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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1981 1
1982 1
1985 1
1986 2
1987 12
1988 108
1989 329
1990 395
1991 430
1992 465
1993 445
1994 484
1995 522
1996 492
1997 587
1998 604
1999 645
2000 687
2001 652
2002 711
2003 775
2004 819
2005 993
2006 1113
2007 1179
2008 1201
2009 1235
2010 1326
2011 1424
2012 1437
2013 1312
2014 1257
2015 1337
2016 1186
2017 1159
2018 1073
2019 590
2020 13
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23,961 results
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Page 1
Ferroptosis Inhibition: Mechanisms and Opportunities
Angeli JPF, et al. Trends Pharmacol Sci 2017 - Review. PMID 28363764
Now with the establishment of a connection between lipid peroxidation and a distinctive cell death pathway, the search for new small molecules able to suppress lipid peroxidation has gained momentum and may yield novel cytoprotective strategies. We review here advances in our understanding of the ferroptotic process and summarize the development of lipid peroxidation inhibitors with the ultimate goal of suppressing ferroptosis-relevant cell death and related pathologies....
Now with the establishment of a connection between lipid peroxidation and a distinctive cell death pathway, the search for new …
CLINDAMYCIN: EFFECTS ON PLASMA LIPID PROFILE AND PEROXIDATION PARAMETERS IN RABBIT BLOOD PLASMA.
Devbhuti P, et al. Acta Pol Pharm 2015. PMID 26642675 Free article.
Alteration of plasma lipid profile and induction of lipid peroxidation may take place due to drug effect, which may be correlated with adverse drug reactions and drug-induced toxicity. ...After administering drug and antioxidant alone and in combination in rabbit, it was found that clindamycin had mild lipid peroxidation induction and profile alteration capacity, which can be arrested on co-administration of ascorbic acid....
Alteration of plasma lipid profile and induction of lipid peroxidation may take place due to drug effect, which …
4-Hydroxy-2-nonenal: a critical target in oxidative stress?
Breitzig M, et al. Am J Physiol Cell Physiol 2016 - Review. PMID 27385721 Free PMC article.
As a reactive aldehyde, and a product of lipid peroxidation, studies corroborate its ability to disrupt signal transduction and protein activity, as well as induce inflammation and trigger cellular apoptosis in conditions of oxidative stress. ...
As a reactive aldehyde, and a product of lipid peroxidation, studies corroborate its ability to disrupt signal transduction an …
Combined effects of holy basil essential oil and inlet temperature on lipid peroxidation and survival of Lactobacillus reuteri KUB-AC5 during spray drying.
Rodklongtan A and Chitprasert P. Food Res Int 2017. PMID 28873688
Lipid peroxidation induced by oxidative stress plays an important role in reducing probiotic survival during spray drying. In this study, the probiotic Lactobacillus reuteri KUB-AC5 was co-encapsulated with holy basil essential oil, HBEO (0, 6, and 12mg/ml), by spray drying using skim milk at inlet air temperatures of 130, 140, and 150°C. The microcapsule properties in terms of morphology, size, moisture content, water activity, surface oil, microencapsulation efficiency, antioxidant activity, lipid peroxidation, and cell survival were determined. ...
Lipid peroxidation induced by oxidative stress plays an important role in reducing probiotic survival during spray drying. In
circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis.
Guo XY, et al. Oxid Med Cell Longev 2017. PMID 29018509 Free PMC article.
Hepatic steatosis reflects the miRNA-related pathological disorder with triglyceride accumulation and lipid peroxidation, which leads to nonalcoholic steatohepatitis, liver fibrosis/cirrhosis, and even hepatocellular carcinoma. ...Hepatotoxicity of steatosis-related lipid peroxidation, being characterized by mitochondrial dysfunction, growth arrest, and apoptosis, is resultantly prevented after the circRNA_0046367 administration. ...
Hepatic steatosis reflects the miRNA-related pathological disorder with triglyceride accumulation and lipid peroxidation, whic …
Effect of some phytoconstituents on Fe2+/ascorbate induced lipid peroxidation.
Najar IA, et al. Indian J Exp Biol 2016. PMID 30183186
On the other hand, agnuside, andrographolide, picroside-I, negunoside, oleanolic acid, and glycerrihizin, showed enhancement in both basal and induced lipid peroxidation. Phytoconstituents which have decreased both basal and Fe2+/ascorbate induced lipid peroxidation may act as defensive against the deadly effects of ROS, causative agents of lipid peroxidation and other diseases either alone or in combination with diet/nutritional supplements....
On the other hand, agnuside, andrographolide, picroside-I, negunoside, oleanolic acid, and glycerrihizin, showed enhancement in both basal a …
Polyphenols Effect on Circulating Lipids and Lipoproteins: From Biochemistry to Clinical Evidence
Cicero AFG and Colletti A. Curr Pharm Des 2018 - Review. PMID 29189140
OBJECTIVE: The aim of this review is to focus the attention on the presumed lipid-lowering and atheroprotective effects of polyphenols, administered either as individual molecules (nutritional supplements) and as functional foods, on the basis of the evidence coming from randomized controlled trials (RCTs) and their meta-analyses. ...CONCLUSION: Polyphenols, if taken in adequate dosages, can exert in some cases a positive effect on the prevention of cardiovascular risk and lipid oxidation, despite an unclear effect on lipid levels....
OBJECTIVE: The aim of this review is to focus the attention on the presumed lipid-lowering and atheroprotective effects of pol …
Inhibitory effects of astragali radix, crude drug in Oriental medicines on lipid peroxidation and protein oxidative modification of mouse brain homogenate by copper.
Toda S, et al. Phytother Res 2000. PMID 10861978
It was shown to have inhibitory effects on lipid peroxidation and protein oxidative modification by copper. The effects were similar to and stronger than those of mannitol and superoxide dismutase as free radical scavengers. These results demonstrated that Astragali Radix has inhibitory effects on oxidative stress induced by metal....
It was shown to have inhibitory effects on lipid peroxidation and protein oxidative modification by copper. The effe
Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats.
Rodríguez-Gutiérrez G, et al. Eur J Nutr 2019. PMID 29808273
METHODS: The compounds' abilities to inhibit lipid peroxidation in liver microsomes obtained from vitamin E-deficient rats were compared to hydroxytyrosol. RESULTS: All synthetic compounds had a significant higher ability to inhibit lipid peroxidation than hydroxytyrosol. Selenium derivates displayed a higher antioxidant activity than sulphur derivatives. ...
METHODS: The compounds' abilities to inhibit lipid peroxidation in liver microsomes obtained from vitamin E-deficient rats wer …
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