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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1982 3
1983 8
1984 19
1985 33
1986 65
1987 116
1988 168
1989 231
1990 235
1991 233
1992 274
1993 237
1994 218
1995 212
1996 182
1997 157
1998 143
1999 147
2000 134
2001 111
2002 117
2003 114
2004 94
2005 102
2006 87
2007 91
2008 89
2009 91
2010 63
2011 68
2012 73
2013 60
2014 73
2015 50
2016 50
2017 40
2018 40
2019 17
2020 0
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4,161 results
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Page 1
Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer.
Rosalia RA, et al. Curr Opin Chem Biol 2014 - Review. PMID 25271022 Free article.
The use of interleukin-2 (IL-2) for the stimulation of an effector immune response against metastatic cancer dates back to the early 1980s. ...
The use of interleukin-2 (IL-2) for the stimulation of an effector immune response against metastatic cancer dates back to the early …
Interleukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer.
Whittington R and Faulds D. Drugs 1993 - Review. PMID 7693434
Recombinant interleukin-2 (IL-2) products (e.g. aldesleukin, teceleukin) are nonglycosylated, modified forms of the endogenous compound. ...The interaction of IL-2 with the IL-2 receptor induces proliferation and differentiation of a number of T lymphocyte subsets, and stimulates a cytokine cascade that includes various interleukins, interferons and tumour necrosis factors. ...
Recombinant interleukin-2 (IL-2) products (e.g. aldesleukin, teceleukin) are nonglycosylated, modified forms of the endogenous compou …
Low-Dose IL-2 in the Treatment of Lupus
Mizui M and Tsokos GC. Curr Rheumatol Rep 2016 - Review. PMID 27734211
Recent extensive research on interleukin-2 (IL-2)/IL-2 receptor (IL-2R) biology has revealed its critical role in the regulation of immune tolerance by influencing regulatory T (Treg) cell functions and survival. ...
Recent extensive research on interleukin-2 (IL-2)/IL-2 receptor (IL-2R) biology has revealed its critical role in the regulation of i …
Interleukin-2: use in solid tumors.
Bukowski RM, et al. Stem Cells 1993 - Review. PMID 8457777
Recombinant interleukin-2 (rIL-2) is a cytokine that has a central immunoregulatory role in controlling T cell function and growth. ...
Recombinant interleukin-2 (rIL-2) is a cytokine that has a central immunoregulatory role in controlling T cell function and growth. . …
The use of interleukin-2 in human immunodeficiency virus infection.
Anaya JP and Sias JJ. Pharmacotherapy 2005 - Review. PMID 15767224
In light of this incomplete success, interleukin (IL)-2 is being evaluated as adjunctive therapy to antiretroviral therapy. The agent has demonstrated mixed yet promising results in restoring immune function in patients who are HIV positive....
In light of this incomplete success, interleukin (IL)-2 is being evaluated as adjunctive therapy to antiretroviral therapy. The agent …
Interleukin-2 and leukemia.
Goodman M, et al. Leukemia 1998 - Review. PMID 9823939 Free article.
However, there remains a lack of correlation between the biologic and clinical effects of interleukin-2. The clinical activity of interleukin-2 appears to be greatest in myeloid leukemias. ...Large randomized studies are necessary to explore the role of interleukin-2 in leukemia....
However, there remains a lack of correlation between the biologic and clinical effects of interleukin-2. The clinical activity of …
Interleukin-2 Can Cure Kidney Cancer.
Dutcher JP and Wiernik PH. Oncologist 2018. PMID 30104291 Free PMC article.
Interleukin-2 toxicity.
Siegel JP and Puri RK. J Clin Oncol 1991 - Review. PMID 2066765
Because of the ability of interleukin-2 (IL-2) to support the proliferation and activation of numerous types of immunocompetent cells and to support the survival of adoptively transferred lymphocytes, there has been considerable interest in its use in the immunotherapy of malignancies. ...
Because of the ability of interleukin-2 (IL-2) to support the proliferation and activation of numerous types of immunocompetent cells …
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