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Page 1
Discrimination and Calibration of Clinical Prediction Models: Users' Guides to the Medical Literature.
Alba AC, Agoritsas T, Walsh M, Hanna S, Iorio A, Devereaux PJ, McGinn T, Guyatt G. Alba AC, et al. JAMA. 2017 Oct 10;318(14):1377-1384. doi: 10.1001/jama.2017.12126. JAMA. 2017. PMID: 29049590
Such prediction models should be characterized by adequately discriminating between patients who will have an event and those who will not and by adequate calibration ensuring accurate prediction of absolute risk. This Users' Guide will help clinicians understand th …
Such prediction models should be characterized by adequately discriminating between patients who will have an event and those who will not a …
How to use a subgroup analysis: users' guide to the medical literature.
Sun X, Ioannidis JP, Agoritsas T, Alba AC, Guyatt G. Sun X, et al. JAMA. 2014 Jan 22-29;311(4):405-11. doi: 10.1001/jama.2013.285063. JAMA. 2014. PMID: 24449319
These criteria will help clinicians deciding whether to use subgroup analyses to guide their patient care....
These criteria will help clinicians deciding whether to use subgroup analyses to guide their patient care....
How to Interpret and Use a Clinical Practice Guideline or Recommendation: Users' Guides to the Medical Literature.
Brignardello-Petersen R, Carrasco-Labra A, Guyatt GH. Brignardello-Petersen R, et al. JAMA. 2021 Oct 19;326(15):1516-1523. doi: 10.1001/jama.2021.15319. JAMA. 2021. PMID: 34665198
In the guideline development process, a panel of experts formulates recommendation questions that guide the retrieval of evidence that is used to inform the recommendations. Typically, methods of guideline development, a summary of the supporting evidence, and a justificat …
In the guideline development process, a panel of experts formulates recommendation questions that guide the retrieval of evidence tha …
How to Use and Interpret the Results of a Platform Trial: Users' Guide to the Medical Literature.
Park JJH, Detry MA, Murthy S, Guyatt G, Mills EJ. Park JJH, et al. JAMA. 2022 Jan 4;327(1):67-74. doi: 10.1001/jama.2021.22507. JAMA. 2022. PMID: 34982138
Platform trials have recently been used in investigations of evolving therapies for patients with COVID-19. The purpose of this Users' Guide to the Medical Literature is to describe fundamental concepts of platform trials and master protocols and review issues in th …
Platform trials have recently been used in investigations of evolving therapies for patients with COVID-19. The purpose of this Users …
Adjusted Analyses in Studies Addressing Therapy and Harm: Users' Guides to the Medical Literature.
Agoritsas T, Merglen A, Shah ND, O'Donnell M, Guyatt GH. Agoritsas T, et al. JAMA. 2017 Feb 21;317(7):748-759. doi: 10.1001/jama.2016.20029. JAMA. 2017. PMID: 28241362
Its principle is to use measurement of risk factors to create prognostically homogeneous groups and to combine effect estimates across groups.The purpose of this Users' Guide is to introduce readers to fundamental concepts underlying adjustment as a way of dealing w …
Its principle is to use measurement of risk factors to create prognostically homogeneous groups and to combine effect estimates across group …
41 results