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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 4
1982 3
1983 10
1984 4
1985 21
1986 15
1987 43
1988 142
1989 357
1990 529
1991 825
1992 1134
1993 1096
1994 1395
1995 1426
1996 1425
1997 1511
1998 1522
1999 1512
2000 1764
2001 1749
2002 1771
2003 1914
2004 1963
2005 2211
2006 2292
2007 2368
2008 2675
2009 2942
2010 3107
2011 3482
2012 3794
2013 3957
2014 4048
2015 4061
2016 3827
2017 3783
2018 3236
2019 1526
2020 27
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62,645 results
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Page 1
Interleukin-6 and Interleukin-10 in mood disorders: A population-based study.
Wiener CD, et al. Psychiatry Res 2019. PMID 31207853
MDD and BD groups showed significantly higher serum IL-6 levels (p ≤ 0.001) and IL-10 levels (p ≤ 0.001) when compared to healthy control group. ...Covariance analysis showed that mood disorders alone, increase both interleukin levels (IL-6, p = 0.019; and IL-10, p = 0.026), whilst the interaction of mood disorders and suicide risk or anxiety disorders did not. ...
MDD and BD groups showed significantly higher serum IL-6 levels (p ≤ 0.001) and IL-10 levels (p ≤ 0.001) when compared to healthy con …
The interleukin-6 regulates the function of monocytes/macrophages (MO/MФ) via the interleukin-6 receptor β in ayu (Plecoglossus altivelis).
Zhu K, et al. Fish Shellfish Immunol 2019. PMID 31326589
Interleukin-6 (IL-6) is one of the most pleiotropic cytokines because of its wide range of effects on cells of the immune and non-immune systems in the body. ...Recombinant PaIL-6 protein (rPaIL-6) treatment enhanced pro-inflammatory cytokine expression. Ayu interleukin-6 receptor β (PaIL-6Rβ) knockdown resulted in decreased pro-inflammatory cytokine expression in MO/MФ treated with rPaIL-6, whereas no significant changes were observed after ayu interleukin-6 receptor α (PaIL-6Rα) knockdown in MO/MФ. ...
Interleukin-6 (IL-6) is one of the most pleiotropic cytokines because of its wide range of effects on cells of the immu
Plasma interleukin-6 concentration for the diagnosis of sepsis in critically ill adults.
Molano Franco D, et al. Cochrane Database Syst Rev 2019. PMID 31038735 Free PMC article.
OBJECTIVES: To determine the diagnostic accuracy of plasma interleukin-6 (IL-6) concentration for the diagnosis of bacterial sepsis in critically ill adults. ...AUTHORS' CONCLUSIONS: Our evidence assessment of plasma interleukin-6 concentrations for the diagnosis of sepsis in critically ill adults reveals several limitations. ...
OBJECTIVES: To determine the diagnostic accuracy of plasma interleukin-6 (IL-6) concentration for the diagnosis of bact …
The relationship between intoxication severity and blood interleukin 6, interleukin 10 and CRP levels in carbon monoxide-poisoned patients.
Akcali G, et al. Undersea Hyperb Med 2018 - Clinical Trial. PMID 31158931
We measured high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and interleukin-10 (IL-10) levels in patients with different degrees of CO poisoning. ...Compared to admission levels, IL-6 levels were higher at six hours (P=0.014). The patients were grouped according to treatment type (NBO2, HBO2) and history of syncope, but no significant differences were detected in patient subgroups regarding IL-6, IL-10 and hs-CRP levels. ...
We measured high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and interleukin-10 (IL-10) levels …
Association between interleukin-6 gene polymorphisms and febrile seizure risk: A meta-analysis.
Chen Q, et al. Medicine (Baltimore) 2019. PMID 31574823 Free PMC article.
BACKGROUND: The association between plasma interleukin-6 (IL-6) levels and the development of febrile seizures (FS) has been reported in multiple previous studies, which showed significantly higher serum IL-6 levels in FS patients than in control patients. ...Although IL-6 gene polymorphisms may be associated with FS risk, this association remains a matter of debate. OBJECTIVE: Considering the lack of meta-analyses addressing the possible association between IL-6 gene polymorphisms and the risk of FS, we aimed to perform a meta-analysis to determine the association of IL-6 gene polymorphisms (-572, -174, -597) with the risk of FS. ...
BACKGROUND: The association between plasma interleukin-6 (IL-6) levels and the development of febrile seizures (FS) has …
Profiles and Predictive Values of Interleukin-6 in Aortic Dissection: a Review.
Yuan SM. Braz J Cardiovasc Surg 2019 - Review. PMID 31112020 Free PMC article.
Clinical observations demonstrated that patients with AD had an elevated interleukin (IL)-6 level in comparison to hypertensive or healthy controls. ...Therapeutic interventions aiming at attenuating the inflammatory status by IL-6 neutralization could effectively decrease the IL-6 level and thus reverse the progression of the disorder of AD patient. ...
Clinical observations demonstrated that patients with AD had an elevated interleukin (IL)-6 level in comparison to hypertensiv …
Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review.
Bobbo VCD, et al. Biomed Res Int 2019. PMID 31534953 Free PMC article.
Interleukin-6 (IL-6) is a unique cytokine that can play both pro- and anti-inflammatory roles depending on the anatomical site and conditions under which it has been induced. ...However, little is known about the role of IL-6 in the regulation of hypothalamic microglia. In this systematic review, we asked what types of conditions and stimuli could modulate microglial IL-6 expression in murine model. ...
Interleukin-6 (IL-6) is a unique cytokine that can play both pro- and anti-inflammatory roles depending on the anatomic
Interleukin-6 serum level and gene polymorphism in keloid patients.
Abdu Allah AMK, et al. Cell Mol Biol (Noisy-le-grand) 2019. PMID 31304905
Persistent deregulated IL-6 synthesis causes the development of various diseases. This study aim to investigate interleukin 6 (IL-6) serum level and gene polymorphism in a sample of Egyptian patients having keloid. ...The higher serum levels of IL-6 were associated with GG genotype (104.84±19.12) followed by CG (57.64±35.38) genotype (P<0.001). ...
Persistent deregulated IL-6 synthesis causes the development of various diseases. This study aim to investigate interleukin
Tumor-associated macrophage related interleukin-6 in cerebrospinal fluid as a prognostic marker for glioblastoma.
Hori T, et al. J Clin Neurosci 2019. PMID 31327593
Interleukin-6 (IL-6) is one of the pleiotropic cytokines and has received attention as a critical factor implicated in the invasion and the angiogenesis of various cancers. In glioma, IL-6 is known to be associated with the prognosis; however, the roles of IL-6 in cerebrospinal fluid (CSF) has not been studied sufficiently. ...
Interleukin-6 (IL-6) is one of the pleiotropic cytokines and has received attention as a critical factor implicated in
Influence of Interleukin-6 (IL-6) Promoter Gene Polymorphisms (-174G>C, -572G>C, and -597G>A) on IL-6 Plasma Levels and Their Impact in the Development of Acute Ischemic Stroke in Young Indians.
Akhter MS, et al. Clin Appl Thromb Hemost 2019. PMID 31215220 Free PMC article.
This study aimed to determine whether there is an influence of interleukin 6 (IL-6) gene promoter polymorphisms on IL-6 plasma levels and its role in the development of ischemic stroke in young Indians. ...Interleukin 6 is an inflammatory marker that is considerably influenced by nongenetic factors and is not a good candidate gene for studying genetic components associated with ischemic stroke. ...
This study aimed to determine whether there is an influence of interleukin 6 (IL-6) gene promoter polymorphisms on IL- …
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