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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 6
1988 36
1989 79
1990 150
1991 252
1992 358
1993 473
1994 484
1995 596
1996 561
1997 483
1998 519
1999 477
2000 517
2001 514
2002 505
2003 570
2004 579
2005 588
2006 568
2007 622
2008 532
2009 575
2010 585
2011 645
2012 583
2013 594
2014 559
2015 471
2016 312
2017 254
2018 172
2019 64
2020 1
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13,465 results
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Page 1
Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases.
Stewart TA. Cytokine Growth Factor Rev 2003 - Review. PMID 12651225
Interferon alpha (IFN-alpha) is induced by viruses (linked by epidemiological studies to autoimmune diseases), has significant direct effects on both epithelial cells and the immune system, and then can be further induced by the autoantibodies and apoptotic cells generated by the actions of IFN-alpha. ...This review will evaluate the rationale for, possible approaches to, and safety concerns associated with, targeting interferon alpha (IFN-alpha) as a therapeutic strategy for the treatment of autoimmune diseases. ...
Interferon alpha (IFN-alpha) is induced by viruses (linked by epidemiological studies to autoimmune diseases), has significant direct
Immunomodulation and therapeutic effects of the oral use of interferon-alpha: mechanism of action.
Tompkins WA. J Interferon Cytokine Res 1999 - Review. PMID 10476925
It is now well accepted that type 1 interferons (IFNs), IFN-alpha and IFN-beta, in addition to being molecules with powerful antiviral activity, play a critical role in modulating immune responses to foreign and self-antigens. ...
It is now well accepted that type 1 interferons (IFNs), IFN-alpha and IFN-beta, in addition to being molecules with powerful antivira …
[THERAPEUTIC POTENTIAL OF ALPHA-INTERFERON PREPARATIONS DUR- ING SOCIALLY-SIGNIFICANT HUMAN DISEASES OF VIRAL ETIOLOGY].
Ospelnikova TP, et al. Zh Mikrobiol Epidemiol Immunobiol 2016 - Review. PMID 30695356 Russian.
Interferons (IFN) belong to key cytokines of innate and adaptive immune response and play an important role in anti-viral and anti-tumor protection. ...
Interferons (IFN) belong to key cytokines of innate and adaptive immune response and play an important role in anti-viral and anti-tu
Long-term therapeutic efficacy and toxicity of recombinant interferon-alpha 2a in polycythaemia vera.
Foa P, et al. Eur J Haematol 1998. PMID 9654155
We report on long-term therapeutic efficacy and toxicity of recombinant interferon-alpha 2a (rIFN-alpha) in a series of 38 patients with polycythaemia vera (PV). ...
We report on long-term therapeutic efficacy and toxicity of recombinant interferon-alpha 2a (rIFN-alpha) in a series of 38 patients w …
Use of alpha-interferon in the treatment of chronic delta hepatitis.
Hadziyannis SJ. J Hepatol 1991 - Clinical Trial. PMID 1835731
Treatment with alpha-interferon (alpha-IFN) can inhibit HDV replication and improve serum chemistries in a number of patients. ...
Treatment with alpha-interferon (alpha-IFN) can inhibit HDV replication and improve serum chemistries in a number of patients. ...
Interferon-alpha as an immunotherapeutic protein.
Brassard DL, et al. J Leukoc Biol 2002 - Review. PMID 11927642
Interferon-alpha (IFN-alpha) has proven to be a clinically effective antiviral and antineoplastic therapeutic drug for more than 16 years. ...
Interferon-alpha (IFN-alpha) has proven to be a clinically effective antiviral and antineoplastic therapeutic drug for more than 16 y
UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia.
Allan NC, et al. Lancet 1995 - Clinical Trial. PMID 7760609
Interferon-alpha may be better than cytotoxic drugs in the long-term management of patients with chronic myeloid leukaemia (CML) in chronic phase. To test this possibility 587 patients with CML in chronic phase were randomly allocated to receive lymphoblastoid cell-line interferon-alpha n1 (IFN-alpha, n = 293) or chemotherapy with busulphan or hydroxyurea (no IFN-alpha, n = 294) as maintenance after initial induction treatment with cytotoxic drugs. ...
Interferon-alpha may be better than cytotoxic drugs in the long-term management of patients with chronic myeloid leukaemia (CML) in c
Pegylated interferon for treating severe recurrent respiratory papillomatosis in a child: case report.
Maunsell R and Bellomo-Brandão MA. Sao Paulo Med J 2018. PMID 28977096 Free article.
Adjuvant therapies are indicated in these cases and interferon is one of the options. Pegylated interferon is more effective than conventional alpha interferon and, given its reported results in relation to treating hepatitis C over the past decade, we hypothesized that this might be more effective than conventional interferon also for treating respiratory papillomatosis. ...CONCLUSION: Pegylated interferon may be a good option for diminishing the need for surgical intervention in severe cases of recurrent respiratory papillomatosis....
Adjuvant therapies are indicated in these cases and interferon is one of the options. Pegylated interferon is more effective t …
Interferon alpha for chronic hepatitis D.
Abbas Z, et al. Cochrane Database Syst Rev 2011 - Review. PMID 22161394 Free PMC article.
Five trials compared interferon alpha with no treatment in the control group. One of these trials had two treatment arms with a higher dose and lower dose of interferon alpha and a no-treatment control group. ...The sixth trial compared only a higher dose of interferon alpha with a lower dose.Meta-analysis of five trials comparing interferon alpha with no-treatment control group included 169 participants. ...
Five trials compared interferon alpha with no treatment in the control group. One of these trials had two treatment arms with a highe …
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