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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 2
1968 2
1985 1
1986 1
1987 5
1988 5
1989 15
1990 57
1991 88
1992 119
1993 135
1994 127
1995 163
1996 136
1997 188
1998 195
1999 224
2000 236
2001 292
2002 461
2003 501
2004 686
2005 807
2006 1016
2007 1167
2008 1258
2009 1358
2010 1421
2011 1511
2012 1525
2013 1643
2014 1500
2015 1351
2016 1274
2017 1221
2018 1242
2019 503
2020 4
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19,708 results
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Page 1
Insulin resistance: definition and consequences.
Lebovitz HE. Exp Clin Endocrinol Diabetes 2001 - Review. PMID 11460565
--Several mechanisms have been proposed as possible causes underlying the development of insulin resistance and the insulin resistance syndrome. ...Insulin resistance occurs as part of a cluster of cardiovascular-metabolic abnormalities commonly referred to as "The Insulin Resistance Syndrome" or "The Metabolic Syndrome". ...
--Several mechanisms have been proposed as possible causes underlying the development of insulin resistance and the insulin
[Molecular Mechanisms of Insulin Resistance: An Update].
Gutiérrez-Rodelo C, et al. Gac Med Mex 2017 - Review. PMID 28474708 Spanish. Free article.
If these mechanisms are altered, this can lead to a condition known as insulin resistance, which is the consequence of a deficient insulin signaling caused by mutations or post-translational modifications of the receptor or effector molecules located downstream. ...In recent years, it has been found that conditions such as inflammation, endoplasmic reticulum stress, and mitochondrial dysfunction promote insulin resistance. ...
If these mechanisms are altered, this can lead to a condition known as insulin resistance, which is the consequence of a defic …
Metabolic syndrome
Samson SL and Garber AJ. Endocrinol Metab Clin North Am 2014 - Review. PMID 24582089
Obesity and insulin resistance are believed to be at the core of most cases of metabolic syndrome, although further research is required to truly understand the pathophysiology behind the syndrome and the gene-environment interactions that increase susceptibility. The mainstay of treatment remains lifestyle changes with exercise and diet to induce weight loss and pharmacologic intervention to treat atherogenic dyslipidemia, hypertension, and hyperglycemia....
Obesity and insulin resistance are believed to be at the core of most cases of metabolic syndrome, although further researc
Insulin Resistance, Prediabetes, Metabolic Syndrome: What Should Every Pediatrician Know?
Ighbariya A and Weiss R. J Clin Res Pediatr Endocrinol 2017 - Review. PMID 29280741 Free PMC article.
The syndrome is also known as "Insulin Resistance syndrome" as a substantial part of the pathophysiology is driven by resistance to the metabolic effects of insulin. The major cause of insulin resistance in childhood is a typical lipid partitioning pattern characterized by increased deposition of lipids within insulin responsive tissues, such as the liver and skeletal muscle and within the viscera. ...
The syndrome is also known as "Insulin Resistance syndrome" as a substantial part of the pathophysiology is driven by resis
Insulin Resistance in Gastroesophageal Reflux Disease.
Budiyani L, et al. Acta Med Indones 2018 - Review. PMID 30631000 Free article.
Insulin resistance is the disturbance of glucose regulation characterized by higher insulin level. In clinical context, insulin resistance can manifest as abnormalities that are related with cardiovascular event risk, known as metabolic syndrome. Several studies had reported that insulin resistance was associated with erosive esophagitis in patients with gastroesophageal reflux disease (GERD)....
Insulin resistance is the disturbance of glucose regulation characterized by higher insulin level. In clinical c
Cellular Stresses and Stress Responses in the Pathogenesis of Insulin Resistance.
Onyango AN. Oxid Med Cell Longev 2018 - Review. PMID 30116482 Free PMC article.
Insulin resistance (IR), a key component of the metabolic syndrome, precedes the development of diabetes, cardiovascular disease, and Alzheimer's disease. ...Thus, insulin resistance may be prevented or attenuated by multiple approaches targeting the different cellular stresses and stress responses....
Insulin resistance (IR), a key component of the metabolic syndrome, precedes the development of diabetes, cardiovascular disea
Insulin resistance.
Krentz AJ. BMJ 1996 - Review. PMID 8956710 Free PMC article.
Indirect insulin resistance detection: Current clinical trends and laboratory limitations.
Placzkowska S, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 - Review. PMID 31165793 Free article.
Excess adipose tissue impairs the action of insulin, leading to insulin resistance (IR). Tissue IR is a major factor in relation to cardiovascular disease, metabolic syndrome and diabetes. Thus, it is important to recognize at the pre-disease stage with the possibility of therapeutic intervention. IR is assessed using indicators of epidemiological significance, most often calculated from fasting and postprandial glucose and insulin values, so-called indirect indicators of insulin resistance. ...
Excess adipose tissue impairs the action of insulin, leading to insulin resistance (IR). Tissue IR is a major factor in …
The Effects of Insulin Resistance on Individual Tissues: An Application of a Mathematical Model of Metabolism in Humans.
Pearson T, et al. Bull Math Biol 2016. PMID 27306890 Free PMC article.
Insulin-resistant states such as type 2 diabetes and obesity are characterised by reduced efficiency of these mechanisms. Exactly how these insulin-resistant states develop, for example whether there is an order in which tissues become insulin resistant, is an active area of research with the hope of gaining a better overall understanding of insulin resistance. ...Second, insulin resistance causes a fatty liver, and the insulin resistance of tissues other than the liver can cause fat to accumulate in the liver. ...
Insulin-resistant states such as type 2 diabetes and obesity are characterised by reduced efficiency of these mechanism
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