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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1973 2
1974 1
1975 18
1976 30
1977 19
1978 35
1979 29
1980 26
1981 50
1982 75
1983 67
1984 83
1985 90
1986 126
1987 146
1988 166
1989 197
1990 219
1991 262
1992 317
1993 384
1994 458
1995 512
1996 507
1997 566
1998 631
1999 702
2000 784
2001 829
2002 1019
2003 1139
2004 1321
2005 1596
2006 1820
2007 2021
2008 2168
2009 2224
2010 2790
2011 3301
2012 3390
2013 3444
2014 3416
2015 3581
2016 3307
2017 3155
2018 3089
2019 3211
2020 3206
2021 2858
2022 654
2023 221
2024 61

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53,925 results

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Page 1
Pharmacological Inhibitors of the NLRP3 Inflammasome.
Zahid A, Li B, Kombe AJK, Jin T, Tao J. Zahid A, et al. Front Immunol. 2019 Oct 25;10:2538. doi: 10.3389/fimmu.2019.02538. eCollection 2019. Front Immunol. 2019. PMID: 31749805 Free PMC article. Review.
Cyclin D-CDK4/6 functions in cancer.
Gao X, Leone GW, Wang H. Gao X, et al. Adv Cancer Res. 2020;148:147-169. doi: 10.1016/bs.acr.2020.02.002. Epub 2020 Apr 2. Adv Cancer Res. 2020. PMID: 32723562 Review.
Syk inhibitors.
Chihara K, Kimura Y, Honjo C, Takeuchi K, Sada K. Chihara K, et al. Nihon Rinsho Meneki Gakkai Kaishi. 2013;36(4):197-202. doi: 10.2177/jsci.36.197. Nihon Rinsho Meneki Gakkai Kaishi. 2013. PMID: 23994797 Review. English, Japanese.
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Hillig RC, Sautier B, Schroeder J, Moosmayer D, Hilpmann A, Stegmann CM, Werbeck ND, Briem H, Boemer U, Weiske J, Badock V, Mastouri J, Petersen K, Siemeister G, Kahmann JD, Wegener D, Böhnke N, Eis K, Graham K, Wortmann L, von Nussbaum F, Bader B. Hillig RC, et al. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560. doi: 10.1073/pnas.1812963116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683722 Free PMC article.
G protein antagonists.
Freissmuth M, Waldhoer M, Bofill-Cardona E, Nanoff C. Freissmuth M, et al. Trends Pharmacol Sci. 1999 Jun;20(6):237-45. doi: 10.1016/s0165-6147(99)01337-1. Trends Pharmacol Sci. 1999. PMID: 10366866 Review.
Allosteric small-molecule kinase inhibitors.
Wu P, Clausen MH, Nielsen TE. Wu P, et al. Pharmacol Ther. 2015 Dec;156:59-68. doi: 10.1016/j.pharmthera.2015.10.002. Epub 2015 Oct 24. Pharmacol Ther. 2015. PMID: 26478442 Review.
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Dar HH, Mikulska-Ruminska K, Tyurina YY, Luci DK, Yasgar A, Samovich SN, Kapralov AA, Souryavong AB, Tyurin VA, Amoscato AA, Epperly MW, Shurin GV, Standley M, Holman TR, St Croix CM, Watkins SC, VanDemark AP, Rana S, Zakharov AV, Simeonov A, Marugan J, Mallampalli RK, Wenzel SE, Greenberger JS, Rai G, Bayir H, Bahar I, Kagan VE. Dar HH, et al. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218896120. doi: 10.1073/pnas.2218896120. Epub 2023 Jun 16. Proc Natl Acad Sci U S A. 2023. PMID: 37327313 Free PMC article.
A STAT inhibitor patent review: progress since 2011.
Lai PS, Rosa DA, Magdy Ali A, Gómez-Biagi RF, Ball DP, Shouksmith AE, Gunning PT. Lai PS, et al. Expert Opin Ther Pat. 2015;25(12):1397-421. doi: 10.1517/13543776.2015.1086749. Epub 2015 Sep 22. Expert Opin Ther Pat. 2015. PMID: 26394986 Review.
53,925 results
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