960 3115
1961 3556
1962 3858
1963 5326
1964 6893
1965 6372
1966 6725
1967 8416
1968 10188
1969 11097
1970 11428
1971 12710
1972 14723
1973 15189
1974 15645
1975 15366
1976 15260
1977 15430
1978 15643
1979 16672
1980 17275
1981 17598
1982 18811
1983 19538
1984 21048
1985 22378
1986 22863
1987 23335
1988 24122
1989 27030
1990 28034
1991 28537
1992 29015
1993 28784
1994 30069
1995 30900
1996 30942
1997 31814
1998 33178
1999 34657
2000 37793
2001 40256
2002 41866
2003 44593
2004 48081
2005 52983
2006 56228
2007 60083
2008 62962
2009 66030
2010 70520
2011 75737
2012 80479
2013 83578
2014 86211
2015 87847
2016 88543
2017 90200
2018 93043
2019 97461
2020 106179
2021 109356
2022 110227
2023 105123
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2025 18984

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2,473,163 results

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Page 1
Lipopolysaccharide endotoxins.
Raetz CR, Whitfield C. Raetz CR, et al. Annu Rev Biochem. 2002;71:635-700. doi: 10.1146/annurev.biochem.71.110601.135414. Epub 2001 Nov 9. Annu Rev Biochem. 2002. PMID: 12045108 Free PMC article. Review.
Many enzymes of lipid A biosynthesis like LpxC have been validated as targets for development of new antibiotics. Key genes for lipid A biosynthesis have unexpectedly also been found in higher plants, indicating that eukaryotic lipid A-li …
Many enzymes of lipid A biosynthesis like LpxC have been validated as targets for development of new antibiotics. Key genes fo …
Lipopolysaccharide modification in Gram-negative bacteria during chronic infection.
Maldonado RF, Sá-Correia I, Valvano MA. Maldonado RF, et al. FEMS Microbiol Rev. 2016 Jul;40(4):480-93. doi: 10.1093/femsre/fuw007. Epub 2016 Apr 12. FEMS Microbiol Rev. 2016. PMID: 27075488 Free PMC article. Review.
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer membrane that plays a key role in host-pathogen interactions with the innate immune system. During infection, bacteria are exposed to a host environment that is typically dominate …
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer membrane that plays a key role in host-pathoge …
Function and Biogenesis of Lipopolysaccharides.
Bertani B, Ruiz N. Bertani B, et al. EcoSal Plus. 2018 Aug;8(1):10.1128/ecosalplus.ESP-0001-2018. doi: 10.1128/ecosalplus.ESP-0001-2018. EcoSal Plus. 2018. PMID: 30066669 Free PMC article. Review.
One of the most studied bacterial surface molecules is the glycolipid known as lipopolysaccharide (LPS), which is produced by most Gram-negative bacteria. Much of the initial attention LPS received in the early 1900s was owed to its ability to stimulat …
One of the most studied bacterial surface molecules is the glycolipid known as lipopolysaccharide (LPS), which is produced by most …
Mechanisms of Polymyxin Resistance.
Moffatt JH, Harper M, Boyce JD. Moffatt JH, et al. Adv Exp Med Biol. 2019;1145:55-71. doi: 10.1007/978-3-030-16373-0_5. Adv Exp Med Biol. 2019. PMID: 31364071 Review.
Most identified polymyxin resistance mechanisms in Gram-negative bacteria involve changes to the lipopolysaccharide (LPS) structure, as polymyxins initially interact with the negatively charged lipid A component of LPS. ...Uniquely, Acine …
Most identified polymyxin resistance mechanisms in Gram-negative bacteria involve changes to the lipopolysaccharide
Lipopolysaccharide: Biosynthetic pathway and structure modification.
Wang X, Quinn PJ. Wang X, et al. Prog Lipid Res. 2010 Apr;49(2):97-107. doi: 10.1016/j.plipres.2009.06.002. Epub 2009 Oct 6. Prog Lipid Res. 2010. PMID: 19815028 Review.
Lipopolysaccharide that constitutes the outer leaflet of the outer membrane of most Gram-negative bacteria is referred to as an endotoxin. ...Most enzymes and genes coding for proteins responsible for the biosynthesis and export of lipopolysaccharid
Lipopolysaccharide that constitutes the outer leaflet of the outer membrane of most Gram-negative bacteria is re
Recognition of lipopolysaccharide pattern by TLR4 complexes.
Park BS, Lee JO. Park BS, et al. Exp Mol Med. 2013 Dec 6;45(12):e66. doi: 10.1038/emm.2013.97. Exp Mol Med. 2013. PMID: 24310172 Free PMC article. Review.
Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. ...The common structural pattern of LPS in diverse bacterial species is recognized by a cascade of LPS receptors and accessory proteins, LPS binding protein
Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. ...The common str
ApoE Lipidation as a Therapeutic Target in Alzheimer's Disease.
Lanfranco MF, Ng CA, Rebeck GW. Lanfranco MF, et al. Int J Mol Sci. 2020 Sep 1;21(17):6336. doi: 10.3390/ijms21176336. Int J Mol Sci. 2020. PMID: 32882843 Free PMC article. Review.
Here we highlight the importance of lipidated apoE as well as the APOE-lipidation targeted therapeutic approaches that have the potential to correct or prevent neurodegeneration. ...Overall, there is great potential to improve the lipidated state of apoE with …
Here we highlight the importance of lipidated apoE as well as the APOE-lipidation targeted therapeutic approaches that have th …
Lipids and extracellular materials.
Dowhan W. Dowhan W. Annu Rev Biochem. 2014;83:45-9. doi: 10.1146/annurev-biochem-010314-112017. Epub 2014 Mar 3. Annu Rev Biochem. 2014. PMID: 24606141
This article introduces the Lipids and Extracellular Materials theme of the Annual Review of Biochemistry, Volume 83....
This article introduces the Lipids and Extracellular Materials theme of the Annual Review of Biochemistry, Volume 83....
Vaccine development targeting lipopolysaccharide structure modification.
Zhao Y, Arce-Gorvel V, Conde-Álvarez R, Moriyon I, Gorvel JP. Zhao Y, et al. Microbes Infect. 2018 Oct-Nov;20(9-10):455-460. doi: 10.1016/j.micinf.2017.11.006. Epub 2017 Dec 9. Microbes Infect. 2018. PMID: 29233768 Free article. Review.
Vaccines are one of the most important methods for preventing infectious disease. Structural modification of lipopolysaccharide (LPS) provides a strategy for the development of live attenuated vaccines, either by altering the immunogenicity or by attenuating virulence of t …
Vaccines are one of the most important methods for preventing infectious disease. Structural modification of lipopolysaccharide (LPS) …
The atypical lipopolysaccharide of Francisella.
Okan NA, Kasper DL. Okan NA, et al. Carbohydr Res. 2013 Aug 30;378:79-83. doi: 10.1016/j.carres.2013.06.015. Epub 2013 Jul 2. Carbohydr Res. 2013. PMID: 23916469 Free PMC article. Review.
Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-negative bacteria. Genetic and structural characterizations of Francisella LPS have revealed substantial differences when compared …
Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-ne
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