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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 2
1965 25
1966 85
1967 126
1968 162
1969 192
1970 205
1971 213
1972 199
1973 216
1974 283
1975 216
1976 191
1977 177
1978 193
1979 213
1980 202
1981 214
1982 195
1983 220
1984 281
1985 314
1986 263
1987 287
1988 277
1989 292
1990 304
1991 319
1992 365
1993 347
1994 345
1995 442
1996 439
1997 465
1998 542
1999 510
2000 567
2001 551
2002 587
2003 562
2004 636
2005 692
2006 728
2007 837
2008 810
2009 835
2010 937
2011 913
2012 930
2013 1049
2014 1042
2015 964
2016 878
2017 821
2018 897
2019 488
2020 10
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23,411 results
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Page 1
The Intestinal Stem Cell Niche: Homeostasis and Adaptations.
Santos AJM, et al. Trends Cell Biol 2018 - Review. PMID 30195922 Free PMC article.
The intestinal epithelium is a rapidly renewing cellular compartment. This constant regeneration is a hallmark of intestinal homeostasis and requires a tightly regulated balance between intestinal stem cell (ISC) proliferation and differentiation. ...Understanding niche adaptations that maintain ISC activity during homeostatic renewal and injury-induced intestinal regeneration is therefore a major and ongoing focus for stem cell biology. ...
The intestinal epithelium is a rapidly renewing cellular compartment. This constant regeneration is a hallmark of intestinal h …
Potential Use of Human Stem Cell-Derived Intestinal Organoids to Study Inflammatory Bowel Diseases.
Dotti I and Salas A. Inflamm Bowel Dis 2018 - Review. PMID 30169820 Free PMC article.
The intestinal epithelial barrier plays a major role in IBD, contributing to its pathogenesis, evolution, and perpetuation over time. ...Recently, however, a methodology for generating stable human 3D epithelial cultures directly from adult intestinal stem cells was established. ...
The intestinal epithelial barrier plays a major role in IBD, contributing to its pathogenesis, evolution, and perpetuation over time. …
Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium.
Günther C, et al. Gut 2013 - Review. PMID 22689519
Intestinal epithelial cells (IEC) are organised as a single cell layer which covers the intestine. Their primary task is to absorb nutrients present in the intestinal lumen. ...Moreover, an apoptosis-independent mode of programmed cell death, termed necroptosis, has been identified and described in the intestinal epithelium. ...
Intestinal epithelial cells (IEC) are organised as a single cell layer which covers the intestine. Their primary task is to absorb nu
A study of the damage of the intestinal mucosa barrier structure and function of Ctenopharyngodon idella with Aeromonas hydrophila.
Kong WG, et al. Fish Physiol Biochem 2017. PMID 28425012
The aim of this study is to explore the effect of Aeromonas hydrophila on the intestinal mucosal barrier structure and intestinal permeability in grass carp (Ctenopharyngodon idella). ...The permeability of intestinal mucosa was determined using Evans blue (EB) and D-lactic acid. The results indicated that the levels of EB and serum D-lactic acid were significantly increased after infection with A. hydrophila (p < 0.05). ...
The aim of this study is to explore the effect of Aeromonas hydrophila on the intestinal mucosal barrier structure and intestinal
Fructooligosaccharide intake promotes epigenetic changes in the intestinal mucosa in growing and ageing rats.
Lima GC, et al. Eur J Nutr 2018. PMID 28324207
PURPOSE: The aim of this study was to investigate the relationship between fructooligosaccharide (FOS) intake at different life stages of Wistar rats and its stimulatory effects on intestinal parameters. ...CONCLUSION: These results suggest that dietary FOS intake may be beneficial for some parameters of intestinal health in growing rats....
PURPOSE: The aim of this study was to investigate the relationship between fructooligosaccharide (FOS) intake at different life stages of Wi …
In Vitro and In Vivo Approaches to Determine Intestinal Epithelial Cell Permeability.
Li BR, et al. J Vis Exp 2018. PMID 30394372 Free PMC article.
The intestinal barrier defends against pathogenic microorganism and microbial toxin. Its function is regulated by tight junction permeability and epithelial cell integrity, and disruption of the intestinal barrier function contributes to progression of gastrointestinal and systemic disease. ...Oral gavage provides an accurate dose, and therefore is the preferred method to measure the intestinal permeability in vivo. ...
The intestinal barrier defends against pathogenic microorganism and microbial toxin. Its function is regulated by tight junction perm …
A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro.
Leonard F, et al. Mol Pharm 2010. PMID 20809575
., Caco-2 cell line) are widely used to assess the absorption of drug molecules across healthy intestinal mucosa, there are no suitable in vitro models of the intestinal barrier in the state of inflammation. ...We here report on the development of a complex in vitro model of the inflamed intestinal mucosa, starting with the selection of suitable enterocyte cell line and proinflammatory stimulus and progressing to the setup and characterization of a three-dimensional coculture of human intestinal epithelial cells and immunocompetent macrophages and dendritic cells. ...
., Caco-2 cell line) are widely used to assess the absorption of drug molecules across healthy intestinal mucosa, there are no …
Endoscopic Duodenal Mucosal Resurfacing for the Treatment of Type 2 Diabetes
Hadefi A, et al. Dig Dis 2018. PMID 29680836 Free article.
Experimental evidence in animals has demonstrated that intestinal bypass surgery of the upper small intestine, particularly the duodenum, has an important role in glucose homoeostasis. ...
Experimental evidence in animals has demonstrated that intestinal bypass surgery of the upper small intestine, particularly the duode …
23,411 results
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