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2011 8
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2018 76
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Page 1
Furoxan derivatives with antimalarial activity that disrupt P. falciparum endoplasmic reticulum calcium homeostasis.
da Costa Clementino L, Bartlett PJ, Fernandes GFS, Honorio RI, Legac J, Dos Santos JL, Rosenthal PJ, Garcia CRS, Thomas AP, Graminha MAS. da Costa Clementino L, et al. Int J Parasitol Drugs Drug Resist. 2026 May 14;31:100648. doi: 10.1016/j.ijpddr.2026.100648. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2026. PMID: 42142428 Free PMC article.
Unpacking boxes: identification of novel inhibitors of malaria parasite invasion.
Barnes CB, Schneider MP, Ventura OD, Razook Z, McCann K, Boulet C, Literski AH, Barry AE, Sleebs BE, Crabb BS, Gilson PR, Bullen HE. Barnes CB, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr 27;31:100647. doi: 10.1016/j.ijpddr.2026.100647. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2026. PMID: 42085784 Free PMC article.
Pharmacology and toxicology of veterinary isoxazolines: a review.
Markowska-Buńka P, Rasiński B, Ziółkowski H. Markowska-Buńka P, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr 16;31:100645. doi: 10.1016/j.ijpddr.2026.100645. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2026. PMID: 42013589 Free PMC article. Review.
The detection of three independent benzimidazole resistance mutations in a single Ancylostoma caninum population from a Golden Retriever breeding kennel in Sao Paulo, Brazil.
Dini M, Chen R, Redman E, Leutenegger CM, Tereski J, Loo S, Savard C, Jimenez Castro PD, Miyashiro SI, Gilleard J. Dini M, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr 14;31:100643. doi: 10.1016/j.ijpddr.2026.100643. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2026. PMID: 42019188 Free PMC article.
Terpenic compounds possess anthelmintic and immunomodulatory properties with potential for controlling equine cyathostomin infections.
Malsa J, Chereau A, Guégnard F, Serreau D, Gesbert A, Reigner F, Chamoin L, Guillot J, Vernudachi A, Mach N, Fleurance G, Lacroix-Lamandé S, Williams AR, Sallé G. Malsa J, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr 12;31:100642. doi: 10.1016/j.ijpddr.2026.100642. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2026. PMID: 42001742 Free PMC article.
TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants.
Rohr CM, Park SK, Aguiar-Martins K, Anderson TJC, Berger DJ, Berriman M, Buddenborg SK, Bustinduy AL, Chevalier FD, Cotton JA, Crellen T, Doyle SR, Emery AM, Kincaid Smith J, Kinung'hi S, Lamberton PHL, Le Clec'h W, Ndombi E, Pennance T, Rowel C, Summers SS, Tushabe JV, Walker M, Webster BL, Webster JP, Wilson S, Marchant JS. Rohr CM, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr;30:100639. doi: 10.1016/j.ijpddr.2026.100639. Epub 2026 Mar 18. Int J Parasitol Drugs Drug Resist. 2026. PMID: 41865684 Free PMC article.
Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4.
Lukáč M, Pisárčik M, Garajová M, Walochnik J, Ošustová D, Vatrtová E, Bondar I, Devínsky F, Mrva M. Lukáč M, et al. Int J Parasitol Drugs Drug Resist. 2026 Apr;30:100636. doi: 10.1016/j.ijpddr.2026.100636. Epub 2026 Feb 4. Int J Parasitol Drugs Drug Resist. 2026. PMID: 41655451 Free PMC article.
CRISPR-Cas13b mediated gene knockdowns in Leishmania infantum.
Queffeulou M, Fakhfakh R, Fani F, Dos Santos A, Reis Ferreira G, Bigot S, Godin C, Leprohon P, Papadopoulou B, Ouellette M. Queffeulou M, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100629. doi: 10.1016/j.ijpddr.2025.100629. Epub 2025 Dec 5. Int J Parasitol Drugs Drug Resist. 2025. PMID: 41365143 Free PMC article.
Evaluating the efficacy of different praziquantel treatment regimens using egg and circulating anodic antigen (CAA) detection methods in a Schistosoma mansoni endemic area in northeastern Brazil.
de Freitas Galvão RL, Hoekstra PT, Corstjens PLAM, Pinheiro MCC, da Silva AM, Barbosa L, César Souza Sá SL, van Dam GJ, de Moraes Bezerra FS. de Freitas Galvão RL, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100628. doi: 10.1016/j.ijpddr.2025.100628. Epub 2025 Nov 26. Int J Parasitol Drugs Drug Resist. 2025. PMID: 41337908 Free PMC article. Clinical Trial.
Recent advances in intestinal helminth parasites of horses in the Asia-Pacific region: Current trends, challenges and future directions.
Abbas G, Nielsen MK, E-Hage C, Ghafar A, Beveridge I, Bauquier J, Beasley A, Wilkes EJA, Carrigan P, Cudmore L, Jacobson C, Hughes KJ, Jabbar A. Abbas G, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100622. doi: 10.1016/j.ijpddr.2025.100622. Epub 2025 Oct 17. Int J Parasitol Drugs Drug Resist. 2025. PMID: 41135277 Free PMC article. Review.
Trialling the SmartWorm® application in New Zealand sheep farms.
Brosnahan CL, Warburton D, Cotter N, Tanner JC, Greer AW. Brosnahan CL, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100616. doi: 10.1016/j.ijpddr.2025.100616. Epub 2025 Sep 24. Int J Parasitol Drugs Drug Resist. 2025. PMID: 41014694 Free PMC article.
In vitro antiplasmodial activities of extract and fractions from Lepidobotrys staudtii against sensitive and resistant blood-stage parasites of Plasmodium falciparum.
Magoudjou Pekam JN, Efange NM, Mishro L, Keumoe R, Ndjakou BL, Ayong L, Njayou FN, Moundipa PF, Rajendran V. Magoudjou Pekam JN, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100610. doi: 10.1016/j.ijpddr.2025.100610. Epub 2025 Aug 25. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40925110 Free PMC article.
Faecal egg count reduction test, deep amplicon sequencing of isotype-1 β-tubulin gene and in ovo larval development assay reveal susceptibility to benzimidazoles of porcine nematodes Oesophagostomum spp. and Ascaris suum in outdoor-reared pigs in Germany.
Fischer HR, Krücken J, Fiedler S, Thamsborg SM, Nienhoff H, Steuber S, Daher R, von Samson-Himmelstjerna G. Fischer HR, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100612. doi: 10.1016/j.ijpddr.2025.100612. Epub 2025 Aug 28. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40902421 Free PMC article.
A novel intron variant is associated with emerging pfdhps mutant haplotypes in West and Central African Plasmodium falciparum.
Hocke EF, Hansson H, Chopo-Pizarro A, Adegbola AJ, Bolaji O, Ngwa Niba PT, Ali IM, Nji A, Mbacham W, Baraka V, Kulaya NB, Kahunu GM, Mavoko HM, Nkoli PM, Sompwe EM, Mbongi D, Mitashi P, Bédia VA, Gnagne PA, Konaté A, Yavo W, Menan H, Beshir K, Mousa A, Sutherland CJ, Alifrangis M, Roper C. Hocke EF, et al. Int J Parasitol Drugs Drug Resist. 2025 Dec;29:100611. doi: 10.1016/j.ijpddr.2025.100611. Epub 2025 Aug 26. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40882319 Free PMC article.
Mechanistic, in-silico and in vitro studies with nitrofurans reveal potent leishmanicidal activity and inhibition of trypanothione reductase.
Andrés-Rodríguez J, González-Montero MC, García-Fernández N, Galano-Frutos JJ, Rosa MC, Ferreira P, Pérez-Pertejo MY, Reguera RM, Balaña-Fouce R, García-Estrada C. Andrés-Rodríguez J, et al. Int J Parasitol Drugs Drug Resist. 2025 Aug;28:100605. doi: 10.1016/j.ijpddr.2025.100605. Epub 2025 Jul 31. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40768926 Free PMC article.
Global equine parasite control guidelines: Consensus or confusion?
Nielsen MK, Pyatt A, Perrett J, Tydén E, van Doorn D, Pihl TH, Schmidt JS, von Samson-Himmelstjerna G, Beasley A, Abbas G, Jabbar A. Nielsen MK, et al. Int J Parasitol Drugs Drug Resist. 2025 Aug;28:100600. doi: 10.1016/j.ijpddr.2025.100600. Epub 2025 Jun 3. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40472642 Free PMC article. Review.
Combination astragaloside IV and artesunate preserves blood-brain barrier integrity by modulating astrocytes and tight junction proteins in Plasmodium yoelii infection.
Sanguanwong P, Khowawisetsut L, Kwathai L, Varinthra P, Turbpaiboon C, Uawithya P, Sobhon P, Liu IY, Chompoopong S. Sanguanwong P, et al. Int J Parasitol Drugs Drug Resist. 2025 Aug;28:100598. doi: 10.1016/j.ijpddr.2025.100598. Epub 2025 May 28. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40466596 Free PMC article.
New derivatives of benzhydroxamic acid with nematocidal activity against Haemonchus contortus and Caenorhabditis elegans.
Krátký J, Zajíčková M, Taki AC, Michel O, Matoušková P, Vokřál I, Štěrbová K, Vosála O, Lungerich B, Kurz T, Gasser RB, Harant K, Skálová L. Krátký J, et al. Int J Parasitol Drugs Drug Resist. 2025 Aug;28:100599. doi: 10.1016/j.ijpddr.2025.100599. Epub 2025 May 20. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40413827 Free PMC article.
Resistance to apicoplast translational inhibitors in Plasmodium.
Home JL, McFadden GI, Goodman CD. Home JL, et al. Int J Parasitol Drugs Drug Resist. 2025 Aug;28:100597. doi: 10.1016/j.ijpddr.2025.100597. Epub 2025 May 10. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40381412 Free PMC article. Review.
A graphical user interface for wrmXpress 2.0 streamlines helminth phenotypic screening.
Caterer Z, Horejsi RV, Weber C, Mathisen B, Nelson CN, Bagatta M, Coughlin I, Wettstein M, Kulshrestha A, Lee HSB, Nunn LR, Zamanian M, Wheeler NJ. Caterer Z, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100588. doi: 10.1016/j.ijpddr.2025.100588. Epub 2025 Mar 20. Int J Parasitol Drugs Drug Resist. 2025. PMID: 40127511 Free PMC article.
Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States.
Jimenez Castro PD, Willcox JL, Rochani H, Richmond HL, Martinez HE, Lozoya CE, Savard C, Leutenegger CM. Jimenez Castro PD, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100584. doi: 10.1016/j.ijpddr.2025.100584. Epub 2025 Jan 31. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39919355 Free PMC article.
Combining the zebrafish embryo developmental toxicity assay (ZEDTA) with hemoglobin staining to accelerate the research of novel antimalarial drugs for pregnant women.
Borrallo-Lopez L, Guzman L, Romero NG, Sampietro A, Mallo-Abreu A, Guardia-Escote L, Teixidó E, Flick B, Fernàndez-Busquets X, Muñoz-Torrero D, Barenys M. Borrallo-Lopez L, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100582. doi: 10.1016/j.ijpddr.2025.100582. Epub 2025 Jan 22. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39889312 Free PMC article.
Selective activity of Tabebuia avellanedae against Giardia duodenalis infecting organoid-derived human gastrointestinal epithelia.
Rigamonti G, Veronesi F, Chiaradia E, Gosten-Heinrich P, Müller A, Brustenga L, de Angelis S, Tognoloni A, De Santo R, Klotz C, Lalle M. Rigamonti G, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100583. doi: 10.1016/j.ijpddr.2025.100583. Epub 2025 Jan 22. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39864282 Free PMC article.
Investigation of the threonine metabolism of Echinococcus multilocularis: The threonine dehydrogenase as a potential drug target in alveolar echinococcosis.
Kaethner M, Zumstein P, Müller J, Preza M, Grossenbacher P, Bartetzko A, Vetter L, Lochner M, Schürch S, Regnault C, Ramírez DV, Lundström-Stadelmann B. Kaethner M, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100581. doi: 10.1016/j.ijpddr.2025.100581. Epub 2025 Jan 18. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39847910 Free PMC article.
Biotransformation of anthelmintics in nematodes in relation to drug resistance.
Vosála O, Krátký J, Matoušková P, Rychlá N, Štěrbová K, Raisová Stuchlíková L, Vokřál I, Skálová L. Vosála O, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100579. doi: 10.1016/j.ijpddr.2025.100579. Epub 2025 Jan 7. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39827513 Free PMC article. Review.
Licochalcone a: A promising antiparasitic drug against giardiasis.
Zhang Y, Zhao W, Du H, Dhakal P, Chen X, Wu L, Li X, Wang R, Zhang L, Zhang S, Li J. Zhang Y, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100573. doi: 10.1016/j.ijpddr.2024.100573. Epub 2024 Dec 12. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39693890 Free PMC article.
Efficacy of fenbendazole against gastrointestinal nematodes in naturally infected goats in Maputo Province, Mozambique using in vivo, in vitro and molecular assessment.
Guinda EFX, Afonso SMS, Fiedler S, Morgan ER, Ramünke S, Borchert M, Atanásio A, Capece BPS, Krücken J, von Samson-Himmelstjerna G. Guinda EFX, et al. Int J Parasitol Drugs Drug Resist. 2025 Apr;27:100572. doi: 10.1016/j.ijpddr.2024.100572. Epub 2024 Dec 6. Int J Parasitol Drugs Drug Resist. 2025. PMID: 39671856 Free PMC article.
Deep-amplicon sequencing of the complete beta-tubulin gene in Trichuris trichiura before and after albendazole treatment.
Gandasegui J, Grau-Pujol B, Novela V, Muchisse O, Cambra-Pellejà M, Cossa A, Jamine JC, Sacoor C, Brienen EAT, Catala-Moll F, van Lieshout L, Martínez-Valladares M, Paredes R, Muñoz J, Doyle SR. Gandasegui J, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100570. doi: 10.1016/j.ijpddr.2024.100570. Epub 2024 Nov 12. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39546832 Free PMC article.
Profile of molecular markers of Sulfadoxine-Pyrimethamine-resistant Plasmodium falciparum in individuals living in southern area of Brazzaville, Republic of Congo.
Djontu JC, Baina MT, Mbama Ntabi JD, Lissom A, Umuhoza DM, Assioro Doulamo NV, Vouvoungui CJ, Boumpoutou RK, Mouanga AM, Nguimbi E, Ntoumi F. Djontu JC, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100569. doi: 10.1016/j.ijpddr.2024.100569. Epub 2024 Oct 26. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39488015 Free PMC article.
In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast.
Ouji M, Reyser T, Yamaryo-Botté Y, Nguyen M, Rengel D, Dutreuil A, Marcellin M, Burlet-Schiltz O, Augereau JM, Riscoe MK, Paloque L, Botté C, Benoit-Vical F. Ouji M, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100565. doi: 10.1016/j.ijpddr.2024.100565. Epub 2024 Sep 19. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39332236 Free PMC article.
Corrigendum to "Efficacy of flukicides against Fasciola hepatica and first report of triclabendazole resistance on German sheep farms" [Int. J. Parasitol. Drugs Drug Resist. 23 (2023) 94-105].
Kahl A, von Samson-Himmelstjerna G, Helm C, Hodgkinson J, Williams D, Weiher W, Terhalle W, Steuber S, Ganter M, Krücken J. Kahl A, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100562. doi: 10.1016/j.ijpddr.2024.100562. Epub 2024 Aug 13. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39168772 Free PMC article. No abstract available.
A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei.
Call DH, Adjei JA, Pilgrim R, Jeong JW, Willis EV, Zegarra RA, Tapia NL, Osterhaus M, Vance JA, Voyton CM, Call JA, Pizarro SS, Morris JC, Christensen KA. Call DH, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100557. doi: 10.1016/j.ijpddr.2024.100557. Epub 2024 Aug 8. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39163740 Free PMC article.
Inhibition of Giardia duodenalis by isocryptolepine -triazole adducts and derivatives.
Popruk S, Tummatorn J, Sreesai S, Ampawong S, Thiangtrongjit T, Tipthara P, Tarning J, Thongsornkleeb C, Ruchirawat S, Reamtong O. Popruk S, et al. Int J Parasitol Drugs Drug Resist. 2024 Dec;26:100561. doi: 10.1016/j.ijpddr.2024.100561. Epub 2024 Aug 13. Int J Parasitol Drugs Drug Resist. 2024. PMID: 39151240 Free PMC article.
Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice.
de Sousa MCF, Imhof D, Hänggeli KPA, Choi R, Hulverson MA, Arnold SLM, Van Voorhis WC, Fan E, Roberto SS, Ortega-Mora LM, Hemphill A. de Sousa MCF, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100553. doi: 10.1016/j.ijpddr.2024.100553. Epub 2024 Jun 19. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38917582 Free PMC article.
Plasmodium RNA triphosphatase validation as antimalarial target.
Moliner-Cubel S, Bahamontes-Rosa N, Rodriguez-Alejandre A, Nassau PM, Argyrou A, Bhardwaja A, Buxton RC, Calvo-Vicente D, Mouzon B, McDowell W, Mendoza-Losana A, Gomez-Lorenzo MG. Moliner-Cubel S, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100537. doi: 10.1016/j.ijpddr.2024.100537. Epub 2024 Apr 26. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38810336 Free PMC article.
Acaricide resistance status of livestock ticks from East and West Africa and in vivo efficacy of acaricides to control them.
Evans A, Madder M, Fourie J, Halos L, Kumsa B, Kimbita E, Byaruhanga J, Mwiine FN, Muhanguzi D, Adehan SB, Toure A, Nzalawahe J, Aboagye-Antwi F, Ogo NI, Meyer L, Jongejan F, Cheikhi IB, Fisher M, Holdsworth P. Evans A, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100541. doi: 10.1016/j.ijpddr.2024.100541. Epub 2024 May 6. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38761529 Free PMC article.
Faecal egg count reduction tests and nemabiome analysis reveal high frequency of multi-resistant parasites on sheep farms in north-east Germany involving multiple strongyle parasite species.
Krücken J, Ehnert P, Fiedler S, Horn F, Helm CS, Ramünke S, Bartmann T, Kahl A, Neubert A, Weiher W, Daher R, Terhalle W, Klabunde-Negatsch A, Steuber S, von Samson-Himmelstjerna G. Krücken J, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100547. doi: 10.1016/j.ijpddr.2024.100547. Epub 2024 May 5. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38733882 Free PMC article.
In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii.
Boubaker G, Bernal A, Vigneswaran A, Imhof D, de Sousa MCF, Hänggeli KPA, Haudenschild N, Furrer J, Păunescu E, Desiatkina O, Hemphill A. Boubaker G, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100544. doi: 10.1016/j.ijpddr.2024.100544. Epub 2024 Apr 27. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38703737 Free PMC article.
Treating cryptosporidiosis: A review on drug discovery strategies.
Lenière AC, Vlandas A, Follet J. Lenière AC, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100542. doi: 10.1016/j.ijpddr.2024.100542. Epub 2024 Apr 20. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38669849 Free PMC article. Review.
Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides.
Redway A, Spry C, Brown A, Wiedemann U, Fathoni I, Garnie LF, Qiu D, Egan TJ, Lehane AM, Jackson Y, Saliba KJ, Downer-Riley N. Redway A, et al. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100536. doi: 10.1016/j.ijpddr.2024.100536. Epub 2024 Apr 3. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38663046 Free PMC article.
Acrylonitrile derivatives: In vitro activity and mechanism of cell death induction against Trypanosoma cruzi and Leishmania amazonensis.
Bethencourt-Estrella CJ, Delgado-Hernández S, López-Arencibia A, San Nicolás-Hernández D, Salazar-Villatoro L, Omaña-Molina M, Tejedor D, García-Tellado F, Lorenzo-Morales J, Piñero JE. Bethencourt-Estrella CJ, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100531. doi: 10.1016/j.ijpddr.2024.100531. Epub 2024 Mar 6. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38484645 Free PMC article.
Revisiting anthelmintic resistance in sheep flocks from São Paulo State, Brazil.
Bassetto CC, Albuquerque ACA, Lins JGG, Marinho-Silva NM, Chocobar MLE, Bello HJS, Mena MO, Niciura SCM, Amarante AFT, Chagas ACS. Bassetto CC, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100527. doi: 10.1016/j.ijpddr.2024.100527. Epub 2024 Feb 28. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38447333 Free PMC article.
Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonensis.
Peixoto JF, Gonçalves-Oliveira LF, Souza-Silva F, de Castro Côrtes LM, Finkelstein LC, Dias-Lopes G, Patricio BFC, Lima CGS, Rocha HVA, da Silva FC, Ferreira VF, Pereira BAS, Alves CR. Peixoto JF, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100525. doi: 10.1016/j.ijpddr.2024.100525. Epub 2024 Feb 9. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38359731 Free PMC article.
Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Chang BCH, Wells TNC, Häberli C, Keiser J, Jabbar A, Sleebs BE, Gasser RB. Shanley HT, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100522. doi: 10.1016/j.ijpddr.2024.100522. Epub 2024 Jan 23. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38295619 Free PMC article.
Benzimidazole F167Y polymorphism in the canine hookworm, Ancylostoma caninum: Widespread geographic, seasonal, age, and breed distribution in United States and Canada dogs.
Leutenegger CM, Evason MD, Willcox JL, Rochani H, Richmond HL, Meeks C, Lozoya CE, Tereski J, Loo S, Mitchell K, Andrews J, Savard C. Leutenegger CM, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100520. doi: 10.1016/j.ijpddr.2024.100520. Epub 2024 Jan 12. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38237210 Free PMC article.
Phenotypic and genotypic characterization of acaricide resistance in Rhipicephalus microplus field isolates from South Africa and Brazil.
Heylen DJA, Labuschagne M, Meiring C, van der Mescht L, Klafke G, Costa Junior LM, Strydom T, Wentzel J, Shacklock C, Halos L, Maree F, Fourie J, Madder M, Evans A. Heylen DJA, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100519. doi: 10.1016/j.ijpddr.2023.100519. Epub 2023 Dec 27. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38168594 Free PMC article.
A national survey of anthelmintic resistance in ascarid and strongylid nematodes in Australian Thoroughbred horses.
Abbas G, Ghafar A, McConnell E, Beasley A, Bauquier J, Wilkes EJA, El-Hage C, Carrigan P, Cudmore L, Hurley J, Gauci CG, Beveridge I, Ling E, Jacobson C, Stevenson MA, Nielsen MK, Hughes KJ, Jabbar A. Abbas G, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100517. doi: 10.1016/j.ijpddr.2023.11.006. Epub 2023 Nov 29. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38064906 Free PMC article.
Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites.
Deligianni E, Pizzi E, Kavelaki I, Siden-Kiamos I, Sapienza FU, Fioravanti R, Garzoli S, Pace T, Ponzi M, Ragno R, Currà C. Deligianni E, et al. Int J Parasitol Drugs Drug Resist. 2023 Dec;23:87-93. doi: 10.1016/j.ijpddr.2023.11.002. Epub 2023 Nov 21. Int J Parasitol Drugs Drug Resist. 2023. PMID: 38000094 Free PMC article.
Ascaridia galli - An old problem that requires new solutions.
Höglund J, Daş G, Tarbiat B, Geldhof P, Jansson DS, Gauly M. Höglund J, et al. Int J Parasitol Drugs Drug Resist. 2023 Dec;23:1-9. doi: 10.1016/j.ijpddr.2023.07.003. Epub 2023 Jul 24. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37516026 Free PMC article. Review.
Multiple anthelmintic drug resistant Ancylostoma caninum in foxhounds.
Balk JD, Mitchell ND, Hughes J, Soto Nauto P, Rossi J, Ramirez-Barrios R. Balk JD, et al. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:102-106. doi: 10.1016/j.ijpddr.2023.07.001. Epub 2023 Jul 20. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37481894 Free PMC article.
In vitro activity and mechanism of cell death induction of cyanomethyl vinyl ethers derivatives against Trypanosoma cruzi.
Bethencourt-Estrella CJ, Delgado-Hernández S, López-Arencibia A, San Nicolás-Hernández D, Tejedor D, García-Tellado F, Lorenzo-Morales J, Piñero JE. Bethencourt-Estrella CJ, et al. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:72-80. doi: 10.1016/j.ijpddr.2023.05.001. Epub 2023 May 31. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37311268 Free PMC article.
Identification and characterization of novel marine oxasqualenoid yucatecone against Naegleria fowleri.
Arberas-Jiménez I, Cen-Pacheco F, Chao-Pellicer J, Sifaoui I, Rizo-Liendo A, Morales EQ, Daranas AH, Díaz-Marrero AR, Piñero JE, Fernández JJ, Lorenzo-Morales J. Arberas-Jiménez I, et al. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:61-71. doi: 10.1016/j.ijpddr.2023.05.004. Epub 2023 May 29. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37270868 Free PMC article.
Integration of ITS-2 rDNA nemabiome metabarcoding with Fecal Egg Count Reduction Testing (FECRT) reveals ivermectin resistance in multiple gastrointestinal nematode species, including hypobiotic Ostertagia ostertagi, in western Canadian beef cattle.
De Seram EL, Uehlinger FD, de Queiroz C, Redman EM, Campbell JR, Nooyen D, Morisetti A, Pollock CM, Ekanayake S, Penner GB, Gilleard JS. De Seram EL, et al. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:27-35. doi: 10.1016/j.ijpddr.2023.04.002. Epub 2023 Apr 22. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37119733 Free PMC article.
Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target.
Howieson VM, Zeng J, Kloehn J, Spry C, Marchetti C, Lunghi M, Varesio E, Soper A, Coyne AG, Abell C, van Dooren GG, Saliba KJ. Howieson VM, et al. Int J Parasitol Drugs Drug Resist. 2023 Aug;22:1-8. doi: 10.1016/j.ijpddr.2023.03.003. Epub 2023 Mar 15. Int J Parasitol Drugs Drug Resist. 2023. PMID: 37004488 Free PMC article.
Investigation of the mechanism of action of mefloquine and derivatives against the parasite Echinococcus multilocularis.
Memedovski R, Preza M, Müller J, Kämpfer T, Rufener R, de Souza MVN, da Silva ET, de Andrade GF, Braga S, Uldry AC, Buchs N, Heller M, Lundström-Stadelmann B. Memedovski R, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:114-124. doi: 10.1016/j.ijpddr.2023.03.002. Epub 2023 Mar 9. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36921443 Free PMC article.
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia.
Saghaug CS, Gamlem AL, Hauge KB, Vahokoski J, Klotz C, Aebischer T, Langeland N, Hanevik K. Saghaug CS, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:51-60. doi: 10.1016/j.ijpddr.2022.12.003. Epub 2022 Dec 21. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36682328 Free PMC article.
Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase.
Hidayati AR, Melinda, Ilmi H, Sakura T, Sakaguchi M, Ohmori J, Hartuti ED, Tumewu L, Inaoka DK, Tanjung M, Yoshida E, Tokumasu F, Kita K, Mori M, Dobashi K, Nozaki T, Syafruddin D, Hafid AF, Waluyo D, Widyawaruyanti A. Hidayati AR, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:40-50. doi: 10.1016/j.ijpddr.2022.12.001. Epub 2022 Dec 8. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36565667 Free PMC article.
Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited.
Macdonald SL, Abbas G, Ghafar A, Gauci CG, Bauquier J, El-Hage C, Tennent-Brown B, Wilkes EJA, Beasley A, Jacobson C, Cudmore L, Carrigan P, Hurley J, Beveridge I, Hughes KJ, Nielsen MK, Jabbar A. Macdonald SL, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:28-39. doi: 10.1016/j.ijpddr.2022.12.002. Epub 2022 Dec 13. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36543048 Free PMC article.
Poor adherence is a major barrier to the proper treatment of cutaneous leishmaniasis: A case-control field assessment in Iran.
Bamorovat M, Sharifi I, Agha Kuchak Afshari S, Karamoozian A, Tahmouresi A, Heshmatkhah A, Salarkia E, Khosravi A, Hakimi Parizi M, Barghi M. Bamorovat M, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:21-27. doi: 10.1016/j.ijpddr.2022.11.006. Epub 2022 Dec 5. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36525935 Free PMC article.
Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation.
Müller J, Schlange C, Heller M, Uldry AC, Braga-Lagache S, Haynes RK, Hemphill A. Müller J, et al. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:1-12. doi: 10.1016/j.ijpddr.2022.11.005. Epub 2022 Dec 8. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36512904 Free PMC article.
Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues.
Cortopassi WA, Gunderson E, Annunciato Y, Silva AES, Dos Santos Ferreira A, Garcia Teles CB, Pimentel AS, Ramamoorthi R, Gazarini ML, Meneghetti MR, Guido RVC, Pereira DB, Jacobson MP, Krettli AU, Caroline C Aguiar A. Cortopassi WA, et al. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:121-128. doi: 10.1016/j.ijpddr.2022.10.003. Epub 2022 Oct 31. Int J Parasitol Drugs Drug Resist. 2022. PMID: 36375339 Free PMC article.
Anti-malarial activity of HCl salt of SKM13 (SKM13-2HCl).
Trinh TT, Yun SY, Bae GJ, Moon K, Hong H, Eum TH, Kim YA, Kim SA, Park H, Kim HS, Yeo SJ. Trinh TT, et al. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:113-120. doi: 10.1016/j.ijpddr.2022.10.006. Epub 2022 Nov 8. Int J Parasitol Drugs Drug Resist. 2022. PMID: 36375338 Free PMC article.
Sterol profiling of Leishmania parasites using a new HPLC-tandem mass spectrometry-based method and antifungal azoles as chemical probes reveals a key intermediate sterol that supports a branched ergosterol biosynthetic pathway.
Feng M, Jin Y, Yang S, Joachim AM, Ning Y, Mori-Quiroz LM, Fromm J, Perera C, Zhang K, Werbovetz KA, Wang MZ. Feng M, et al. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:27-42. doi: 10.1016/j.ijpddr.2022.07.003. Epub 2022 Aug 15. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35994895 Free PMC article.
Inhibitory effect of morin on aldolase 2 from Eimeria tenella.
Hu J, Sun M, Qi N, Abuzeid AMI, Li J, Cai H, Lv M, Lin X, Liao S, Li G. Hu J, et al. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:1-10. doi: 10.1016/j.ijpddr.2022.07.002. Epub 2022 Aug 5. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35952522 Free PMC article.
Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization.
Hawryluk N, Zhiru L, Carlow C, Gokool S, Townson S, Kreiss T, Chojnowski A, Prorok M, Siekierka J, Ehrens A, Koschel M, Lhermitte-Vallarino N, Martin C, Hoerauf A, Hernandez G, Canan S, Khetani V, Zeldis J, Specht S, Hübner MP, Scandale I. Hawryluk N, et al. Int J Parasitol Drugs Drug Resist. 2022 Aug;19:89-97. doi: 10.1016/j.ijpddr.2022.06.002. Epub 2022 Jun 23. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35834918 Free PMC article.
Insights from the use of erythropoietin in experimental Chagas disease.
de Castro Nobre AC, Pimentel CF, do Rêgo GMS, Paludo GR, Pereira Neto GB, de Castro MB, Nitz N, Hecht M, Dallago B, Hagström L. de Castro Nobre AC, et al. Int J Parasitol Drugs Drug Resist. 2022 Aug;19:65-80. doi: 10.1016/j.ijpddr.2022.05.005. Epub 2022 Jun 17. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35772309 Free PMC article.
Natural marine products as antiprotozoal agents against amitochondrial parasites.
Estrella-Parra EA, Arreola R, Álvarez-Sánchez ME, Torres-Romero JC, Rojas-Espinosa O, De la Cruz-Santiago JA, Martinez-Benitez MB, López-Camarillo C, Lara-Riegos JC, Arana-Argáez VE, Ramírez-Camacho MA. Estrella-Parra EA, et al. Int J Parasitol Drugs Drug Resist. 2022 Aug;19:40-46. doi: 10.1016/j.ijpddr.2022.05.003. Epub 2022 May 24. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35636129 Free PMC article. Review.
Nucleoside analogues for the treatment of animal trypanosomiasis.
Mabille D, Ilbeigi K, Hendrickx S, Ungogo MA, Hulpia F, Lin C, Maes L, de Koning HP, Van Calenbergh S, Caljon G. Mabille D, et al. Int J Parasitol Drugs Drug Resist. 2022 Aug;19:21-30. doi: 10.1016/j.ijpddr.2022.05.001. Epub 2022 May 6. Int J Parasitol Drugs Drug Resist. 2022. PMID: 35567803 Free PMC article.
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