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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1981 10
1982 36
1983 71
1984 118
1985 143
1986 187
1987 166
1988 254
1989 251
1990 297
1991 368
1992 386
1993 482
1994 506
1995 652
1996 764
1997 874
1998 964
1999 1136
2000 1306
2001 1497
2002 1510
2003 1595
2004 1671
2005 1684
2006 1701
2007 1886
2008 2033
2009 2110
2010 1940
2011 2019
2012 1919
2013 1846
2014 1647
2015 1540
2016 1364
2017 1251
2018 1042
2019 422
2020 9
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36,613 results
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Page 1
Review of the recombinant human interferon gamma as an immunotherapeutic: Impacts of production platforms and glycosylation.
Razaghi A, et al. J Biotechnol 2016 - Review. PMID 27794496
Human interferon gamma is a cytokine belonging to a diverse group of interferons which have a crucial immunological function against mycobacteria and a wide variety of viral infections. ...Recombinant human interferon gamma, as a lucrative biopharmaceutical, has been engineered in different expression systems including prokaryotic, protozoan, fungal (yeasts), plant, insect and mammalian cells. ...
Human interferon gamma is a cytokine belonging to a diverse group of interferons which have a crucial immunological function a …
Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis.
Doan TN, et al. PLoS One 2017. PMID 29182688 Free PMC article.
We performed the largest meta-analysis to date aiming to evaluate the performance of tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) for LTBI diagnosis in various patient populations using Bayesian latent class modelling. ...
We performed the largest meta-analysis to date aiming to evaluate the performance of tuberculin skin test (TST) and interferon-gam
Tributyltin stimulates synthesis of interferon gamma and tumor necrosis factor alpha in human lymphocytes.
Lawrence S, et al. J Appl Toxicol 2018. PMID 29532501 Free PMC article.
Recently, we found that exposures to TBT caused increased secretion of two important proinflammatory cytokines, tumor necrosis factor alpha (TNFα) and interferon gamma (IFNγ). ...
Recently, we found that exposures to TBT caused increased secretion of two important proinflammatory cytokines, tumor necrosis factor alpha …
Interferon-gamma, the activated macrophage, and host defense against microbial challenge.
Murray HW. Ann Intern Med 1988 - Review. PMID 3126690
In animal models, treatment with recombinant interferon-gamma is beneficial in systemic intracellular infections, and inhibition of endogenous interferon-gamma activity impairs host resistance. ...This research and the identification of patients whose T cells fail to produce interferon-gamma properly has set the stage for evaluating the role of macrophage-activating immunotherapy using interferon-gamma in various human infectious diseases....
In animal models, treatment with recombinant interferon-gamma is beneficial in systemic intracellular infections, and inhibiti …
The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor.
Pestka S, et al. Cytokine Growth Factor Rev 1997 - Review. PMID 9462485
With the purification and cloning of the interferon gamma (IFN-gamma) receptor chains the mechanism of IFN-gamma action and the resultant signal transduction events were delineated in remarkable detail. The interferon gamma (IFN-gamma) receptor complex consists of two chains: IFN-gammaR1, the ligand-binding chain, and IFN-gammaR2, the accessory chain. ...
With the purification and cloning of the interferon gamma (IFN-gamma) receptor chains the mechanism of IFN-gamma
Metabolic Regulation of Natural Killer Cell IFN-γ Production
Mah AY and Cooper MA. Crit Rev Immunol 2016 - Review. PMID 27910764 Free PMC article.
Metabolism is critical for a host of cellular functions and provides a source of intracellular energy. It has been recognized recently that metabolism also regulates differentiation and effector functions of immune cells. ...Here, we review what is known regarding the metabolic requirements for NK cell activation, focusing on NK cell production of interferon-gamma (IFN-γ). ...
Metabolism is critical for a host of cellular functions and provides a source of intracellular energy. It has been recognized recentl
The duration of in vitro stimulation with recall antigens determines the subset distribution of interferon-gamma-producing lymphoid cells: a kinetic analysis using the Interferon-gamma Secretion Assay.
Desombere I, et al. J Immunol Methods 2005. PMID 15992817
No correlation was found between the kinetics of total number of interferon-gamma-producing cells and the changes of concentrations of interferon-gamma in the culture supernatants. Interferon-gamma levels in culture supernatants correlated strongly with the kinetics of T(H) lymphocytes (CD3+, CD4+), CTL (CD3+, CD8+), and NKT cells (CD3+, CD56+). ...
No correlation was found between the kinetics of total number of interferon-gamma-producing cells and the changes of concentra …
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