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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
2003 5
2004 3
2005 18
2006 306
2007 785
2008 867
2009 988
2010 1067
2011 1193
2012 1411
2013 1471
2014 1602
2015 1624
2016 1605
2017 1575
2018 1582
2019 704
2020 8
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14,402 results
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Page 1
Interleukin-1beta (IL-1beta) processing pathway.
Weber A, et al. Sci Signal 2010 - Review. PMID 20086236 Free article.
Once activated, it orchestrates the inflammatory response by secreting proinflammatory cytokines, such as interleukin-1 (IL-1)-type cytokines, in particular IL-1beta. ...Here, we describe the essential components of the NALP3-inflammasome that control processing and release of IL-1beta....
Once activated, it orchestrates the inflammatory response by secreting proinflammatory cytokines, such as interleukin-1 (IL-1)-type c …
Inflammasome activation and assembly at a glance
Malik A and Kanneganti TD. J Cell Sci 2017 - Review. PMID 29196474 Free PMC article.
The inflammasome platform leads to activation of caspase-1 through proximity-induced self-cleavage, which further induces maturation of interleukins 1β and 18 (IL-1β and IL-18) through proteolytic cleavage of pro-IL-1β and pro-IL-18. ...
The inflammasome platform leads to activation of caspase-1 through proximity-induced self-cleavage, which further induces maturation of i
Function and regulation of IL-1α in inflammatory diseases and cancer
Malik A and Kanneganti TD. Immunol Rev 2018 - Review. PMID 29247991 Free PMC article.
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. ...
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and c …
The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Evavold CL, et al. Immunity 2018. PMID 29195811 Free PMC article.
The interleukin-1 (IL-1) family cytokines are cytosolic proteins that exhibit inflammatory activity upon release into the extracellular space. ...
The interleukin-1 (IL-1) family cytokines are cytosolic proteins that exhibit inflammatory activity upon release into the extracellul …
Inflammasomes in the lung
Pinkerton JW, et al. Mol Immunol 2017 - Review. PMID 28129896
Mechanisms of interleukin-1beta release.
Eder C. Immunobiology 2009 - Review. PMID 19250700
Interleukin-1beta (IL-1beta) is a potent proinflammatory cytokine that initiates and amplifies a wide variety of effects associated with innate immunity and host responses to microbial invasion and tissue injury. ...IL-1beta is first synthesized as biologically inactive pro-IL-1beta, then processed into mature, biologically active IL-1beta by caspase-1, and subsequently released into the extracellular milieu. ...
Interleukin-1beta (IL-1beta) is a potent proinflammatory cytokine that initiates and amplifies a wide variety of effect
Understanding the mechanism of IL-1β secretion
Lopez-Castejon G and Brough D. Cytokine Growth Factor Rev 2011 - Review. PMID 22019906 Free PMC article.
The cytokine interleukin-1β (IL-1β) is a key mediator of the inflammatory response. Essential for the host-response and resistance to pathogens, it also exacerbates damage during chronic disease and acute tissue injury. ...
The cytokine interleukin-1β (IL-1β) is a key mediator of the inflammatory response. Essential for the host-response and resistance to …
The role of IL-1B in breast cancer bone metastasis
Tulotta C and Ottewell P. Endocr Relat Cancer 2018 - Review. PMID 29760166 Free PMC article.
Interleukin (IL)-1B is a pro-inflammatory cytokine whose expression in primary tumours has been identified as a potential biomarker for predicting breast cancer patients at increased risk for developing bone metastasis. ...
Interleukin (IL)-1B is a pro-inflammatory cytokine whose expression in primary tumours has been identified as a potential biomarker f
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