Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1977 1
1979 2
1980 3
1981 1
1982 4
1983 5
1984 3
1985 4
1986 3
1988 2
1989 3
1990 3
1991 1
1992 9
1993 8
1994 7
1995 4
1996 3
1997 4
1998 2
1999 1
2000 3
2001 4
2002 4
2003 5
2004 7
2005 5
2006 1
2007 6
2008 5
2009 4
2010 1
2011 8
2012 6
2013 7
2014 8
2015 6
2016 5
2017 10
2018 5
2019 5
2020 10
2021 9
2022 10
2023 6
2024 7
2025 7
2026 9

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

220 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "steoroids"
Page 1
Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation.
Koronowski KB, Greco CM, Huang H, Kim JK, Fribourgh JL, Crosby P, Mathur L, Ren X, Partch CL, Jang C, Qiao F, Zhao Y, Sassone-Corsi P. Koronowski KB, et al. Cell Rep. 2021 Aug 3;36(5):109487. doi: 10.1016/j.celrep.2021.109487. Cell Rep. 2021. PMID: 34348140 Free PMC article.
Mass spectrometry analysis of the beta-hydroxybutyrylome in mouse liver revealed 891 sites of Kbhb within 267 proteins enriched for fatty acid, amino acid, detoxification, and one-carbon metabolic pathways. Kbhb inhibits S-adenosyl-L-homocysteine hydrolase (AHCY), a …
Mass spectrometry analysis of the beta-hydroxybutyrylome in mouse liver revealed 891 sites of Kbhb within 267 proteins enriched for fatty ac …
L- and D-S-(3-[18F]fluoropropyl)homocysteine.
Chopra A. Chopra A. 2012 Jan 10 [updated 2012 Feb 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Jan 10 [updated 2012 Feb 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21994969 Free Books & Documents. Review.
Investigators developed S-(2-[(18)F]fluoroethyl)-L-homocysteine, an analog of MET, as a possible agent for the imaging of cancerous tumors, but this agent was unstable in aqueous media and could be used for the detection of these lesions (5). In a continued effort t …
Investigators developed S-(2-[(18)F]fluoroethyl)-L-homocysteine, an analog of MET, as a possible agent for the imaging of canc …
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms.
Wang JN, Wang F, Ke J, Li Z, Xu CH, Yang Q, Chen X, He XY, He Y, Suo XG, Li C, Yu JT, Jiang L, Ni WJ, Jin J, Liu MM, Shao W, Yang C, Gong Q, Chen HY, Li J, Wu YG, Meng XM. Wang JN, et al. Sci Transl Med. 2022 Apr 13;14(640):eabk2709. doi: 10.1126/scitranslmed.abk2709. Epub 2022 Apr 13. Sci Transl Med. 2022. PMID: 35417191
METTL3 silencing alleviated renal inflammation and programmed cell death in TECs in response to stimulation by tumor necrosis factor-alpha (TNF-alpha), cisplatin, and lipopolysaccharide (LPS), whereas METTL3 overexpression had the opposite effects. ...We further identified …
METTL3 silencing alleviated renal inflammation and programmed cell death in TECs in response to stimulation by tumor necrosis factor- …
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner.
Huang W, Li N, Zhang Y, Wang X, Yin M, Lei QY. Huang W, et al. Autophagy. 2022 Feb;18(2):309-319. doi: 10.1080/15548627.2021.1924038. Epub 2021 May 16. Autophagy. 2022. PMID: 33993848 Free PMC article.
S-adenosyl-l-homocysteine (SAH), an amino acid derivative, is a key intermediate metabolite in methionine metabolism, which is normally considered as a harmful by-product and hydrolyzed quickly once formed. ...Our study uncovers a new axis of SAH-AHCYL1-PIK3C3, whic …
S-adenosyl-l-homocysteine (SAH), an amino acid derivative, is a key intermediate metabolite in methionine metabolism, which is …
Hydrogen sulfide and endothelium-dependent vasorelaxation.
Bełtowski J, Jamroz-Wiśniewska A. Bełtowski J, et al. Molecules. 2014 Dec 16;19(12):21183-99. doi: 10.3390/molecules191221183. Molecules. 2014. PMID: 25521118 Free PMC article. Review.
In addition to nitric oxide and carbon monoxide, hydrogen sulfide (H2S), synthesized enzymatically from l-cysteine or l-homocysteine, is the third gasotransmitter in mammals. Endogenous H2S is involved in the regulation of many physiological processes, including vas …
In addition to nitric oxide and carbon monoxide, hydrogen sulfide (H2S), synthesized enzymatically from l-cysteine or l-homocystei …
Nicotinamide N-methyltransferase (NNMT): A key enzyme in cancer metabolism and therapeutic target.
Sun WD, Zhu XJ, Li JJ, Mei YZ, Li WS, Li JH. Sun WD, et al. Int Immunopharmacol. 2024 Dec 5;142(Pt B):113208. doi: 10.1016/j.intimp.2024.113208. Epub 2024 Sep 22. Int Immunopharmacol. 2024. PMID: 39312861 Review.
This increased presence is tightly linked to tumor initiation, proliferation, and metastasis. The enzymatic function of NNMT is centered on the methylation of nicotinamide (NAM), utilizing S-adenosylmethionine (SAM) as the methyl donor, which results in the generation of S …
This increased presence is tightly linked to tumor initiation, proliferation, and metastasis. The enzymatic function of NNMT is cente …
Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges.
Chen Y, Liu X, Li Y, Quan C, Zheng L, Huang K. Chen Y, et al. Comput Struct Biotechnol J. 2018 Jun 20;16:211-223. doi: 10.1016/j.csbj.2018.06.001. eCollection 2018. Comput Struct Biotechnol J. 2018. PMID: 30002791 Free PMC article. Review.
Lung cancer is one of the most common malignancies. In spite of the progress made in past decades, further studies to improve current therapy for lung cancer are required. ...Aberrant alterations of histone methylation have been demonstrated to be associated with th …
Lung cancer is one of the most common malignancies. In spite of the progress made in past decades, further studies to improve current …
S-adenosyl-L-homocysteine Hydrolase: Its Inhibitory Activity Against Plasmodium falciparum and Development of Malaria Drugs.
Chandra G, Patel S, Panchal M, Singh DV. Chandra G, et al. Mini Rev Med Chem. 2021;21(7):833-846. doi: 10.2174/1389557521666201218155321. Mini Rev Med Chem. 2021. PMID: 33342411 Review.
One of the potential mechanisms is to hamper protein synthesis by blocking the gene expression. S-Adenosyl-L-homocysteine (SAH) hydrolase is a NAD+ dependent tetrameric enzyme, which is responsible for the reversible hydrolysis of AdoHcy to adenosine and L- …
One of the potential mechanisms is to hamper protein synthesis by blocking the gene expression. S-Adenosyl-L-homocysteine (SAH …
Elevated homocysteine levels and risk of cardiovascular and all-cause mortality: a meta-analysis of prospective studies.
Peng HY, Man CF, Xu J, Fan Y. Peng HY, et al. J Zhejiang Univ Sci B. 2015 Jan;16(1):78-86. doi: 10.1631/jzus.B1400183. J Zhejiang Univ Sci B. 2015. PMID: 25559959 Free PMC article.
Comparing the highest to lowest homocysteine level categories, CHD mortality increased by 66% (RR 1.66; 95% CI 1.12-2.47; P=0.012), cardiovascular mortality increased by 68% (RR 1.68; 95% CI 1.04-2.70; P=0.033), and all-cause mortality increased by 93% (RR 1.93; 95% CI 1.54-2.43; …
Comparing the highest to lowest homocysteine level categories, CHD mortality increased by 66% (RR 1.66; 95% CI 1.12-2.47; P=0.012), cardiova …
On the mechanism of homocysteine pathophysiology and pathogenesis: a unifying hypothesis.
Zhu BT. Zhu BT. Histol Histopathol. 2002 Oct;17(4):1283-91. doi: 10.14670/HH-17.1283. Histol Histopathol. 2002. PMID: 12371153 Review.
In this paper, a unifying hypothesis is proposed which suggests that hyperhomocysteinemia may exert its pathogenic effects largely through metabolic accumulation of S-adenosyl-L-homocysteine, a strong noncompetitive inhibitor of the catechol-O-methyltransferase (COM …
In this paper, a unifying hypothesis is proposed which suggests that hyperhomocysteinemia may exert its pathogenic effects largely through m …
220 results