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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 36
1978 132
1979 218
1980 246
1981 323
1982 435
1983 709
1984 720
1985 832
1986 891
1987 853
1988 873
1989 970
1990 907
1991 768
1992 711
1993 740
1994 732
1995 669
1996 726
1997 649
1998 670
1999 759
2000 801
2001 818
2002 812
2003 845
2004 888
2005 1014
2006 1014
2007 1086
2008 1107
2009 972
2010 992
2011 1053
2012 984
2013 1048
2014 1111
2015 1082
2016 1028
2017 975
2018 918
2019 399
2020 13
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31,766 results
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Page 1
Natural killer cells as a promising therapeutic target for cancer immunotherapy.
Kim N, et al. Arch Pharm Res 2019 - Review. PMID 30895524
Natural killer (NK) cells are innate lymphoid cells that provide early protection against cancer development via their selectivity to kill abnormal cells undergoing cellular transformation without the need for prior stimulation. ...Furthermore, MHC-unrestricted tumor lysis by NK cells complements the MHC-restricted killing of tumor cells by cytotoxic T cells, thus positioning NK cells as an alternative or complementary therapeutic target for cancers that are refractory to T cell-based therapy. ...
Natural killer (NK) cells are innate lymphoid cells that provide early protection against cancer development via
Liver natural killer cells: subsets and roles in liver immunity.
Peng H, et al. Cell Mol Immunol 2016 - Review. PMID 26639736 Free PMC article.
With a predominant role in innate immunity, the liver is enriched with various innate immune cells, among which natural killer (NK) cells play important roles in host defense and in maintaining immune balance. Hepatic NK cells were first described as 'pit cells' in the rat liver in the 1970s. Recent studies of NK cells in mouse and human livers have shown that two distinct NK cell subsets, liver-resident NK cells and conventional NK (cNK) cells, are present in this organ. ...
With a predominant role in innate immunity, the liver is enriched with various innate immune cells, among which natural kil
Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy.
Luna JI, et al. Expert Opin Biol Ther 2017 - Review. PMID 27960589 Free PMC article.
Areas covered: Natural killer (NK) cells have long been known for their ability to reject allogeneic hematopoietic stem cells, and there are increasing data demonstrating that NK cells can selectively identify and lyse CSCs. ...Expert opinion: Unlike cytotoxic cancer treatments, NK cells can target and eliminate quiescent/non-proliferating cells such as CSCs, and these enigmatic cells are an important source of relapse and metastasis. ...
Areas covered: Natural killer (NK) cells have long been known for their ability to reject allogeneic hematopoietic stem …
Natural killer cells as modulators of alloimmune responses.
Mbiribindi B, et al. Curr Opin Organ Transplant 2019 - Review. PMID 30480641
PURPOSE OF REVIEW: Natural killer (NK) cells are effector cells of the innate immune system that can lyse target cells without prior sensitization and are important in host defense to virally infected and transformed cells. ...Furthermore, NK cells respond to cells infected with cytomegalovirus and Epstein-Barr virus, and studies suggest some NK cells have immune memory. ...
PURPOSE OF REVIEW: Natural killer (NK) cells are effector cells of the innate immune system that can lyse target …
Challenges of NK cell-based immunotherapy in the new era
Fang F, et al. Front Med 2018 - Review. PMID 30047028
Natural killer cells (NKs) have a great potential for cancer immunotherapy because they can rapidly and directly kill transformed cells in the absence of antigen presensitization. Various cellular sources, including peripheral blood mononuclear cells (PBMCs), stem cells, and NK cell lines, have been used for producing NK cells. ...
Natural killer cells (NKs) have a great potential for cancer immunotherapy because they can rapidly and directly kill t
Harnessing adaptive natural killer cells in cancer immunotherapy.
Liu LL, et al. Mol Oncol 2015 - Review. PMID 26604011 Free PMC article.
Natural killer (NK) cells are innate lymphocytes with a refined ability to recognize transformed cells through a broad array of activating receptors in combination with stochastically expressed inhibitory receptors that recognize MHC-class I. ...Here, we discuss how new insights into the adaptive behavior of NK cells pave the way for next generation cell therapy based on guided differentiation and selective expansion of particularly cytotoxic NK cell subsets....
Natural killer (NK) cells are innate lymphocytes with a refined ability to recognize transformed cells through a
The trafficking of natural killer cells.
Grégoire C, et al. Immunol Rev 2007 - Review. PMID 17979846
Natural killer (NK) cells are large granular lymphocytes of the innate immune system that participate in the early control of microbial infections and cancer. NK cells can induce the death of autologous cells undergoing various forms of stress, recognizing and providing non-microbial 'danger' signals to the immune system. ...
Natural killer (NK) cells are large granular lymphocytes of the innate immune system that participate in the early cont
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