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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 8
1988 65
1989 112
1990 208
1991 219
1992 261
1993 369
1994 329
1995 373
1996 339
1997 313
1998 318
1999 285
2000 291
2001 360
2002 386
2003 433
2004 505
2005 556
2006 603
2007 646
2008 598
2009 635
2010 673
2011 575
2012 333
2013 339
2014 263
2015 221
2016 130
2017 119
2018 83
2019 33
2020 1
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10,382 results
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Page 1
The interferon-alpha revival in CML.
Talpaz M, et al. Ann Hematol 2015 - Review. PMID 25814086
Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid leukemia (CML). Its pleiotropic mechanism of action in CML includes immune activation and specific targeting of CML stem cells. ...
Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid leukemia (CML). Its pleiotropic mecha
Interferon alpha receptors and STAT1 as therapy predictors of a sustained virological response in hepatitis C/B co-infection.
Asim M, et al. J Pak Med Assoc 2018. PMID 30410131 Free article.
OBJECTIVE: : To determine the expression of interferon alpha receptors 1 and 2 along with signal transducer and activator of transcription-1 in peripheral blood mononuclear cells of both hepatitis C mono-infected and hepatitis C and B co-infected patients, and to assess whether these targeted genes predict sustained virological response to interferon therapy. ...No difference in expression was measured between the two sets of groups with regard to interferon alpha receptor 2 expression (p=0.278 and p=0.590). ...
OBJECTIVE: : To determine the expression of interferon alpha receptors 1 and 2 along with signal transducer and activat …
Interferon alpha-2a treatment for refractory Behcet uveitis in Korean patients.
Lee JH, et al. BMC Ophthalmol 2018. PMID 29463220 Free PMC article.
BACKGROUND: To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. ...
BACKGROUND: To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who w …
Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo.
Verger E, et al. Blood Cancer J 2018. PMID 30287855 Free PMC article.
Recommended treatments include hydroxyurea and interferon-alpha. Several groups have reported a reduction in the JAK2 mutant allele burden in interferon-treated patients, but significance of this observation is questioned. We characterized the activity of ropeginterferon alpha-2b, a novel form of interferon-alpha recently shown to be safe and efficacious in polycythemia vera. ...
Recommended treatments include hydroxyurea and interferon-alpha. Several groups have reported a reduction in the JAK2 mutant a …
The efficacy of intravitreal interferon alpha-2b for the treatment of experimental endotoxin-induced uveitis.
Afarid M, et al. Indian J Ophthalmol 2016. PMID 27380977 Free PMC article.
PURPOSE: To study the efficacy of intravitreal interferon alpha-2b for endotoxin-induced uveitis. MATERIALS AND METHODS: A total of 36 rabbits were randomly allocated to one of the three groups: (1) received interferon plus balanced-salt solution; (2) received lipopolysaccharide (LPS) plus interferon; and (3) received LPS plus balanced-salt solution. ...CONCLUSION: Intravitreal interferon alpha-2b was effective in controlling endotoxin-induced uveitis....
PURPOSE: To study the efficacy of intravitreal interferon alpha-2b for endotoxin-induced uveitis. MATERIALS AND METHODS: A tot …
Anti-Interferon Alpha Antibodies in Patients with High-Risk BCR/ABL-Negative Myeloproliferative Neoplasms Treated with Recombinant Human Interferon-α.
Aruna and Li L. Med Sci Monit 2018. PMID 29693647 Free PMC article.
BACKGROUND The objective of this study was to characterize the incidence and impact of immunogenicity to interferon-a (IFN-α-2a, IFN-α-2b, and Peg-IFN-α-2a) over a period of 12 months in patients with BCR/ABL-negative myeloproliferative neoplasms (MPNs). ...
BACKGROUND The objective of this study was to characterize the incidence and impact of immunogenicity to interferon-a (IFN-α-2a, IFN- …
Association of Interferon Alpha Receptor 1 with sustained virological response in hepatitis C and B co-infected patients.
Asim M, et al. J Pak Med Assoc 2017. PMID 28770872 Free article.
OBJECTIVE: To determine the association of interferon alpha receptor-1 with success rate of interferon therapy in patients co-infected with hepatitis C virus and hepatitis B virus. ...The presence of high pre-treatment interferon alpha receptors 1-messenger ribonucleic acid in peripheral blood mononuclear cells was significantly associated with sustained virological response (85.7% vs. 64.7%, P = 0.031). ...
OBJECTIVE: To determine the association of interferon alpha receptor-1 with success rate of interferon therapy in patie …
Interferon Alpha-2a Therapy in Patients with Refractory Behçet Uveitis.
Hasanreisoglu M, et al. Ocul Immunol Inflamm 2017. PMID 26910383
Group 2 consisted of patients who did not respond to conventional combination therapy, and were therefore treated with IFNα2a. ...In Group 2, a significant decrease in the mean number of uveitis attacks/year per patient was observed after initiation of IFNα2a (2.4 ± 1.8 vs 1.3 ± 2.0) (p<0.05). ...
Group 2 consisted of patients who did not respond to conventional combination therapy, and were therefore treated with IFNα2a. ...In …
Interferon alpha-2a as alternative treatment for conjunctival squamous cell carcinoma.
Cruzado-Sánchez D, et al. Arch Soc Esp Oftalmol 2017. PMID 28522115
DISCUSSION: Interferon alpha-2b has been used at conjunctival level as a topical immunomodulator treatment, with complete remission of epithelial neoplasms being observed. However, there have not been any previous publications on the use of interferon alpha-2a, which differs from interferon alpha-2b in a single amino acid, for the treatment of conjunctival squamous cell carcinoma....
DISCUSSION: Interferon alpha-2b has been used at conjunctival level as a topical immunomodulator treatment, with complete remi …
Interferon Alpha-2b Eye Drops Prevent Recurrence of Pterygium After the Bare Sclera Technique: A Single-Center, Sequential, and Controlled Study.
Yin M, et al. Cornea 2019 - Clinical Trial. PMID 31299663 Free PMC article.
PURPOSE: To investigate the efficacy and safety of interferon (IFN) alpha-2b eye drops in preventing pterygium recurrence after the bare sclera technique. ...CONCLUSIONS: Administration of IFN alpha-2b eye drops after the bare sclera technique appear safe and effective in reducing the recurrence of pterygium....
PURPOSE: To investigate the efficacy and safety of interferon (IFN) alpha-2b eye drops in preventing pterygium recurrence afte …
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