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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 13
1946 48
1947 67
1948 47
1949 60
1950 46
1951 44
1952 48
1953 53
1954 56
1955 40
1956 65
1957 76
1958 75
1959 87
1960 64
1961 86
1962 84
1963 80
1964 114
1965 34
1966 1
1968 1
1970 3
1972 1
1974 3
1975 4
1976 1
1977 4
1978 1
1979 7
1980 12
1981 260
1982 396
1983 420
1984 562
1985 535
1986 535
1987 462
1988 427
1989 435
1990 476
1991 587
1992 578
1993 718
1994 781
1995 712
1996 737
1997 785
1998 933
1999 960
2000 1095
2001 1123
2002 1147
2003 1224
2004 1246
2005 1381
2006 1588
2007 1552
2008 1663
2009 1744
2010 1886
2011 2043
2012 2296
2013 2351
2014 2420
2015 2447
2016 2172
2017 2028
2018 1598
2019 681
2020 13
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41,856 results
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Page 1
Lactic Acid Production from a Whole Slurry of Acid-Pretreated Spent Coffee Grounds by Engineered Saccharomyces cerevisiae.
Kim JW, et al. Appl Biochem Biotechnol 2019. PMID 30969397
Lactic acid bacteria fermentation is the primary source of generation of lactic acid, a monomer of polylactic acid that has various industrial applications; however, because of the low tolerance of lactic acid bacteria to toxic compounds, it is necessary to apply Saccharomyces cerevisiae to produce lactic acid whose tolerance to toxic compounds is higher. ...Thus, fermentation of whole slurry SCG by engineered S. cerevisiae is a suitable way of lactic acid production, selectively....
Lactic acid bacteria fermentation is the primary source of generation of lactic acid, a monomer of polylactic
Electrolyzing lactic acid in situ in fermentation broth to produce pyruvic acid in electrolysis cell.
Xixi Z, et al. Appl Microbiol Biotechnol 2019. PMID 30944959
Here, pyruvic acid generation from direct conversion of lactic acid in fermentation broth by electrolysis method is presented. It was found that lactic acid could be converted to pyruvic acid in the electrolysis cell under alkaline conditions. Using 12.53 g/L lactic acid fermentation broth as anolyte, 7.01 g/L pyruvic acid could be produced and productivity to lactic acid was 57.66% at initial pH 11.74 and 5.0 V applied a voltage in the electrolysis cell. ...
Here, pyruvic acid generation from direct conversion of lactic acid in fermentation broth by electrolysis method is pre …
Oligo(Lactic Acid)(8)-Rapamycin Prodrug-Loaded Poly(Ethylene Glycol)-block-Poly(Lactic Acid) Micelles for Injection.
Tam YT, et al. Pharm Res 2019. PMID 30888509
PURPOSE: To prepare an oligo(lactic acid)(8)-rapamycin prodrug (o(LA)(8)-RAP)-loaded poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) micelle for injection and characterize its compatibility and performance versus a RAP-loaded PEG-b-PLA micelle for injection in vitro and in vivo. ...
PURPOSE: To prepare an oligo(lactic acid)(8)-rapamycin prodrug (o(LA)(8)-RAP)-loaded poly(ethylene glycol)-block-poly(lacti
Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development
Lee YS, et al. Cell Host Microbe 2018. PMID 30543778 Free article.
To clarify the role of lactic-acid-producing bacteria (LAB) on intestinal stem-cell (ISC)-mediated epithelial development, we fed mice with LAB-type symbionts such as Bifidobacterium and Lactobacillus spp. ...
To clarify the role of lactic-acid-producing bacteria (LAB) on intestinal stem-cell (ISC)-mediated epithelial development, we …
Analysis of hypoxanthine and lactic acid levels in vitreous humor for the estimation of post-mortem interval (PMI) using LC-MS/MS.
Go A, et al. Forensic Sci Int 2019. PMID 31003185
Following correction of the concentrations of Hx and l-lactic acid with temperature, the correlation of Hx and l-lactic acid with PMI increased from 0.53 to 0.59 for Hx and 0.38 to 0.42 for l-lactic acid. The highest correlation of Hx and l-lactic acid concentrations with PMI was observed in the winter season, with an R(2) value of 0.80 and 0.71 for Hx and l-lactic acid, respectively. ...
Following correction of the concentrations of Hx and l-lactic acid with temperature, the correlation of Hx and l-lactic
Engineering Lactococcus lactis for D-Lactic Acid Production from Starch.
Aso Y, et al. Curr Microbiol 2019. PMID 31302724
Bioprocess development is a current requirement to enhance the global production of D-lactic acid. Herein, we report a new bioprocess for D-lactic acid production directly from starch using engineered Lactococcus lactis NZ9000. ...Direct production of D-lactic acid from starch as the carbon source was demonstrated using L. lactis AH2, resulting in D-lactic acid production at a concentration of 15.0 g/L after 24 h cultivation. ...
Bioprocess development is a current requirement to enhance the global production of D-lactic acid. Herein, we report a new bio …
GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites
Morita N, et al. Nature 2019. PMID 30675063
Here we show in mice that the bacterial metabolites pyruvic acid and lactic acid induce dendrite protrusion via GPR31 in CX3CR1(+) cells. ...We purified a GPR31-activating fraction, and identified lactic acid. Both lactic acid and pyruvic acid induced dendrite extension of CX3CR1(+) cells of wild-type mice, but not of Gpr31b(-/-) mice. ...
Here we show in mice that the bacterial metabolites pyruvic acid and lactic acid induce dendrite protrusion via GPR31 i …
Metabolic engineering of Corynebacterium glutamicum for hyperproduction of polymer-grade L- and D-lactic acid.
Tsuge Y, et al. Appl Microbiol Biotechnol 2019. PMID 30877357
The stereo-complex form of polylactic acid, a complex of poly-L- and poly-D-lactic acid, is a promising polymer candidate due to its high thermotolerance. ...Finally, additional chromosomal overexpression of a gene encoding NADH dehydrogenase to modulate the redox balance resulted in the production of 212 g/L L-lactic acid with a 97.9% yield and 264 g/L D-lactic acid with a 95.0% yield. ...
The stereo-complex form of polylactic acid, a complex of poly-L- and poly-D-lactic acid, is a promising polymer candida …
41,856 results
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