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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 3
1967 5
1968 9
1969 9
1970 20
1971 19
1972 34
1973 31
1974 28
1975 29
1976 31
1977 26
1978 36
1979 30
1980 38
1981 38
1982 34
1983 36
1984 45
1985 48
1986 59
1987 53
1988 51
1989 63
1990 55
1991 55
1992 72
1993 77
1994 89
1995 86
1996 104
1997 127
1998 147
1999 145
2000 195
2001 176
2002 161
2003 190
2004 204
2005 249
2006 276
2007 272
2008 289
2009 331
2010 365
2011 370
2012 390
2013 408
2014 431
2015 397
2016 432
2017 389
2018 420
2019 225
2020 10
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7,287 results
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Page 1
Probiotics, gut microbiota, and their influence on host health and disease
Sánchez B, et al. Mol Nutr Food Res 2017 - Review. PMID 27500859
The gastrointestinal tract of mammals hosts a high and diverse number of different microorganisms, known as intestinal microbiota. ...The aim of this review was to compile the molecular mechanisms underlying the beneficial effects of probiotics, mainly through their interaction with the intestinal microbiota and with the intestinal mucosa. ...
The gastrointestinal tract of mammals hosts a high and diverse number of different microorganisms, known as intestinal microbiota. .. …
Mucosal immunity to pathogenic intestinal bacteria.
Perez-Lopez A, et al. Nat Rev Immunol 2016 - Review. PMID 26898110
The intestinal mucosa is a particularly dynamic environment in which the host constantly interacts with trillions of commensal microorganisms, known as the microbiota, and periodically interacts with pathogens of diverse nature. ...Instead, we aim to provide a representative overview of how the intestinal immune system responds to pathogenic bacteria....
The intestinal mucosa is a particularly dynamic environment in which the host constantly interacts with trillions of commensal …
The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation.
Hiippala K, et al. Nutrients 2018 - Review. PMID 30060606 Free PMC article.
The intestinal microbiota, composed of pro- and anti-inflammatory microbes, has an essential role in maintaining gut homeostasis and functionality. ...These include the already well-known bifidobacteria, which use extracellular structures or secreted substances to promote intestinal health. ...
The intestinal microbiota, composed of pro- and anti-inflammatory microbes, has an essential role in maintaining gut homeostasis and …
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier.
Martens EC, et al. Nat Rev Microbiol 2018 - Review. PMID 29904082
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. ...In this Review, we discuss the current state of knowledge of the complex interactions of commensal microorganisms with the intestinal mucosal barrier, and we discuss strategies used by pathogenic microorganisms to establish infection by either exploiting different epithelial cell lineages or disrupting the mucous layer, as well as the role of defects in mucus production in chronic disease....
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and func …
Replication of human noroviruses in stem cell-derived human enteroids
Ettayebi K, et al. Science 2016. PMID 27562956 Free PMC article.
We report the successful cultivation of multiple HuNoV strains in enterocytes in stem cell-derived, nontransformed human intestinal enteroid monolayer cultures. Bile, a critical factor of the intestinal milieu, is required for strain-dependent HuNoV replication. Lack of appropriate histoblood group antigen expression in intestinal cells restricts virus replication, and infectivity is abrogated by inactivation (e.g., irradiation, heating) and serum neutralization. ...
We report the successful cultivation of multiple HuNoV strains in enterocytes in stem cell-derived, nontransformed human intestinal e …
The role of microbiota in cancer therapy
Perez-Chanona E and Trinchieri G. Curr Opin Immunol 2016 - Review. PMID 26820225 Free PMC article.
The gut flora as a forgotten organ
O'Hara AM and Shanahan F. EMBO Rep 2006 - Review. PMID 16819463 Free PMC article.
The intestinal microflora is a positive health asset that crucially influences the normal structural and functional development of the mucosal immune system. Mucosal immune responses to resident intestinal microflora require precise control and an immunosensory capacity for distinguishing commensal from pathogenic bacteria. ...
The intestinal microflora is a positive health asset that crucially influences the normal structural and functional development of th …
The Gut-Lung Axis in Respiratory Disease
Marsland BJ, et al. Ann Am Thorac Soc 2015 - Review. PMID 26595731
There is a vital cross-talk between the mucosal tissues of our body, as exemplified by intestinal complications during respiratory disease and vice versa. ...In this review, we highlight how changes in the intestinal microenvironment, with a particular focus on the intestinal microbiota, impact upon respiratory disease....
There is a vital cross-talk between the mucosal tissues of our body, as exemplified by intestinal complications during respiratory di …
Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer.
Chen W, et al. PLoS One 2012. PMID 22761885 Free PMC article.
The structures of the intestinal lumen microbiota and mucosa-adherent microbiota were different in CRC patients compared to matched microbiota in healthy individuals. ...However, mucosa-associated microbiota potentially affects CRC risk primarily through direct interaction with the host....
The structures of the intestinal lumen microbiota and mucosa-adherent microbiota were different in CRC patients compared to ma …
7,287 results
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