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Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity.
Chen KY, Brychta RJ, Abdul Sater Z, Cassimatis TM, Cero C, Fletcher LA, Israni NS, Johnson JW, Lea HJ, Linderman JD, O'Mara AE, Zhu KY, Cypess AM. Chen KY, et al. Among authors: lea hj. J Biol Chem. 2020 Feb 14;295(7):1926-1942. doi: 10.1074/jbc.REV119.007363. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914415 Free PMC article. Review.
The thermoneutral zone in women takes an "arctic" shift compared to men.
Brychta RJ, McGehee S, Huang S, Leitner BP, Duckworth CJ, Fletcher LA, Kim K, Cassimatis TM, Israni NS, Lea HJ, Lentz TN, Pierce AE, Jiang A, LaMunion SR, Thomas RJ, Ishihara A, Courville AB, Yang SB, Reitman ML, Cypess AM, Chen KY. Brychta RJ, et al. Among authors: lea hj. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2311116121. doi: 10.1073/pnas.2311116121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683977 Free PMC article.