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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1978 3
1979 3
1980 1
1981 7
1982 13
1983 34
1984 39
1985 61
1986 49
1987 31
1988 60
1989 73
1990 60
1991 53
1992 63
1993 82
1994 85
1995 86
1996 125
1997 154
1998 143
1999 194
2000 232
2001 208
2002 220
2003 283
2004 297
2005 334
2006 329
2007 368
2008 408
2009 376
2010 401
2011 455
2012 417
2013 440
2014 421
2015 370
2016 369
2017 331
2018 346
2019 156
2020 4
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7,550 results
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Page 1
Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy.
Bollino D and Webb TJ. Transl Res 2017 - Review. PMID 28651074 Free PMC article.
Natural killer (NK) cells of the innate immune system and natural killer T (NKT) cells, which have roles in both the innate and adaptive responses, are unique lymphocyte subsets that have similarities in their functions and phenotypes. ...CAR-modified NK and NKT cells are becoming more prevalent because they provide a method to direct these cells more specifically to target cancer cells, with less risk of adverse effects. ...
Natural killer (NK) cells of the innate immune system and natural killer T (NKT) cells, which have
Immunometabolism and natural killer cell responses.
O'Brien KL and Finlay DK. Nat Rev Immunol 2019 - Review. PMID 30808985
Natural killer (NK) cells are lymphocytes with important roles in innate and adaptive immune responses to tumours and viral infection. ...Furthermore, it explores how defects in metabolism can contribute to the generation of dysfunctional NK cells in chronic disease. ...
Natural killer (NK) cells are lymphocytes with important roles in innate and adaptive immune responses to tumours and v
Natural killer cells and tumor metastasis.
Lee HH, et al. Arch Pharm Res 2017 - Review. PMID 28871566
Natural killer (NK) cells are cytotoxic lymphocytes that recognize tumor cells or stressed cells through 'missing-self' signals, such as altered or absent expression of MHC class I molecules. The function of NK cells is regulated by the activation or inhibition of receptors present on their surface. The activation of NK cells results in cytotoxic activity on target cells through release of toxic granules and inflammatory cytokines. ...
Natural killer (NK) cells are cytotoxic lymphocytes that recognize tumor cells or stressed cells through
Balancing natural killer cell activation through paired receptors.
Martinet L and Smyth MJ. Nat Rev Immunol 2015 - Review. PMID 25743219
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections and malignancies. NK cells express a variety of inhibitory and activating receptors that facilitate fine discrimination between damaged and healthy cells. ...
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections and malignancies. NK
Natural killer cells in malignant hematology: A primer for the non-immunologist.
Kannan GS, et al. Blood Rev 2017 - Review. PMID 27665023
Natural killer cells were first described over 40years ago, but the last 15years has shown tremendous progress in our understanding of their biology and our ability to manipulate them for clinical therapeutic effect. ...While they are microscopically indistinguishable from T cells and share many of the same effector functions, their mechanisms of target recognition are completely distinct from yet complimentary to T cells. ...
Natural killer cells were first described over 40years ago, but the last 15years has shown tremendous progress in our u
Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells.
Sharma S, et al. Genome Biol 2019. PMID 30791937 Free PMC article.
RESULTS: Here, we show that the related cytidine deaminase, APOBEC3G, induces site-specific C-to-U RNA editing in natural killer cells, lymphoma cell lines, and, to a lesser extent, CD8-positive T cells upon cellular crowding and hypoxia. ...RNA-seq analysis of natural killer cells subjected to cellular crowding and hypoxia reveals widespread C-to-U mRNA editing that is enriched for genes involved in mRNA translation and ribosome function. ...
RESULTS: Here, we show that the related cytidine deaminase, APOBEC3G, induces site-specific C-to-U RNA editing in natural killer
Natural Killer Cells--An Epigenetic Perspective of Development and Regulation.
Schenk A, et al. Int J Mol Sci 2016 - Review. PMID 26938533 Free PMC article.
Based on their ability to recognize and eliminate various endo- and exogenous pathogens as well as pathological alterations, Natural Killer (NK) cells represent an important part of the cellular innate immune system. ...
Based on their ability to recognize and eliminate various endo- and exogenous pathogens as well as pathological alterations, Natural
Metabolic regulation of natural killer cells.
Finlay DK. Biochem Soc Trans 2015 - Review. PMID 26551725
Natural killer (NK) cells have key roles in anti-viral and anti-tumour immune responses. Recent research demonstrates that cellular metabolism is an important determinant for the function of pro-inflammatory immune cells, including activated NK cells. ...This article will discuss the regulation of cellular metabolism in NK cells as compared with that of T lymphocytes and discuss the implications for NK cell responses to viral infection and cancer....
Natural killer (NK) cells have key roles in anti-viral and anti-tumour immune responses. Recent research demonstrates t
The Role of Natural Killer Cells in Humoral Rejection.
Resch T, et al. Transplantation 2015 - Review. PMID 26018352
This review summarizes the accumulating evidence for the contribution of natural killer cells, the key mediators of antibody-dependent cellular cytotoxicity, to human AMR in allotransplantation and xenotransplantation and illustrates the current mechanistic conceptions drawn from animal models....
This review summarizes the accumulating evidence for the contribution of natural killer cells, the key mediators of ant …
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