"JOR Spine"[Journal] - Search Results

Year	Number of Results
2018	33
2019	27
2020	59
2021	49
2022	47
2023	74
2024	100
2025	126
2026	41

1

A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain-Inducing Nucleus Pulposus Cell Emergence.

Kaneda G, Wechsler JT, Chavez M, Sheyn J, Cheema K, Shen C, Rigo De Righi D, Wang L, Hsu YC, Avalos P, Xie Y, Tawackoli W, Floyd C, Li D, Sheyn D. Kaneda G, et al. JOR Spine. 2026 Jul 9;9(3):e70200. doi: 10.1002/jsp2.70200. eCollection 2026 Sep. JOR Spine. 2026. PMID: 42428568 Free PMC article.

2

Large Language Models in Preclinical Spine Research: A Scoping Review and Expert Perspective on Evidence-Aware Experimental Workflows.

Lang S, Motov S, Krueckel J, Scherer J, Staartjes VE, Wuertz-Kozak K. Lang S, et al. JOR Spine. 2026 Jul 8;9(3):e70203. doi: 10.1002/jsp2.70203. eCollection 2026 Sep. JOR Spine. 2026. PMID: 42422043 Free PMC article.

3

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet): Bridging Biology, Pain Phenotyping, and Trial Design.

Ambrosio L, Schol J, Ruiz-Fernandez C, Denaro V, Vadalà G, Sakai D. Ambrosio L, et al. JOR Spine. 2026 Jul 3;9(3):e70187. doi: 10.1002/jsp2.70187. eCollection 2026 Sep. JOR Spine. 2026. PMID: 42404489 Free PMC article.

4

Impact of Screw Insertion Technique on Thoracic Pedicle Screw Anchorage: Biomechanical Comparison of the Modified Slide, Slide, Funnel, and Conventional Techniques.

Lindtner RA, Krumm F, Schmoelz W, Benko J, Ellmerer AE, Pallua JD, Hoermann R, Spicher A. Lindtner RA, et al. JOR Spine. 2026 Jun 23;9(2):e70202. doi: 10.1002/jsp2.70202. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42344069 Free PMC article.

5

Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity.

Wilson N, Néill TN, McDonnell J, McDonnell E, Darwish S, Butler JS, Buckley CT. Wilson N, et al. JOR Spine. 2026 Jun 20;9(2):e70201. doi: 10.1002/jsp2.70201. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42327385 Free PMC article.

6

Pre-Conditioned Bone Marrow Mesenchymal Stromal Cell-Derived Secretome Exerts an Anti-Inflammatory Effect on Degenerative Nucleus Pulposus Cells In Vitro.

Tilotta V, Vadalà G, Ambrosio L, Di Giacomo G, Cicione C, Russo F, Papalia R, Denaro V. Tilotta V, et al. JOR Spine. 2026 Jun 20;9(2):e70199. doi: 10.1002/jsp2.70199. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42327384 Free PMC article.

7

Explainable Supervised Learning Classification Model Using Diffusion Tensor Imaging Predicts Postoperative Outcomes in Cervical Spondylotic Myelopathy: A Preliminary Study.

Peng Y, Zhang Z, Zhang Z, Shi K, Wang R, Liu Y, Zhang L. Peng Y, et al. JOR Spine. 2026 Jun 10;9(2):e70197. doi: 10.1002/jsp2.70197. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42281788 Free PMC article.

8

Uncertainty Quantification of Central Canal Stenosis Deep Learning Classifier From Lumbar Sagittal T2-Weighted MRI.

Brenzikofer A, Monzon M, Galbusera F, Manjaly ZM, Cina A, Jutzeler CR. Brenzikofer A, et al. JOR Spine. 2026 Jun 8;9(2):e70184. doi: 10.1002/jsp2.70184. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42273232 Free PMC article.

9

Quantitative Disk and Metabolic Bone PET-MRI for Understanding Disk-Endplate Crosstalk in Degeneration of the Lumbar Spine.

Kreutzinger V, Ziegeler K, Han M, Chin CT, Bhattacharjee R, Remick I, Bahroos E, Majumdar S. Kreutzinger V, et al. JOR Spine. 2026 Jun 8;9(2):e70188. doi: 10.1002/jsp2.70188. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42267131 Free PMC article.

10

Application of Statistical Shape Models to Standard Lumbar MRI for Stenosis Treatment Stratification: Severe Versus Normal Stenosis.

Foltz MH, Seidenstein A, Durand WM, Jain A, Middendorf JM. Foltz MH, et al. JOR Spine. 2026 Jun 7;9(2):e70189. doi: 10.1002/jsp2.70189. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42267130 Free PMC article.

11

Comparative Analysis of Dual-miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair.

Néill TN, Wilson N, McDonnell J, O'Brien FJ, Curtin CM, Dixon JE, Brama PAJ, Buckley CT. Néill TN, et al. JOR Spine. 2026 Jun 5;9(2):e70198. doi: 10.1002/jsp2.70198. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42253284 Free PMC article.

12

Diagnostic Features of Discogenic Low Back Pain: A Narrative Review and Suggested Areas for Future Research and Clinical Practice.

Peters WR, Diwan AD, Zotti MG. Peters WR, et al. JOR Spine. 2026 May 28;9(2):e70195. doi: 10.1002/jsp2.70195. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42253287 Free PMC article. Review.

13

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro.

Kanelis E, Nüesch A, Snuggs J, Le Maitre CL, Alexopoulos LG. Kanelis E, et al. JOR Spine. 2026 Mar 27;9(2):e70165. doi: 10.1002/jsp2.70165. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42253286 Free PMC article.

14

Spinal Implant-Associated Infection in Type 2 and Type 1 Diabetes: Phenotype-Specific Inflammatory Features and Therapeutic Response to Semaglutide.

Olson TE, Lloyd TS, Hamad CD, Chun RF, Wiener J, Golzar A, Mehany J, Shahamatdar S, Kittredge A, Pearce L, Francis KP, Obeidin F, Holly LT, Yeaman MR, Adams JS, Bernthal NM, Sheppard WL. Olson TE, et al. JOR Spine. 2026 May 28;9(2):e70196. doi: 10.1002/jsp2.70196. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42253285 Free PMC article.

15

Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease.

Gonzalez CE, Schurman CA, Wilson KA, Schilling B, Ellerby LM, Tang SY. Gonzalez CE, et al. JOR Spine. 2026 Mar 27;9(2):e70171. doi: 10.1002/jsp2.70171. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42253283 Free PMC article.

16

Lifetime Physical Loading and Magnetic Resonance-Derived Intervertebral Disc Health in Adults With Chronic Low Back Pain: A Cross-Sectional Study.

Samanna CL, Neason C, Tagliaferri SD, Mitchell UH, Caldwell M, Imran A, Nez HR, Belavý DL, Miller CT, Scott D, Mundell NL, Buntine P, Owen PJ. Samanna CL, et al. JOR Spine. 2026 May 15;9:e70186. doi: 10.1002/jsp2.70186. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42146264 Free PMC article.

17

Deletion of a Pax1 Sex-Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice.

Moody EC, Wade EM, Mizumoto S, McCallum-Loudeac J, Wilson MJ. Moody EC, et al. JOR Spine. 2026 Apr 22;9:e70177. doi: 10.1002/jsp2.70177. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42039795 Free PMC article.

18

Detrimental Effect of Low-Magnitude High-Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment.

Jansen JU, Figel F, Widmayer F, Vogt M, Ahrens M, Wilke HJ, Ignatius A, Haffner-Luntzer M, Neidlinger-Wilke C, Teixeira GQ. Jansen JU, et al. JOR Spine. 2026 Apr 22;9:e70183. doi: 10.1002/jsp2.70183. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42027793 Free PMC article.

19

Intradiscal Cutibacterium acnes Sustains Modic Type 1-Like Lesions Over Time in a Rat Lumbar Endplate Injury Model.

Heggli I, Lai A, Iliff D, Burkhard MD, Koehne N, Singh H, Huang JJ, Seifert AC, Laudier D, Bonnheim N, Rodriguez L, Jacobsen TD, Iatridis JC. Heggli I, et al. JOR Spine. 2026 Apr 22;9:e70182. doi: 10.1002/jsp2.70182. eCollection 2026 Jun. JOR Spine. 2026. PMID: 42027792 Free PMC article.

20

Platelet-Rich Fibrin Induces New Bone Formation to Promote Extreme Lateral Interbody Fusion of Spine in Rabbits.

Wang W, Li J, Wu H, Yang S, Li S, Zhang W. Wang W, et al. JOR Spine. 2026 Apr 15;9(2):e70179. doi: 10.1002/jsp2.70179. eCollection 2026 Jun. JOR Spine. 2026. PMID: 41993150 Free PMC article.

21

Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain.

LeVasseur C, Megherhi S, Mesoros M, McKernan G, Warwose R, Donaldson W, Lee JY, Sowa G, Anderst W. LeVasseur C, et al. JOR Spine. 2026 Apr 15;9(2):e70181. doi: 10.1002/jsp2.70181. eCollection 2026 Jun. JOR Spine. 2026. PMID: 41993149 Free PMC article.

22

From Concept to Clinic: Pre-Clinical Testing and Regulatory Considerations in Spine Implant Development.

Benady A, Varghese JT, Quarrington RD, Khashan M, Prusty BG, Diwan A. Benady A, et al. JOR Spine. 2026 Apr 14;9(2):e70176. doi: 10.1002/jsp2.70176. eCollection 2026 Jun. JOR Spine. 2026. PMID: 41987831 Free PMC article. Review.

23

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section.

Bhadouria N, Gawri R, Graziani G, Anderson DE, Chee AV, Dahia CL, Diwan A, Giers MB, Illien-Junger S, Kirilusha A, Nuckley DJ, Rosenzweig DH, Séguin C, Sheyn D, Teixeira GQ, Alini M, Ito K, Mauck RL, Sakai D, Bailey J, Fields AJ, Grad S, Gullbrand SE, Holguin N, Kandel R, Li Z, Li J, Martin JT, Mwale F, O'Connell GD, Purmessur D, Vo N, Zehra U, Chahine NO, Haglund L, Hoyland JA, Le Maitre CL, Lotz JC, Risbud MV, Smith LJ, Tang S, Iatridis JC, Wuertz-Kozak K, Samartzis D. Bhadouria N, et al. JOR Spine. 2026 Apr 13;9(2):e70180. doi: 10.1002/jsp2.70180. eCollection 2026 Jun. JOR Spine. 2026. PMID: 41982788 Free PMC article. No abstract available.

24

Inhibition of PLA2G15 Alleviates Palmitic Acid-Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration.

Duan L, Jiang J, Tu S, Li C, Dong Y, Li Y, Zhang W, Chen X. Duan L, et al. JOR Spine. 2026 Apr 9;9(2):e70178. doi: 10.1002/jsp2.70178. eCollection 2026 Jun. JOR Spine. 2026. PMID: 41971388 Free PMC article.

25

Feasibility of Smartphone-Derived Short-Interval Walking Tests for Monitoring Functional Recovery After Spine Surgery.

Puhakka J, Jung M, Fekete T, Loibl M, Kleinstück F, Porchet F, Ropelato M, Gocevic M, Galbusera F, Cina A, O'Riordan D, Kosola J, Haschtmann D. Puhakka J, et al. JOR Spine. 2026 Mar 24;9(1):e70173. doi: 10.1002/jsp2.70173. eCollection 2026 Mar. JOR Spine. 2026. PMID: 42022424 Free PMC article.

26

Modic Change Bone Marrow Neutrophils Are Activated and Degrade Cartilage Endplates.

Heggli I, Mengis T, Devan J, Herger N, Farshad M, Habib M, Ames CP, Distler O, Fields AJ, Dudli S. Heggli I, et al. JOR Spine. 2026 Mar 18;9(1):e70170. doi: 10.1002/jsp2.70170. eCollection 2026 Mar. JOR Spine. 2026. PMID: 42022426 Free PMC article.

27

Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI, Radiological, Histological, Biochemical, and Biomechanical Assessments.

Yusuf Y, Abbott RE, Buko EO, Chase KL, Falck AL, Pendleton D, McDermott KA, Armstrong AR, Bradley EW, Johnson CP, Ellingson AM. Yusuf Y, et al. JOR Spine. 2026 Mar 17;9(1):e70169. doi: 10.1002/jsp2.70169. eCollection 2026 Mar. JOR Spine. 2026. PMID: 42022425 Free PMC article.

28

Severity Prediction of Traumatic Cervical Spinal Cord Injury With an AI Model Based on MRI Radiomics.

Wu C, Li C, Xu G, Chen J, Wang L, Gu H, Zhang J, Hong H, Ji C, Cui Z. Wu C, et al. JOR Spine. 2026 Mar 7;9(1):e70167. doi: 10.1002/jsp2.70167. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41798294 Free PMC article.

29

Mechanosensitive Ion Channel PIEZO1 Suppresses BMP2-Induced Ossification of the Annulus Fibrosus Cells.

Shitozawa H, Nakamichi R, Yoshida A, Ueda M, Saito T, Uotani K, Oda Y, Takatori R, Yamashita K, Ozaki T. Shitozawa H, et al. JOR Spine. 2026 Mar 3;9(1):e70168. doi: 10.1002/jsp2.70168. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41783545 Free PMC article.

30

Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs.

Jansen JU, Teixeira GQ, Salzer E, Vernengo A, Grad S, Ito K, Neidlinger-Wilke C, Wilke HJ. Jansen JU, et al. JOR Spine. 2026 Mar 1;9(1):e70164. doi: 10.1002/jsp2.70164. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41777587 Free PMC article.

31

Comparing Movement Patterns and Physical Function Between Chronic Low Back Pain Patients With Nociplastic and Nociceptive Pain Categories.

Archibeck E, Harris N, Zheng P, Scheffler A, Mehling W, O'Neill C, Lotz J, O'Connell G, Bailey JF; REACH Investigators. Archibeck E, et al. JOR Spine. 2026 Mar 1;9(1):e70166. doi: 10.1002/jsp2.70166. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41777586 Free PMC article.

32

Advancing Basic and Preclinical Spine Research: Highlights From the ORS PSRS 7th International Spine Research Symposium.

Dahia CL, Smith LJ, Risbud MV, Gantenbein B. Dahia CL, et al. JOR Spine. 2026 Feb 19;9(1):e70161. doi: 10.1002/jsp2.70161. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41728056 Free PMC article.

33

Reliability of Ultrasonography to Assess Spinal Compression During Heavy Load Carriage.

Walters S, Hoffman B, Coltman CE, Walters L, Iqbal M, Mills DE. Walters S, et al. JOR Spine. 2026 Feb 10;9(1):e70137. doi: 10.1002/jsp2.70137. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41684429 Free PMC article.

34

Combined Flexion, Torsion and Compression Drive Distinct Intervertebral Disc Failure Mechanisms Under Asymmetric, High-Cycle Loading.

Šećerović A, Ristaniemi A, Crivelli F, Heub S, Alini M, Weder G, Ledroit D, Ferguson SJ, Grad S. Šećerović A, et al. JOR Spine. 2026 Feb 11;9(1):e70163. doi: 10.1002/jsp2.70163. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41684428 Free PMC article.

35

Biomechanical Analysis and Injury Prediction in Pilots With Lumbar Spondylolysis Under Different Seat Inclination Angles.

Jin M, Li Y, Wang J, Zhou Q, Liu Z, Guo P. Jin M, et al. JOR Spine. 2026 Feb 1;9(1):e70158. doi: 10.1002/jsp2.70158. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41635467 Free PMC article.

36

Advancement in the Methods for Isolating High Quality RNA From Mouse and Rat Intervertebral Disc.

Kim MKM, Lisiewski LE, Kenawy HM, Chahine NO. Kim MKM, et al. JOR Spine. 2026 Feb 2;9(1):e70157. doi: 10.1002/jsp2.70157. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41635466 Free PMC article.

37

In-Field Ecological Momentary Assessment From Wearable Motion Sensors and Self-Report in a Chronic Low Back Pain Cohort.

Bell KM, Alfikri Z, Anderst W, Clark WW, Cook HA, Darwin J, Dicianno BE, Greco CM, Hoydick J, Jakicic JM, McKernan GP, Parmanto B, Patterson CG, Piva SR, Roos RE, Schneider MJ, Sundaram M, Vo NV, Zhou L, Sowa GA. Bell KM, et al. JOR Spine. 2026 Feb 1;9(1):e70156. doi: 10.1002/jsp2.70156. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41635465 Free PMC article.

38

Complex Mechanical Loading and Pro-Inflammatory Cytokines in Intervertebral Disc Degeneration.

Crump KB, Muñoz-Moya E, de Graaf K, Bermudez-Lekerika P, Schwendener N, Zech WD, Le Maitre CL, Noailly J, Gantenbein B. Crump KB, et al. JOR Spine. 2026 Jan 26;9(1):e70159. doi: 10.1002/jsp2.70159. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41608144 Free PMC article.

39

Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells.

Wilson N, Néill TN, McDonnell J, McDonnell E, Brama PAJ, Buckley CT. Wilson N, et al. JOR Spine. 2026 Jan 14;9(1):e70160. doi: 10.1002/jsp2.70160. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41542657 Free PMC article.

40

Sex Hormones Attenuate Pro-Inflammatory Gene Expression in Nucleus Pulposus and Annulus Fibrosus Cells in a Cell-Type Specific Manner.

Hutchinson JL, Leung AE, Séguin CA. Hutchinson JL, et al. JOR Spine. 2026 Jan 9;9(1):e70152. doi: 10.1002/jsp2.70152. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41523328 Free PMC article.

41

Metastatic Spine Disease Alters Vertebral Load-To-Strength Ratios in Cancer Patients Compared to Healthy Individuals.

Anderson DE, Keko M, James J, Allaire BT, Kozono D, Doyle PF, Kang H, Caplan S, Balboni T, Spektor A, Huynh MA, Bouxsein ML, Hackney DB, Alkalay RN. Anderson DE, et al. JOR Spine. 2026 Jan 6;9(1):e70111. doi: 10.1002/jsp2.70111. eCollection 2026 Mar. JOR Spine. 2026. PMID: 41502905 Free PMC article.

42

A Multiscale Ex Vivo Method to Investigate Intervertebral Disc Strain and Fiber Recruitment in Anterolateral Bending Using 9.4T MRI-DVC and DIC Microscopy.

Slater TD, Raftery KA, van Heeswijk VM, Thambyah A, Newell N. Slater TD, et al. JOR Spine. 2025 Dec 25;8(4):e70154. doi: 10.1002/jsp2.70154. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41459418 Free PMC article.

43

Regenerative Potential of Extracellular Vesicles on Intervertebral Disc Degeneration: What is the EV-idence?

Corraini D, Voskamp C, Wauben MHM, Tryfonidou MA. Corraini D, et al. JOR Spine. 2025 Dec 25;8(4):e70149. doi: 10.1002/jsp2.70149. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41459417 Free PMC article. Review.

44

Introduction to a Special Issue Describing an Observational Cohort of Adults With Chronic Low Back Pain.

Vo NV, Sowa GA. Vo NV, et al. JOR Spine. 2025 Dec 25;8(4):e70150. doi: 10.1002/jsp2.70150. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41459416 Free PMC article. No abstract available.

45

Understanding the Physiological Behavior of Disc Cells in an In Vitro Imitation of the Healthy and Degenerated Disc Niche.

Snuggs J, Basatvat S, Kanelis E, Binch A, Alexopoulos L, Tryfonidou MA, Le Maitre C. Snuggs J, et al. JOR Spine. 2025 Dec 22;8(4):e70153. doi: 10.1002/jsp2.70153. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41446036 Free PMC article.

46

Enhanced Quantitative Assessment of Lumbar Facet Joint Degeneration: Refining the Joint Degeneration Grading System With Grayscale Curve Fitting and Imaging Parameter.

Liu X, Sun M, He S, Zhang H, Li R, Shi J, Ma X. Liu X, et al. JOR Spine. 2025 Dec 15;8(4):e70151. doi: 10.1002/jsp2.70151. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41404333 Free PMC article.

47

Macrophage Subtypes Distinctly Impact Intervertebral Disc Inflammation and Extracellular Matrix Composition.

Lisiewski LE, Campos L, Jacobsen TD, Kim MKM, Chahine NO. Lisiewski LE, et al. JOR Spine. 2025 Dec 12;8(4):e70143. doi: 10.1002/jsp2.70143. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41394791 Free PMC article.

48

Comparative Finite Element Analysis of Denosumab and Bazedoxifene on Pedicle Screw Stability in Osteoporotic Spines.

Asada T, Tani S, Towatari T, Ishikawa M, Varnadore P, Kudo Y, Passias PG, Alman BA, Ishikawa K. Asada T, et al. JOR Spine. 2025 Dec 9;8(4):e70147. doi: 10.1002/jsp2.70147. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41376804 Free PMC article.

49

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis.

Melrose J. Melrose J. JOR Spine. 2025 Dec 9;8(4):e70145. doi: 10.1002/jsp2.70145. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41376803 Free PMC article. Review.

50

Development and Characterization of a Tunable PDMS Substrate Model for Investigating Elastic Properties and Mechanical Stretching in Intervertebral Disc Cells.

Hasler J, Lamoca M, Schimmelpfennig K, Zhang S, Hitzl W, Farajollahi S, Abhyankar VV, Lewis CL, Liu R, Wuertz-Kozak K. Hasler J, et al. JOR Spine. 2025 Dec 8;8(4):e70140. doi: 10.1002/jsp2.70140. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41368273 Free PMC article.

51

The Prognostic Significance of LINC00638 in Lumbar Disc Herniation and Its Effect on Senescence of Nucleus Pulposus Cells.

Wang Z, Liu J, Sun Y, Xu H, He W, Xu S, He X. Wang Z, et al. JOR Spine. 2025 Dec 5;8(4):e70138. doi: 10.1002/jsp2.70138. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41356258 Free PMC article.

52

Thoracolumbar Biomechanical Analysis of Lenke Type 1 Adolescent Idiopathic Scoliosis Across Roussouly Classifications.

Wu Z, Cheng H, He J, Dai X, He J, Liang D, Jiang X, Sun Y, She R, Lin Y, Liang Z, Wei W. Wu Z, et al. JOR Spine. 2025 Dec 1;8(4):e70148. doi: 10.1002/jsp2.70148. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41340893 Free PMC article.

53

Subject-Specific Musculoskeletal Modeling: The Future of Predicting and Preventing Proximal Junctional Failure in Adult Spinal Deformity.

Ashjaee N, Semonche A, Mikula AL, Kiss L, Anderson DE, Ignasiak D, Brown SHM, Street J, Fels S, Ward SR, Ames C, Oxland TR. Ashjaee N, et al. JOR Spine. 2025 Nov 30;8(4):e70142. doi: 10.1002/jsp2.70142. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41333840 Free PMC article.

54

Unveiling the Potential Mechanism of Asymmetric Fat Infiltration in Paraspinal Muscles of Adult Degenerative Scoliosis: The Role of the Hsa_circ_0006156/miR-122-5p/PPARA Regulatory Network.

Yang X, Guo L, Shu J. Yang X, et al. JOR Spine. 2025 Nov 30;8(4):e70146. doi: 10.1002/jsp2.70146. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41328264 Free PMC article.

55

An Ex Vivo Model of Intervertebral Disc Degeneration for Assessing Retention of Injectable Cell-Based Grafts.

Schmid R, Apte J, Schulze E, Sirek A, Schäfer G, Schäper J, Santini F, Negoias S, Barbero A, Martin I, Pelttari K, Schären S, Krupkova O, Mehrkens A. Schmid R, et al. JOR Spine. 2025 Nov 26;8(4):e70144. doi: 10.1002/jsp2.70144. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41311678 Free PMC article.

56

Evaluation of Lumbar Intervertebral Disc and Facet Joint Degeneration Using Histogram Analysis of T2 and T2* Values.

Liang X, Li Y, Hou B, Xiong Y, Morelli J, Liu WV, Li X. Liang X, et al. JOR Spine. 2025 Nov 26;8(4):e70141. doi: 10.1002/jsp2.70141. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41311677 Free PMC article.

57

Meta-Analysis of the Application Value of Metagenomic Next-Generation Sequencing Technology in the Diagnosis of Infectious Diseases of the Spine.

Cai X, Yi H, Chen K, Dai J, Yi J, Tu B, Wang Y, Li J, Zhuang J. Cai X, et al. JOR Spine. 2025 Nov 24;8(4):e70134. doi: 10.1002/jsp2.70134. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41306993 Free PMC article. Review.

58

Intracellular Detection of C. acnes and S. aureus in Non-Herniated Human Intervertebral Discs: Implications for Catabolic Signaling Pathways.

Nüesch A, Kanelis E, Alexopoulos LG, Gantenbein B, Lacey M, Le Maitre CL. Nüesch A, et al. JOR Spine. 2025 Nov 17;8(4):e70139. doi: 10.1002/jsp2.70139. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41257089 Free PMC article.

59

Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly.

Chen S, Li Z, Bigdon SF, Häckel S, Albers CE, Gantenbein B. Chen S, et al. JOR Spine. 2025 Nov 12;8(4):e70136. doi: 10.1002/jsp2.70136. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41235064 Free PMC article. Review.

60

Lovastatin-Loaded Nanoparticles in a Thermosensitive Chitosan Hydrogel as a Sustained Release System for Treating Intervertebral Disc Degeneration: In Vitro Cell Culture Study and In Vivo Evaluation Using a Needle-Puncture Induced Degeneration Model in Rat Caudal Discs.

Chen CW, Cheng YH, Yang KC, Huang CC, Hu MH, Sun YH, Wang JL, Yang SH. Chen CW, et al. JOR Spine. 2025 Nov 10;8(4):e70135. doi: 10.1002/jsp2.70135. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41230223 Free PMC article.

61

PIEZO1-Primary Cilia Axis Mediates Compressive Stress-Induced Growth Plate Degeneration and Ossification in Adolescent Idiopathic Scoliosis.

Chen F, Chen S, Peng F, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jing X, Dong J, Li T, Xi Y. Chen F, et al. JOR Spine. 2025 Nov 4;8(4):e70133. doi: 10.1002/jsp2.70133. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41194970 Free PMC article.

62

Beyond the Curve: The Muscle-Specific Asymmetries of Adolescent Idiopathic Scoliosis.

Duncombe P, Dick T, Ng PTT, Izatt MT, Labrom RD, Tucker K. Duncombe P, et al. JOR Spine. 2025 Nov 4;8(4):e70129. doi: 10.1002/jsp2.70129. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41194969 Free PMC article.

63

The Impact of the Ovine Annular Lesion Model on IVD Pathobiology and Utility of the Ovine Spinal Model in Patho-Anatomical Studies: A Historical Perspective.

Osti O, Little CB, Melrose J. Osti O, et al. JOR Spine. 2025 Nov 4;8(4):e70128. doi: 10.1002/jsp2.70128. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41194968 Free PMC article. Review.

64

Correction to "Patient-Reported Outcomes Among an Observational Cohort of Individuals With Chronic Low Back Pain".

[No authors listed] [No authors listed] JOR Spine. 2025 Oct 27;8(4):e70132. doi: 10.1002/jsp2.70132. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41158751 Free PMC article.

65

Lactate Metabolism in Intervertebral Disc Degeneration: Unveiling Novel Mechanisms Through Bioinformatics.

Sun H, He M, Pang J, Guo X, Huo Y, Ma J. Sun H, et al. JOR Spine. 2025 Oct 20;8(4):e70126. doi: 10.1002/jsp2.70126. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41122432 Free PMC article.

66

Injury Induces More Severe Biomechanical Changes in Middle-Aged and Geriatric Lumbar Spines in a Mouse Ex Vivo Model.

Bhadouria N, Tiao J, Baburova A, Jain C, Wang B, Demopoulos A, Nasser P, Hallmark AP, Shah V, Weiser JR, Vashishth D, Dahia CL, Lee Y, Hecht AC, Iatridis JC. Bhadouria N, et al. JOR Spine. 2025 Oct 19;8(4):e70127. doi: 10.1002/jsp2.70127. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41116840 Free PMC article.

67

Enzymatic Behavior of Condoliase in Porcine Nucleus Pulposus: Ex Vivo and In Vitro Assessment.

Watanabe I, Takeda K, Shirogane T. Watanabe I, et al. JOR Spine. 2025 Oct 19;8(4):e70131. doi: 10.1002/jsp2.70131. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41116839 Free PMC article.

68

Simulating Federated Learning to Enable Multi-Hospital Collaboration for Lumbopelvic Alignment Estimation.

Cina A, Tuci M, Pellisé F, Yilgor C, Alanay A, Pizones J, Kleinstück F, Obeid I, Charles YP, Richner-Wunderlin S, Galbusera F, Jutzeler CR; European Spine Study Group. Cina A, et al. JOR Spine. 2025 Oct 16;8(4):e70120. doi: 10.1002/jsp2.70120. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41112065 Free PMC article.

69

Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell-Based Regeneration.

Stirnimann A, Schlagenhof L, Gantenbein B, Ille F. Stirnimann A, et al. JOR Spine. 2025 Oct 16;8(4):e70130. doi: 10.1002/jsp2.70130. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41112064 Free PMC article. Review.

70

Reduced Shear Modulus and Altered Lamellar Morphology of the Outer Annulus Fibrosus in Painful Intervertebral Disc Degeneration Compared With Tissue From Non-Surgical Controls.

Bader TJ, Dhiman M, Vercio LL, Bouchard J, Nicholls F, Evaniew N, Jacobs B, Thomas KC, Salo P, Hart DA, Duncan NA, Swamy G. Bader TJ, et al. JOR Spine. 2025 Oct 8;8(4):e70123. doi: 10.1002/jsp2.70123. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41070231 Free PMC article.

71

High-Resolution 3-Dimensional Micro-CT Imaging of Intervertebral Discs Using a Novel Contrast Agent.

Buckles MM, Nur A, Warda NH, Moncher JC, Ansari MY. Buckles MM, et al. JOR Spine. 2025 Oct 7;8(4):e70125. doi: 10.1002/jsp2.70125. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41064477 Free PMC article.

72

Age and Spinal Level as Predictors of Lumbar Disc Degeneration in Humans and Mice: A Comparative Analysis.

Mehta R, Mohanty S, Hallmark AP, Shah V, Ross T, Bogner EA, Pannu TS, Bannwarth M, Virk S, Iyer S, Farmer JC, Huang RC, Lebl DR, Rawlins BA, Sandhu HS, Kim HJ, Cunningham ME, Qureshi S, Albert TJ, Dahia CL. Mehta R, et al. JOR Spine. 2025 Oct 7;8(4):e70122. doi: 10.1002/jsp2.70122. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41064476 Free PMC article.

73

Automated Computational Pathology to Assess Degenerative Disc Histology.

Bell RD, Reddick EC, Lillyman DJ, Lee FS, Wachs RA. Bell RD, et al. JOR Spine. 2025 Oct 1;8(4):e70119. doi: 10.1002/jsp2.70119. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41041619 Free PMC article.

74

Mobile Health (mHealth) for Chronic Low Back Pain Assessment: Design, Development, and Usability Evaluation.

Alfikri ZF, Johnson ME, Dicianno BE, Greco CM, Parmanto B, Piva SR, Roos RE, Saptono A, Sowa GA, Zhou L, Bell KM. Alfikri ZF, et al. JOR Spine. 2025 Oct 1;8(4):e70118. doi: 10.1002/jsp2.70118. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41041618 Free PMC article.

75

Single-Side Iatrogenic Pedicle Injury May Trigger an Increased Risk of Contralateral Screw Loosening: An In Silico Study.

Yang J, Chen J, Wang G, Jia L, Zhou Y, Li J. Yang J, et al. JOR Spine. 2025 Oct 1;8(4):e70124. doi: 10.1002/jsp2.70124. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41041617 Free PMC article.

76

Vertebral Growth Modulation Through Periosteal Resection and Fixed Length Deformity Overcorrection: Computational and In Vivo Pilot Study.

Halanski MA, Jeffers C, Abubakr Y, Zhou M, Kokinos B, Twedt M, Bennett D, Hamman S, Crenshaw T, O'Connell GD, Haider H. Halanski MA, et al. JOR Spine. 2025 Oct 1;8(4):e70121. doi: 10.1002/jsp2.70121. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41041616 Free PMC article.

77

Lumbopelvic Kinematics During Functional Tasks in a Chronic Low Back Pain Observational Cohort.

Bell KM, Roos RE, Alfikri Z, Anderst W, Bailes A, Clark WW, Cook HA, Darwin J, Johnson M, McKernan GP, Murati S, Parmanto B, Vo NV, Zhou L, Sowa GA. Bell KM, et al. JOR Spine. 2025 Oct 1;8(4):e70117. doi: 10.1002/jsp2.70117. eCollection 2025 Dec. JOR Spine. 2025. PMID: 41041615 Free PMC article.

78

A Comparison of Five Animal Models for Acute Intervertebral Disc Herniation Research.

Slater TD, Gagliostri B, Kibble MJ, Tümer NS, Cripton PA, Newell N. Slater TD, et al. JOR Spine. 2025 Sep 24;8(3):e70116. doi: 10.1002/jsp2.70116. eCollection 2025 Sep. JOR Spine. 2025. PMID: 41000178 Free PMC article.

79

Exploring the Biopsychosocial Impact of Chronic Low Back Pain in Workers Through Artificial Intelligence-Driven Phenotyping.

Giaccone P, de Rinaldis E, D'Antoni F, Russo F, Ambrosio L, Petrucci G, Merone M, Pecchia L, Iavicoli S, Vadalà G, Papalia R, Denaro V. Giaccone P, et al. JOR Spine. 2025 Sep 17;8(3):e70110. doi: 10.1002/jsp2.70110. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40969914 Free PMC article.

80

Plasma Pro- and Anti-Inflammatory Cytokines in an Observational Chronic Low Back Pain Cohort.

Enrico VT, Anderst W, Bell KM, Coelho JP, Darwin J, Delitto A, Greco CM, Lee JY, McKernan GP, Patterson CG, Piva SR, Schneider MJ, Wilcox L, Vo NV, Sowa GA. Enrico VT, et al. JOR Spine. 2025 Sep 16;8(3):e70095. doi: 10.1002/jsp2.70095. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40964420 Free PMC article.

81

MRI-Based Grading Systems for Assessing Lumbar Disc Degeneration: A Scoping Review.

Esposito D, Brown B, Hancock MJ, King SSG, Searant IGT, Jenkins H. Esposito D, et al. JOR Spine. 2025 Sep 15;8(3):e70113. doi: 10.1002/jsp2.70113. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40959741 Free PMC article. Review.

82

Comprehensive Evaluation of Facet Joints Osteoarthritis Radiological Features on Lumbar CT: A Multitask Deep Learning Approach.

Wang Y, Chen Z, Huang J, He Q, Leng D, Yang L, Feng J, Lu J, Chen T, Feng Q, Su Z, Lu H, Lu S. Wang Y, et al. JOR Spine. 2025 Sep 11;8(3):e70115. doi: 10.1002/jsp2.70115. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40949054 Free PMC article.

83

Validation of a Coordinate Optimization Approach for Assessment of In Vivo Intervertebral Kinematics in Patients With Adult Spinal Deformity and Healthy Older Adults.

Peeters B, Keko M, Scheys L, Anderson DE. Peeters B, et al. JOR Spine. 2025 Sep 10;8(3):e70108. doi: 10.1002/jsp2.70108. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40937362 Free PMC article.

84

Advanced Glycation End Products Induce Caudal Disc Degeneration in Ovariectomized Female Rats.

Liang X, Li Z, Ren P, Gao Z, Tian X, Zhang W, Cooper-White J, Liu G, Yang S. Liang X, et al. JOR Spine. 2025 Sep 9;8(3):e70114. doi: 10.1002/jsp2.70114. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40933187 Free PMC article.

85

A Cross-Tissue Transcriptome-Wide Association Study Identified Susceptibility Genes for Intervertebral Disc Degeneration.

Zhang L, Zhao W, Yang H, Deng T, Li Y. Zhang L, et al. JOR Spine. 2025 Sep 7;8(3):e70109. doi: 10.1002/jsp2.70109. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40922807 Free PMC article.

86

TRIM25-Mediated Ubiquitination and Degradation of SOX8 Promotes Ligament Fibroblast Osteogenic Differentiation and Regulates OPLL Progression by Inhibiting OSR2 Transcription.

Wang Z, Tang Y, Gu C, Lu M, Wei Z, Zhou Q, Zhou S, Chen X. Wang Z, et al. JOR Spine. 2025 Sep 5;8(3):e70112. doi: 10.1002/jsp2.70112. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40918640 Free PMC article.

87

Wharton's Jelly Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Intervertebral Disc Degeneration Under Inflammatory Stress in an In Vitro 3D Culture System.

Tilotta V, Vadalà G, Di Giacomo G, Ambrosio L, Cicione C, Russo F, Darinskas A, Papalia R, Denaro V. Tilotta V, et al. JOR Spine. 2025 Aug 20;8(3):e70106. doi: 10.1002/jsp2.70106. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40842947 Free PMC article.

88

Quantitative Sensory Testing in an Observational Cohort of Adults With Chronic Low Back Pain.

Schneider MJ, Greco CM, Acevedo AM, Bell KM, Darwin J, Delitto A, Dodds NE, Jakicic JM, McKernan GP, Patterson CG, Pilkonis PA, Piva SR, Sowa GA, Vo NV, Yu L, Wasan AD. Schneider MJ, et al. JOR Spine. 2025 Aug 19;8(3):e70103. doi: 10.1002/jsp2.70103. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40837129 Free PMC article.

89

Biological Sex Is Under-Reported in Cartilage-Related Preclinical Research: A Cross-Sectional Analysis.

Zuncheddu D, Buedo P, Stoddart MJ, Creemers LB, Grad S, Waligora M. Zuncheddu D, et al. JOR Spine. 2025 Aug 18;8(3):e70104. doi: 10.1002/jsp2.70104. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40831693 Free PMC article.

90

A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain.

Melrose J, Sima S, Chopra N, Diwan A, Gu Z. Melrose J, et al. JOR Spine. 2025 Aug 15;8(3):e70107. doi: 10.1002/jsp2.70107. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40821360 Free PMC article. Review.

91

Relationship Between Quantitative MRI and Radiological, Histological, and Biochemical Measures of Intervertebral Disc Health in Client-Owned, Nonchondrodystrophic-Breed Dogs.

Falck AL, Buko EO, Chase KL, Pendleton D, McDermott K, Kim O, Parvaze SP, Armstrong AR, Arnold SA, Bradley EW, Ellingson AM, Ober CP, Rendahl A, Johnson CP. Falck AL, et al. JOR Spine. 2025 Aug 13;8(3):e70105. doi: 10.1002/jsp2.70105. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40821359 Free PMC article.

92

Patient-Reported Outcomes Among an Observational Cohort of Individuals With Chronic Low Back Pain.

Greco CM, Dodds NE, Acevedo AM, Anderst W, Bell KM, Darwin J, Delitto A, Jakicic JM, McKernan GP, Patterson CG, Pilkonis PA, Piva SR, Schneider MJ, Vo NV, Wasan AD, Yu L, Sowa GA. Greco CM, et al. JOR Spine. 2025 Aug 13;8(3):e70097. doi: 10.1002/jsp2.70097. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40809737 Free PMC article.

93

Comments on "Exploring the Therapeutic Potential of Puerarin on Intervertebral Disc Degeneration by Regulating Apoptosis of Nucleus Pulposus Cells".

Jin J, Liu M, Guo J, Sun H. Jin J, et al. JOR Spine. 2025 Aug 12;8(3):e70099. doi: 10.1002/jsp2.70099. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40799633 Free PMC article. No abstract available.

94

Feasibility of Physical Exam and Performance-Based Tests in Individuals With Chronic Low Back Pain: A Descriptive Study.

Piva SR, Alfikri Z, Anderst W, Bell KM, Carlesso C, Darwin J, Delitto A, Greco CM, Johnson ME, McKernan GP, McLoughlin R, Patterson CG, Roos RE, Schneider MJ, Smith C, Sowa GA, Vo NV, Zhou L. Piva SR, et al. JOR Spine. 2025 Aug 12;8(3):e70096. doi: 10.1002/jsp2.70096. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40799632 Free PMC article.

95

Central Pattern Generators in Spinal Cord Injury: Mechanisms, Modulation, and Therapeutic Strategies for Motor Recovery.

Su H, Jing L, Lv D, Huan Z, Xu W. Su H, et al. JOR Spine. 2025 Aug 11;8(3):e70100. doi: 10.1002/jsp2.70100. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40791879 Free PMC article. Review.

96

Gait Analysis During Paralysis Recovery in a Rat Incomplete Spinal Cord Injury Model.

Toyota M, Masuda S, Nohara D, Oba S, Tomomitsu M, Nagai-Tanima M, Aoyama T. Toyota M, et al. JOR Spine. 2025 Aug 6;8(3):e70102. doi: 10.1002/jsp2.70102. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40771563 Free PMC article.

97

Spatial and Diurnal Variations in Sodium Content Within Intervertebral Disc Tissue.

Marshall JT, Lutton AD, Grinstaff MW, Olesik JW, Walter BA. Marshall JT, et al. JOR Spine. 2025 Aug 5;8(3):e70079. doi: 10.1002/jsp2.70079. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40766839 Free PMC article.

98

Comparative Performance of Calcium Phosphate Grafts and Iliac Crest Autograft in Posterolateral Spinal Fusion in Rabbits.

Walsh WR, Oliver RA, Pelletier MH, Wang T, Christou C, Walsh ER, Page JM, Davis CT, Williams GM. Walsh WR, et al. JOR Spine. 2025 Jul 30;8(3):e70101. doi: 10.1002/jsp2.70101. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40741218 Free PMC article.

99

Development and Validation of a Machine Learning-Based Online Prognostic Model for Cervical Spondylosis Patients After Anterior Cervical Discectomy and Fusion: A Multicenter Study.

Feng S, Huang S, Zhou Z, Zhang B, Huang C, Chen T, Zhou C, Wu S, Zhu J, Chen J, Xue J, Zhan X, Liu C. Feng S, et al. JOR Spine. 2025 Jul 28;8(3):e70090. doi: 10.1002/jsp2.70090. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40727551 Free PMC article.

100

Animal Models of Disc Degeneration Using Puncture Injury: A 20 Year Perspective.

Jain C, Huang JJ, Lee Y, Chaudhary S, Hecht AC, Lai A, Masuda K, Kang J, Iatridis JC. Jain C, et al. JOR Spine. 2025 Jul 28;8(3):e70093. doi: 10.1002/jsp2.70093. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40727550 Free PMC article. Review.

101

Evaluation of a Force-Control Experimental Method to Perform Unconstrained Load-Induced Subsidence Testing of Spinal Interbody Implants.

Benais R, Barina R, McLachlin S. Benais R, et al. JOR Spine. 2025 Jul 25;8(3):e70087. doi: 10.1002/jsp2.70087. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40718821 Free PMC article.

102

Effect of Vertebral Body Tether Tensioning on Vertebral Body Growth Modulation.

Jackson TJ, Louer C, El-Hawary R, Hurry J, Nian H, Farnsworth C, Bartley CE, Bryan TP, Kelly MP, Newton PO, Parent S; Pediatric Spine Study Group; Upasani VV. Jackson TJ, et al. JOR Spine. 2025 Jul 24;8(3):e70098. doi: 10.1002/jsp2.70098. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40708692 Free PMC article.

103

Short-Term Dynamic Unloading of Bovine Tail Discs in Culture Partially Mitigates Induced Degeneration After One-Strike Trigger.

Soubrier A, Kasper H, Vonlanthen N, Jonkers I, Grad S. Soubrier A, et al. JOR Spine. 2025 Jul 16;8(3):e70092. doi: 10.1002/jsp2.70092. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40671965 Free PMC article.

104

Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain.

Heimann MK, Tang SN, Gunsch G, Kuchynsky K, Klamer B, Zhao F, Co M, Pietrzak M, Richards J, Klausner J, Smith A, Cimney K, McBride-Gagyi S, Youngblood B, Corps K, Askwith C, Walter BA, Moore SA, Purmessur D. Heimann MK, et al. JOR Spine. 2025 Jul 14;8(3):e70082. doi: 10.1002/jsp2.70082. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40662113 Free PMC article.

105

Demographic and Biomedical Characteristics of an Observational Cohort With Chronic Low Back Pain: A Descriptive Analysis.

Piva SR, Smith C, Anderst W, Bell KM, Darwin J, Delitto A, Flynn C, Greco CM, McKernan GP, Schneider MJ, Sowa GA, Sundaram M, Vo NV, Zhou L, Patterson CG. Piva SR, et al. JOR Spine. 2025 Jul 14;8(3):e70094. doi: 10.1002/jsp2.70094. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40662112 Free PMC article.

106

Impact of Habitual Flexion on Bone Formation After Spinal Fusion Surgery: An In Silico Study.

Ananth Swaminathan S, Taheri N, Becker L, Pumberger M, Schmidt H, Checa S. Ananth Swaminathan S, et al. JOR Spine. 2025 Jul 14;8(3):e70075. doi: 10.1002/jsp2.70075. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40662111 Free PMC article.

107

Ultrafine-Grained Materials With Antibacterial Properties: A Novel Approach to Reducing Spinal Implant-Associated Infections.

Nishizawa M, Hu D, Serhan H, Saleh B, Marcucio RS, Morioka K. Nishizawa M, et al. JOR Spine. 2025 Jun 30;8(3):e70091. doi: 10.1002/jsp2.70091. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40606199 Free PMC article.

108

Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi-Axial Perspective of Mechanical, Immune, and Metabolic Pathways.

Yang Y, Li H, Zuo J, Lei F. Yang Y, et al. JOR Spine. 2025 Jul 2;8(3):e70089. doi: 10.1002/jsp2.70089. eCollection 2025 Sep. JOR Spine. 2025. PMID: 40606198 Free PMC article. Review.

109

The Helical Compliance Vector: Utility for Quantifying Spinal Mechanics.

MacEwen MR, Abbott RE, Barocas VH, Ellingson AM. MacEwen MR, et al. JOR Spine. 2025 Jun 19;8(2):e70088. doi: 10.1002/jsp2.70088. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40538464 Free PMC article.

110

Human Placental Extract as a Promising Epidural Therapy for Lumbar Spinal Stenosis: Enhancing Axonal Plasticity and Mitigating Pain and Inflammation in a Rat Model.

Hong JY, Kim H, Jeon WJ, Yeo C, Lee J, Kim H, Lee YJ, Ha IH. Hong JY, et al. JOR Spine. 2025 Jun 17;8(2):e70085. doi: 10.1002/jsp2.70085. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40535717 Free PMC article.

111

Complex In Vivo Motion of the Bovine Tail Provides Unique Insights Into Intervertebral Disc Adaptation.

Michalek AJ, Wood IM, Gonzalez Carranza D, Ferlito L. Michalek AJ, et al. JOR Spine. 2025 Jun 17;8(2):e70084. doi: 10.1002/jsp2.70084. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40529400 Free PMC article.

112

Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc.

Warren JP, Dixon AR, Culbert MP, Khan A, Mengoni M, Wilcox RK. Warren JP, et al. JOR Spine. 2025 Jun 10;8(2):e70081. doi: 10.1002/jsp2.70081. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40496969 Free PMC article.

113

The Role of Adipokines in Spinal Disease: A Narrative Review.

McDonnell JM, Darwish S, Butler JS, Buckley CT. McDonnell JM, et al. JOR Spine. 2025 Jun 3;8(2):e70083. doi: 10.1002/jsp2.70083. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40470308 Free PMC article. Review.

114

Intradiscal Mesenchymal Stromal Cell Therapy for the Treatment of Low Back Pain Due to Moderate-to-Advanced Multilevel Disc Degeneration: A Preliminary Report of a Double-Blind, Phase IIB Randomized Clinical Trial (DREAM Study).

Vadalà G, Russo F, Lavazza C, Petrucci G, Ambrosio L, Budelli S, Montelatici E, Di Giacomo G, Cicione C, Tilotta V, Papalia GF, Pileri M, Bruno A, La Rosa S, Carrino E, Faiella E, Carassiti M, Lazzari L, Papalia R, Denaro V. Vadalà G, et al. JOR Spine. 2025 Jun 2;8(2):e70086. doi: 10.1002/jsp2.70086. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40462867 Free PMC article.

115

Crosstalk Between Ferroptosis and Cuproptosis in Intervertebral Disc Degeneration: Mechanisms, Therapeutic Targets, and Future Directions.

Li Z, Wang L, Wu X, Huang R, Yuan Y. Li Z, et al. JOR Spine. 2025 May 28;8(2):e70080. doi: 10.1002/jsp2.70080. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40444212 Free PMC article. Review.

116

Causal Relationship Between Gut Microbiota, Blood Metabolites, and Intervertebral Disc Degeneration: A Two-Step, Two-Sample Bidirectional Mendelian Randomization Study.

Zheng YP, Yang DL, Wang LY, Zhu XZ, Li XC, Miao JH, Xu YS. Zheng YP, et al. JOR Spine. 2025 May 29;8(2):e70078. doi: 10.1002/jsp2.70078. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40444211 Free PMC article.

117

In Vivo Measurements Reveal Increased Nucleus Pulposus Lactate and Oxygen Concentrations in a Goat Model of Intervertebral Disc Degeneration.

Rajagopal K, Schaer TP, Meadows KD, Boyes M, Hilliard R, O'Donnell JC, Dodge GR, Petrov D, Elliott DM, Mauck RL, Smith LJ, Malhotra NR. Rajagopal K, et al. JOR Spine. 2025 May 27;8(2):e70076. doi: 10.1002/jsp2.70076. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40438632 Free PMC article.

118

TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model.

Jacobsen TD, Yiantsos SO, Gansau J, Meyers J, Laudier D, Iatridis JC. Jacobsen TD, et al. JOR Spine. 2025 May 19;8(2):e70070. doi: 10.1002/jsp2.70070. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40391206 Free PMC article.

119

In Vitro Validation of Pulsed Electromagnetic Field (PEMF) as an Effective Countermeasure Against Inflammatory-Mediated Intervertebral Disc Degeneration.

Guarnaccia L, Begani L, Pileggi S, Pluderi M, Borsa S, Fanizzi C, Rizzaro MD, Fiore G, Fontana L, Campanella R, Cordiglieri C, Gaudino C, Alotta GA, Miozzo M, Garzia E, Barilla E, Fassina L, Riboni L, Locatelli M, Marfia G, Navone SE. Guarnaccia L, et al. JOR Spine. 2025 May 19;8(2):e70077. doi: 10.1002/jsp2.70077. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40391205 Free PMC article.

120

An Extracellular Matrix Hydrogel Restores Disc Volume and Alleviates Axial Hypersensitivity in a Rat Model of Disc-Associated Pain.

Lillyman DJ, Reddick EC, Ney KE, Caparaso SM, Wachs RA. Lillyman DJ, et al. JOR Spine. 2025 May 15;8(2):e70073. doi: 10.1002/jsp2.70073. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40386495 Free PMC article.

121

The Role of Sex Hormones in Cartilaginous Tissues: A Scoping Review.

Hutchinson JL, Hutchinson AJ, Feng J, Séguin CA. Hutchinson JL, et al. JOR Spine. 2025 May 15;8(2):e70072. doi: 10.1002/jsp2.70072. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40386494 Free PMC article. Review.

122

Correction to "Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions".

[No authors listed] [No authors listed] JOR Spine. 2025 May 15;8(2):e70074. doi: 10.1002/jsp2.70074. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40376566 Free PMC article.

123

Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear-Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes.

Pinto SM, Cheung JPY, Samartzis D, Karppinen J, Zheng YP, Pang MYC, Fortin M, Wong AYL. Pinto SM, et al. JOR Spine. 2025 May 15;8(2):e70071. doi: 10.1002/jsp2.70071. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40376565 Free PMC article.

124

Intervertebral Lumbar Spine Kinematics in Chronic Low Back Pain Patients Measured Using Biplane Radiography.

Anderst W, Kim CJ, Bell KM, Gale T, Gray C, Greco CM, LeVasseur C, McKernan G, Megherhi S, Patterson CG, Piva SR, Pellegrini C, Schneider MJ, Shoemaker J, Smith P, Vo NV, Sowa GA. Anderst W, et al. JOR Spine. 2025 May 14;8(2):e70069. doi: 10.1002/jsp2.70069. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40371271 Free PMC article.

125

Mechanisms and Therapeutic Strategies of Macrophage Polarization in Intervertebral Disc Degeneration.

Zheng K, Wang S, Deng M, Luo Y, Li W, Zeng L, Wang Y. Zheng K, et al. JOR Spine. 2025 May 14;8(2):e70065. doi: 10.1002/jsp2.70065. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40371270 Free PMC article. Review.

126

Human Disc Degeneration Is Accompanied by a Loss of Anterior Annulus Fibrosus Interlamellar Matrix Integrity as Assessed by Peel Tests.

Dhiman MS, Salaam MA, Bader TJ, Nicholls F, Jacobs WB, Thomas KC, Bouchard J, Salo PT, Hart DA, Swamy G, Duncan NA. Dhiman MS, et al. JOR Spine. 2025 May 14;8(2):e70067. doi: 10.1002/jsp2.70067. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40371269 Free PMC article.

127

Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc.

Zhang Y, Xu J, Zhou Z, Richards RG, Alini M, Grad S, Li Z. Zhang Y, et al. JOR Spine. 2025 May 7;8(2):e70068. doi: 10.1002/jsp2.70068. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40337077 Free PMC article.

128

Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress-Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy.

Dong Y, Li C, Tu S, Liu M, Lv K, Duan L, Zhang F, Cai H, Chen X, Zhang W. Dong Y, et al. JOR Spine. 2025 Apr 10;8(2):e70058. doi: 10.1002/jsp2.70058. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40309337 Free PMC article.

129

Physiological and Anthropometric Factors Associated With Spine Loading Estimates From Imaging-Based Subject-Specific Musculoskeletal Models.

Allaire BT, Johannesdottir F, Bouxsein ML, Anderson DE. Allaire BT, et al. JOR Spine. 2025 Apr 11;8(2):e70059. doi: 10.1002/jsp2.70059. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40225046 Free PMC article.

130

Identification and Validation of Circadian Rhythm-Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning.

Zhang Y, Chen L, Yang S, Dai R, Sun H, Zhang L. Zhang Y, et al. JOR Spine. 2025 Apr 13;8(2):e70066. doi: 10.1002/jsp2.70066. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40225045 Free PMC article.

131

Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One-Sample Mendelian Randomization Study.

Naeini MK, Freidin MB, Smith IG, Ward S, Williams FMK. Naeini MK, et al. JOR Spine. 2025 Apr 8;8(2):e70063. doi: 10.1002/jsp2.70063. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40201537 Free PMC article.

132

Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.

Wang W, Jiang C, Chen JH, Chen YL, Zhang ZW, Yang ZC, Li J, Li XC. Wang W, et al. JOR Spine. 2025 Apr 8;8(2):e70061. doi: 10.1002/jsp2.70061. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40201536 Free PMC article.

133

Molecular Subtypes and Immune Microenvironment Characterization of the Annulus Fibrosus in Intervertebral Disc Degeneration: Insights From Translation Factor-Related Gene Analysis.

Zheng S, Zhao X, Wu H, Cuan X, Cheng X, He D. Zheng S, et al. JOR Spine. 2025 Apr 7;8(2):e70064. doi: 10.1002/jsp2.70064. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40196451 Free PMC article.

134

Phosphatidylcholine Ameliorates Palmitic Acid-Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration.

Tu S, Dong Y, Li C, Jiang M, Duan L, Zhang W, Chen X. Tu S, et al. JOR Spine. 2025 Mar 31;8(2):e70062. doi: 10.1002/jsp2.70062. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40171442 Free PMC article.

135

Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique.

Jiang C, Song C, Chen C, Shen B, Yang L, Zhang C, Liu F, Wu X, Chen F. Jiang C, et al. JOR Spine. 2025 Mar 31;8(2):e70055. doi: 10.1002/jsp2.70055. eCollection 2025 Jun. JOR Spine. 2025. PMID: 40171441 Free PMC article.

136

The Significance of MAPK Signaling Pathway in the Diagnosis and Subtype Classification of Intervertebral Disc Degeneration.

Liu Y, Chen X, Chen J, Song C, Wei Z, Liu Z, Liu F. Liu Y, et al. JOR Spine. 2025 Mar 24;8(1):e70060. doi: 10.1002/jsp2.70060. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40134951 Free PMC article.

137

Transcriptome Data Combined With Mendelian Randomization Analysis Identifies Key Genes Associated With Mitochondria and Programmed Cell Death in Intervertebral Disc Degeneration.

Nie H, Hu X, Wang J, Wang J, Yu X, Li J. Nie H, et al. JOR Spine. 2025 Mar 24;8(1):e70057. doi: 10.1002/jsp2.70057. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40130183 Free PMC article.

138

Application and Validation of Semiautomatic Quantification of Immunohistochemically Stained Sections for Low Cellular Tissue Such as Intervertebral Disc Using QuPath.

Nüesch A, Ferri MP, Le Maitre CL. Nüesch A, et al. JOR Spine. 2025 Mar 6;8(1):e70054. doi: 10.1002/jsp2.70054. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40061888 Free PMC article.

139

The Significance of Cellular Senescence Hub Genes in the Diagnosis and Subtype Classification of a Comprehensive Database of Gene Expression in Intervertebral Disc Degeneration.

Liu F, Gao S, Yin J, Song C, Mei Y, Wang Z, Liu Z. Liu F, et al. JOR Spine. 2025 Mar 6;8(1):e70050. doi: 10.1002/jsp2.70050. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40061887 Free PMC article.

140

DeVa (Decay Variance): A Novel Score Calculated via Postprocessing the Changes in Signal Intensity of an Intervertebral Disc in a T2* Multi-Echo Magnetic Resonance Image Can Quantify Painful and Degenerate Lumbar Vertebral Discs.

Sima S, Sial A, Sharma S, Ananthakrishnan D, Kuan J, Diwan A. Sima S, et al. JOR Spine. 2025 Mar 6;8(1):e70056. doi: 10.1002/jsp2.70056. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40061886 Free PMC article.

141

Range of Motion and Neutral Zone of All Human Spinal Motion Segments: A Data Collection of 30 Years of In Vitro Experiments Performed Under Standardized Testing Conditions.

Wilke HJ, Kienle A, Werner K, Liebsch C. Wilke HJ, et al. JOR Spine. 2025 Mar 5;8(1):e70052. doi: 10.1002/jsp2.70052. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40046266 Free PMC article.

142

Ruxolitinib Delays Nucleus Pulposus Cell Senescence in Rat Intervertebral Discs.

Hao H, Liang W, Zhang S, Cai X, Yakefu A, Gao S, Xun C, Xu T, Cao R, Sheng W. Hao H, et al. JOR Spine. 2025 Mar 5;8(1):e70044. doi: 10.1002/jsp2.70044. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40046265 Free PMC article.

143

Mechanism of Intervertebral Disc Degeneration via the β-Catenin/CCL2 Pathway in Sox9 Conditional Knockout Mice.

Aboushaala K, Chee A, Ko F, Alkhudari J, Sumughan S, An HS, Samartzis D, Oh CD. Aboushaala K, et al. JOR Spine. 2025 Feb 26;8(1):e70053. doi: 10.1002/jsp2.70053. eCollection 2025 Mar. JOR Spine. 2025. PMID: 40012719 Free PMC article.

144

Gene Expression Changes Precede Elevated Mechanical Sensitivity in the Mouse Intervertebral Disc Injury Model.

Tian Z, Chen K, Shofer FS, Ciesielski B, Wang H, O'Brien WT, Qin L, Zhang Y. Tian Z, et al. JOR Spine. 2025 Feb 23;8(1):e70049. doi: 10.1002/jsp2.70049. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39989623 Free PMC article.

145

Parallel Networks to Predict TIMP and Protease Cell Activity of Nucleus Pulposus Cells Exposed and Not Exposed to Pro-Inflammatory Cytokines.

Baumgartner L, Witta S, Noailly J. Baumgartner L, et al. JOR Spine. 2025 Feb 20;8(1):e70051. doi: 10.1002/jsp2.70051. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39981424 Free PMC article.

146

Do we know more about the mechanobiology of the intervertebral disc in space than on Earth?

Holsgrove TP, Ebisch I, Lazaro-Pacheco D. Holsgrove TP, et al. JOR Spine. 2025 Feb 18;8(1):e70024. doi: 10.1002/jsp2.70024. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39968355 Free PMC article.

147

Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc.

Matsuo T, Takeoka Y, Yurube T, Tsujimoto T, Kanda Y, Miyazaki K, Ohnishi H, Ryu M, Kumagai N, Kuroshima K, Hiranaka Y, Kuroda R, Kakutani K. Matsuo T, et al. JOR Spine. 2025 Feb 17;8(1):e70046. doi: 10.1002/jsp2.70046. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39963549 Free PMC article.

148

Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL-4 and IL-10 in Intervertebral Disc Pathophysiology.

Bermudez-Lekerika P, Tseranidou S, Kanelis E, Nüesch A, Crump KB, Alexopoulos LG, Wuertz-Kozak K, Noailly J, Le Maitre CL, Gantenbein B. Bermudez-Lekerika P, et al. JOR Spine. 2025 Feb 10;8(1):e70048. doi: 10.1002/jsp2.70048. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39931581 Free PMC article.

149

Annulus Fibrosus Repair via Interpenetration of a Non-Woven Scaffold Supports Tissue Integration and Prevents Re-Herniation.

Ongini ED, Abdullah M, Engiles JB, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand SE. Ongini ED, et al. JOR Spine. 2025 Feb 6;8(1):e70045. doi: 10.1002/jsp2.70045. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39925750 Free PMC article.

150

The Cross-Sectional Areas and Anterior-Posterior Balance of the Cervical Paraspinal Muscles in Dropped Head Syndrome and Cervical Spondylotic Myelopathy: A Propensity Score-Matched Analysis.

Sono T, Ijiri K, Kakehi K, Masuda S, Shimizu T, Murata K, Matsuda S, Otsuki B. Sono T, et al. JOR Spine. 2025 Jan 30;8(1):e70047. doi: 10.1002/jsp2.70047. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39896130 Free PMC article.

151

Variations in ECM Topography, Fiber Alignment, Mechanical Stiffness, and Cellular Composition Between Ventral and Dorsal Ligamentum Flavum Layers: Insights Into Hypertrophy Pathogenesis.

Tu TY, Hsu YC, Yang CE, Shyong YJ, Kuo CH, Liu YF, Shih SS, Lin CL. Tu TY, et al. JOR Spine. 2025 Jan 30;8(1):e70033. doi: 10.1002/jsp2.70033. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39886656 Free PMC article.

152

Explorative Study of Modulatory Effects of Notochordal Cell-Derived Extracellular Vesicles on the IL-1β-Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants.

van Maanen JC, Bach FC, Snuggs JW, Ito K, Wauben MHM, Le Maitre CL, Tryfonidou MA. van Maanen JC, et al. JOR Spine. 2025 Jan 29;8(1):e70043. doi: 10.1002/jsp2.70043. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39881783 Free PMC article.

153

E74-like ETS transcription factor 3 expression and regulation in human intervertebral disc.

González-Rodríguez M, Ait Eldjoudi D, Cordero-Barreal A, Farrag M, Varela-García M, Ruiz-Fernández C, Torrijos-Pulpón C, Lago F, García-Caballero L, Farrag Y, Conde-Aranda J, Pino J, Gualillo O. González-Rodríguez M, et al. JOR Spine. 2025 Jan 28;8(1):e70016. doi: 10.1002/jsp2.70016. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39877798 Free PMC article.

154

Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions.

Li W, Tu J, Zheng J, Das A, Yan Q, Jiang X, Ding W, Bai X, Lai K, Yang S, Yang C, Zou J, Diwan AD, Zheng Z. Li W, et al. JOR Spine. 2025 Jan 27;8(1):e70042. doi: 10.1002/jsp2.70042. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39877797 Free PMC article.

155

Contemporary clinical perspectives on chronic low back pain: The biology, mechanics, etc. underpinning clinical and radiological evaluation.

Sima S, Diwan A. Sima S, et al. JOR Spine. 2025 Jan 23;8(1):e70021. doi: 10.1002/jsp2.70021. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39867670 Free PMC article.

156

Is There a Positive or Negative Correlation Between Cervical Vertebral Bone Quality and Intervertebral Disc Degeneration by Pfirrmann Grading.

Qiu Z, Chen S, Feng N, Li W, Ma Y, Zhou S, Jiang G, Zhou Y, Yu X, Xiong Y. Qiu Z, et al. JOR Spine. 2025 Jan 23;8(1):e70038. doi: 10.1002/jsp2.70038. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39850653 Free PMC article.

157

Intervertebral Disc Degeneration Mediates the Causal Effect of Genetically Predicted Diffuse Idiopathic Skeletal Hyperostosis on Spinal Stenosis: Evidence From a Mendelian Randomization Study.

Shen Y, Jiang Y, Jiang R, Huang Y, Zhan S, Wang Y, Tang X, Yi P. Shen Y, et al. JOR Spine. 2025 Jan 20;8(1):e70041. doi: 10.1002/jsp2.70041. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39838974 Free PMC article.

158

Low-Frequency Cyclic Stretch Upregulates the Expression of Nuclear Factor Erythroid 2-Related Factor 2 in Human Nucleus Pulposus Cells to Inhibit the Resistin-Induced Interleukin-20 Expression.

Yen CK, Pan HY, Chang HI, Lu YC, Jeng YR, Chen CN, Huang KY. Yen CK, et al. JOR Spine. 2025 Jan 20;8(1):e70040. doi: 10.1002/jsp2.70040. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39838973 Free PMC article.

159

Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal MRI and Micro-CT in a Rat Model of Chronic Kidney Disease.

Huang GS, Chiang SW, Peng YJ, Yeh SH, Hsu YJ, Chou YC, Chang HH, Lee HS, Liu YC, Wang CY. Huang GS, et al. JOR Spine. 2025 Jan 20;8(1):e70039. doi: 10.1002/jsp2.70039. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39838972 Free PMC article.

160

Unilateral Lumbo-Pelvic Fixation for Denis Type I Unilateral Sacral Fracture: A Finite Element Analysis.

Yang J, Böker KO, Li X, Zhou X, Lehmann W. Yang J, et al. JOR Spine. 2025 Jan 20;8(1):e70022. doi: 10.1002/jsp2.70022. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39835271 Free PMC article.

161

Single-Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions.

Song C, Wu X, Chen C, Shen B, Mei Y, Yan Q, Jiang F, Chen F, Liu F. Song C, et al. JOR Spine. 2025 Jan 20;8(1):e70036. doi: 10.1002/jsp2.70036. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39835270 Free PMC article.

162

A Novel Dynamic Growth Rod Inducing Spinal Growth Modulation for the Correction of Spinal Deformities.

Xu Y, Lu D, Zhang L, Zhang S, Wu Y, Li H, Pei B, Wu X. Xu Y, et al. JOR Spine. 2025 Jan 10;8(1):e70031. doi: 10.1002/jsp2.70031. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39801572 Free PMC article.

163

Posterior Ligamentum Complex Preservation Alleviate ASD-Related Biomechanical Deterioration in Lumbar Interbody Fusion Models: A Finite Element Analysis.

He L, Zhu T, Cai W, Yang W, Chen Z, Li J. He L, et al. JOR Spine. 2025 Jan 7;8(1):e70030. doi: 10.1002/jsp2.70030. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39781090 Free PMC article.

164

The Relationship Between ADAMTS-4 and ADAMTS-5 Enzyme Levels in Patients With Degenerative Disc Disease: A Prospective Biochemical Study.

Tuncer C, Eminoğlu EM, Yağlı ÖE, Baş G, Topal AS, Onur E, Özdemir H, Yılmaz ŞG, Ovalı GY, Temiz C. Tuncer C, et al. JOR Spine. 2025 Jan 8;8(1):e70037. doi: 10.1002/jsp2.70037. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39781089 Free PMC article.

165

Enhancing Clinical Insights: New Radiographic Grading for Lumbar Facet Joint Degeneration, A Reliability Study.

Liu X, Zhu Z, He S, Sun M, Zhao T, Liu L, Shi H, Hou Y, Shi G. Liu X, et al. JOR Spine. 2025 Jan 7;8(1):e70035. doi: 10.1002/jsp2.70035. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39781088 Free PMC article.

166

Analysis of Key Differential Metabolites in Intervertebral Disc Degeneration Based on Untargeted Metabolomics.

Zhou D, Zhang X, Lv J, Mei Y, Luo Y, Li F, Liu Z. Zhou D, et al. JOR Spine. 2025 Jan 8;8(1):e70032. doi: 10.1002/jsp2.70032. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39781087 Free PMC article.

167

Exploring the Causal Relationship Between the Plasma Levels of MMP1 (Matrix Metalloproteinase-1), MMP3, MMP7, MMP10, and MMP12 and Intervertebral Disc Degeneration: Mendelian Randomization.

Sun L, Yan KQ, Zhang Q, Ma J, Shi B, Yang XY, Li LJ. Sun L, et al. JOR Spine. 2025 Jan 7;8(1):e70034. doi: 10.1002/jsp2.70034. eCollection 2025 Mar. JOR Spine. 2025. PMID: 39781086 Free PMC article.

168

In vitro and ex vivo screening of microRNA combinations with enhanced cell penetrating peptides to stimulate intervertebral disc regeneration.

Ní Néill T, Barcellona MN, Wilson N, O'Brien FJ, Dixon JE, Curtin CM, Buckley CT. Ní Néill T, et al. JOR Spine. 2024 Dec 25;7(4):e1366. doi: 10.1002/jsp2.1366. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39726900 Free PMC article.

169

How to improve the mechanical safety of a novel spinal implant while saving costs and time.

Kienle A, Wilke HJ, Schröder C, Pietsch A. Kienle A, et al. JOR Spine. 2024 Dec 25;7(4):e70026. doi: 10.1002/jsp2.70026. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39726899 Free PMC article. Review.

170

CD24 Positive Nucleus Pulposus Cells in Adult Human Intervertebral Discs Maintain a More Notochordal Phenotype Than GD2 Positive Cells.

Ionescu AM, Baird P, Patel S, Howell G, Hoyland JA, Richardson SM. Ionescu AM, et al. JOR Spine. 2024 Dec 23;7(4):e70029. doi: 10.1002/jsp2.70029. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39717383 Free PMC article.

171

Bone morphogenetic proteins, DNA methylation, and gut microbiota interaction in lumbar disc degeneration: A multi-omics Mendelian randomization study.

Li XY, Wang PY, Wang QJ, Wang DF, Wang SK, Wang Y, Zhu WG, Wang W, Kong C, Lu SB, Chen XL. Li XY, et al. JOR Spine. 2024 Dec 20;7(4):e70027. doi: 10.1002/jsp2.70027. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39713086 Free PMC article.

172

pH: A major player in degenerative intervertebral disks.

Trone MAR, Stover JD, Almarza A, Bowles RD. Trone MAR, et al. JOR Spine. 2024 Dec 18;7(4):e70025. doi: 10.1002/jsp2.70025. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39703199 Free PMC article. Review.

173

Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration.

Sun H, Guo J, Xiong Z, Zhuang Y, Ning X, Liu M. Sun H, et al. JOR Spine. 2024 Dec 18;7(4):e70011. doi: 10.1002/jsp2.70011. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39703198 Free PMC article. Review.

174

Scoliosis instrumentation alters primary and coupled motions of the spine: An in vitro study using entire thoracolumbar spine and rib cage specimens.

Liebsch C, Obid P, Vogt M, Schlager B, Wilke HJ. Liebsch C, et al. JOR Spine. 2024 Dec 18;7(4):e70028. doi: 10.1002/jsp2.70028. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39703197 Free PMC article.

175

The genetic causal association between arthritis and low back pain.

Gong A, Yang D, Zeng M. Gong A, et al. JOR Spine. 2024 Dec 13;7(4):e70023. doi: 10.1002/jsp2.70023. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39678046 Free PMC article.

176

Investigating the causal links between inflammatory cytokines and scoliosis through bidirectional Mendelian randomization analysis.

Mardan M, Mamat M, Yasin P, Cai X, Zheng H, Xu Q, Song S, Li B, Cai H, Chen P, Lu Z, Omar S, Jiang S, Jiang L, Zheng XF. Mardan M, et al. JOR Spine. 2024 Dec 11;7(4):e70019. doi: 10.1002/jsp2.70019. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39664590 Free PMC article.

177

Exploring the therapeutic potential of puerarin on intervertebral disc degeneration by regulating apoptosis of nucleus pulposus cells.

Wang X, Song C, Zhou D, Mei Y, Cai W, Chen R, Lv J, Shi H, Liu Z. Wang X, et al. JOR Spine. 2024 Dec 11;7(4):e70020. doi: 10.1002/jsp2.70020. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39664589 Free PMC article.

178

Clinical efficacy and biomechanical analysis of a novel hollow pedicle screw combined with kyphoplasty for the treatment of Kümmell disease.

Zhong S, Zhong H, Huang K, Zhao Y, Lei W, Li W. Zhong S, et al. JOR Spine. 2024 Dec 6;7(4):e70017. doi: 10.1002/jsp2.70017. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39649796 Free PMC article.

179

Correction to "Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs".

[No authors listed] [No authors listed] JOR Spine. 2024 Nov 26;7(4):e70013. doi: 10.1002/jsp2.70013. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39600966 Free PMC article.

180

Distinct clinical characteristics of adolescent idiopathic scoliosis with asymmetrical ESR1 expression in paraspinal muscle progenitor cells.

Xin H, Sui W, Mao W, Yang J, Shao X. Xin H, et al. JOR Spine. 2024 Nov 26;7(4):e70018. doi: 10.1002/jsp2.70018. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39600965 Free PMC article.

181

The effects of extracellular matrix-degrading enzymes polymorphisms on intervertebral disc degeneration.

Zhao D, Dou YX, Zeng LF, Han YH, Lin FZ, Xu NJ, Liu J, Zeng YP. Zhao D, et al. JOR Spine. 2024 Nov 20;7(4):e70012. doi: 10.1002/jsp2.70012. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39568776 Free PMC article. Review.

182

Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration.

Hagger G, Guest S, Birchall S, Bradley A, Brindley C, Corbett D, Cummings PJ, Freire C, Harris J, Wise A, Wood M, Czaplewski LG. Hagger G, et al. JOR Spine. 2024 Nov 14;7(4):e70010. doi: 10.1002/jsp2.70010. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39544355 Free PMC article.

183

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study.

Tripathi SS, Sneath R, Golash A, Desai P, McHale D, Guest S, Brindley C, Cummings P, Smith S, Stroud C, Scott G, Ruston S, Czaplewski L. Tripathi SS, et al. JOR Spine. 2024 Nov 14;7(4):e70009. doi: 10.1002/jsp2.70009. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39544354 Free PMC article.

184

Effect of cigarette smoke exposure and cessation on regional diffusion properties in rat intervertebral discs.

Kelley J, Buchweitz N, Madden A, Fan H, Hepfer G, Kern M, Townsend DM, Ye T, Yao H, Wu Y. Kelley J, et al. JOR Spine. 2024 Nov 14;7(4):e70015. doi: 10.1002/jsp2.70015. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39544353 Free PMC article.

185

Melatonin attenuates degenerative disc degression by downregulating DLX5 via the TGF/Smad2/3 pathway in nucleus pulposus cells.

Zhang K, Wang H, Mo L, Huang X, Yuan C, Liu C. Zhang K, et al. JOR Spine. 2024 Nov 13;7(4):e70014. doi: 10.1002/jsp2.70014. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39539538 Free PMC article.

186

The proteomic landscape of extracellular vesicles derived from human intervertebral disc cells.

Li L, Al-Jallad H, Sun A, Georgiopoulos M, Bokhari R, Ouellet J, Jarzem P, Cherif H, Haglund L. Li L, et al. JOR Spine. 2024 Nov 5;7(4):e70007. doi: 10.1002/jsp2.70007. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39507593 Free PMC article.

187

Finite element analysis of two-level discontinuous cervical hybrid revision surgery strategy to reduce biomechanical responses of adjacent segments.

Liang W, Sun D, Han B, Yang Y, Yin P, Hai Y. Liang W, et al. JOR Spine. 2024 Oct 31;7(4):e70008. doi: 10.1002/jsp2.70008. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39483258 Free PMC article.

188

A novel spine tester TO GO.

Jansen JU, Zengerle L, Steiner M, Sciortino V, Tryfonidou M, Wilke HJ. Jansen JU, et al. JOR Spine. 2024 Oct 27;7(4):e70002. doi: 10.1002/jsp2.70002. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39469185 Free PMC article.

189

Identifying critical modules and biomarkers of intervertebral disc degeneration by using weighted gene co-expression network.

Zhou D, Liu T, Mei Y, Lv J, Cheng K, Cai W, Gao S, Guo D, Xie X, Liu Z. Zhou D, et al. JOR Spine. 2024 Oct 18;7(4):e70004. doi: 10.1002/jsp2.70004. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39430414 Free PMC article.

190

Gut microbiome dysbiosis is associated with lumbar degenerative spondylolisthesis in symptomatic patients.

Aboushaala K, Chee AV, Adnan D, Toro SJ, Singh H, Savoia A, Dhillon ES, Yuh C, Dourdourekas J, Patel IK, Vucicevic R, Espinoza-Orias AA, Martin JT, Oh C, Keshavarzian A, Albert HB, Karppinen J, Kocak M, Wong AYL, Goldberg EJ, Phillips FM, Colman MW, Williams FMK, Borgia JA, Naqib A, Green SJ, Forsyth CB, An HS, Samartzis D. Aboushaala K, et al. JOR Spine. 2024 Oct 10;7(4):e70005. doi: 10.1002/jsp2.70005. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39398942 Free PMC article.

191

Inactivation of Tnf-α/Tnfr signaling attenuates progression of intervertebral disc degeneration in mice.

Tao C, Lin S, Shi Y, Gong W, Chen M, Li J, Zhang P, Yao Q, Qian D, Ling Z, Xiao G. Tao C, et al. JOR Spine. 2024 Oct 8;7(4):e70006. doi: 10.1002/jsp2.70006. eCollection 2024 Dec. JOR Spine. 2024. PMID: 39391171 Free PMC article.

192

Deep learning-based structure segmentation and intramuscular fat annotation on lumbar magnetic resonance imaging.

Xu Y, Zheng S, Tian Q, Kou Z, Li W, Xie X, Wu X. Xu Y, et al. JOR Spine. 2024 Sep 17;7(3):e70003. doi: 10.1002/jsp2.70003. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39291096 Free PMC article.

193

Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs.

Yao YC, Lin CL, Chen HH, Lin HH, Hsiung W, Wang ST, Sun YC, Tang YH, Chou PH. Yao YC, et al. JOR Spine. 2024 Sep 17;7(3):e70001. doi: 10.1002/jsp2.70001. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39291095 Free PMC article.

194

Neural network segmentation of disc volume from magnetic resonance images and the effect of degeneration and spinal level.

Markhali MI, Peloquin JM, Meadows KD, Newman HR, Elliott DM. Markhali MI, et al. JOR Spine. 2024 Sep 4;7(3):e70000. doi: 10.1002/jsp2.70000. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39234532 Free PMC article.

195

Protective effects of curcumin against spinal cord injury.

Razavi SM, Khayatan D, Najafi Arab Z, Hosseini Y, Khanahmadi M, Momtaz S, Jamialahmadi T, Johnston TP, Abdolghaffari AH, Sahebkar A. Razavi SM, et al. JOR Spine. 2024 Aug 14;7(3):e1364. doi: 10.1002/jsp2.1364. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39144499 Free PMC article. Review.

196

Clinical implications of linking microstructure, spatial biochemical, spatial biomechanical, and radiological features in ligamentum flavum degeneration.

Azril A, Huang KY, Liu HY, Liao WA, Liu WL, Hobley J, Jeng YR. Azril A, et al. JOR Spine. 2024 Aug 9;7(3):e1365. doi: 10.1002/jsp2.1365. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39132509 Free PMC article.

197

Biomolecular therapies for chronic discogenic low back pain: A narrative review.

Rudnik-Jansen I, van Kruining Kodele S, Creemers L, Joosten B. Rudnik-Jansen I, et al. JOR Spine. 2024 Aug 6;7(3):e1345. doi: 10.1002/jsp2.1345. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39114580 Free PMC article. Review.

198

Flexible support material maintains disc height and supports the formation of hydrated tissue engineered intervertebral discs in vivo.

Fidai AB, Kim B, Lintz M, Kirnaz S, Gadjradj P, Boadi BI, Koga M, Hussain I, Härtl R, Bonassar LJ. Fidai AB, et al. JOR Spine. 2024 Aug 5;7(3):e1363. doi: 10.1002/jsp2.1363. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39104832 Free PMC article.

199

The potential effect of romosozumab on perioperative management for instrumentation surgery.

Ishikawa K, Tani S, Toyone T, Tsuchiya K, Towatari T, Oshita Y, Yamamura R, Wada K, Nagai T, Shirahata T, Inagaki K, Yoshifumi K. Ishikawa K, et al. JOR Spine. 2024 Aug 5;7(3):e1356. doi: 10.1002/jsp2.1356. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39104831 Free PMC article.

200

Cryopreserving the intact intervertebral disc without compromising viability.

Shalash W, Forcier R, Higgins AZ, Giers MB. Shalash W, et al. JOR Spine. 2024 Aug 5;7(3):e1351. doi: 10.1002/jsp2.1351. eCollection 2024 Sep. JOR Spine. 2024. PMID: 39104830 Free PMC article.

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