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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1981 6
1982 19
1983 52
1984 72
1985 84
1986 102
1987 74
1988 127
1989 118
1990 138
1991 156
1992 130
1993 158
1994 181
1995 234
1996 222
1997 208
1998 261
1999 280
2000 324
2001 313
2002 308
2003 313
2004 317
2005 351
2006 367
2007 400
2008 430
2009 451
2010 392
2011 429
2012 365
2013 315
2014 312
2015 266
2016 282
2017 236
2018 227
2019 80
2020 1
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8,491 results
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Page 1
Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis.
Doan TN, et al. PLoS One 2017. PMID 29182688 Free PMC article.
We performed the largest meta-analysis to date aiming to evaluate the performance of tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) for LTBI diagnosis in various patient populations using Bayesian latent class modelling. ...
We performed the largest meta-analysis to date aiming to evaluate the performance of tuberculin skin test (TST) and interferon-gam
Cerebral malaria: gamma-interferon redux.
Hunt NH, et al. Front Cell Infect Microbiol 2014 - Review. PMID 25177551 Free PMC article.
One factor that seems able to knit together much of this complexity is the cytokine interferon-gamma (IFN-γ). In this review we consider findings from the clinical disease, in vitro models and the murine counterpart of human cerebral malaria in order to evaluate the roles played by IFN-γ in the pathogenesis of this often fatal and debilitating condition....
One factor that seems able to knit together much of this complexity is the cytokine interferon-gamma (IFN-γ). In this review w …
One interferon gamma receptor binds one interferon gamma dimer.
Fountoulakis M, et al. J Biol Chem 1990. PMID 2147181 Free article.
We investigated the stoichiometry of the interferon gamma and interferon gamma receptor interaction, using recombinant interferon gamma and recombinant soluble interferon gamma receptor, applying chemical cross-linking and chromatographic techniques, and analyzing the resulting products in denaturing polyacrylamide gels. ...The found results suggest that the interferon gamma receptor binds interferon gamma as a dimer....
We investigated the stoichiometry of the interferon gamma and interferon gamma receptor interaction, using recom …
Interferon-γ interferes with host cell metabolism during intracellular Chlamydia trachomatis infection.
Shima K, et al. Cytokine 2018. PMID 29885991
Interferon-γ (IFN-γ) is a central mediator of host immune responses including T-cell differentiation and activation of macrophages for the control of bacterial pathogens. ...In conclusions, anti-chlamydial activity of IFN-γ goes beyond tryptophan depletion including interference with cellular energy metabolism resulting reduced progeny, but also impaired antimicrobial susceptibility of C. trachomatis....
Interferon-γ (IFN-γ) is a central mediator of host immune responses including T-cell differentiation and activation of macrophages fo
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
York AG, et al. Cell 2015. PMID 26686653 Free PMC article.
Using isotope tracer analysis, we show that type I interferon (IFN) signaling shifts the balance of these programs by decreasing synthesis and increasing import of cholesterol and long chain fatty acids. ...
Using isotope tracer analysis, we show that type I interferon (IFN) signaling shifts the balance of these programs by decreasing synt …
Importance of the loop connecting A and B helices of human interferon-gamma in recognition by interferon-gamma receptor.
Lundell D, et al. J Biol Chem 1994. PMID 8206916 Free article.
Characterization of murine-human hybrid interferon-gamma (IFN-gamma) molecules suggests that substitution of the peptide connecting the A and B helices in human IFN-gamma with the murine sequence significantly blocks the protein's binding to the human interferon-gamma receptor. ...This metal complex lacks the ability to interact with the interferon-gamma receptor. These results suggest that the A-B loop contains important structural information needed for receptor-ligand binding and hence biological activity of human interferon-gamma....
Characterization of murine-human hybrid interferon-gamma (IFN-gamma) molecules suggests that substitution of the peptid …
Interferon gamma induces cellular protein alteration and increases replication of porcine circovirus type 2 in PK-15 cells.
Mutthi P, et al. Arch Virol 2018. PMID 30039317
Interferon gamma (IFN-γ) is known to enhance PCV2 replication in vitro, and immune mediators may act as pivotal factors in triggering PCV2 infection progression toward PCVAD. ...
Interferon gamma (IFN-γ) is known to enhance PCV2 replication in vitro, and immune mediators may act as pivotal factors in tri
Interferon-gamma regulation of intestinal epithelial permeability.
Beaurepaire C, et al. J Interferon Cytokine Res 2009 - Review. PMID 19196071
Interferon-gamma is a pleiotrophic cytokine produced predominantly by natural kill cells and CD4+ T cells that under normal circumstances, and particularly during infection or inflammation, will be a component of the intestinal milieu. Use of colon-derived epithelial cell lines and, to a less extent, murine in vivo analyses, have revealed that interferon-gamma (IFN-gamma) can increase epithelial permeability as gauged by markers of paracellular permeability and bacterial transcytosis, with at least a portion of the bacteria using the transcellular permeation pathway. ...
Interferon-gamma is a pleiotrophic cytokine produced predominantly by natural kill cells and CD4+ T cells that under normal ci
Characterization of the In Vitro Chlamydia pecorum Response to Gamma Interferon.
Islam MM, et al. Infect Immun 2018. PMID 29358337 Free PMC article.
In humans and animals, a gamma interferon (IFN-γ)-mediated immune response is important for the control of intracellular bacteria. ...
In humans and animals, a gamma interferon (IFN-γ)-mediated immune response is important for the control of intracellular bacte …
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