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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 15
1995 35
1996 31
1997 42
1998 49
1999 50
2000 44
2001 53
2002 49
2003 50
2004 41
2005 48
2006 53
2007 41
2008 62
2009 59
2010 50
2011 48
2012 42
2013 57
2014 53
2015 35
2016 33
2017 33
2018 30
2019 36
2020 21
2021 15
2022 23
2023 8
2024 3

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1,113 results

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Page 1
AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study.
Matsuoka K, Watanabe M, Ohmori T, Nakajima K, Ishida T, Ishiguro Y, Kanke K, Kobayashi K, Hirai F, Watanabe K, Mizusawa H, Kishida S, Miura Y, Ohta A, Kajioka T, Hibi T; AJM300 Study Group. Matsuoka K, et al. Lancet Gastroenterol Hepatol. 2022 Jul;7(7):648-657. doi: 10.1016/S2468-1253(22)00022-X. Epub 2022 Mar 30. Lancet Gastroenterol Hepatol. 2022. PMID: 35366419 Clinical Trial.
Carotegrast Methyl: First Approval.
Dhillon S. Dhillon S. Drugs. 2022 Jun;82(9):1011-1016. doi: 10.1007/s40265-022-01732-0. Drugs. 2022. PMID: 35723803 Review.
LRP12 is an endogenous transmembrane inactivator of α4 integrins.
Huang M, Lu L, Lin C, Zheng Y, Pan X, Wang S, Chen S, Zhang Y, Liu C, Ge G, Zeng YA, Chen J. Huang M, et al. Cell Rep. 2023 Jun 27;42(6):112667. doi: 10.1016/j.celrep.2023.112667. Epub 2023 Jun 17. Cell Rep. 2023. PMID: 37330909 Free article.
Natalizumab.
Berger JR. Berger JR. Drugs Today (Barc). 2006 Oct;42(10):639-55. doi: 10.1358/dot.2006.42.10.1042190. Drugs Today (Barc). 2006. PMID: 17136224 Review.
Natalizumab: Perspectives from the Bench to Bedside.
Shirani A, Stüve O. Shirani A, et al. Cold Spring Harb Perspect Med. 2018 Dec 3;8(12):a029066. doi: 10.1101/cshperspect.a029066. Cold Spring Harb Perspect Med. 2018. PMID: 29500304 Free PMC article. Review.
1,113 results